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| 1 | Managements of recurrent hepatocellular carcinoma after liver transplantation: A systematic review显示文摘AIM: To investigate the efficacy(survival) and safety of treatments for recurrent hepatocellular carcinoma(HCC) in liver transplantation(LT) patients.METHODS: Literature search was performed on available online databases without a time limit until January 2015. Clinical studies describing survival after HCC recurrence in LT patients were retrieved for a fulltext evaluation. A total of 61 studies were selected: 13 case reports, 41 retrospective case series, and 7 retrospective comparative studies.RESULTS: Based on all included studies, the mean HCC recurrence rate was 16% of all LTs for HCC. A total of 1021 LT patients experienced HCC recurrence. The median time from LT to HCC recurrence was 13 mo(range 2-132 mo). The majority of patients(67%) presented with HCC extra-hepatic recurrences, involving lung, bone, adrenal gland, peritoneal lymph nodes, and rarely the brain. Overall survival after HCC recurrence was 12.97 mo. Surgical resection of localized HCC recurrence and Sorafenib for controlling systemic spread of HCC recurrence were associated with the higher survival rates(42 and 18 mo, res-pectively). However, Sorafenib, especially when combined with m TOR, was frequently associated with severe side effects that required dose reduction or discontinuation CONCLUSION: Management of recurrent HCC in LT patients is challenging and associated with poor prognosis independently of the type of treatment. | Nicola de'Angelis Filippo Landi Maria Clotilde Carra Daniel Azoulay | 2015 | World Journal of Gastroenterology2015，21，39： | 42 |
| 2 | International consensus statement on robotic hepatectomy surgery in 2018显示文摘The robotic surgical system has been applied in liver surgery. However,controversies concerns exist regarding a variety of factors including the safety,feasibility, efficacy, and cost-effectiveness of robotic surgery. To promote the development of robotic hepatectomy, this study aimed to evaluate the current status of robotic hepatectomy and provide sixty experts' consensus and recommendations to promote its development. Based on the World Health Organization Handbook for Guideline Development, a Consensus Steering Group and a Consensus Development Group were established to determine the topics, prepare evidence-based documents, and generate recommendations. The GRADE Grid method and Delphi vote were used to formulate the recommendations. A total of 22 topics were prepared analyzed and widely discussed during the 4 meetings. Based on the published articles and expert panel opinion, 7 recommendations were generated by the GRADE method using an evidence-based method, which focused on the safety, feasibility, indication,techniques and cost-effectiveness of hepatectomy. Given that the current evidences were low to very low as evaluated by the GRADE method, further randomized-controlled trials are needed in the future to validate these recommendations. | Rong Liu Go Wakabayashi Hong-Jin Kim Gi-Hong Choi Anusak Yiengpruksawan Yuman Fong Jin He Ugo Boggi Roberto I Troisi Mikhail Efanov Daniel Azoulay Fabrizio Panaro Patrick Pessaux Xiao-Ying Wang Ji-Ye Zhu Shao-Geng Zhang Chuan-Dong Sun Zheng Wu Kai-Shan Tao Ke-Hu Yang Jia Fan Xiao-Ping Chen | 2019 | World Journal of Gastroenterology2019，25，12： | 23 |
| 3 | 2型糖尿病患者服用吡格列酮的膀胱癌风险显示文摘背景
吡格列酮是一种有争议的噻唑烷二酮类口服降糖药物,可以有效降低糖化血红蛋白(HbA1c)浓度,且降低心血管事件的发生风险,但同时也与体重增加和充血性心力衰竭风险的增加有关。尽管目前数据有限,但还是有证据显示它可能还与膀胱癌患病风险的增加有关。 | Laurent Azoulay assistant professor Hui Yin statistician Kristian B Filion assistant professor Jonathan Assayag graduate student 王子贤(编译) | 2012 | 中国处方药2012，10，5： | 17 |
| 4 | Liver Transplantation for Neuroendocrine Tumors in Europe—Results and Trends in Patient Selection: A 213-Case European Liver Transplant Registry Study显示文摘 | Yves Patrice Le Treut Emilie Grégoire Jürgen Klempnauer Jacques Belghiti Elisabeth Jouve Jan Lerut Denis Castaing Olivier Soubrane Olivier Boillot Georges Mantion Kia Homayounfar Manuel Bustamante Daniel Azoulay Philippe Wolf Marek Krawczyk Andreas Pasche | 2013 | Annals of Surgery2013，，5： | 3 |
| 5 | A Hepatocellular Carcinoma 5-Gene Score Associated With Survival of Patients After Liver Resection显示文摘 | Jean–Charles Nault Aurélien De Reyniès Augusto Villanueva Julien Calderaro Sandra Rebouissou Gabrielle Couchy Thomas Decaens Dominique Franco Sandrine Imbeaud Francis Rousseau Daniel Azoulay Jean Saric Jean–Frédéric Blanc Charles Balabaud Paulette Bioulac | 2013 | Gastroenterology2013，，1： | 3 |
| 6 | Repeat hepatectomy for recurrent colorectal metastases显示文摘 | D. A. Wicherts R. J. de Haas C. Salloum P. Andreani G. Pascal D. Sotirov R. Adam D. Castaing D. Azoulay | 2013 | Br J Surg2013，，6： | 2 |
| 7 | Tumor Progression While on Chemotherapy: A Contraindication to Liver Resection for Multiple Colorectal Metastases?显示文摘 | René Adam Gerard Pascal Denis Castaing Daniel Azoulay Valerie Delvart Bernard Paule Francis Levi Henri Bismuth | 2004 | Annals of Surgery2004，，6： | 2 |
