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| 1 | 元谋古猿下颌臼齿三维立体特征显示文摘采用欧氏距离矩阵分析 (EDMA)方法对 72枚元谋古猿及作为对比样本的 10枚禄丰古猿、现生大猿类和人类下颌臼齿齿冠 13个测量标志点三维测量数据的统计分析显示 :元谋古猿在下颌臼齿齿冠三维形态测量特征上与禄丰古猿最为接近。与现生大猿类及人类相比 ,元谋古猿和禄丰古猿均与人类之间呈现出非常显著的差异 ,而与猿类较为接近。它们两者及现生大猿类均与人类之间具有许多共同的差异表现特点。元谋古猿在下颌臼齿三维测量特征方面与三种现生大猿类各自之间的差别表现相似。其中 ,元谋古猿与猩猩之间在牙齿形态特征上似乎更为接近。 | 刘武 郑良 Alan Walker | 2001 | 人类学学报2001,20,3: | 8 |
| 2 | Cardiovascular Function and Treatment in β-Thalassemia Major: A Consensus Statement From the American Heart Association显示文摘 | Dudley J. Pennell James E. Udelson Andrew E. Arai Biykem Bozkurt Alan R. Cohen Renzo Galanello Timothy M. Hoffman Michael S. Kiernan Stamatios Lerakis Antonio Piga John B. Porter John Malcolm Walker John Wood | 2013 | Circulation2013,,3: | 3 |
| 3 | Genetic mapping and survey of powdery mildew resistance in the wild Central Asian ancestor of cultivated grapevines in Central Asia显示文摘Cultivated grapevines(Vitis vinifera)lack resistance to powdery mildew(PM)with few exceptions.Resistance to this pathogen within V.vinifera has been reported in earlier studies and identified as the Ren1 locus in two Central Asian table grape accessions.Other PM-resistant cultivated varieties and accessions of the wild ancestor V.vinifera subsp.sylvestris were soon identified raising questions regarding the origin of the resistance.In this study,F1 breeding populations were developed with a PM susceptible V.vinifera subsp.vinifera breeding line and a PM-resistant subsp.sylvestris accession.Genotyping was carried out with five Ren1 locus linked SSR markers.A PM resistance locus explaining up to 96%of the phenotypic variation was identified in the same genomic position,where the Ren1 locus was previously reported.New SSR marker alleles linked with the resistance locus were identified.We report results of PM resistance in multiple accessions of subsp.sylvestris collected as seed lots or cuttings from five countries in the Caucasus and Central Asia.A total of 20 females from 11 seed lots and 19 males from nine seed lots collected from Georgia,Armenia,and Azerbaijan were resistant to PM.Three male and one female plant collected as cuttings from Afghanistan and Iran were also resistant to PM.Allelic analysis of markers linked with the Ren1 locus in conjunction with disease evaluation data found a high diversity of allelic haplotypes,which are only possible via recombination events occurring over a long time period.Sequence analysis of two alleles of the SSR marker that cosegregates with the resistance found SNPs that were present in the wild progenitor and in cultivated forms.Variable levels of PM resistance among the tested accessions were also observed.These lines of evidence suggest that the powdery mildew fungus may have been present in Asia for a longer time than currently thought,giving the wild progenitor V.vinifera subsp.sylvestris time to coevolve with and develop resistance to this pathogen. | Summaira Riaz Cristina M.Menéndez Alan Tenscher Daniel Pap M.Andrew Walker | 2020 | Horticulture Research2020,7,1: | 2 |
| 4 | Three-dimensional Morphometric Analyses of Hominoid Lower Molars from Yuanmou in Yunnan Province,China显示文摘Analysis of 3D measurements of 13 landmarks on 72 Yuanmou Hominoid lower molars and some comparative samples, using Euclidean Distance Matrix Analysis (EDMA), show that the 3D morphometric features of Yuanmou Homi noid lower molars largely resemble those of Lufengpithecus. Compared with extant great apes and humans, both Yuanmou Hominoid and Lufengpithecus differ markedly from humans, whereas they show much resemblance to apes. The two Chinese hominoids and extant great apes are different from humans in many of the same ways. Moreover, 3D morphometric features of Yuanmou Hominoid lower molars differ from those of each of the three extant great apes in similar ways. Of the three, the orangutan is the closest match to Yuanmou Hominoid in tooth morphology. However, the exact implications of these similarities and differences remain to be determined. | Alan Walker | 2002 | 人类学学报2002,21,S1: | 2 |
| 5 | The Social Quality Approach : Bridg- ing Asia and Europe 显示文摘 | Alan Walker | 2009 | Development and Society2009,,2: | 1 |
| 6 | The re lease of coal nitrogen and sulfur on pyrolysis and partial gasifica tion in fluidized bed显示文摘 | Stephen P Middleton John W Patrick Alan Walker | 1997 | Fuel1997,76,13: | 1 |
| 7 | Non-ulcer Dyspepsia and Duodenal Eosinophilia: An Adult Endoscopic Population-Based Case-Control Study显示文摘 | Nicholas J. Talley Marjorie M. Walker Pertti Aro Jukka Ronkainen Tom Storskrubb Laura A. Hindley W. Scott Harmsen Alan R. Zinsmeister Lars Agréus | 2007 | Clinical Gastroenterology and Hepatology2007,,: | 1 |
