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| 1 | Impact of a clinical pathway on treatment outcome in patients with acute pancreatitis显示文摘AIM:To determine the impact of a clinical pathway(CP) on acute pancreatitis(AP) treatment outcome.METHODS:A retrospective analysis of medical records was performed. We compared the results of AP treatment outcome over two time periods in our centre,before(2006-2007) and after(2010-2012) the implementation of a CP. The CP comprised the following indicators of quality:performance of all laboratory tests on admission(including lipids and carbohydrate deficient transferrin),determination of AP aetiology,abdomen ultrasound(US) within the first 24 h after admission,contrast-enhanced computed tomography of the abdomen in all cases of suspected pancreatic necrosis,appropriately selected and sufficiently used antibiotic therapy(if necessary),pain control,adequate hydration,control of haemodynamic parameters and transfer to the Intensive Care Unit(ICU)(if necessary),endoscopic retrograde cholangiopancreatography(ERCP) in biliary AP,surgical treatment(if necessary),and advice on outpatient follow-up after discharge. A comparison of the length of stay with that in other Slovenian hospitals was also performed.RESULTS:There were 139 patients treated in the three-year period after the introduction of a CP,of which 81(58.3%) were male and 58(41.7%) female. The patients' mean age was 59.6 ± 17.3 years. The most common aetiologies were alcoholism and gallstones(38.8% each),followed by unexplained(11.5%),drug-induced,hypertriglyceridemia,post ERCP(2.9% each) and tumours(2.2%). Antibiotic therapy was prescribed in 72(51.8%) patients. Abdominal US was performed in all patients within the first 24 h after admission. Thirty-two(23.0%) patients were treated in the ICU. Four patients died(2.9%). In comparison to 2006-2007,we found an increased number of alcoholic and biliary AP and an associateddecrease in the number of unexplained aetiology cases. The use of antibiotics also significantly decreased after the implementation of a CP(from 70.3% to 51.8%; P = 0.003). There was no statistically significant difference in mortality(1.8% vs 2.9%). The length of stay was significantly shorter when compared to the Slovenian average(P = 0.018).CONCLUSION:The introduction of a CP has improved the treatment of patients with AP,as assessed by all of the observed parameters. | Miroslav Vujasinovic Jana Makuc Bojan Tepes Apolon Marolt Zdenko Kikec Nace Robac | 2015 | World Journal of Gastroenterology2015，21，30： | 13 |
| 2 | Translating health status questionnaires and evaluating their quality:the IQOLA project approach显示文摘 | BULLINGER M ALONSO J APOLONE G | 1998 | Clin Epidemiol1998，51，11： | 1 |
| 3 | Factors associated with poor health-related quality of life of patients with cirrhosis显示文摘 | Giulio Marchesini Giampaolo Bianchi Piero Amodio Francesco Salerno Manuela Merli Carmine Panella Carmela Loguercio Giovanni Apolone Mauro Niero Roberto Abbiati The Italian Study Group for Quality of Life in Cirrhosis | 2001 | Gastroenterology2001，，1： | 1 |
| 4 | Measuring quality of life in dyspeptic patients: development and validation of a new specific health status questionnaire显示文摘 | Francesco Bamfi M.S Antonio Olivieri Fabio Arpinelli Gianfranco De Carli Giuseppe Recchia Lionello Gandolfi Lorenzo Norberto Franco Pacini Calogero Surrenti Sidney H Irvine Giovanni Apolone | 1999 | The American Journal of Gastroenterology1999，，3： | 1 |
| 5 | Effectiveness of ad- juvanted influenza vaccination in elderly subjects in north- ern Italy显示文摘 | Mannino S VilIa M Apolone G | 2012 | Am J Epidemiol2012，176，6： | 1 |
