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| 1 | Arabidopsis STO/BBX24 negatively regulates UV-B signaling by interacting with COP1 and repressing HY5 transcriptional activity显示文摘UV-B (280-315nm ) 是太阳的放射的不可分的部分并且能压力 inducer 充当或作为一个发展信号。在最近的年里,增加注意被付了到 low-fluence UV-B-induced photomorphogenic 反应,在这回答的几个关键播放器被识别了,它包括 UVR8 (一个 UV-B-specific 光敏电阻器), COP1 ( WD40-repeat-containing 戒指手指蛋白质), HY5 (一个基本拉链抄写因素),并且 RUP1/2 (二 交往UVR8 蛋白质)。这里,我们报导 Arabidopsis 腌忍耐(STO/BBX24 ) ,为在植物的轻发信号的一个已知的管理者,在 UV-B-mediated photomorphogenesis 定义一个新发信号部件。bbx24 异种对 UV-B 放射过分敏感并且变得极其在 UV-B 处理下面相形见绌。由对比,转基因的线比 bbx24 和野类型的植物更微弱地回答到 UV-B 的 BBX24 overexpression。BBX24 表示是 UV-B-inducible,它在 UV-B 下面的累积要求 COP1。Co-immunoprecipitation 实验显示 BBX24 在 UV-B 照明之上在 planta 与 COP1 交往。而且, BBX24 与 HY5 交往并且在胚轴延伸的 UV-B-induced 抑制与 HY5 反对地行动。而且, BBX24 稀释 UV-B-induced HY5 累积并且压制它的抄写激活活动。一起拿,我们的结果揭示一以前在 UV-B 回答的调整光的 BBX24 的 uncharacterized 功能并且证明 BBX24 由与 COP1 和 HY5 交往作为 photomorphogenic UV-B 回答的一个否定管理者工作。UV-B-inducible 表示模式和它 HY5 活动的抑制建议 BBX24 能是反馈的一个新部件在植物发信号的 UV-B 的规章的模块。 | Lei Jiang Yan Wang Qian-Feng Li Lars Olof BjOm Jun-Xian He Shao-Shan Li | 2012 | Cell Research2012，22，6： | 21 |
| 2 | 华南地区严重危害入侵植物薇甘菊和五爪金龙入侵机制研究显示文摘薇甘菊(Mikania micrantha H.B.K.)和五爪金龙(Ipomoea cairica(L.)Sweet)是近年来在华南地区造成严重入侵危害的2种恶性杂草.该文综述了它们与入侵性相关的生理生态特征以及化感作用.同时,根据2种植物在入侵机理方面的研究现状,分析和展望了后续研究中值得关注的研究方向. | 王宇涛 麦菁 李韶山 Lars Olof BJORN | 2012 | 华南师范大学学报(自然科学版)2012，44，4： | 17 |
| 3 | Differential expression of interleukin-1/Toll-like receptor signaling regulators in microscopic and ulcerative colitis显示文摘AIM:To investigate Toll-like receptor(TLR)signaling regulators in microscopic and ulcerative colitis patients.METHODS:Total RNA and microRNA were isolated from fresh frozen colonic biopsies of non-inflamed controls and patients with active or in-remission collagenous colitis(CC),lymphocytic colitis(LC),or ulcerative colitis(UC).We compared expressions of interleukin-1receptor-associated kinase(IRAK)-2,IRAK-M,interleukin(IL)-37,microRNA(miR)-146a,miR-155,and miR-21 using quantitative real time reverse transcription polymerase chain reaction.RESULTS:IRAK-M expression was increased in LC patients with active disease in histopathological remission(LC-HR;P=0.02)and UC patients(P=0.01),but no differences in IRAK-2 expression were detected compared to controls.miR-146a,-155 and-21 expressions were increased in LC-HR(P=0.04,0.07,and 0.004)and UC(P=0.02,0.04 and 0.03)patients.miR-146a and miR-21 expressions were significantly enhanced in UC patients compared to UC remission(UC-R;P=0.01and 0.04).Likewise,active CC patients showed significantly increased expression of miR-155(P=0.003)and miR-21(P=0.006).IL-37 expression was decreased in both CC(P=0.03)and LC(P=0.04)patients with a similar trend in UC patients but not statistically significant,whilst it was increased in UC-R patients compared to controls(P=0.02)and active UC(P=0.001).CONCLUSION:The identification of differentially expressed miRNAs,IL-37,and IRAK-M suggests different pathophysiologic mechanisms in various disease stages in LC,CC,and UC. | Sezin Gunaltay Nils Nyhlin Ashok Kumar Kumawat Curt Tysk Johan Bohr Olof Hultgren Elisabeth Hultgren Hornquist | 2014 | World Journal of Gastroenterology2014，20，34： | 11 |
