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| 1 | 2012 Update: World Allergy Organization Guidelines for the assessment and management of anaphylaxis显示文摘 | F. Estelle R. Simons Ledit R.F. Ardusso M. Beatrice Bilò Vesselin Dimov Motohiro Ebisawa Yehia M. El-Gamal Dennis K. Ledford Richard F. Lockey Johannes Ring Mario Sanchez-Borges Gian Enrico Senna Aziz Sheikh Bernard Y. Thong Margitta Worm | 2012 | Current Opinion in Allergy and Clinical Immunology2012，，4： | 1 |
| 2 | Trends in the epidemiology of asthma in England:a national study of 333,294 patients 显示文摘 | Colin R Simpson Aziz Sheikh | 2010 | J R Soc Med2010，103，3： | 1 |
| 3 | A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis显示文摘 | Anthony J Avery Sarah Rodgers Judith A Cantrill Sarah Armstrong Kathrin Cresswell Martin Eden Rachel A Elliott Rachel Howard Denise Kendrick Caroline J Morris Robin J Prescott Glen Swanwick Matthew Franklin Koen Putman Matthew Boyd Aziz Sheikh | 2012 | The Lancet . 2012 (9823)2012，，： | 1 |
| 4 | Trend in the epidemiology of asthma in England:a national study of 333,294patients显示文摘 | Colin R Simpon Aziz Sheikh | 2010 | J R Soc Med2010，103，3： | 1 |
| 5 | World Allergy Organization anaphylaxis guidelines: Summary显示文摘 | F. Estelle R. Simons Ledit R.F. Ardusso M. Beatrice Bilò Yehia M. El-Gamal Dennis K. Ledford Johannes Ring Mario Sanchez-Borges Gian Enrico Senna Aziz Sheikh Bernard Y. Thong | 2011 | The Journal of Allergy and Clinical Immunology2011，，3： | 1 |
| 6 | World Allergy Organization Guidelines for the Assessment and Management of Anaphylaxis显示文摘 | F. Estelle R. Simons Ledit R. F. Ardusso M. Beatrice Bilò Yehia M. El-Gamal Dennis K. Ledford Johannes Ring Mario Sanchez-Borges Gian Enrico Senna Aziz Sheikh Bernard Y. Thong | 2011 | World Allergy Organization Journal2011，，： | 1 |
| 7 | 过敏反应显示文摘一位60岁的老人想要谈谈他最近被昆虫叮咬后的过敏反应,他出示了一封急诊室的信,上面写着:“被蜜蜂叮咬后的过敏反应,治疗之后要找全科医师随访。”应该考虑哪些问题 发生了,什么事?这是否是过敏反应?过敏反应这个词可能涉及急性的、潜在致命的系统过敏性功能紊乱,包括心血管系统和呼吸系统,或者两者皆有。 | Aziz Sheikh Samantha Walker 朱丽琳 | 2006 | 英国医学杂志中文版2006，9，4： | 0 |
| 8 | 转移到眼前房的转移性乳腺癌病例报道及讨论(英文)显示文摘Intraocular metastases are the most common malignancies of the eye.Carcinoma of the breast is the most common malignancy to metastasize to the uvea usually posterior uvea.Anterior chamber metastasis is extremely rare.We describe a patient of breast cancer who presented with pain and impaired vision in right eye 8.5 months after metastasis to bone and other viscera were detected and more than 10 years after her primary disease was diagnosed.Multiple yellowish white deposits were noted scattered in anterior chamber giving rise to symptoms of acute narrow angle glaucoma.Metastatic deposits of duct cell carcinoma cells were found by fine needle aspiration cytology.Patient received local external beam radiotherapy to right eye with moderate improvement in her symptoms.The rare features in this case were clinical presentation of acute glaucoma and anterior chamber as the site of metastasis. | Vimal Pandita Sheikh Aejaz Aziz Tariq Qureshi Jyoti Raina | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，8： | 0 |