| 6 | Evaluation of the comparative analgesic effectiveness of transdermal and oral opioids in cancer patients: A propensity score analysis显示文摘 | Apolone G Deandrea S Montanari M | 2012 | Eur J Pain2012，16，2： | 1 |
| 7 | Evaluation of theEORTC QLQ-C 30 questionnaire: a comparison with SF- 36Health Survey in a cohort of Italian long-survival cancer patients显示文摘 | Apolone G Filiberti A Cifani S | 1998 | Ann Oncol1998，9，5： | 1 |
| 8 | Use of Structural Equation Modeling to Test the Construct Validity of the SF-36 Health Survey in Ten Countries显示文摘 | Susan D. Keller John E. Ware Peter M. Bentler Neil K. Aaronson Jordi Alonso Giovanni Apolone Jakob B. Bjorner John Brazier Monika Bullinger Stein Kaasa Alain Leplège Marianne Sullivan Barbara Gandek | 1998 | Journal of Clinical Epidemiology1998，，11： | 1 |
| 9 | Evaluation of the comparative analgesic effectiveness of transdermal and oral opioids in Cancer patients: a propensity score analysis 显示文摘 | Apolone G Deandrea S Montanari M | 2012 | Eur J Pain2012，16，2： | 1 |
| 10 | Evaluation of the comparative analgesic effectiveness of transdermal and oral opioids in cancer patients:a propensity score analysis显示文摘 | Apolone G Deandrea S Montanari M | | 0，，02： | 1 |
| 11 | Translating heatlth status questionnaires and evaluating their quality:the IQOLA project approach显示文摘 | BULLINGER M ALONSO J APOLONE G | 1998 | J Clin Epidemiol1998，51，11： | 1 |
| 12 | International quality of life assessment (IQOLA) project显示文摘 | N. K. Aaronson C. Acquadro J. Alonso G. Apolone D. Bucquet M. Bullinger K. Bungay S. Fukuhara B. Gandek S. Keller D. Razavi R. Sanson-Fisher M. Sullivan S. Wood-Dauphinee A. Wagner J. E. Ware | 1992 | Quality of Life Research1992，，5： | 1 |
| 13 | Review of the Concept of Quality of Life Assessment and Discussion of the Present Trend Iniclinical Research显示文摘 | Apolone G Mosconi P | 1998 | Nephrol Dial Transplant1998，13，1： | 1 |
| 14 | Expert conference on cancer pain assessment and classification-the need for international con- sensus: working proposals on international standards显示文摘 | Kaasa S Apolone G Klepstad P | 2011 | BMJ Sup- port Palliat Care2011，1，3： | 1 |
| 15 | Review of the concept of quality of life assenssment and discussion of the present trend iniclinical显示文摘 | Apolone G Mosconi P | 1998 | Research Nephrol Dial Transplant1998，13，1： | 1 |
| 16 | Endo- metrial Resection Versus Vaginal Hysterectomy for Menorrhagia : Long - terra Clinical and Quality- of- life Outcomes显示文摘 | Crosignani PG Vercellini P Apolone G | 1997 | Am J Obstet Gynecol1997，177，1： | 1 |
| 17 | Translating Health Status Questionnaires and Evaluating Their Quality: The IQOLA Project Approach显示文摘 | Bullinger M Alonso J Apolone G | 1998 | Journal of Clinical Epidemiol1998，51，11： | 1 |
| 18 | Evaluation of the EORTC QLQ- C30 questionnaire: A comparison with SF- 36 health sur- vey in a cohort of Italian long - survival cancer patients显示文摘 | Apolone G Fiiiberti A Cifani S | 1998 | An- nals of Oncology1998，9，5： | 1 |
| 19 | Evaluation of the comparative analgesic effectiveness of transdermal and oral opioids in cancer patients:a propensity score analysis显示文摘 | Apolone G Deandrea S Montanari M | 2012 | Eur J Pain2012，16，2： | 1 |
| 20 | International quality of life assessment (IQOLA) project显示文摘 | N. K. Aaronson C. Acquadro J. Alonso G. Apolone D. Bucquet M. Bullinger K. Bungay S. Fukuhara B. Gandek S. Keller D. Razavi R. Sanson-Fisher M. Sullivan S. Wood-Dauphinee A. Wagner J. E. Ware | 1992 | Quality of Life Research1992，，5： | 1 |
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