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| 1 | Fibroadhesive scarring of grafted collagen scaffolds interferes with implant–host neural tissue integration and bridging in experimental spinal cord injury显示文摘Severe traumatic spinal cord injury(SCI)results in a devastating and permanent loss of function,and is currently an incurable condition.It is generally accepted that future intervention strategies will require combinational approaches,including bioengineered scaffolds,to support axon growth across tissue scarring and cystic cavitation.Previously,we demonstrated that implantation of a microporous type-I collagen scaffold into an experimental model of SCI was capable of supporting functional recovery in the absence of extensive implant–host neural tissue integration.Here,we demonstrate the reactive host cellular responses that may be detrimental to neural tissue integration after implantation of collagen scaffolds into unilateral resection injuries of the adult rat spinal cord.Immunohistochemistry demonstrated scattered fibroblast-like cell infiltration throughout the scaffolds as well as the presence of variable layers of densely packed cells,the fine processes of which extended along the graft–host interface.Few reactive astroglial or regenerating axonal profiles could be seen traversing this layer.Such encapsulation-type behaviour around bioengineered scaffolds impedes the integration of host neural tissues and reduces the intended bridging role of the implant.Characterization of the cellular and molecular mechanisms underpinning this behaviour will be pivotal in the future design of collagen-based bridging scaffolds intended for regenerative medicine. | Haktan Altinova Sebastian Hammes Moniek Palm Jose Gerardo-Nava Pascal Achenbach Ronald Deumens Emmanuel Hermans Tobias Fuhrmann Arne Boecker Sabien Geraldine Antonia van Neerven Ahmet Bozkurt Joachim Weis Gary Anthony Brook | 2019 | Regenerative Biomaterials2019，6，2： | 4 |
| 2 | 云成本分析显示文摘云计算已经成为现今互联网发展的主题,其延伸和发展出的云存储也当仁不让地成为了主流的数据存储和管理方式。那么,经营一个云端的成本和收益到底如何呢?文中将以Backblaze等公司的云成本和收益情况进行分析。 | Sebastian Anthony | 2012 | 物联网技术2012，2，10： | 3 |
| 3 | Ciliated hepatic foregut cyst:an increasingly diagnosed condition显示文摘BACKGROUND:Ciliated foregut cysts of the liver are rare, with only 96 cases diagnosed since the first description in 1857.They are being increasingly diagnosed recently;the majority of the cases have been reported in the last 15 years. Although they bear a close resemblance to the simple cyst of the liver which has essentially a benign course,ciliated hepatic foregut cysts(CHFCs)can progress to malignancy with devastating consequences.It is imperative that this group of conditions be diagnosed and treated adequately. DATA SOURCES:This review includes discussion of the data from all the 96 reported cases from English and non-English literature.Analysis of the incidence rates, embryogenesis,growth,clinical features,risk of malignancy and the prognosis are highlighted systematically.The roles of various diagnostic modalities including ultrasound, CT,MRI,fine needle aspiration cytology(FNAC), immunohistochemistry and surgery are further discussed. RESULTS:The mean age of patients with CHFC was 48± 12 years.The male/female ratio was 1.1∶1.The majority of patients with CHFC(62%)were asymptomatic,and the common mode of presentation was right upper abdominal pain.The cysts occurred in the left lobe in 51 patients, with sole location in segmentⅣin 44,and in the right lobe in 26.The average size of the cysts was 3.6±2.12 cm. The majority of the cysts were unilocular,and only 7 cases were multilocular.Cyst contents were described as viscous or mucinous in 73 patients,whereas bilious