|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Obesity: modern man's fertility nemesis显示文摘肥胖流行成长了到有关最近的年里,不是仅仅在西方的世界上的比例,但是在也开发国家。在男富饶和肥沃的相应减少可以向肥胖在平行被解释,并且肥胖应该被看作男富饶的病原学。研究证明肥胖由减少精液质量贡献不孕,改变精子 proteomes,贡献可勃起的机能障碍,并且导致与肥胖有关的另外的物理问题。为在男不孕上解释肥胖的效果的机制包括睡觉呼吸暂停和增加的阴囊的温度包括反常繁殖荷尔蒙层次,与肥胖联系的脂肪质导出荷尔蒙和 adipokines 的一个增加的版本,和另外的物理问题。最近,为肥胖相关的不孕的基因因素和标记被发现了并且可以解释肥沃的肥胖、不肥沃的肥胖的人之间的差别。处理为与肥胖有关的不孕是可得到的不仅,而且作为为从肥胖产生的另外的 comorbidities 的一个处理。自然重量损失,以及 bariatric 外科是为肥胖的病人的选择并且在恢复富饶和正常神经质的侧面显示出有希望的结果。脂肪质导出荷尔蒙的治疗学的干预包括 aromatase 禁止者,外长的睾丸激素代替治疗和维护和规定,特别地 leptin,可能也能在肥胖的男性恢复富饶。因为在这个区域的研究的相对不知道和缺乏,控制了研究应该被承担,更多的焦点应该作为男不孕的 etiolgy 被给肥胖。 | Stephanie Cabler Ashok Agarwal Margot Flint Stefan S. Du Plessis | 2010 | Asian Journal of Andrology2010，12，4： | 14 |
| 2 | Combination Therapy With Infliximab and Azathioprine Is Superior to Monotherapy With Either Agent in Ulcerative Colitis显示文摘 | Remo Panaccione Subrata Ghosh Stephen Middleton Juan R. Márquez Boyd B. Scott Laurence Flint Hubert JF. van Hoogstraten Annie C. Chen Hanzhe Zheng Silvio Danese Paul Rutgeerts | 2013 | Gastroenterology2013，，： | 5 |
| 3 | 青少年肥胖趋势及体质量指数与血压的相关性:健康青少年714922人的横断面研究显示文摘美国青年人中肥胖者占17%。肥胖与高血压患病率有很大关系。过去的研究样本量小,而且研究结果相互矛盾。该研究的目的是分析1998—2011年间青少年肥胖的趋势,并评估这些健康青少年的血压和体质量指数(body mass index,BMI)之间的关系。 | Chorin E Hassidim A Hartal M Havakuk O Flint N ZivBaran T Arbel Y 陈云 叶鹏 | 2016 | 中华高血压杂志2016，24，3： | 2 |
| 4 | Downscaling future climate scenarios to fine scales for hydrologic and ecological modeling and analysis显示文摘Introduction:Evaluating the environmental impacts of climate change on water resources and biological components of the landscape is an integral part of hydrologic and ecological investigations,and the resultant land and resource management in the twenty-first century.Impacts of both climate and simulated hydrologic parameters on ecological processes are relevant at scales that reflect the heterogeneity and complexity of landscapes.At present,simulations of climate change available from global climate models[GCMs]require downscaling for hydrologic or ecological applications.Methods:Using statistically downscaled future climate projections developed using constructed analogues,a methodology was developed to further downscale the projections spatially using a gradient-inverse-distancesquared approach for application to hydrologic modeling at 270-m spatial resolution.Results:This paper illustrates a methodology to downscale and bias-correct national GCMs to subkilometer scales that are applicable to fine-scale environmental processes.Four scenarios were chosen to bracket the range of future emissions put forth by the Intergovernmental Panel on Climate Change.Fine-scale applications of downscaled datasets of ecological and hydrologic correlations to variation in climate are illustrated.Conclusions:The methodology,which includes a sequence of rigorous analyses and calculations,is intended to reduce the addition of uncertainty to the climate data as a result of the downscaling while providing the fine-scale climate information necessary for ecological analyses.It results in new but consistent data sets for the US at 4 km,the southwest US at 270 m,and California at 90 m and illustrates the utility of fine-scale downscaling to analyses of ecological processes influenced by topographic complexity. | Lorraine E Flint Alan L Flint | 2012 | Ecological Processes2012，1，1： | 2 |
