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| 1 | Management of diabetic foot ulcers and the challenging points:An endocrine view显示文摘Diabetic foot ulcers(DFU)are one of the most challenging complications of diabetes.Up to one-third of patients with diabetes mellitus(DM)may suffer from DFUs during their life.DFU is one of the leading causes of morbidity in patients with DM.The treatment period is challenging,and the recurrence rate of DFUs is high.Hence,establishing prevention strategies is the most important point to be emphasized.A multidisciplinary approach is necessary in the prevention and treatment of DFUs.Patients at risk should be identified,and prevention measures should be taken based on the risk category.Once a DFU is formed,the appropriate classification and evidence-based treatment interventions should be executed.Glycemic control,diagnosis and treatment of vascular disease,local wound care,diagnosis,and treatment of infection should be addressed along with the proper evaluation and management of general health status. | Hakan Doğruel Mustafa Aydemir Mustafa Kemal Balci | 2022 | World Journal of Diabetes2022，13，1： | 8 |
| 2 | Biliary fistula after treatment for hydatid disease of the liver:When to intervene显示文摘AIM:To determine the outcome of patients with biliary fistula(BF)after treatment for hydatid disease of the liver. METHODS:Between January 2000 and December 2010,out of 301 patients with a diagnosis of hydatid cyst of the liver,282 patients who underwent treatment [either surgery or puncture,aspiration,injection and reaspiration(PAIR)procedure]were analysed.Patients were grouped according to the presence or absence of postoperative biliary fistula(PBF)(PBF vs no-PBF groups,respectively).Preoperative clinical,radiological and laboratory characteristics,operative characteristics including type of surgery,peroperative detection of BF,postoperative drain output,morbidity,mortality and length of hospital stays of patients were compared amongst groups.Multivariate analysis was performed to detect factors predictive of PBF.Receiver operative characteristics(ROC)curve analysis were used to determine ideal cutoff values for those variables found to be significant.A comparison was also made between patients whose fistula closed spontaneously(CS)and those with intervention in order to find predictive fac-tors associated with spontaneous closure. RESULTS:Among 282 patients[median(range)age, 23(16-78)years;77.0%male];210(74.5%)were treated with conservative surgery,33(11.7%)radical surgery and 39(13.8%)underwent percutaneous drainage with PAIR procedure A PBF developed in 46(16.3%) patients,all within 5 d after operation.The maximum cyst diameter and preoperative alkaline phosphatase levels(U/L)were significantly higher in the PBF group than in the no-PBF group[10.5±3.7 U/L vs 8.4±3.5 U/L(P<0.001)and 40.0±235.1 U/Lvs 190.0±167.3 U/L(P=0.02),respectively].Hospitalization time was also significantly longer in the PBF group than in the no-PBF group[37.4±18.0 d vs 22.4±17.9 d(P< 0.001)].A preoperative high alanine aminotransferase level(>40 U/L)and a peroperative attempt for fistula closure were significant predictors of PBF development (P=0.02,95%CI:-0.03-0.5 and P=0.001,95%CI:0.1-0.4),respectively.Comparison of patients whose PBF CS or with biliary intervention(BI)revealed that the mean diameter of the cyst was not significantly different between CS and BI groups however maximum drain output was significantly higher in the BI group(81.6± 118.1 cm vs 423.9±298.4 cm,P<0.001).Time for fistula closure was significantly higher in the BI group(10.1 ±3.7 d vs 30.7±15.1 d,P<0.001).The ROC curve analysis revealed cut-off values of a maximum bilious drainage<102 mL and a waiting period of 5.5 postoperative days for spontaneous closure with the sensitivity and specificity values of(83.3%-91.1%,AUC:0.90)and (97%-91%,AUC:0.95),respectively.The multivariate analysis demonstrated a PBF drainage volume<102 mL to be the only statistically significant predictor of spontaneous closure(P<0.001,95%CI:0.5-1.0). CONCLUSION:Patients with PBF after hydatid surgery often have complicated postoperative course with serious morbidity.Patients who develop PBF with an output <102 mL might be managed expectantly. | Nazif Zeybek Hakan Dede Deniz Balci Ali Kagan Coskun Ismail Hakki Ozerhan Subutay Peker Yusuf Peker | 2013 | World Journal of Gastroenterology2013，19，3： | 5 |