| 4 | Artificial root exudates and soil organic carbon mineralization in a degraded sandy grassland in northern China显示文摘Plant root exudates contain various organic and inorganic components that include glucose, citric and oxalic acid. These components affect rhizosphere microbial and microfaunal activities, but the mechanisms are not fully known. Studies concerned from degraded grassland ecosystems with low soil carbon(C) contents are rare, in spite of the global distribution of grasslands in need of restoration. All these have a high potential for carbon sequestration, with a reduced carbon content due to overutilization. An exudate component that rapidly decomposes will increase soil respiration and CO2 emission, while a component that reduces decomposition of native soil carbon can reduce CO2 emission and actually help sequestering carbon in soil. Therefore, to investigate root exudate effects on rhizosphere activity, citric acid, glucose and oxalic acid(0.6 g C/kg dry soil) were added to soils from three biotopes(grassland, fixed dune and mobile dune) located in Naiman, Horqin Sandy Land, Inner Mongolia, China) and subjected to a 24-day incubation experiment together with a control. The soils were also analyzed for general soil properties. The results show that total respiration without exudate addition was highest in grassland soil, intermediate in fixed dune and lowest in mobile dune soil. However, the proportion of native soil carbon mineralized was highest in mobile dune soil, reflecting the low C/N ratio found there. The exudate effects on CO2-C emissions and other variables differed somewhat between biotopes, but total respiration(including that from the added substrates) was significantly increased in all combinations compared with the control, except for oxalic acid addition to mobile dune soil, which reduced CO2-C emissions from native soil carbon. A small but statistically significant increase in pH by the exudate additions in grassland and fixed dune soil was observed, but there was a major decrease from acid additions to mobile dune soil. In contrast, electrical conductivity decreased in grassland and fixed dune soil and increased in mobile dune. Thus, discrete components of root exudates affected soil environmental conditions differently, and responses to root exudates in soils with low carbon contents can differ from those in normal soils. The results indicate a potential for, e.g., acid root exudates to decrease decomposition rate of soil organic matter in low carbon soils, which is of interest for both soil restoration and carbon sequestration. | YongQing LUO XueYong ZHAO Olof ANDRéN YangChun ZHU WenDa HUANG | 2014 | Journal of Arid Land2014，6，4： | 11 |