| 8 | Hepatic resection for hepatocellular carcinoma in patients with C hild– P ugh’s A cirrhosis: is clinical evidence of portal hypertension a contraindication?显示文摘 | Roberto Santambrogio Michael D. Kluger Mara Costa Andrea Belli Matteo Barabino Alexis Laurent Enrico Opocher Daniel Azoulay Daniel Cherqui | 2012 | HPB2012，，1： | 2 |
| 9 | Therapeutic Strategies in Symptomatic Portal Biliopathy显示文摘 | Eric Vibert Daniel Azoulay Thomas Aloia Gérard Pascal Luc-Antoine Veilhan René Adam Didier Samuel Denis Castaing | 2007 | Annals of Surgery2007，，1： | 2 |
| 10 | Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy: A Model to Predict Long-term Survival显示文摘 | René Adam Valérie Delvart Gérard Pascal Adrian Valeanu Denis Castaing Daniel Azoulay Sylvie Giacchetti Bernard Paule Francis Kunstlinger Odile Ghémard Francis Levi Henri Bismuth | 2004 | Annals of Surgery2004，，4： | 2 |
| 11 | Tumor Marker Evolution: Comparison with Imaging for Assessment of Response to Chemotherapy in Patients with Colorectal Liver Metastases显示文摘 | Robbert J. Haas Dennis A. Wicherts Eduardo Flores Michel Ducreux Francis Lévi Bernard Paule Daniel Azoulay Denis Castaing Antoinette Lemoine René Adam | 2010 | Annals of Surgical Oncology2010，，4： | 2 |
| 12 | Simultaneous portal and hepatic vein embolization is better than portal embolization or ALPPS for hypertrophy of future liver remnant before major hepatectomy: A systematic review and network meta-analysis显示文摘Background:Post-hepatectomy liver failure(PHLF)is the Achilles’heel of hepatic resection for colorectal liver metastases.The most commonly used procedure to generate hypertrophy of the functional liver remnant(FLR)is portal vein embolization(PVE),which does not always lead to successful hypertrophy.Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)has been proposed to overcome the limitations of PVE.Liver venous deprivation(LVD),a technique that includes simultaneous portal and hepatic vein embolization,has also been proposed as an alternative to ALPPS.The present study aimed to conduct a systematic review as the first network meta-analysis to compare the efficacy,effectiveness,and safety of the three regenerative techniques.Data sources:A systematic search for literature was conducted using the electronic databases Embase,PubMed(MEDLINE),Google Scholar and Cochrane.Results:The time to operation was significantly shorter in the ALPPS cohort than in the PVE and LVD cohorts by 27 and 22 days,respectively.Intraoperative parameters of blood loss and the Pringle maneuver demonstrated non-significant differences between the PVE and LVD cohorts.There was evidence of a significantly higher FLR hypertrophy rate in the ALPPS cohort when compared to the PVE cohort,but non-significant differences were observed when compared to the LVD cohort.Notably,the LVD cohort demonstrated a significantly better FLR/body weight(BW)ratio compared to both the ALPPS and PVE cohorts.Both the PVE and LVD cohorts demonstrated significantly lower major morbidity rates compared to the ALPPS cohort.The LVD cohort also demonstrated a significantly lower 90-day mortality rate compared to both the PVE and ALPPS cohorts.Conclusions:LVD in adequately selected patients may induce adequate and profound FLR hypertrophy before major hepatectomy.Present evidence demonstrated significantly lower major morbidity and mortality rates in the LVD cohort than in the ALPPS and PVE cohorts. | Paschalis Gavriilidis Gabriele Marangoni Jawad Ahmad Daniel Azoulay | 2023 | Hepatobiliary & Pancreatic Diseases International2023，22，3： | 2 |
| 13 | Monitoring of the formationand dissociation of polyethylenimine/DNA complexes by two photon fluorescence corrlation spectroscopy 显示文摘 | CLAMME J P AZOULAY J MELY Y | 2003 | Biophys J2003，84，3： | 1 |
| 14 | Liver resection as a bridge to transplantation for hepatocellular carcinoma on cirrhosis: a reasonable strategy? 显示文摘 | Adam R Azoulay D Castaing D | 2003 | Ann Surg2003，238，4： | 1 |
| 15 | Liver resection as a bridge to transplantation for hepatocellular catcinoma on cirrhosis:a reasonable strategy?显示文摘 | Adam R Azoulay D Castaing D | 2003 | Ann Surg2003，238，4： | 1 |
| 16 | Determinants of postintensive care unit mortality:a prospective multicenterst study显示文摘 | Azoulay E Adrie C De Lassence A | | 0，，02： | 1 |
| 17 | Sepsis severe or septic shock: outcome according to the immune status and immunodeficiency profile 显示文摘 | Tolsma V Schwebel C Azoulay E | 2014 | Chest2014，146，5： | 1 |
| 18 | Liver resection as a bridge to transplantation for hepatocellular carcinoma on cirrhosis: a reasonable strategy? 显示文摘 | Adam R Azoulay D Castaing D | 2003 | Ann Surg2003，3238，4： | 1 |
| 19 | Risk of post-traumatic stress symptoms in family members of intensive care unit显示文摘 | Azoulay E Pochard F Chevret S | 2005 | Am J Respir Crit Care Med2005，171，9： | 1 |
| 20 | Symptoms of anxiety and depression in family members of intensive care unit patients:Ethieal hypothesis regarding decision - making capacity显示文摘 | Pochard F Azoulay E Chevret S | 2001 | Crit Care Med2001，29，： | 1 |
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