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| 1 | Safety of endovascular therapy for symptomatic intracranial artery stenosis:a national prospective registry显示文摘Introduction The safety outcomes of endovascular therapy for intracranial artery stenosis in a real-world stetting are largely unknown.The Clinical Registration Trial of Intracranial Stenting for Patients with Symptomatic Intracranial Artery Stenosis(CRTICAS)was a prospective,multicentre,real-world registry designed to assess these outcomes and the impact of centre experience.Methods 1140 severe,symptomatic intracranial arterial stenosis(ICAS)patients treated with endovascular therapy were included from 26 centres,further divided into three groups according to the annual centre volume of intracranial angioplasty and stent placement procedures over 2 years:(1)high volume for≥25 cases/year;(2)moderate volume for 10–25 cases/year and(3)low volume for<10 cases/year.Results The rate of 30-day stroke,transient ischaemic attack or death was 9.7%(111),with 5.4%,21.1%and 9.7%in high-volume,moderate-volume and low-volume centres,respectively(p<0.05).Multivariable logistic regression confirmed high-volume centres had a significantly lower primary endpoint compared with moderate-volume centres(OR=0.187,95%CI:0.056 to 0.627;p≤0.0001),while moderate-volume and low-volume centres showed no significant difference(p=0.8456).Conclusion Compared with the preceding randomised controlled trials,this real-world,prospective,multicentre registry shows a lower complication rate of endovascular treatment for symptomatic ICAS.Non-uniform utilisation in endovascular technology,institutional experience and patient selection in different volumes of centres may have an impact on overall safety of this treatment. | Yabing Wang Tao Wang Adam Andrew Dmytriw Kun Yang Liqun Jiao Huaizhang Shi Jie Lu Tianxiao Li Yujie Huang Zhenwei Zhao Wei Wu Jieqing Wan Qinjian Sun Bo Hong Yongli Li Liyong Zhang Jianfeng Chu Qiong Cheng Yiling Cai Pengfei Wang Qi Luo Hua Yang Baijing Dong Yang Zhang Jun Zhao Zuoquan Chen Wei Li Xiaoxin Bai Weiwen He Xueli Cai Maimai Ti Osama O Zaidat | 2022 | Stroke & Vascular Neurology2022,7,2: | 3 |
| 2 | Post-operative prevention and monitoring of Crohn’s disease recurrence显示文摘Crohn’s disease(CD)and ulcerative colitis(UC)are relapsing and remitting chronic inflammatory diseases of the gastrointestinal tract.Although surgery for UC can provide a cure,surgery for CD is rarely curative.In the past few decades,research has identified risk factors for postsurgical CD recurrence,enabling patient risk stratification to guide monitoring and prophylactic treatment to prevent CD recurrence.A MEDLINE literature review identified articles regarding post-operative monitoring of CD recurrence after resection surgery.In this review,we discuss the evidence on risk factors for postoperative CD recurrence as well as suggestions on post-operative management. | Kate E.Lee Sarah Cantrell Bo Shen Adam S.Faye | 2022 | Gastroenterology Report2022,10,1: | 3 |
| 3 | YAP1对颗粒细胞的重编程可导致具间质谱系和浆液性特征的高级别卵巢癌显示文摘高级别浆液性卵巢癌(HGSC)是临床中最常见、且恶性程度最高的卵巢癌.深入了解高级别浆液性卵巢癌的起源细胞可对该亚型卵巢癌进行有效预防和早期诊断.最近TCGA和AOCS通过分子分型研究发现了一种具有间充质特征的高级别浆液性卵巢癌亚型,并且表明该亚型是所有新发现的亚型中预后最差的一种,而且目前大家对于这种卵巢癌新亚型的起源细胞一无所知.在研究Hippo信号通路在卵巢颗粒细胞生理和病理中的作用时,意外地发现Hippo信号传导途径的主要效应分子YAP1的高度激活可以诱导具有间质谱系和高可塑性的卵巢颗粒细胞的去分化与重编程,最终导致具有浆液性特征的高级别卵巢癌的发生.本文的研究结果揭示了具间质特征的高级别浆液性卵巢癌的一种潜在起源细胞. | 吕向民 何春波 黄聪 滑国华 陈骍程 Barbara K.Timm Victoria M.Maclin Abigail A.Haggerty Shelly K.Aust Denae M.Golden Bhavana J.Dave Yun-An Tseng 陈利 王洪波 陈培超 David L.Klinkebiel Adam R.Karpf Jixin Dong Ronny I.Drapkin Bo R.Rueda John S.Davis 王诚 | 2020 | Science Bulletin2020,65,15: | 2 |