| 9 | 过敏反应:急性发作及其他显示文摘本文要点 诊断基于临床表现——暴露于可能或已知变应原数分钟至数小时后,机体系统中有一个以上的特征性症状突然出现 严重或致命性过敏反应相关因素包括哮喘、心血管疾病、肥大细胞增多症和β阻滞剂等药物 当过敏反应发生时,立即呼叫援助,肌注肾上腺素,将患者置于平卧位或半卧位并抬高下肢 在发作期间,如果需要可给予高流量氧疗,建立静脉通道以提供大量液体,并实施心肺,复苏 为高危患者提供肾上腺素自动注射器、个体化过敏反应紧急行动方案以及医疗身份证 | F Estelle R Simons Aziz Sheikh 高晓方(译) 陈良安(校) | 2013 | 英国医学杂志中文版2013，16，5： | 0 |
| 10 | Anaphylaxis显示文摘A 60 year old man attends to discuss his recent allergic reaction to an insect sting. He presents you with the casualtyletter which reads: 'Treated for anaphylaxis after bee sting-see GP for follow-up.' | Aziz Sheikh Samantha Walker | 2006 | 英国医学杂志中文版2006，9，3： | 0 |
| 11 | 心包原发性滑膜肉瘤1例报道(英文)显示文摘Primary pericardial sarcomas are extremely rare. We report a case of 19 year old male who presented with cough, dyspnoea, and orthopnea. Investigations and exploratory thoracotomy revealed a large pericardial mass. Surgical debulking of the tumor was performed and the histopathological examination was compatible with synovial sarcoma. The tumor was unresectable due to its invasion and adhesion to mediastinal structures. Hence patient was started on palliative chemotherapy (adriamycin and ifosfamide based). Patient showed an initial symptomatic response but later on there was a clinical progres-sion and died within six months of his diagnosis. | Rangreze Imran Banday Manzoor Ahmad Sheikh Aejaz Aziz Bhat Salma Mohammad Latif Charoo | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，7： | 0 |
| 12 | Prenatal bisphenol A exposure impairs the aversive and spatial memory reduces the level of NMDA receptor subunits in the hippocampus of male Sprague Dawley rats显示文摘Memory impairment in children is an ongoing issue worldwide related to a learning disability. This neurobiological condition has been suggested to associate with bisphenol A (BPA) exposure during pregnancy. BPA is an inorganic compound used to produce polycarbonate plastics and epoxy resins. We conduct this study to investigate the effects of prenatal BPA exposure on the level of the N-methyl-D-aspartate (NMDA) receptor subunits, synaptic markers of the hippocampus and neurobehavioral outcomes in rats. The pregnant rats were given a daily dose of 5 mg/kg and 50 mg/kg of BPA with 0.5% Tween 80 orally from gestation day 2 until 21 (GD21). The level of GluN2A, GluN2B, PSD-95 and synapsin I in the hippocampus and its neurobehaviour outcomes were quantified and evaluated in the male foetus and adolescent rat. Prenatal BPA exposure reduced GluN2A, GluN2B, synapsin I and PSD-95 (Postsynaptic Density-95) in the male foetus and adolescent