| 3 | Can platelet count/spleen diameter ratio be used for cirrhotic children to predict esophageal varices?显示文摘AIM To determine the laboratory and radiologic parameters, including the platelet count(PC)-to-spleen diameter(SD) ratio as a non-invasive marker that may predict the presence of esophageal varices(EV) in children with cirrhosis.METHODS Eighty-nine patients with cirrhosis, but without a history of variceal bleeding were prospectively included. The children were grouped into 6-12 and 12-18 years of age groups. These groups were also divided into 2 subgroups(presence and absence of EV). All of the patients underwent a complete biochemical and radiologic evaluation. The PC(n/mm^3)-to-SD(mm) ratio was calculated for each patient. RESULTS Sixty-nine of 98(70.4%) patients had EV. The presence of ascites in all age groups was significantly associatedwith the presence of EV. There were no differences in serum albumin levels, PC, SD and the PC-to-SD ratio between the presence and absence of EV groups in both age groups(P > 0.05). CONCLUSION Laboratory and radiologic parameters, including the PC-to-SD ratio as a non-invasive marker(except for the presence of ascites), was inappropriate for detecting EV in children with cirrhosis. | Oya Balci Sezer Deniz Celik Nihal Tutar Figen Ozcay | 2016 | World Journal of Hepatology2016，8，33： | 4 |
| 4 | Hepatic vein in living donor liver transplantation显示文摘Right lobe living donor liver transplantation(LDLT)is a major development in adult LDLT that has significantly increased the donor pool by providing larger graft size and by decreasing risk of small-for-size graft syndrome.However,right lobe anatomy is complex,not only from the inflow but also from the outflow perspective.Outflow reconstruction is one of the key requirements of a successful LDLT and venous drainage of the liver graft is just as important as hepatic inflow for the integrity of graft function.Outflow complications may cause acute graft failure which is not always easy to diagnose.The right lobe graft consists of two sections and three hepatic venous routes for drainage that require reconstruction.In order to obtain a congestion free graft,several types of vascular conduits and postoperative interventions are needed to assure an adequate venous allograft drainage.This review described the anatomy,functional basis and the evolution of outflow reconstruction in right lobe LDLT. | Deniz Balci Elvan Onur Kirimker | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，4： | 4 |
| 5 | High sensitivity and high selectivity terahertz biomedical imaging显示文摘We demonstrate two distinct emerging terahertz (THz) biomedical imaging techniques.One is based on the use of a new single frequency THz quantum cascade laser and the other is based on broadband THz time domain spectrocopy.The first method is employed to derive a metastasis lung tissue imaging at 3.7 THz with clear contrast between cancerous and healthy areas.The second approach is used to study an osseous tissue under several imaging modalities and achieve full THz spectroscopic imaging based on the frequency domain or on a fixed THz propagation time-delay.Sufficient contrast is achieved which facilitated the identification of regions with different cellular types and density compositions. | Seongsin M.Kim William Baughman David S.Wilbert Lee Butler Michael Bolus Soner Balci Patrick Kung | 2011 | Chinese Optics Letters2011，9，11： | 4 |