| 5 | 杨树细胞色素P450类固醇单加氧酶(CYP90)基因的克隆与分析(英文)显示文摘拟南芥的CPD基因编码一种与植物油菜素内酯(brassinosteroids,BRs)生物合成有关的细胞色素P450类固醇单加氧酶(CYP90 )。为探讨油菜素内酯这类新型植物激素在多年生木本植物中生物合成及作用的分子机理,以拟南芥CPD基因的一个cDNA片段为探针,从一种杂交杨 (Populustremula×tremudelois)的cDNA文库中分离出一个长 1 442bp的cDNA片段,然后再以这个cDNA的 5′区为探针,从这种杂交杨的基因组文库中分离出一个长 1 900bp的基因组DNA(gDNA)片段。测序结果表明,这段cDNA的 5′区与这段gDNA的 3′区重合; 由这段cDNA和gDNA组成的读框编码一个由 476个氨基酸组成的分子量为 63kD的蛋白质。该蛋白与拟南芥CYP90的同源性为 78 32%,比后者仅长 4个氨基酸,在所有已知的功能结构域,其中包括与BR生物合成密切相关的类固醇结合位点,也具有较高的同源性,表明CPD基因在一年生的草本和多年生的木本植物之间具有很高的保守性。系统树分析还表明,CYP90蛋白与番茄和玉米的矮化基因产物、鱼的all trans retinoicacid4 hydroxy lase及微澡青菌(Synechocystissp. )的细胞色素P450在进化上有较密切的联系。 | 王新宇 王崇英 Olof Olsson | 2005 | Acta Genetica Sinica2005，32，4： | 6 |
| 6 | Direct generation of linearly polarized photon emission with designated orientations from site-controlled InGaN quantum dots显示文摘Semiconductor quantum dots(QDs)have been demonstrated viable for efficient light emission applications,in particular for the emission of single photons on demand.However,the preparation of QDs emitting photons with predefined and deterministic polarization vectors has proven arduous.Access to linearly polarized photons is essential for various applications.In this report,a novel concept to directly generate linearly-polarized photons is presented.This concept is based on InGaN QDs grown on top of elongated GaN hexagonal pyramids,by which the predefined elongation determines the polarization vectors of the emitted photons from the QDs.This growth scheme should allow fabrication of ultracompact arrays of photon emitters,with a controlled polarization direction for each individual emitter. | Anders Lundskog Chih-Wei Hsu K Fredrik Karlsson Supaluck Amloy Daniel Nilsson Urban Forsberg Per Olof Holtz Erik Janzen | 2014 | Light(Science & Applications)2014，3，1： | 4 |
| 7 | Influence of confining prestress on the transition from interface defeat topenetration in ceramic targets显示文摘Replica scaled impact experiments with unconfined ceramic targets have shown that the transition velocity,i.e.,the impact velocity at which interface defeat ceases and ceramic penetration occurs,decreased as the length scale increased.A possible explanation of how this scale effect is related to the formation of a cone crack in the ceramic has been presented by the authors in an earlier paper.Here,the influence of confinement and prestress on cone cracking and transition velocity is investigated.The hypothesis is that prestress will suppress the formation and growth of the cone crack by lowering the driving stress.A set of impact experiments has been performed in which the transition velocity for four different levels of prestress has been determined.The transition velocities as a function of the level of confining prestress is compared to an analytical model for the influence of prestress on the formation and extension of the cone crack in the ceramic material.Both experiments and model indicate that prestress has a strong influence on the transition from interface defeat to penetration,although the model underestimates the influence of prestress. | Patrik LUNDBERG RenéRENSTROM Olof ANDERSSON | 2016 | Defence Technology(防务技术)2016，12，3： | 4 |
