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| 1 | Iatrogenic esophago-tracheal fistula:Challenges in diagnosis and management显示文摘Esophageo-tracheal fistula is a rare condition,and in most cases such fistulas are caused by malignant disease or emergency endotracheal intubation.A case where a wrapped tablet produced a fistula between the esophagus and trachea is described.The patient is a male born in 1938 who swallowed a tablet without unwrapping it.The patient was treated with selfexpanding metal stents(SEMS),but closure of the fistula was not achieved.Different examinations and treatment options are discussed.Surgical treatment for this condition has demonstrated considerable mortality and morbidity.In some cases closure of the fistula can be achieved by use of SEMS.Although we advise treatment of such cases with SEMS,in some cases treatment with stents will prove troublesome and the risk/benefit analysis will have to be reevaluated. | istein Hovde yvind Haugen Lie Per Arthur Johansson ystein Stubhaug Egil Johnson Bjrn Hofstad Truls Hauge | 2013 | World Journal of Gastroenterology2013，19，4： | 5 |
| 2 | Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer显示文摘 | Morten Hagness Aksel Foss P?l-Dag Line Tim Scholz P?l Foyn J?rgensen Bjarte Fosby Kirsten Muri Boberg ?ystein Mathisen Ivar P. Gladhaug Tor Skatvedt Egge Steinar Solberg John Hausken Svein Dueland | 2013 | Annals of Surgery2013，，5： | 4 |
| 3 | Effects of insulin and pathway inhibitors on the PI3K-Akt- mTOR phosphorylation profile in acute myeloid leukemia cells显示文摘The phosphatidylinositol 3-kinase(PI3K)-Akt-mechanistic target of rapamycin(mTOR)pathway is constitutively activated in human acute myeloid leukemia(AML)cells and is regarded as a possible therapeutic target.Insulin is an agonist of this pathway and a growth factor for AML cells.We characterized the effect of insulin on the phosphorylation of 10 mediators in the main track of the PI3K-Akt-mTOR pathway in AML cells from 76 consecutive patients.The overall results showed that insulin significantly increased the phosphorylation of all investigated mediators.However,insulin effects on the pathway activation profile varied among patients,and increased phosphorylation in all mediators was observed only in a minority of patients;in other patients,insulin had divergent effects.Global gene expression profiling and proteomic/phosphoproteomic comparisons suggested that AML cells from these two patient subsets differed with regard to AML cell differentiation,transcriptional regulation,RNA metabolism,and cellular metabolism.Strong insulin-induced phosphorylation was associated with weakened antiproliferative effects of metabolic inhibitors.PI3K,Akt,and mTOR inhibitors also caused divergent effects on the overall pathway phosphorylation profile in the presence of insulin,although PI3K and Akt inhibition caused a general reduction in Akt pT308 and 4EBP1 pT36/pT45 phosphorylation.For Akt inhibition,the phosphorylation of upstream mediators was generally increased or unaltered.In contrast,mTOR inhibition reduced mTOR pS2448 and S6 pS244 phosphorylation but increased Akt pT308 phosphorylation.In conclusion,the effects of both insulin and PI3K-Akt-mTOR inhibitors differ between AML patient subsets,and differences in insulin responsiveness are associated with differential susceptibility to metabolic targeting. | Ina Nepstad Kimberley Joanne Hatfield Ida Sofie Grønningsæter Elise Aasebø Maria Hernandez-Valladares Karen Marie Hagen Kristin Paulsen Rye Frode SBerven Frode Selheim Håkon Reikvam Øystein Bruserud | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 4 |
| 4 | Laparoscopic resection of exocrine carcinoma in central and distal pancreas results in a high rate of radical resections and long postoperative survival显示文摘 | Irina Pavlik Marangos Trond Buanes B?rd I. R?sok Airazat M. Kazaryan Arne R. Rosseland Krzysztof Grzyb Olaug Villanger ?ystein Mathisen Ivar P. Gladhaug Bj?rn Edwin | 2012 | Surgery2012，，5： | 3 |
