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| 1 | Correlates of symptoms of depression and anxiety in chronic hemodialysis patients显示文摘 | Maurizio Bossola Claudia Ciciarelli Gian Luigi Conte Carlo Vulpio Giovanna Luciani Luigi Tazza | 2010 | General Hospital Psychiatry2010,,2: | 3 |
| 2 | Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring显示文摘现在有充分证据,对在使肥沃的后代显型的父亲的贡献多于公平 DNA。然而,这 nongenetic 继承的身份和机制糟糕被理解。在这个研究区域的更重要的问题之一是:在精子 DNA methylation 的变化为后代有 phenotypic 后果吗?我们以前报导了肥胖的雄的老鼠的后代与控制相比改变了葡萄糖新陈代谢并且这效果通过 nongenetic 工具被继承。这里,我们用一样的协议在一个新队描述调查进精子 DNA methylation。在高脂肪的节食的雄的老鼠是 30% 比喂控制的男性重在交配的时候(16-19 星期旧, n = 14/14 ) 。一小(0.25%) 在全部的 5-methyl-2 ’ 增加; -deoxycytidine 被液体层析双人脚踏车团 spectrometry 在肥胖的老鼠精子检测。那 retrotransposon DNA methylation 在精子说的有定序的充实蛋白质的染色体(MBD-Seq ) 和 pyrosequencing 揭示了的 methyl-CpG 绑定领域的染色体的重复部分的检查没被肥胖,而是 methylation 在整个染色体在卫星重复影响被增加。然而,从男 27-week-old 后代从的肌肉,肝,和精子的检查肥胖并且控制父亲(从 8 生的 n = 的两个组) 表明正常 DNA methylation 层次在后代开发期间被恢复。而且,没有变化在肥胖的老鼠精子在三个 genomic 印记被发现。我们的调查结果为 transgenerational epigenetic reprogramming 有含意。他们建议 postfertilization 机制为使导致 environmentally 的 DNA methylation 在精子房间改变的一些正常化存在。 | Neil A Youngson Virginie Lecomte Christopher A Maloney Preston Leung Jia Liu Luke B Hesson Fabio Luciani Lutz Krause Margaret J Morris | 2016 | Asian Journal of Andrology2016,18,6: | 3 |
| 3 | Current and future circulating biomarkers for cardiac amyloidosis显示文摘心脏的淀粉样变性病(CA ) 包括影响心肌层的医药条件的一个异构的组。它与严厉,流行和进化的可变的度与 proteinaceous 介绍渗入。尽管有这异质,错误的蛋白质合拢是普通 pathophysiologic 过程,产出日益增多地发展并且最终形成淀粉的纤维的单个错误褶层蛋白质(单体) 的形成。由从起源的机关外面播种,另外,称为 oligomers 的中介转移并且重启这个过程。如此的自我回应的行为象主要的一样使第二等的影响机关重要。不幸地, CA 能在它的自然历史的一个迟了的阶段临床上挑战性、仅仅暗示,让一扇狭窄的治疗学的时间窗户可得到。考虑到淀粉样变性病的进化性质,这里,我们越过 CA 子类型与不同特性和适用性基于时间舞台建议当前使用的 biomarkers 的一个新分类。早标记(免费的轻链,浆液淀粉的 A, 2-microglobulin, osteopontin 和 osteoprotegerin ) 能为疾病察觉被采用。中间的标记[tumorigenicity 的可溶的抑制 2 (sST-2 ) , midregional proadrenomedullin (MR-proADM ) , von Willebrand 因素(vWF ) , hepatocyte 生长因素(HGF ) ,矩阵 metalloproteinases (MMP ) 和织物禁止者 metalloproteinases (TIMP )] 能在心肌的损坏的生物机制上提供信息。作为在心失败,迟了阶段的 biomarkers (troponins 和 natriuretic 肽) 能在 CA 帮助临床医生做好预后和治疗学的反应评估。如此的调查结果在 CA 上为我们的当前的知识产生了一个显著基础。不过,我们想象目标为能够检测合拢缺点的在上游的事件的 biomarkers 的一个未来班,它将最终扩展治疗学的窗户。 | Marco LUCIANI Luca TRONCONE Federica DEL MONTE | 2018 | Acta Pharmacologica Sinica2018,39,7: | 3 |
| 4 | Liver Resection for Transplantable Hepatocellular Carcinoma: Long-Term Survival and Role of Secondary Liver Transplantation显示文摘 | Daniel Cherqui Alexis Laurent Nicolas Mocellin Claude Tayar Alain Luciani Jeanne Tran Van Nhieu Thomas Decaens Monika Hurtova Riccardo Memeo Ariane Mallat Christophe Duvoux | 2009 | Annals of Surgery2009,,5: | 2 |
| 5 | Atmospheric aerosol in an urban aero-measurement of TSP and PM10 standards and pulmonary deposition assessments 显示文摘 | Berico M Luciani A Formignani M | 1997 | Atmospheric Environment1997,31,21: | 1 |