| 4 | Mineralogical and geochemical constraints on environmental impacts from waste rock at Taojiang Mn-ore deposit, central Hunan, China显示文摘 | Bo Peng Adam Piestrzynski Jadwiga Pieczonka Meilian Xiao Yaozhu Wang Shurong Xie Xiaoyan Tang Changxun Yu Zhi Song | 2007 | Environmental Geology2007,,7: | 2 |
| 5 | Isolation and Molecular Characterization of Toxoplasma gondii from Chickens in China显示文摘One strain of Toxoplasma gondii was successfully isolated from chickens in China by bioassay in mice. Antibodies and circulating antigens of T. gondii were assayed by the ELISA kits in 100 free range chickens from a rural area surrounding Funing, China. Fifty-three chickens were antibody-positive and 21 chickens were antigen positive. Hearts, brains, spleens, lungs, livers, and kidneys of 21 antibody or antigen-positive chickens were bioassayed in mice. One strain of T. gondii was isolated from 1 of 21 (4.76%) chickens. The isolated T. gondii killed all of the inoculated mice. Genotyping of this isolate using polymorphisms at the loci 5′-SAG2, 3′-SAG2, SAG3, cB21-4, L358, BTUB, and GRA6 revealed that it was Type I. These indicated that it was virulent for mice. This is the first report of isolation of T. gondii from chickens in China. | ZHAO Guang-wei SHEN Bo XIE Qing XU Li-xin YAN Ruo-feng SONG Xiao-kai Hassan Ibrahim Adam LI Xiang-rui | 2012 | Journal of Integrative Agriculture2012,11,8: | 2 |
| 6 | Ovarian superstimulatory response relative to follicular wave emergence in heifers显示文摘 | Nasser L Adams G P Bo G A | 2003 | Theriogenology2003,40,: | 1 |
| 7 | A microbiological study of recurrent dentinal caries显示文摘 | Fitzgerald R J Adams BO Davis ME | 1994 | Caries Res1994,28,6: | 1 |
| 8 | Exogenous control of wafollicular ve emergence in cattle显示文摘 | Bo G A Adams G P Pierson R A | 1995 | Theriogenology1995,43,: | 1 |
| 9 | A microbiological study of recurrent dentinal caries显示文摘 | Fitzgerald R J Adams BO Davis ME | 1994 | Caries Res1994,28,6: | 1 |
| 10 | Analysis of unknown compounds in gentamicin bulk samples with liquid chromatography coupled with ion trap mass spectrometry显示文摘 | LI Bo ADAMS E VAN SCHEPDAEL A | 2005 | Rapid Commun Mass Speetrom2005,020,3: | 1 |
| 11 | A microbiological study of recurrent dentinal caries显示文摘 | Fitzgerald R J Adams BO Davis ME | 1994 | Caries Res1994,286,: | 1 |
| 12 | Visualizing Lithium‐Ion Migration Pathways in Battery Materials显示文摘 | Mette ?. Fils? Michael J. Turner Gerald V. Gibbs Stefan Adams Mark A. Spackman Bo B. Iversen | 2013 | Chem Eur J2013,,46: | 1 |
| 13 | Moynahan BARD1 Participates with BRCA1 in Homology - Directed Repair of chromosome Breaks显示文摘 | Ulrica KW Marsha R Adam BO | 2003 | Molecular And Cellular Biology2003,261,9: | 1 |
| 14 | Exogenous control of follicular wave emergence in cattle显示文摘 | Bo G A Adams G P Pierson R A | 1995 | Theriogenology1995,43,: | 1 |
| 15 | Prevention of atrial fibrillation with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors显示文摘 | Oliver Adam Hans-Rupreeht Neuberger Michael Bo hm | 2008 | Circulation2008,118,: | 1 |
| 16 | Structural andbiochemical characterization of gentisate 1,2-dioxygenasefrom Escherichia coli 0157:H7显示文摘 | Adams MA Singh VK Keller BO | 2006 | MolecularMicrobiology2006,61,6: | 1 |
| 17 | Exogenous control of follicular wave emergence in cattle显示文摘 | Bo G A Adams G P Pierson R A | 1995 | Theriogenology1995,43,: | 1 |
| 18 | Ovarian superstimulatory response relative to follicular wave emergence in heifers显示文摘 | Nasser LF Adams GP Bo GA | 1993 | Therio1993,40,71: | 1 |
| 19 | A microbiological study of recurrent dentinal caries显示文摘 | Fitzgerald RJ Adams BO Davis ME | 1994 | Caries Res1994,28,3: | 1 |
| 20 | Phylogeny of Calostoma,the gelatinous-stalked puffball,based on nuclear and mitochondrial ribosomal DNA sequences显示文摘 | HUGHEY BO ADAMS GC BRUNS TD | 2000 | Mycologia2000,92,: | 1 |