| 8 | Variability of platelet aggregation in patients with clopidogrel treatment and hip fracture: A retrospective case-control study on 112 patients显示文摘AIM: To identify the rate of non-responders to clopidogrel treatment in hip fracture patients and study how non-responders differ from controls.METHODS: In a retrospective case-control study we included 28 cases of acute proximal femoral fracture with clopidogrel treatment 2011 to 2013. Eighty-four controls from the same time period were included. Data collected included response to clopidogrel measured with multiple electrode aggregometry(MEA), intraoperative bleeding, erythrocyte transfusion, time to surgery and the incidence of adverse events up to 3 mo after surgery. RESULTS: Eight(29%) of the 28 cases were nonresponders. The median intraoperative bleeding was 300 mL(range, 0-1500), and was lower for non-responders(50 m L) but did not reach statistical significance. Erythrocyte transfusions did not differ between responders, non-responders and controls. Forty-five(40%) of 112 patients had adverse events postoperatively but the rate did not differ between patients with and without clopidogrel treatment.CONCLUSION: Almost one-third of patients withclopidogrel treatment and an acute proximal femoral fracture are non-responders to antiplatelet therapy and can be operated without delay. | Anna Clareus Inga Fredriksson Hkan Wallén Max Gordon André Stark Olof Skldenberg | 2015 | World Journal of Orthopedics2015，6，5： | 4 |
| 9 | 贫铀的军事利用与健康和环境影响显示文摘 | Jan Olof Snihs Gustav Akerblom 郝建中 胡遵素 | 2001 | 辐射防护2001，21，3： | 3 |
| 10 | 地表紫外辐射的变化显示文摘近年来紫外(UV)辐射测量的质量和数量已大大提高。不同仪器测量值之间的差异工减少到5%的量级。但长期变化的探测仍是一个问题,几乎没有历史数据可用来作本底的估计。所增加的UV辐射明显与南极春季臭氧减少相关。测量表明南极UV辐射极大值正好出现在夏至之前,南极洲Palmer站(64°S)春季臭氧耗损期间危害DNA的辐射可超过美国圣迭戈站(32°N)的夏季最高值。中纬度地区UV辐射增加较小。但对特定波长进行检查可发现,与1992/1993年北半球低柱臭氧量记录相联系的UV辐射增加是很明显的。阿根廷、智利、新西兰和澳大利亚的观测表明,这些地区的UV辐射水平比北半球相应纬度地区要高,平流层臭氧以及对流层污染的差别可能对此起了作用。对流层臭氧和气溶胶对UV-B总辐照度的减少作用是明显的。在一些地方,对流层污染自工业化前以来已有明显增加,这导致了地表UV辐射的减少。然而现在对流层污染变化对UV辐射变化的影响相对平流层臭氧减少的影响来说可能仅是一个小量。卫星测得的1979~1993年全球臭氧资料表明,在南北半球的中高纬度地区都有显著的UV-B辐射增加,而热带地区的变化小。然而这个估计的前提是在这段时期云和对流层污染保持不变。按照现在的氯氟烃(CFC)逐步禁止计划,全球UV辐射水平预计在本世纪末将达列峰值,这是与平流层氯含量出现峰值以及相应的臭氧耗损相联系的。可望在今后50年中逐步恢复到臭氧耗损之前的水平。 | Sasha Madronich Richard L.McKenzie Martyn M.Caldwell Lars Olof Bjrn 李卫 | 1995 | 人类环境杂志1995，24，3： | 3 |
| 11 | de novo转录组学分析华南地区入侵植物五爪金龙代谢特征(英文)显示文摘为探究华南地区严重入侵植物五爪金龙(Ipomoea cairica)生物入侵的分子机制,对五爪金龙及其近缘种七爪金龙(I.digitata)和裂叶牵牛(I.nil)进行de novo转录组测序和组装,得到56551条unigenes,其中56522条得到注释,7815条GO注释,15615条COG注释,180201条KEGG数据库注释。转录组分析结果表明,五爪金龙氮代谢通路关键酶基因的表达高于对照。次生代谢关键酶(PAL、4CL、CAD、查耳酮合酶、苯基丙乙烯酮异构酶、槲皮黄3-O-甲基转移酶等)基因在五爪金龙与七爪金龙及裂叶牵牛中均得到协同性的差异表达,而这些代谢通路指导的产物合成对五爪金龙的抗逆境能力、生长、化感作用等均起关键作用。关键基因的RT-q PCR验证结果与转录组结果具有一致性。因此,这从分子生物学层面上对解释五爪金龙在华南地区的入侵机制提供了新的证据。 | 耿妍 陈玲玲 鲁焕 宁婵娟 BJORN Lars Olof 李韶山 | 2016 | 热带亚热带植物学报2016，24，2： | 3 |
| 12 | Complications From Inflammatory Bowel Disease During Pregnancy and Delivery显示文摘 | Gabriella Br?ms Fredrik Granath Marie Linder Olof Stephansson Maria Elmberg Helle Kieler | 2012 | Clinical Gastroenterology and Hepatology2012，，11： | 2 |