rat hippocampus compared to the control group. The prenatal BPA exposed rats demonstrated anxiety-related behaviour and impairment in aversive and spatial memory. The findings suggested that the impairment in neurobehavioral performance may inhibit the signalling pathway in the NMDA receptor subunits in the male foetus rat hippocampus leading to learning and memory deficits when reaching adolescence. | Norazirah Mat Nayan Andrean Husin Siti Hamimah Sheikh Abd Kadir Che Badariah Abd Aziz Musalmah Mazlan Rosfaiizah Siran | 2022 | Brain Science Advances2022，8，1： | 0 |
| 13 | 通过多视角定性访谈了解病人及看护人员的观点、体验以及需求显示文摘在定性研究中,与最常见的单一视角研究相比,通过对病人及专业和非专业看护人员进行关联访谈能够更多、更好地了解他们的需求和经验。二视角或三视角访谈,即把2个或3个(不同角色的)被访者作为一组或一个案例进行访谈,可以探讨复杂的互补视角和矛盾视角。这种方法在很多长期病患研究中有着很大的应用价值。 | Marilyn Kendall Scott A Murray Emma Carduff Allison Worth Fiona Harris Anna Lloyd Debbie Cavers Liz Grant Kirsty Boyd Aziz Sheikh 武弢(译) 武阳丰(校) | 2010 | 英国医学杂志中文版2010，13，2： | 0 |
| 14 | 卵巢移行细胞癌:一例报道与文献复习(英文)显示文摘Transitional cell carcinoma(TCC)of the ovary is a rare and recently recognized subtype of ovarian epithelial cancer.We presented the first case report from our Institute(Sheri Kashmir Instiute of Medical Sciences,Srinagar,India),which was initially misdiagnosed as stromal cell carcinoma(granulosa cell tumour),and on review of histopathology with immunohistochemistry,the diagnosis of TCC of the ovary was established.The aim of this article was to describe the typical case of primary TCC of the ovary and to review the literature for information on TCC management. | Sheikh Aijaz Aziz Abdul Rashid Lone Mohmad Hussain Mir Sumyra Khursheed Qadri Arif Nabi Bhat Farhana Siraj Bagdadi Mir Muzaffar Bashir Sanjeed Ahmed | 2013 | The Chinese-German Journal of Clinical Oncology2013，12，9： | 0 |
| 15 | 预测英格兰和威尔士2型糖尿病的发生风险:QD Score前瞻性推导和验证显示文摘目的 开发并验证一个新的糖尿病风险模型(QDScore),用来估计10年内获得糖尿病诊断的风险,该模型的基础建立于多样化的种族和社会经济地位人群。
设计 前瞻性开放性队列研究,使用的数据常规收集于355个英格兰和威尔士全科诊所,然后使用176个独立诊所的数据来验证这一评分。
参与者 该推导模型共包括2540753例患者,年龄25—79岁,产生16436315患者年,其中78081例为新诊断2型糖尿病;验证队列包括1232832例患者(7643037患者年),其中37535例患者为新发2型糖尿病。
结局评估指标 用Cox比例风险模型估计建立队列中风险因子的效应,并且在男性和女件中推导出一个风险公式。终模型中包括的检验预测变量有:自我报告的种族、年龄、性别、体重指数、吸烟状态、糖尿病家族史、Townsend剥夺评分、已接受治疗的高血压、心血管疾病和口前使用糖皮质激素;关注的结局评估指标是在全科诊所记录中新发生的糖尿病。校正和区分度的测定在验证队列中进行计算。
结果 不同种族间2型糖尿病的风险存在4到5倍的变异。与白人参照组相比,巴基斯坦女性的调整风险比为4.07(95%可信区间3.24~5.11),巴基斯坦男性为2.54(2.20~2.93)。巴基斯坦和盂加拉困男性与印度男性相对风险比显著增高。非洲黑人男性和中国女性与对应的白人参照组相比风险增加。在验证数据中,该模型解释了51.53%的女性差异(95%可信区间50.90~52.16)和48.16%的男性差异(47.52~48.80)。风险积分显示了良好的区分能力,女性中D值达2.11(95%可信区间2.08~2.14),男性中为1.97(1.95~2.00)。模型经过很好的校正。
结论 QDScore是第一个基于前瞻性队列研究并且包括了社会等级和种族来预测糖尿病10年风险的风险预测模型。该模型不需要实验室检查,并且可以应用于临床实践,另外,还可以通过一个简单的网络计算器为公众所用(www.qdscore.org)。 | Julia Hippisley-Cox Carol Coupland John Robson Aziz Sheikh Peter Brindle 曾静波(译) 李玉秀(校) | 2009 | 英国医学杂志中文版2009，12，5： | 0 |
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