| 6 | Detection of class 1 integron in Acinetobacter baumannii isolates collected from nine hospitals in Turkey显示文摘Objective:To investigate the antibiotic resistance genes inserted into class I and class 2integrons in Acinetobacler baumannii[A.baumannii)isolates obtained from nine different cities in Turkey.Methods:A collection of 281 A.baumannii clinical isolates were collected from nine diferenl state hospitals in Turkey and were confirmed as A.baumannU by conventional biochemical,API testing and bla_(-OXA-51)specific PCR.The isolates were examined by PCR for existence of class I and2 integron gene cassettes.Results:They were characterized by antimicrobial susceptibility testing and the highest resistance rates were determined for piperacillin(90.03%),ciprofloxacin(87.54%),cefepime and trimethoprim/sulfamethoxazole(81.13%).The lowest resistance rates was for cefotaxime(3.55%).class 1 integrons were detected in 6.4%(18/281)of A.baumannii strains and no class 2 integron was detected.The gene casselles of class 1 inlegrons AacCI-AAC(3)l-aadAI,AacCI-aadA1,AAC(3)-I,AAC(3)-I-AAC(3)-I-aadA1,TEM-1.AAC(3)-I-aadA1-AAC(3)-I-AAC(3)-I,AAC(3)-I-AAC(3)-I-AAC(3)-I-aadA1,AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I,AAC(3)-I-aadA1-AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I-aadA1-AAC(3)-I-aadA1 were detected in eighteen strains.The aac genes family were most frequently found integrated into the class 1 inlegrons and it was followed by aadA genes and TEM-1 genes.Conclusions:This is an extensive study on the distribulion of class 1 integron among A.baumannii in Turkey.In addition to these,two new alleles were observed.Their percentage rates of similarity to other cassettes are 95%aadA1(TK A18)and 89%,aadA 1(ANKA3). | Aysegül Copur Cicek Azer Ozad Düzgün Aysegül Saral Tuba Kayman Zeynep Cizmeci Pervin Ozlem Balci Tuba Dal Mehmet Firat Ismail Tosun Yasemin Ay Alitntop Ahmet Caliskan Yelda Yazici Cemal Sandalli | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 3 |
| 7 | General characteristics of patients with electrolyte imbalance admitted to emergency department显示文摘BACKGROUND:Fluid and electrolyte balance is a key concept to understand for maintaining homeostasis,and for a successful treatment of many metabolic disorders.There are various regulating mechanisms for the equilibrium of electrolytes in organisms.Disorders of these mechanisms result in electrolyte imbalances that may be life-threatening clinical conditions.In this study we defined the electrolyte imbalance characteristics of patients admitted to our emergency department.METHODS:This study was conducted in the Emergency Department(ED) of Uludag University Faculty of Medicine,and included 996 patients over 18 years of age.All patients had electrolyte imbalance,with various etiologies other than traumatic origin.Demographic and clinical parameters were collected after obtaining informed consent from the patients.The ethical committee of the university approved this study.RESULTS:The mean age of the patients was 59.28±16.79,and 55%of the patients were male.The common symptoms of the patients were dyspnea(14.7%),fever(13.7%),and systemic deterioration(11.9%);but the most and least frequent electrolyte imbalances were hyponatremia and hypermagnesemia,respectively.Most frequent findings in physical examination were confusion(14%),edema(10%) and rales(9%);and most frequent pathological findings in ECG were tachycardia in24%,and atrial fibrillation in 7%of the patients.Most frequent comorbidity was malignancy(39%).Most frequent diagnoses in the patients were sepsis(11%),pneumonia(9%),and acute renal failure(7%).CONCLUSIONS:Electrolyte imbalances are of particular importance in the treatment of ED patients.Therefore,ED physicians must be acknowledged of their fluid-electrolyte balance dynamics and general characteristics. | Arif Kadri Balci Ozlem Koksal Ataman Kose Erol Armagan Fatma Ozdemir Taylan Inal Nuran Oner | 2013 | World Journal of Emergency Medicine2013，4，2： | 3 |
| 8 | Development of therapeutic options on type 2 diabetes in years:Glucagon-like peptide-1 receptor agonist’s role intreatment; from the past to future显示文摘Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia.Type 2 diabetes (T2DM) accounting for 90% of cases globally.The worldwide prevalence of DM is rising dramatically over the last decades,from 30 million cases in 1985 to 382 million cases in 2013.It’s estimated that 451 million people had diabetes in 2017.As the pathophysiology was understood over the years,treatment options for diabetes increased.Incretin-based therapy is one of them.Glucagon-like peptide-1 receptor agonist (GLP-1 RA) not only significantly lower glucose level with minimal risk of hypoglycemia but also,they have an important advantage in themanagement of cardiovascular risk and obesity.Thus,we will review here GLP-1 RAsrole in the treatment of diabetes. | Hakan Dogruel Mustafa Kemal Balci | 2019 | World Journal of Diabetes2019，10，8： | 3 |