| 5 | Infliximab, Azathioprine, or Infliximab + Azathioprine for Treatment of Moderate to Severe Ulcerative Colitis: The UC Success Trial显示文摘 | Remo Panccione Subrata Ghosh Stephen Middleton Juan R. Marquez Igor Khalif Laurence Flint Hubert van Hoogstraten Hanzhe Zheng Silvio Danese Paul J. Rutgeerts | 2011 | Gastroenterology2011，，5： | 2 |
| 6 | Stimulatory and cytotoxic effects of an antiserum to adipocyte plasma membrane on adipose tissue metabolism in vitro and in vivo显示文摘 | Flint D J | 1986 | Int J Obe1986，10，： | 2 |
| 7 | Evolution in the Management of Hepatic Trauma: A 25-Year Perspective显示文摘 | J. David Richardson Glen A. Franklin James K. Lukan Eddy H. Carrillo David A. Spain Frank B. Miller Mark A. Wilson Hiram C. Polk Lewis M. Flint | 2000 | Annals of Surgery2000，，3： | 2 |
| 8 | Biotin synthase from Escherichia coli,an investigation of the low molecular weight and protein components required for activity in Vitro显示文摘 | Sanyal L Lee S L Flint D H | 1994 | J Am Chem Soc1994，116，： | 1 |
| 9 | The use of subtelomeric probes to study mental retardation 显示文摘 | Knight SJ Flint J | 2004 | Methods Cell Biol2004，75，： | 1 |
| 10 | Functional analysis of cell surface-expressed hepatitis C virus E2 glycoprotein显示文摘 | Flint M Thomas J M Maidens C M | 1999 | J Virol1999，73，8： | 1 |
| 11 | The detection of subtelomeric chromosomal rearrangements in idiopathic mental retardation 显示文摘 | Flint J Wilike AO Buckle VJ Winter RM Holland AJ McDermid HE | 1995 | Nat Genet1995，9，2： | 1 |
| 12 | Regulation of insulin receptors by prolactin in lactating rat mammary gland显示文摘 | | 1982 | Endo Jrinol1982，93，： | 1 |
| 13 | Functional characterization of intracellular and secreted forms of a truncated hepatitis C virus E2 glycoprotein显示文摘 | Dubuisson J Maidens C | 2000 | J Virol2000，74，： | 1 |
| 14 | The injured colon : relationships of management to complication显示文摘 | Flint LM Vitale GC Richardson JD | 1981 | Ann Surg1981，193，： | 1 |
| 15 | Ecosystem UV-B experiments in terrestrial communities: a review of recent findings and methodologies 显示文摘 | Flint S D Ryel R J Caldwell M M | 2003 | Agricultural and Forest Meteorology2003，120，1： | 1 |
| 16 | Depositional architec- ture and sequence stratigraphy of the Karoo basin floor to shelf edge succession, Laingsburg depocentre, South Africa显示文摘 | Flint S S Hodgson D M Sprague A R | 2010 | Marine and Pe- troleum Geology2010，27，1： | 1 |
| 17 | Exploring the phenomenon of customers, desired value change in a business-to-business context显示文摘 | Flint D J Woodruff R B and Gardial S F | 2002 | Journal of Marketing2002，66，10： | 1 |
| 18 | Crystal structure of human protein tyrosine phosphatase 1b显示文摘 | Barford D Flint A J Tonks N K | 1994 | Science1994，263，： | 1 |
| 19 | Control of mammary involution by insulin-like growth factor binding proteins:Role of prolactin显示文摘 | Flint D J Tonner E Knight C H | 2001 | Livestock Production Science2001，70，： | 1 |
| 20 | Lactate utilizing bacteria,isolated from human faeces,that produce butyrate as a major fermentation product显示文摘 | Duncan S H Louis P Flint H J | 2004 | Appl Environ Microbiol2004，70，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员