|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 黄芩甙元和黄芩甙对皮肤真菌与细菌抑制作用的研究显示文摘本文研究了黄芩甙和黄芩甙元对十七种皮肤致病真菌与十六种皮肤细菌的抑制活性。在琼脂药物培养基上,黄芩甙元表现出了对酵母型真菌高度的选择抑制作用,其最低抑制浓度MIC在70~100μg/ml之间,而对皮肤癣菌和丝状霉菌没有活性;黄芩甙则对所有的供试真菌几乎没有作用。另外,与脚气和腋臭有关的负责菌如固着微球菌、表皮葡萄球菌、人型葡萄球菌和干燥棒杆菌等,在黄苓甙元浓度为250μg/ml的条件下,其生长繁殖也能完全抑制。黄芩甙元的抗菌活性可能与其结构第七位羟基的存在有关。 | 杨得坡 胡海燕 黄世亮 Jean-Pierre Chaumont Joělle Millet | 2000 | 中药材2000，23，5： | 64 |
| 2 | 稻瘟病菌株CH63和TH16杂交组合的遗传图谱构建及无毒基因定位显示文摘测定了CH63和TH16杂交后代(F1 代子囊孢子群体)在36个水稻品种上的致病性,依据F1 代子囊孢子群体在不同品种上的无毒性/毒性表型和SSR、SCAR和RAPD等分子标记的多态性位点共分离构建了稻瘟病菌的遗传图谱。图谱共有151个标记位点,7个连锁群,全长1038.4 cM。由杂交后代在不同品种上的无毒性/毒性分离鉴定出CH63菌株持有多个无毒基因,在该遗传图谱中初步定位了Avr2 K59、Avr C105 TTP1、Avr Zh156、Avr Xuan1641、Avr Xuan6392 和Avr C103 TTP 6个无毒基因,分别定位在第1、第4和第7染色体上。 | 王艳丽 Claudia KAYE Amandine BORDAT Henri ADREIT Jo■lle MILLAZZO 郑小波 沈瑛 Didier THARREAU | 2005 | 中国水稻科学2005，19，2： | 9 |
| 3 | 用LC-MS/MS方法筛查饮用水矿泉水和环境水中PPT级的165种农药显示文摘 | Didier ORTELLI Patrick EDDER Joёlle NANOZ Claude CORVI | 2007 | 环境化学2007，26，3： | 4 |
| 4 | Lanreotide in Metastatic Enteropancreatic Neuroendocrine Tumors显示文摘 | Martyn E. Caplin Marianne Pavel Jaros?aw B. ?wik?a Alexandria T. Phan Markus Raderer Eva Sedlá?ková Guillaume Cadiot Edward M. Wolin Jaume Capdevila Lucy Wall Guido Rindi Alison Langley Séverine Martinez Jo?lle Blumberg Philippe Ruszniewski | 2014 | The New England Journal of Medicine2014，，： | 3 |
| 5 | 角蛋白酶在真菌侵染皮肤过程中的作用显示文摘具有高度交联三维结构的角蛋白对各种物理、化学和一般性的蛋白水解酶攻击具有很强的抗性,但在底物的诱导下,皮肤真菌分泌的用蛋白酶可特异性地水解该蛋白。在真菌感染皮肤过程中,用蛋白酶与菌丝的机械侵入和化学还原作用配合,使病原菌获得营养和侵入皮肤。在抗真菌药物的配方中,加入角蛋白酶,可帮助活性因子通过皮肤屏障或抑制病原菌繁殖。 | 杨得坡 Jean-Pierre Chaumont 彭劲甫 王发松 Joёlle Millet | 2000 | 微生物学杂志2000，20，2： | 3 |
| 6 | Relationship between texture and pectin composition of two apple cultivars during storage显示文摘 | Ludivine Billy Emira Mehinagic Ga?lle Royer Catherine M.G.C. Renard Ga?lle Arvisenet Carole Prost Frédérique Jourjon | 2007 | Postharvest Biology and Technology2007，，3： | 3 |
| 7 | Spectral analysis and fingerprinting for biomedia characterisation显示文摘 | Marie-No?lle Pons Sébastien Le Bonté Olivier Potier | 2004 | Journal of Biotechnology2004，，1： | 2 |
| 8 | Probiotic yeasts: Anti-inflammatory potential of various non-pathogenic strains in experimental colitis in mice显示文摘AIM: To evaluate the in vitro immunomodulation capacity of various non-pathogenic yeast strains and to investigate the ability of some of these food grade yeasts to prevent experimental colitis in mice.METHODS: In vitro immunomodulation was assessed by measuring cytokines [interleukin (IL)-12p70,IL-10,tumor necrosis factor and interferon γ] released by human peripheral blood mononuclear cells after 24 h stimulation with 6 live yeast strains (Saccharomyces ssp.) and with bacterial reference strains.A murine model of acute 2-4-6-trinitrobenzene sulfonic acid (TNBS)-colitis was next used to evaluate the distinct prophylactic protective capacities of three yeast strains compared with the performance of prednisolone treatment.RESULTS: The six yeast strains all showed similar non-discriminating anti-inflammatory potential when tested on immunocompetent cells in vitro .However,although they exhibited similar colonization patterns in vivo ,some yeast strains showed significant anti-inflammatory activities in the TNBS-induced colitis model,whereas others had weaker or no preventive effect at all,as evidenced by colitis markers (body-weight loss,macroscopic and histological scores,myeloperoxidase activities and blood inflammatory markers).CONCLUSION: A careful selection of strains is required among the biodiversity of yeasts for specific clinical studies,including applications in inflammatory bowel disease and other therapeutic uses. | Benot Foligné Jo■lle Dewulf Pascal Vandekerckove Georges Pignède Bruno Pot | 2010 | World Journal of Gastroenterology2010，16，17： | 2 |
