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| 1 | 用于三维裂纹扩展分析的有限变形不可逆内聚元显示文摘为了能准确和高效的跟踪动态裂纹扩展,我们发展了三维有限变形的内聚元和一系列不可逆内聚力关系.该内聚元通过采用不可逆内聚力关系来控制裂纹两侧物质的逐渐分离和形成自由表面,这一点可类比于传统有限元对块体材料的离散化.为了展示该方法的预测能力及便于灵活使用的特点,我们模拟了Zehnder和Rosakis所做的重物落下动态断裂实验,值得注意的是该方法可以近似模拟出裂尖的轨迹. | M. Ortiz A. Pandolfi 申胜平(译) 刘彬(译) 胡更开(校) | 2008 | 力学进展2008，38，5： | 2 |
| 2 | Finite-element simulation of firearm injury to the human cranium显示文摘 | A. Mota W. S. Klug M. Ortiz A. Pandolfi | 2003 | Computational Mechanics (-)2003，，1： | 1 |
| 3 | Multiple Stenting of Refractory Pancreatic Duct Strictures in Severe Chronic Pancreatitis: Long-term Results显示文摘 | G. Costamagna M. Bulajic A. Tringali M. Pandolfi A. Gabbrielli C. Spada L. Petruzziello P. Familiari M. Mutignani | 2006 | Endoscopy2006，，03： | 1 |
| 4 | Determination by flow cytometry of the chromosome doubling capacity of colchicine and oryzalin in gynogenetic haploids of gerbera显示文摘 | A. Tosca R. Pandolfi S. Citterio A. Fasoli S. Sgorbati | 1995 | Plant Cell Reports1995，，7： | 1 |
| 5 | Characterization of Ga 2 O 3 based MRISiC hydrogen gas sensors显示文摘 | A. Trinchi S. Kaciulis L. Pandolfi M.K. Ghantasala Y.X. Li W. Wlodarski S. Viticoli E. Comini G. Sberveglieri | 2004 | Sensors & Actuators: B. Chemical2004，，： | 1 |
| 6 | Shifting ecological baselines and the demise of Acropora cervicornis in the western North Atlantic and Caribbean Province: a Pleistocene perspective显示文摘 | B. J. Greenstein H. A. Curran J. M. Pandolfi | 1998 | Coral Reefs1998，，3： | 1 |
| 7 | Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy显示文摘Although targeted therapies have proven effective and even curative in human leukaemia, resistance often ensues. IDH enzymes are mutated in ~20% of human AML, with targeted therapies under clinical evaluation. We here characterize leukaemia evolution from mutant IDH2 (mIDH2)-dependence to independence identifying key targetable vulnerabilities of mIDH2 leukaemia that are retained during evolution and progression from early to late stages. Mechanistically, we find that mIDH2 leukaemia are metastable and vulnerable at two distinct levels. On the one hand, they are characterized by oxidative and genotoxic stress, in spite of increased 1-carbon metabolism and glutathione levels. On the other hand, mIDH2 leukaemia display inhibition of LSD1 and a resulting transcriptional signature of all-trans retinoic acid (ATRA) sensitization, in spite of a state of suppressed ATRA signalling due to increased levels of PIN1. We further identify GSH/ROS and PIN1/LSD1 as critical nodes for leukaemia maintenance and the combination of ATRA and arsenic trioxide (ATO) as a key therapeutic modality to target these vulnerabilities. Strikingly, we demonstrate that the combination of ATRA and ATO proves to be a powerfully synergistic and effective therapy in a number of mouse and human mIDH1/2 leukemic models. Thus, our findings pave the way towards the treatment of a sizable fraction of human AMLs through targeted APL-like combinatorial therapies. | Vera Mugoni Riccardo Panella Giulia Cheloni Ming Chen Olga Pozdnyakova Dina Stroopinsky Jlenia Guarnerio Emanuele Monteleone Jonathan David Lee Lourdes Mendez Archita Venugopal Menon Jon Christopher Aster Andrew A. Lane Richard Maury Stone Ilene Galinsky José Cervera Zamora Francesco Lo-Coco Manoj Kumar Bhasin David Avigan Letizia Longo John Gerard Clohessy Pier Paolo Pandolfi | 2019 | Cell Research2019，29，6： | 1 |
| 8 | 查看详情显示文摘 | Soiget S. L Maslak P Wang Z. G Jhanwar S. Calleja E. Dardashti L.J. Corso D. DeBlasio A. Gabrilove J. Scheinberg D.A. Pandolfi P.P. War rell R.P.N | | 0，，： | 1 |
| 9 | Acute hyperglycemia and acute hyperinsulinemia decrease plasma fibrinolytic activity and increase plasminogen activator inhibitor type 1 in the rat显示文摘 | A. Pandolfi A. Giaccari C. Cilli M. M. Alberta L. Morviducci E. A. De Filippis A. Buongiorno G. Pellegrini G. Capani A. Consoli | 2001 | Acta Diabetologica2001，，2： | 1 |
| 10 | Particulate Matter and Daily Mortality: A Case-Crossover Analysis of Individual Effect Modifiers显示文摘 | Francesco Forastiere Massimo Stafoggia Giovanna Berti Luigi Bisanti Achille Cernigliaro Monica Chiusolo Sandra Mallone Rossella Miglio Paolo Pandolfi Magda Rognoni Maria Serinelli Roberta Tessari Mariangela Vigotti Carlo A. Perucci | 2008 | Epidemiology2008，，4： | 1 |
| 11 | Hydroxyapatite coating of titanium by biomimetic method显示文摘 | A. Costantini G. Luciani F. Branda L. Ambrosio G. Mattogno L. Pandolfi | 2002 | Journal of Materials Science: Materials in Medicine2002，，9： | 1 |
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