| 8 | The formation of pyrophorie iron sulphide from rust 显示文摘 | Robert Walker Alan D Steele David T B Morgan | 1987 | Sur- face and Coatings Technology1987,31,: | 1 |
| 9 | A Phase I Study of FOLFIRINOX Plus IPI-926, a Hedgehog Pathway Inhibitor, for Advanced Pancreatic Adenocarcinoma显示文摘 | Andrew H. Ko Noelle LoConte Margaret A. Tempero Evan J. Walker R. Kate Kelley Stephanie Lewis Wei-Chou Chang Emily Kantoff Michael W. Vannier Daniel V. Catenacci Alan P. Venook Hedy L. Kindler | 2016 | Pancreas2016,,3: | 1 |
| 10 | Neoadjuvant Treatment for Resectable Cancer of the Esophagus and the Gastroesophageal Junction: A Meta-Analysis of Randomized Clinical Trials显示文摘 | Ioannis G. Kaklamanos MD PhD Gail R. Walker PhD Kristian Ferry MD Dido Franceschi MD Alan S. Livingstone MD | 2003 | Annals of Surgical Oncology2003,,7: | 1 |
| 11 | Effect of Red Clover Isoflavones on Cox -2 Activity in Murine and Human Monocyte/Macrophage Cells显示文摘 | Anna N C Lam Maryanne Demasi Michael J James Alan J Husband Catherine Walker | 2004 | NUTRITION AND CANCER2004,49,1: | 1 |
| 12 | Processing and properties of discontinuous reinforced aluminum composites显示文摘 | GEIGER ALAN L WALKER J A | 1991 | JOM1991,43,8: | 1 |
| 13 | Phylogeny, culturing, and metagenomics of the human gut microbiota显示文摘 | Alan W. Walker Sylvia H. Duncan Petra Louis Harry J. Flint | 2014 | Trends in Microbiology2014,,: | 1 |
| 14 | Neoadjuvant Treatment for Resectable Cancer of the Esophagus and the Gastroesophageal Junction: A Meta-Analysis of Randomized Clinical Trials显示文摘 | Ioannis G. Kaklamanos MD PhD Gail R. Walker PhD Kristian Ferry MD Dido Franceschi MD Alan S. Livingstone MD | 2003 | Annals of Surgical Oncology2003,,7: | 1 |
| 15 | Ice restructuring inhibition activities in antifreeze proteins with distinct differences in thermal hysteresis显示文摘 | Sally O. Yu Alan Brown Adam J. Middleton Melanie M. Tomczak Virginia K. Walker Peter L. Davies | 2010 | Cryobiology2010,,3: | 1 |
| 16 | Peter Townsend (1928–2009)显示文摘 | ALAN WALKER | 2009 | Ageing and Society2009,,7: | 1 |
| 17 | Controlling human platelet activation with calcium-binding nanoparticles显示文摘Human platelets aggregate at sites of blood vessel damage in response to a rise in their cytosolic calcium concentration.Controlling these cytosolic calcium rises would provide a method to inhibit platelet activation and prevent the unwanted blood clots that causes heart attack and strokes.Previously we have predicted that calcium accumulation within the lumen of an infolded portion of the platelet plasma membrane called the open canalicular system(OCS)is essential for maintaining this cytosolic calcium rise.Due to its nanometer dimensions of the OCS,it has been difficult to measure or interfere with the predicted luminal calcium accumulation.Here we utilise iron oxide magnetic nanoparticles coated with the known calcium chelator,citrate,to create calcium-binding nanoparticles.These were used to assess whether an OCS calcium store plays a role in controlling the dynamics of human platelet activation and aggregation.We demonstrate that citrate-coated nanoparticles are rapidly and selectively uptaken into the OCS of activated human platelets,where they act to buffer the accumulation of calcium there.Treatment with these calcium-binding nanoparticles reduced thrombin-evoked cytosolic calcium rises,and slowed platelet aggregation and clot retraction in human platelets.In contrast,nanoparticles that cannot bind calcium have no effect.This study demonstrates that the OCS acts as a key source of calcium for maintaining cytosolic calcium rises and accelerating platelet aggregation,and that calcium-binding nanoparticles targeted to the OCS could provide an anti-platelet therapy to treat patients at risk of suffering heart attacks or strokes. | David Cabrera Karen Walker Sandhya Moise Neil D.Telling Alan G.S.Harper | 2020 | Nano Research2020,13,10: | 1 |
| 18 | The for- mation of pyrophoric iron sulphide from rust 显示文摘 | Robert Walker Alan D Steele David T B Morgan | 1987 | Surface and Coatings Technology1987,31,: | 1 |
| 19 | Pyro- phoric oxidation of iron sulphide显示文摘 | Robert Walker Alan D Steele David T B Morgan | 1988 | Surface and Coatings Technology1988,34,: | 1 |
| 20 | A Longitudinal Examination of Concomitant Changes in Team Leadership and Customer Satisfaction显示文摘 | Walker Alan G James W Smither David A Waldman | 2008 | Personnel Psychology2008,61,3: | 1 |