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| 1 | 双谱指数对有症状的肝性脑病分级的敏感度和特异度:多中心、单盲、验证研究显示文摘 | Dahaba A A Worm H C 石虹 | 2008 | 肝脏2008，13，2： | 9 |
| 2 | 大堡礁和大峡谷世界遗产区的适应性管理显示文摘关于人类和环境相互关系的传统观念正在迅速改变。那种认为人类与自然是相互隔离的,自然资源是取之不尽用之不竭的,而且认为世界是稳定的、可以预测的并且是平衡的旧观点已经过时了。在动态的社会-生态景观中强调学习和灵活性管理为基础的适应性方法的新的理念框架已经迅速初现端倪。我们以两个典型的世界遗产地区(大堡礁和大峡谷)为案例来研究如何在自然资源管理中通过改善科学和社会两个方面的结合来指导多尺度管理系统的变革从而应对和处理人类越来越占据主导的世界中出现的不确定性、风险和变化。 | Terence P.Hughes Lance H.Gunderson Carl Folke Andrew H.Baird David Bellwood Fikret Berkes Beatrice Crona Ariella Helfgott Heather Leslie Jon Norberg Magnus Nystrm Per Olsson Henrik sterblom Marten Scheffer Heidi Schuttenberg Robert S.Steneck Maria Teng Max Troell Brian Walker James Wilson Boris Worm 丁莉 | 2007 | AMBIO-人类环境杂志2007，36，B11： | 4 |
| 3 | 代谢型谷氨酸受体可作为一种新型恶性胶质瘤治疗靶点(英文)显示文摘Objective Metabotropic glutamate receptors(mG luR)are predominantly involved in maintenance of cellular homeostasis of central nervous system.However,evidences have suggested other roles of mG luR in human tumors.Aberrant mG luR signaling has been shown to participate in transformation and maintenance of various cancer types,including malignant brain tumors.This review intends to summarize recent findings regarding the involvement of mG luR-mediated intracellular signaling pathways in progression,aggressiveness,and recurrence of malignant gliomas,mainly glioblastomas(GBM),highlighting the potential therapeutic applications of mG luR ligands.In addition to the growing number of studies reporting mG luR gene or protein expression in glioma samples(resections,lineages,and primary cultures),pharmacological blockade in vitro of mG luR1 and mG luR3 by selective ligands has been shown to be anti-proliferative and anti-migratory,decreasing activation of MAPK and PI3K pathways.In addition,mG luR3 antagonists promoted astroglial differentiation of GBM cells and also enabled cytotoxic action of temozolomide(TMZ).mG luR3-dependent TMZ toxicity was supported by increasing levels of MGMT transcripts through an intracellular signaling pathway that sequentially involves PI3K and NF-κB.Further,continuous pharmacological blockade of mG luR1 and mG luR3 have been shown to reduced growth of GBM tumor in two independent in vivo xenograft models.In parallel,low levels of mG luR3 mRNA in GBM resections may be a predictor for long survival rate of patients.Since several Phase I,II and III clinical trials are being performed using group I and II mG luR modulators,there is a strong scientifically-based rationale for testing mG luR antagonists as an adjuvant therapy for malignant brain tumors. | Pereira MS Klamt F Thomé CC Worm PV de Oliveira DL | 2017 | 中华神经外科疾病研究杂志2017，16，1： | 3 |
| 4 | Estimating bilateral exposures in the German interbank market: Is there a danger of contagion?显示文摘 | Christian Upper Andreas Worms | 2003 | European Economic Review2003，，4： | 3 |
| 5 | Risk factors for genital HPV DNA in men resemble those found in women:a study of male attendees at a Danish STD clinic 显示文摘 | Svare EI Kjaer SK Worm AM | 2002 | Sex Transm Infect2002，78，3： | 2 |
| 6 | Clinical lipoatrophy in HIV-1 patients on HAART is not associated with increased abdominal girth, hyperlipidaemia or glucose intolerance 显示文摘 | WORM D KIRK O ANDERSEN O | 2002 | HIV Med2002，3，4： | 1 |
| 7 | Predator diversity hotspots in the blue ocean显示文摘 | Worm B Lotze H K Myers R A | 2003 | Proceedings of the National Academy of Sci?ences2003，100，17： | 1 |
| 8 | Estimating bilateral exposures in the German interbank market:is there a danger of contagion显示文摘 | Upper Christian Worms Andreas | | 0，，02： | 1 |
| 9 | Generalized inverses of toeplitz matrix显示文摘 | Cline R E Plemmons R J Worm G | 1974 | Linear Algebra Appl1974，8，： | 1 |
| 10 | Aberrant P27 promoter methylation in malignant melanoma显示文摘 | Worm J Bartkova J Kirkin AF | 2000 | Oncngene2000，19，44： | 1 |
| 11 | Biodiversity, productivity and stability in real food webs 显示文摘 | Worm B Duffy J E | 2003 | Trends in Ecology & Evolution2003，18，12： | 1 |
| 12 | The agger nasi cell:the key to under-standing the anatomy of the frontal recess显示文摘 | Worm aid P J | 2011 | Otolaryngol Head Neck Surg2011，，129： | 1 |
| 13 | Decline of Pacific tuna populat- ions exaggerated显示文摘 | Myers R A Worm B | 2005 | Nature2005，434，： | 1 |
| 14 | Preconditioning prevents the inhibition of Na+, K+-ATPase activity after brain ischemia显示文摘 | de Souza Wyse AT Streck EL Worm P | 2000 | Neurochem Res2000，25，7： | 1 |
| 15 | The modified 2VO ischemia protocol causes cognitive impairment similar to that induced by the standard method,but with a better survival rate显示文摘 | Cechetti F Worm P V Pereira L O | 2010 | Braz J Med Biol Res2010，43，12： | 1 |
| 16 | Apocynin inhibits peroxynitrite formation by murine macrophages 显示文摘 | Muijsers R B R van Den Worm E Folkerts G | 2000 | British journal of pharmacology2000，130，4： | 1 |
| 17 | Healthy obesity Why the adiposity par adox is only seemingly paradox 显示文摘 | Strohle A Worm N | 2014 | Med Monatsschr Pharm2014，37，2： | 1 |
| 18 | Chronic brain hypoperfusion causes early glial activation and neuronal death,and subsequent long-term memory impairment 显示文摘 | Cechetti F Pagnussat A S Worm P V | 2012 | Brain Res Bull2012，87，1： | 1 |
| 19 | Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator显示文摘 | Juncker-Jensen A Lykkesfeldt AE Worm J | 2006 | Growth Horm IGF Res2006，16，： | 1 |
| 20 | Hyalinizing trabecular tumour of the thyroid - differential expression of distinct miRNAs compared with papillary thyroid carcinoma 显示文摘 | Sheu SY Vogel E Worm K | 2010 | Histopathology2010，56，5： | 1 |
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