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| 1 | Ghrelin and gastrin in advanced gastric cancer before and after gastrectomy显示文摘AIM: To investigate plasma ghrelin, gastrin and growth hormone secretagogue receptor (GHS-R) expression in advanced gastric cancer (GC) before and after resection. METHODS: Seventy subjects in whom endoscopy of the upper gastrointestinal tract was performed in the Department of General Surgery at Cracow University during the past decade: (1) 25 patients with GC associated with Helicobacter pylori (H. pylori) infection; (2) 10 patients with GC 4-5 years after (total or subtotal) gastrectomy; (3) 25 healthy H. pylori-negative controls, matched by age and BMI to the above two groups; and (4) 10 GC patients 4-5 years after total gastrectomy. Ghrelin and gastrin plasma concentrations were measured by specific radioimmunoassay under fasting conditions and postprandially at 60 and 90 min after ingestion of a mixed meal. GHS-R expression was examined in biopsy samples from intact healthy mucosa and GC tissue using semi-quantitative reverse transcription-polymerase chain reaction. RESULTS: In healthy controls, fasting plasma ghrelin levels were significantly elevated and declined markedly at 60 and 90 min after a mixed meal. The concomitant enhanced ghrelin, GHS-R and gastrin expression in GC tissue over that recorded in intact mucosa, and the marked rise in plasma gastrin in these subjects under fasting conditions indicate the role of these hormonal factors in GC formation. Fasting plasma levels and postprandial response of ghrelin and gastrin appear to be inversely correlated in healthy subjects. Feeding in the controls resulted in a significant fall in plasma ghrelin with a subsequent rise in plasma gastrin, but in H. pylori-positive GC patients submitted to total or distal gastrectomy, feeding failed to affect significantly the fall in plasma ghrelin that was recorded in these patients before surgery. Fasting ghrelin concentrations were significantly lower in patients 4-5 years after total gastrectomy compared to those in healthy controls and to these in GC patients before surgery. CONCLUSION: Elevated plasma gastrin and suppression of fasting ghrelin in patients with GC suggest the existence of a close relationship between these two hormones in gastric carcinogenesis. | Anna Zub-Pokrowiecka Kazimierz Rembiasz Peter C Konturek Andrzej Budzyński Stanisaw J Konturek Marek Winiarski Wadysaw Bielański | 2011 | World Journal of Gastroenterology2011，17，4： | 7 |
| 2 | Autonomy support,basic need satisfaction and the optimal functioning of adult male and female sport participants:a test of basic needs the-ory显示文摘 | Adie J W Duda J L Ntoumanis N | | 0，，： | 1 |
| 3 | Autonomy support, basic need satisfaction and the functioning of adult male and female sport par- ticipants: A test of basic needs theory显示文摘 | Adie J W Duda J L Ntoumanis N | 2008 | Motivation and Emo- tion2008，32，3： | 1 |
| 4 | Altmetric : Enriching Scholarly Content with Arti- cle- level Discussion and Metrics显示文摘 | Adie E Roe W | 2012 | Learned Publishing2012，26，1： | 1 |
| 5 | Perceived coach-autonomy support, basic need satisfaction and the well-and ill-being of elite youth soccer players: a lon- gitudinal investigation显示文摘 | Adie J W Duda J L Ntoumanis N | 2012 | Psychology of Sport and Exer- cise2012，13，： | 1 |
| 6 | Perceptual audio data conceal ment and watemarking scheme using direct frequency domain substitution显示文摘 | Tio C M M McLoughlin I V Adi R W | 2002 | Vision Image and Signal Processing IEE Proceedings2002，149，6： | 1 |
| 7 | Autonomy support, basic need satisfaction and the optimal functioning of adult male and female sport participants: A test of basic needs theory显示文摘 | Adie J W Duda H L Ntoumanis N | 2008 | Motiv Emot2008，32，： | 1 |