fluid was noted in 3.Large cysts having squamous carcinoma were cited in 3 patients,and 2 had extensive squamous metaplasia without malignancy.Others had benign histopathology. CONCLUSIONS:Clinicians have become increasingly aware of CHFC.Imaging alone is not diagnostic per se, but when considered in the context of the global picture does provide important clues to the diagnosis.FNAC is diagnostic by the presence of the ciliated columnar aspirate but lacks sensitivity.Infantile presentation is usually accompanied by biliary communication and mandates a different surgical approach.The demonstration of malignant transformation in 3 cases and its fatal course emphasizes the need for surgical resection in all cases once the diagnosis is made. | Sharad Sharma Amanda G.Dean Ayumi Corn Vivek Kohli Harlan I Wright Anthony Sebastian Nicolas Jabbour | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，6： | 2 |
| 4 | Ciliated Hepatic Foregut Cyst: An Increasingly Diagnosed Condition显示文摘 | Sharad Sharma Ayumi Corn Vivek Kohli Harlan I. Wright Anthony Sebastian Nicolas Jabbour | 2008 | Digestive Diseases and Sciences2008，，10： | 1 |
| 5 | Management of biliary stricture guided by the Spyglass Direct Visualization System in a liver transplant recipient: an innovative approach显示文摘 | Harlan Wright Sharad Sharma Ahmet Gurakar Anthony Sebastian Vivek Kohli Nicolas Jabbour | 2008 | Gastrointestinal Endoscopy2008，，7： | 1 |
| 6 | Endovascular treatment of hepatic artery thrombosis following liver transplantation显示文摘 | Ashish Singhal Kenneth Stokes Anthony Sebastian Harlan I Wright Vivek Kohli | 2010 | Transplant International2010，，3： | 1 |
| 7 | Salt Sensitivity in Blacks: Evidence That the Initial Pressor Effect of NaCl Involves Inhibition of Vasodilatation by Asymmetrical Dimethylarginine显示文摘 | Olga Schmidlin Alex Forman Anna Leone Anthony Sebastian R. Curtis Morris | 2011 | Hypertension2011，，3： | 1 |
| 8 | SAFE USE OF HEPATIC ALLOGRAFTS FROM DONORS OLDER THAN 70 YEARS1显示文摘 | Sukru Emre Myron E. Schwartz Gulum Altaca Paul Sethi M. Isabel Fiel Stephen R. Guy Dympna M. Kelly Anthony Sebastian Adrian Fisher Denise Eickmeyer Patricia A. Sheiner Charles M. Miller | 1996 | Transplantation1996，，1： | 1 |
| 9 | Gender, work-family responsibilities, and sleep 显示文摘 | MAUME D J SEBASTIAN R A ANTHONY R B | 2010 | Gender and Society2010，24，6： | 1 |
| 10 | Assessing Relative Risks of Infection and Rejection: A Meta-analysis using an Immune Function Assay显示文摘 | Richard J. Kowalski Diane R. Post Roslyn B. Mannon Anthony Sebastian Harlan I. Wright Gary Sigle James Burdick Kareem Abu Elmagd Adriana Zeevi Mayra Lopez-Cepero John A. Daller H Albin Gritsch Elaine F. Reed Johann Jonsson Douglas Hawkins Judith A. Britz | 2006 | Transplantation2006，，5： | 1 |
| 11 | Calcineurin Inhibitor–Free Mycophenolate Mofetil/Sirolimus Maintenance in Liver Transplantation: The Randomized Spare‐the‐Nephron Trial显示文摘 | Lewis Teperman Dilip Moonka Anthony Sebastian Linda Sher Paul Marotta Christopher Marsh Baburao Koneru John Goss Dennis Preston John P. Roberts | 2013 | Liver Transpl2013，，7： | 1 |
| 12 | 成于胶片,败于数码——柯达百年沉浮史显示文摘柯达公司的发展历程漫长而曲折。回顾其百年历史,其中值得—提的亮点颇多:第一卷相机胶卷、第一台面向大众市场的照相机、第一张35毫米彩色胶片、第一个百万像素级数字传感器……虽然现在柯达已经风光不再,但我们仍无法否认它对大众文化几乎无所不在的影响。 | Sebastian Anthony 陈继龙 | 2012 | 新东方英语(中英文版)2012，，6： | 0 |
| 13 | 2017年温布尔登网球锦标赛的黑科技显示文摘温布尔登锦标赛每年消耗掉大约28吨草莓、10000升奶油以及32000杯飘仙(Pimm)饮料,以追求无上的奢侈快乐著称。尽管大多数公司、组织和机构都在力求削减成本,温布尔登锦标赛却恪守口号:"不求便宜,但求更好"。 | Sebastian Anthony 沈建苗 | 2017 | IT经理世界2017，0，22： | 0 |
| 14 | 云到底有多大?显示文摘计算机的云计算已经成为现今互联网发展的主题,其延伸和发展出的云存储也当仁不让地成为了主流的数据存储和管理方式。那么,这些云到底有多大呢?文章通过几个大公司的数据对其数据规模和带宽进行了估计。 | Sebastian Anthony | 2012 | 物联网技术2012，2，9： | 0 |
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