| 5 | Hepatic resection for colorectal metastases: Can preoperative scoring predict patient outcome?显示文摘 | Tom Mala M.D. Geir B?hler M.D. ?ystein Mathisen M.D. Ph.D. Anstein Bergan M.D. Ph.D. Odd S?reide M.D. Ph.D | 2002 | World Journal of Surgery2002，，11： | 2 |
| 6 | Long-Term Outcome of Laparoscopic Surgery for Pancreatic Neuroendocrine Tumors显示文摘 | Sven-Petter Haugvik Irina Pavlik Marangos B?rd Ingvald R?sok Ewa Pomianowska Ivar Prydz Gladhaug ?ystein Mathisen Bj?rn Edwin | 2013 | World Journal of Surgery2013，，3： | 2 |
| 7 | A dual sensor flow imaging tomographic system显示文摘 | JOHANSEN GA FR YSTEIN T HJERTAKER B T | 1996 | Meas-urement Science and Technology1996，7，： | 1 |
| 8 | Antimicrobial susceptibility of Haemophilus parasuis and Histophilus somni from pigs and cattle in Denmark显示文摘 | Frank M Aarestrup Anne Mette Seyfarth ?ystein Angen | 2004 | Veterinary Microbiology2004，，2： | 1 |
| 9 | Development of an improved species specific PCR test for detection of Haemophilus parasuis 显示文摘 | Фystein Angen Simone Oliveira Peter Ahrens | 2007 | Veterinary Mi- crobiology2007，119，24： | 1 |
| 10 | Configuring value for competitive advantage on chains,and networks显示文摘 | Stabell Charles B Fjeldstad Ystein D | 1998 | Strategic Management Journal1998，19，2： | 1 |
| 11 | The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease显示文摘 | ? ystein Brenna Torunn Bruland Marianne W. Furnes Atle van Beelen Granlund Ignat Drozdov Johanna Emg? rd Gunnar Br? nstad Mark Kidd Arne K. Sandvik Bj? rn I. Gustafsson | 2015 | Scandinavian Journal of Gastroenterology2015，，10： | 1 |
| 12 | Dehydrins expression related to timing of bud burst in Norway spruce显示文摘 | Igor A. Yakovlev Daniel K. A. Asante Carl Gunnar Fossdal Jouni Partanen Olavi Junttila ?ystein Johnsen | 2008 | Planta2008，，3： | 1 |
| 13 | Performance and governance in microfinance institutions显示文摘 | Mersland Roy R ystein Strm | 2009 | Journal of Banking and Finance2009，33，4： | 1 |
| 14 | Risk-based capital requirments and bank portfolio risk显示文摘 | Фystein Gjerde Kristian Semen | 1995 | Journal of Banking and Finance1995，，19： | 1 |
| 15 | An 8- bit,200 MSPS Folding and Interpolating ADC显示文摘 | Ystein Moldsvor | 1998 | Analog Integrated Circuits and Signal Proeessing1998，，15： | 1 |
| 16 | 转折期的区域性大气污染显示文摘在欧洲,跨国界的大气污染控制已经取得成功。许多主要污染物排放量正在下降,受到污染物损害的生态系统呈现恢复的迹象。CAFE项目是在欧洲委员会(the European Commission)和远程跨境大气污染协议(CLRTAP)框架下制定的;而在CAFE范围内制定了战略措施,其目的是大幅度加强区域性大气污染的控制,特别是小颗粒污染物的控制。在此文中,我们着重讨论新的战略措施,但是主要关心社会经济的发展趋势和气候变化的反馈作用;它们也许会对新战略措施的结果产生重大影响,对此我们迄今尚未加以考虑。我们要特别指出:在欧洲,升高的夏季温度,以及在其它地区,污染物排放量(包括国际船运业的)的上升对空气质量产生影响。欧洲污染物排放的下降量和增加的背景污染,将会慢慢形成灰色的对流层,这与过去的情形不同。在以往的情形中,主导性的排放发生在欧洲和北美(黑),而其他地方排放量较低(白)。在欧洲及北半球的其他区域,有必要采取一种整个半球合作的方式来防止大气的进一步污染。 | Peringe Grennfelt Φystein Hov 赵军 | 2005 | AMBIO-人类环境杂志2005，34，1： | 1 |
| 17 | Sensor systems for use in reinforced concrete structures显示文摘 | John McCartera W φystein Venneslandb | 2004 | Construction Building Mater2004，18，： | 1 |
| 18 | Heterogeneous nucleation on rough surfaces:implications to atmospheric aerosols显示文摘 | Lazaridis M Hov ystein Eleftheriadis K | 2000 | Atmospheric Research2000，55，： | 1 |
| 19 | Salt effects on lignosulfonate and Kraft lignin stabilized O/W-emulsions studied by means of electrical conductivity and video-enhanced microscopy 显示文摘 | Stig Are Gundersen фystein Saether Johan Sjo ' blom | 2001 | Colloids and Surfaces: A: Physicochemical and Engineering Aspects2001，，186： | 1 |
| 20 | A model strategy for the simulation of chlorinated hydrocarbon distributions in the global environment显示文摘 | Asbj?rn Strand ?ystein Hov | 1996 | Water Air and Soil Pollution (-)1996，，1： | 1 |
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