| 9 | Safety and efficacy of sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation显示文摘 | Abhijeet Waghray Bengi Balci Galal El‐Gazzaz Richard Kim Robert Pelley KV Narayanan Menon Bassam Estfan Carlos Romero‐Marrero Federico Aucejo | 2013 | Clin Transplant2013，，4： | 3 |
| 10 | Dominant rock properties affecting the performance of conical picks and the comparison of some experimental and theoretical results显示文摘 | N. Bilgin M.A. Demircin H. Copur C. Balci H. Tuncdemir N. Akcin | 2005 | International Journal of Rock Mechanics and Mining Sciences2005，，1： | 2 |
| 11 | Dominant rock properties affecting the performance of conical picks and the comparison of some experimental and theoretical results显示文摘 | N. Bilgin M.A. Demircin H. Copur C. Balci H. Tuncdemir N. Akcin | 2005 | International Journal of Rock Mechanics and Mining Sciences2005，，1： | 2 |
| 12 | Determination of plasma microRNA for early detection of gastric cancer显示文摘 | Aysegul Gorur Senay Balci Fidanci Nil Dogruer Unal Lokman Ayaz Serin Akbayir Hatice Yildirim Yaroglu Musa Dirlik Mehmet Sami Serin Lulufer Tamer | 2013 | Molecular Biology Reports2013，，3： | 2 |
| 13 | Synthesis and characterization of Dy-Eu-Tm co-doped cubic phase stabilized bismuth oxide based electrolytes in terms of intermediate temperature-solid oxide fuel cells(IT-SOFCs)显示文摘In this study,a new Dy-Eu-Tm co-doped cubic phase stabilized bismuth oxide solid electrolyte system was synthesized by using solid-state reaction method in atmospheric conditions.Before conductivity measurements,X-ray diffraction(XRD)pro files of the annealed samples show that created mixtures have heterogeneous phase,but after conductivity measurements,the face-centered cubic(FCC)crystal structure is stabilized for all samples.Also,the increase in total dopant rate causes an increase in full width half maxima(FWHM)of main peak(111)on the XRD pattern while average crystal size decreases with it.On the other hand,the highest conductivity value was obtained for the sample having 15%total dopant rate with 0.62 S/cm at 750℃,whose dopants are evenly distributed in mole percent.Differential thermal analysis(DTA)results of the samples having 1:1:1 and 1:2:1 dopant content ratios show that endothermic peak occurs on their DTA curve,indicating crystal structure transformation such as phase transition or order-disorder transition.Also,thermo-gravimetric analysis(TGA)depending on temperature was evaluated in terms of mass loss.According to TGA curves,mass loss for both heating and cooling process can be negligible due to the small fluctuations(2%)on their TGA curves. | Ayhan Güldeste Mustafa Aldoori Murat Balci Mehmet Ari Yasin Polat | 2023 | Journal of Rare Earths2023，41，3： | 2 |
| 14 | The efficacy of muhiple-dose methotrexate treatment for unruptured tubal ectopic pregnancy and conversion rate to surgery:a study on 294 cases 显示文摘 | Balci O Ozdemir S Mahmoud AS | 2010 | Fertil Steril2010，93，7： | 1 |
| 15 | Effect of heating and acid pre-trement on pore size distribution of sepiolite显示文摘 | Balci S | 1999 | Clay Minerals1999，34，4： | 1 |
| 16 | Granulomatous hepatitis: MRI findings 显示文摘 | Balci NC Tunaci A Akinci A | 2001 | Magn Reson Imaging2001，19，8： | 1 |
| 17 | Investigation into the effects of different rocks on rock cuttability by a V-type disc cutter显示文摘 | C Balci D Tumac | 2012 | Tun- nelling and Underground Space Technology2012，，30： | 1 |
| 18 | Complex renal cysts:findings on MR imaging显示文摘 | Balci NC Semelka RC Patt RH | | 0，，06： | 1 |
| 19 | Plasma fibroblast growth factor-23 levels are independently associated with carotid artery atherosclerosis in maintenance hemodialysis patients显示文摘 | Balci M Kirkpantur A Gulbay M | 2010 | Hemodial Int2010，14，4： | 1 |
| 20 | Environmental impact of the marine aquaculture in Güllük Bay,Turkey显示文摘 | DEMIRAK A BALCI A TFEKCI M | 2006 | Environmental monitoring and assessment2006，123，1： | 1 |
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