| 13 | Glyconanomaterials: Emerging applications in biomedical research显示文摘糖类在自然组成最丰富的有机物,用作结构的部件和精力来源,并且调停大量细胞的活动。有不同光、磁性、电子的性质的 nanomaterials 的出现为生物医学的研究和应用见证这些材料的快速的采纳。有大特定的表面区域的各种各样的形状和尺寸的 Nanomaterials 能被用作多价的脚手架介绍糖类 ligands。产生 glyconanomaterials 有效地放大调停 glycan 的相互作用,使使用这些材料察觉到,成像,诊断,和治疗可能。在这评论,我们为各种各样的 glyconanomaterials 的准备总结合成策略。在这些 glyconanomaterials 在察觉到和蛋白质和房间的区别,以及在成像被使用了的地方,例子被给药物治疗 glycan 的细胞的回答。 | Xuan Chen Olof Ramstrom Mingdi Yan | 2014 | Nano Research2014，7，10： | 2 |
| 14 | 包括岛国在内的东非的海岸带管理:问题和应对行动述评显示文摘东非和西印度洋岛国的海岸线绵延11000多km,其海岸带居住着3000万~3500万人。这是一个具有显著地理、生态和人文多样性差异的地区,海岸生境独特,生物多样性程度很高。但由于普遍的贫穷,再加上人口迅速增长、不适当或不良的发展部署以及缺乏综合规划管理等因素,已导致许多海岸地区的环境退化和资源耗竭,还伴随着各种利害关系牵连者之间的冲突日益增加。严重的海岸污染和生境破坏往往限于主要城市的附近地区。然而,这些影响正在向人口较稀少的地区逐渐扩展。海岸带综合管理(ICZM)在该地区已被承认为一种有效的资源管理方法,而且许多ICZM计划已经在区域、国家和地方各层次上启动。本文评述这些计划,特别要涉及最近的和正在进行的ICZM行动,它们是由瑞典国际开发署(SIDA)以及其他赞助者和联合国有关机构资助的。 | Christine A.Coughanowr Magnus N.Ngoile Olof Lindén 朱志辉 | 1995 | 人类环境杂志1995，24，7： | 2 |
| 15 | A prospective study of obesity and cancer risk (Sweden)显示文摘 | Alicja Wolk Gloria Gridley Malin Svensson Olof Nyrén Joseph K. McLaughlin Joseph F. Fraumeni Hans-Olov Adami | 2001 | Cancer Causes and Control2001，，1： | 2 |
| 16 | Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death显示文摘 | Alexander Seiler Manuela Schneider Heidi F?rster Stephan Roth Eva K. Wirth Carsten Culmsee Nikolaus Plesnila Elisabeth Kremmer Olof R?dmark Wolfgang Wurst Georg W. Bornkamm Ulrich Schweizer Marcus Conrad | 2008 | Cell Metabolism2008，，3： | 2 |
| 17 | Predicting Subcellular Localization of Proteins Based on their N-terminal Amino Acid Sequence显示文摘 | Olof Emanuelsson Henrik Nielsen S?ren Brunak Gunnar von Heijne | 2000 | Journal of Molecular Biology2000，，4： | 2 |
| 18 | 环境变化背景下北极生物的多样性、分布及其适应性显示文摘生物个体是对气候变化和紫外线B(UV-B)辐射变化产生反应的基础,而且这种反应会在各种时间尺度上发生。北极地区的动物、植物以及微生物种类的多样性从表面上看是低的,而且从北方针叶林到极地荒漠逐渐减少,但其原始物种却很丰富。与这种物种多样性随纬向梯度减少的趋势相反,一些空间分布范围很广的单一优势物神的优势度则呈增长趋势。全球气候变暖可能会减少该地区的物种多样性,并限制到这些物种的分布范围,尤其是在该地区生物分布的北部边缘,一些极地特有的动物和植物种类会面临着灭绝的危险。最有可能侵入苔原地带的物种是那些目前生存在极地外缘的北方地区生物。许多植物都具有自身的特征使它们能够在以下环境中生存;短暂的无冰雪覆盖的生长季节,低的太阳高度角,永久冻结地带及低的土壤温度,贫乏的养分获取条件以及极少的物理扰动。以上这些特征有些可能会限制当地物种对气候变暖的反应,但其最主要的因素是这些物种与那些潜在的入侵物种相比缺乏竞争能力。北极地区陆生动物拥有许多适应特性,这使它们能够适应北极地区剧烈的温度变化。许多动物通过冬眠或迁移来逃避极地地区的恶劣天气和资源短缺。北极地区动物生存的生物环境则相对简单:几乎没有天敌、竞争者、疾病、寄生生物,但同时食物资源也很短缺。极地陆生动物可能对由气候变化带来的温暖而干旱的夏季非常不适应,这种变化将会影响到动物的迁移路线、途中栖息地,并会改变冬季积雪的状况和冻融的循环过程。气候变化还会改变动物繁殖和发育的季节,并会引来新的竞争者、捕食者、寄生生物以及疾病等。极地微生物也能很好地适应该地区的气候:一些微生物甚至在-39℃的低温下还能进行代谢活动。蓝藻细菌和藻类生物有着很广泛的适应策略,这能够使它们避免(至少可以减少)紫外线的伤害。微生物能够忍受许多环境条件,而且其生长周期很短,这些特点将使它们能很快适应新的生存环境。与此形成对比的是,极地植物和动物很可能通过改变其分布范围而不是积极的生物进化来适应环境的变暧。 | Terry V.Callaghan Lars Olof Bjrn Yuri Chernov Terry Chapin Torben R.Christensen Brian Huntley Rolf A.Ims Margareta Johansson Dyanna Jolly Sven Jonasson Nadya Matveyeva Nicolai Panikov Walter Oechel Gus Shaver Josef Elster Heikki Henttonen Kari Laine Kari Taulavuori Erja Taulavuori Christoph Zckler 何永涛 | 2004 | AMBIO-人类环境杂志2004，33，B11： | 2 |
| 19 | How does aceessibility to knowledge sources affect the innovativeness of corporations? --evidence from Sweden 显示文摘 | MARTIN ERSSON OLOF EJERMO | 2000 | Ann Reg Sci2000，5，39： | 1 |
| 20 | Field - Dependence/Independence: Ability in Relation to Mobility Fixity显示文摘 | Hansson S Birger Ryden Olof O Johnsson Per | 1986 | Perceptual and Motor Skills1986，63，1： | 1 |
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