| 8 | Autonomy support, basic need satisfaction, and the optimal functioning of aduk male and female sport participants: a test of basic needs the- ory显示文摘 | Adie J W Duda J L Ntoumanis N | 2008 | Motivation and Emotion2008，32，： | 1 |
| 9 | Perceived coach-autonomy support,basic need satisfaction and the well-and ill-being of elite youth soccer players:a longitudinal investigation显示文摘 | Adie J W Duda J J Ntoumanis N | 2012 | Psychology of Sport and Exercise2012，13，： | 1 |
| 10 | Susceptibility of iron castings to heat absorption from an electric arc and to hardened-layer shaping显示文摘 | Antoni W?adys?aw Or?owicz Andrzej Trytek | 2003 | Metallurgical and Materials Transactions A2003，，12： | 1 |
| 11 | Trends and dynamics of changes in calcification score over the 1-year observation period in patients on peritoneal dialysis显示文摘 | Tomasz P. Stompór Mieczys?aw Pasowicz W?adys?aw Su?owicz Aldona Dembińska-Kie? Katarzyna Janda Katarzyna Wójcik Wies?awa Tracz Anna Zdzienicka Ma?gorzata Konieczyńska Piotr Klimeczek Eve Janusz-Grzybowska | 2004 | American Journal of Kidney Diseases2004，，3： | 1 |
| 12 | An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysis显示文摘 | Tomasz Stompór Mieczys?aw Pasowicz W?adys?aw Su?owicz Aldona Dembińska-Kie? Katarzyna Janda Katarzyna Wójcik Wies?awa Tracz Anna Zdzienicka Piotr Klimeczek Eve Janusz-Grzybowska | 2003 | American Journal of Kidney Diseases2003，，1： | 1 |
| 13 | Meta-perceptions of the coach-athlete, achievement goals, and intrinsic motivation, sport participants 显示文摘 | ADIE J W JOWETT S | 2010 | J Appl Social Psychol2010，40，11： | 1 |
| 14 | Detection of Specific Helicobacter pylori DNA and Antigens in Stool Samples in Dyspeptic Patients and Healthy Subjects显示文摘 | Monika Wi?niewska Hans Olof Nilsson Leokadia B?lk‐Romaniszyn Tomasz Rechciński W?adys?aw Bielański Izabela P?aneta‐Ma?ecka Ma?gorzata P?onka Stanis?aw Konturek Torkel Wadstr?m Wies?awa Rudnicka Magdalena Chmiela | 2002 | Microbiology and Immunology2002，，10： | 1 |
| 15 | Diagnosis of Lung Cancer in Small Biopsies and Cytology: Implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification显示文摘 | Travis William D Brambilla Elisabeth Noguchi Masayuki Nicholson Andrew G Geisinger Kim Yatabe Yasushi Ishikawa Yuichi Wistuba Ignacio Flieder Douglas B Franklin Wilbur Gazdar Adi Hasleton Philip S Henderson Douglas W Kerr Keith M Petersen I | 2013 | Archives of Pathology & Laboratory Medicine2013，，5： | 1 |
| 16 | Altmetfic: enriching scholarly content with article-level discussion and metrics 显示文摘 | ADIE E ROE W | 2013 | Learned Publishing2013，26，1： | 1 |
| 17 | Notes on phenology and abundance of Psocoptera from primary and secondary dryland forest in Central Amazonia,Brazil显示文摘 | New T Adis J Morais J W | 1991 | Studies Neotropical Fauna & Environment1991，26，4： | 1 |
| 18 | Relationship between aortic pulse wave velocity, selected proinflammatory cytokines, and vascular calcification parameters in peritoneal dialysis patients显示文摘 | Marcin Krzanowski Katarzyna Janda Paulina Dumnicka Marzena Dubiel Ma?gorzata Stompór Beata Ku?nierz-Cabala Tomasz Grodzicki W?adys?aw Su?owicz | 2014 | Journal of Hypertension2014，，1： | 1 |
| 19 | Haptic texture rendering based on visual texture information: A study to achieve realistic haptic texture rendering显示文摘 | ADI W SULAIMAN S | 2009 | Visual Informaties: Bridging Research and Practice2009，5857，： | 1 |
| 20 | Autonomy support, basic need satisfaction and the optimal functioning of adult male and female sport participants: A test of basic needs theory 显示文摘 | Adie J W Duda J L Ntoumanis N | 2008 | Motivation and Emotion2008，32，： | 1 |
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