| 6 | Intermittent high glucose concentrations reduce neuronal precursor survival by altering the IGF system:the involvement of the neuroprotective factor DHCR24(Seladin-1)显示文摘 | Giannini S Benvenuti S Luciani P | 2008 | J Endocrinol2008,198,3: | 1 |
| 7 | Incidental renal cell carcinoma-age and stage characterization and clinical implications:study of 1092 patients(1982-1997)显示文摘 | Luciani LG Cestari R Tallarigo C | 2000 | Urology2000,56,1: | 1 |
| 8 | Unusual presentation of haemophilia in two paediatric patients显示文摘 | Maia De Luca Francesca I. Calò Carducci Valeria Pansini Valentina Coletti Filippo M. Tucci Marco Cirillo Maura Acquila Maria Patrizia Bicocchi Patrizia D’Argenio Matteo Luciani | 2013 | Blood Coagulation & Fibrinolysis2013,,6: | 1 |
| 9 | The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A显示文摘 | LUCIANI M G HUTCHINS J R ZhELEVA D | 2000 | J Mol Biol2000,300,3: | 1 |
| 10 | Telomeric 22q13 deletions resulting from rings, simple deletions, and translocations: cytogenetic, molecular, and clinical analyses of 32 new observations显示文摘 | Luciani J J de Mas P Depetris D Mignon-Ravix C Bottani A Prieur M | 2003 | J Med Genet2003,40,9: | 1 |
| 11 | Phase separation and gelation of epoxy resin/hyperbranched polymer blends 显示文摘 | MEZZENGA R LUCIANI A MANSON J-A E P | 2002 | Polymer Engineering and Science2002,42,: | 1 |
| 12 | The Selli Level of the Gargano Promontory, Apulia, southern Italy: foraminiferal and calcareous nannofossil data显示文摘 | Cobianchi M Luciani V Menegatti A | 1999 | Cretaceous Re search1999,20,3: | 1 |
| 13 | Lymph node imaging: Basic principles显示文摘 | Luciani A Itti E Rahmouni A | 2006 | Eur J Radiol2006,58,3: | 1 |
| 14 | Incidental renal cell carcinomaage and stage characterization and clinical implications: study of 1092 patients (1982-1997) 显示文摘 | Luciani LG Gestari R Tallarigo C | 2010 | Urology2010,56,1: | 1 |
| 15 | Les pseudolsions hpatiques 显示文摘 | Mathieu D Luciani A Achab A | 2001 | Gastroenterol Clin Biol2001,25,4: | 1 |
| 16 | Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women 显示文摘 | GOODSON W H LUCIANI M G SAYEED S A | 2011 | Carcinogenesis2011,32,11: | 1 |
| 17 | Clinical analysis of multiple primary malignancies in the elderly显示文摘 | Luciani A Ascione G Marussi D | 2009 | Med Oneol2009,26,1: | 1 |
| 18 | Global and local path planning in natural environment by physical modeling显示文摘 | Chanclou B Luciani A | 1996 | Intelligent Robotic and System ''96 IROS 96 Proceedings of the 1996 IEEE/RSJ International Conference on1996,3,: | 1 |
| 19 | Lupus anticoagulants are stronger risk factors of thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome:a systematic review of the literature显示文摘 | Galli M Luciani D Bertolini G | 2003 | Blood2003,101,5: | 1 |
| 20 | Lymph node imaging: basic principles显示文摘 | Luciani A Itti E Rahmouni A | 2006 | Eur J Radiol2006,58,3: | 1 |