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	题名	作者	年代	出处	被引量
1	Development and evaluation of a safe and effective sugar-free herbal lollipop that kills cavity-causing bacteria显示文摘Dental caries (tooth decay) is caused by a specific group of cariogenic bacteria, like Streptococcus mutans, which convert dietary sugars into acids that dissolve the mineral in tooth structure. Killing cariogenic bacteria is an effective way to control or prevent tooth decay. In a previous study, we discovered a novel compound (Glycyrrhizol A), from the extraction of licorice roots, with strong antimicrobial activity against cariogenic bacteria. In the current study, we developed a method to produce these specific herbal extracts in large quantities, and then used these extracts to develop a sugar-free lollipop that effectively kills cariogenic bacteria like Streptococcus mutans. Further studies showed that these sugar-free lollipops are safe and their antimicrobial activity is stable. Two pilot human studies indicate that a brief application of these lollipops (twice a day for ten days) led to a marked reduction of cariogenic bacteria in oral cavity among most human subjects tested. This herbal lollipop could be a novel tool to promote oral health through functional foods.	Chu-hong Hu Jian He Randal Eckert Xiao-yang Wu Li-na Li Yan Tian Renate Lux Justin A. Shuffer Faina Gelman Janet Mentes Sue Spackman Janet Bauer Maxwell H. Anderson Wen-yuan Shi	2011	International Journal of Oral Science2011，3，1：	3
2	Removal ofreal-time reverse transcription polymerase chain reaction(RT-PCR)inhibitors associated with cloacal swab samples and tissuesfor improved diagnosis of avian influenza virus by RT-PCR显示文摘	Das A Spackman E Pantin-Jackwood MJ	2009	JVet Diagn Invest2009，21，：	1
3	Maximum likelihood training of connectionist models:comparison with least squares back-propagation and logistic regression显示文摘	Spackman KA	1991	Proc ANNu Symp Comput Appl Med Care1991，，：	1
4	Role of poultry in spread of novel H7N9 influenza virus in China显示文摘	Pantin-Jackwood M J Miller P J Spackman E	2014	JVirol2014，88，10：	1
5	Effect of epidural blockade on indicators of splanchnic perfusion and gut function in critically ill patients with peritonitis: a randomised comparison of epidural bupivacaine with systemic morphine显示文摘	David R. Spackman Andrew D.M. McLeod Steven N. Prineas Richard M. Leach F. Reynolds	2000	Intensive Care Medicine2000，，11：	1
6	SNOMED clinical terms basics 显示文摘	Spackman K	2008	IHTSDO presentation2008，，：	1
7	Public-private partnerships: Lessons from the British approach显示文摘	Spackman M	2002	Economic Systems2002，26，3：	1
8	Phylogenetic analyses of type A influenza genes in natural reservoir species in North America reveals genetic variation显示文摘	Spackman E Stallknecht DE Slemons RD	2005	Virus research2005，114，12：	1
9	The pathogenesis of turkey origin reoviruses in turkeys and chickens 显示文摘	Spackman E Pantin-Jackwood M Day J M	2005	Avian Pathol2005，34，4：	1
10	Dental needs of the elder- ly in the 21st century显示文摘	Chiappelli F Bauer J Spackman S	2002	Gen Dent2002，50，4：	1
11	Analisis of amino acid by chromatography显示文摘	MooreS Spackman D H Stein W H	1958	Analytical Chemistry1958，30，：	1
12	Hirshfeld surface analysis显示文摘	Spackman M A Jayatilaka D	2009	Cryst Eng Comm2009，11，：	1
13	SNOMED Clinical Terms 显示文摘	Price C Spackman K	2000	British Journal of Healthcare Computing & Information Management2000，17，3：	1
14	Development of a real-time reverse transcriptase PCR assay for type A influenza virus and the avian H5 and H7 hemagglutinin subtypes显示文摘	Spackman E Senne D A Myers T J	2002	J Clin Microbiol2002，40，9：	1
15	Mutations in the N-terminus of the X-linked retinitis pigmentosa protein RP2 interfere with the normal targeting of the protein to the plasma membrane显示文摘	Chapple JP Hardcastle AJ Grayson C Spackman LA Willison KR Cheetham ME		0，，：	1
16	Automatic recording apparatus for use in chromatography of amino acids显示文摘	SPACKMAN D H STEIN W H STANFORD MOORE	1958	Anal Chem1958，30，7：	1
17	Automatic recording apparatus for use in chromatography of amino acids显示文摘	Spackman D H Stein W H Moore S	1958	Analytical chemistry1958，30，7：	1
18	Age at infection affects the pathogenicity of Asian highly pathogenic avian influenza H5N1 viruses in ducks显示文摘	PANTIN JACKWOOD M J SUAREZ D L SPACKMAN E	2007	Virus Res2007，130，12：	1
19	Development of real-time RT-PCR for the detection of avian influenza virus 显示文摘	SPACKMAN E SENNE D A BULAGA L L	2003	Avian Dis2003，47，：	1
20	Development of a real time reverse transeriptase PCR assay for type A influenza virus and the avian H5 and H7 hemagglutinin subtypes显示文摘	SPACKMAN E SENNE D A MYERS T J	2002	J Clin Microbiol2002，40，：	1

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