| 9 | 梨花女子大学 校园谷显示文摘"校园谷"项目场地紧邻一个更大的校园和南边的新村,复杂的场地环境要求建筑"大于基地"。建筑师以一种全球化的地景式设计策略将梨花大学校园的组织结构融入到城市中。"校园谷"与"运动带相结合,创造出新型地貌,以一系列方式影响着周围环境。运动带和校园谷一样是多重事物的结合体。它是进入梨花大学校园的新大门,是日常运动消闲的新去处,是年度节庆或盛典的举办地,还是名副其实的将大学带入城市的纽带。 | André Morin Luca Reale Gaёlle Lauriot-Prévost Frederico de Matteis | 2013 | 城市环境设计2013，，9： | 2 |
| 10 | Biosynthesis, function and metabolic engineering of plant volatile organic compounds显示文摘 | Natalia Dudareva Antje Klempien Jo?lle K. Muhlemann Ian Kaplan | 2013 | New Phytol2013，，1： | 2 |
| 11 | Couple and Family Treatments: Study Quality and Level of Evidence显示文摘 | Jo?lle Darwiche Yves Roten | 2015 | Fam. Proc2015，，： | 2 |
| 12 | ON THE NUMERICAL SOLUTION OF QUASILINEAR WAVE EQUATION WITH STRONG DISSIPATIVE TERM显示文摘The numerical solution for a type of quasilinear wave equation is studied.The three-level difference scheme for quasi-linear waver equation with strong dissipative term is constructed and the convergence is proved.The error of the difference solution is estimated.The theoretical results are controlled on a numerical example. | Aytekin Gülle | 2004 | Applied Mathematics and Mechanics(English Edition)2004，25，7： | 2 |
| 13 | Post-keratoplasty astigmatism management by relaxing incisions:a systematic review显示文摘Postoperative visual acuity can be limited by post-keratoplasty astigmatism,even with a clear corneal graft.Astigmatism management can be performed by selective suture removal,adjustment of sutures,optical correction,photorefractive procedures,wedge resection,intra-ocular lens implantation,intracorneal ring segments,relaxing incisions with or without compression sutures and repeated keratoplasty.Relaxing incisions can be made in the graft,graft-host interface or host cornea.Despite the unpredictability of the method because the flat and steep meridians are usually not orthogonal after penetrating keratoplasty,with asymmetric power distribution,all the studies showed an overall reduction of refractive,keratometric or topographic astigmatism,ranging from 30%to 72%with manual or femtosecond-assisted techniques.Most patients with astigmatism higher than 6 diopters had residual cylinder less than or equal to 3 diopters,which can be treated by laser excimer ablation or secondary intraocular lens implantation. | Gaëlle Ho Wang Yin Louis Hoffart | 2017 | Eye and Vision2017，4，1： | 2 |
| 14 | Pure Hydrocarbons:An Efficient Molecular Design Strategy for the Next Generation of Host Materials for Phosphorescent Organic Light-Emitting Diodes显示文摘CONSPECTUS:Fantastic progresses have been made since the discovery of phosphorescent organic light-emitting diodes(PhOLEDs)in 1998(Nature 1998,395,151).In the emissive layer of a PhOLED,a heavy-metal complex(emitter)is dispersed as a guest in an organic semiconductor(host)in order to harvest both singlet and triplet excitons.This host/guest technique is essential to reach highperformance PhOLEDs.Undoubtedly,designing high-efficiency host materials for red,green,and blue phosphors has been the main driving force of the field.Nowadays,the most efficient PhOLEDs report very high external quantum efficiency(EQE)above 27%for the three colors.The molecular design of these high-efficiency host materials is based on small functional units,which have a crucial role in the device performance.These functional units are constructed on the assembly of electron-rich and/or electron-poor molecular fragments(such as carbazole,phenylamine,phosphine oxide,oxadiazole,pyridine,sulfone,etc.),which allows to finely tune the molecular orbitals energy levels(HOMO and LUMO)and the mobility of the charge carriers(hole and electrons).However,these molecular fragments incorporate heteroatoms,which in turn increase the molecular design complexity and production cost of the target materials and also create potential instability in the device.Indeed,the fragile C−N,C−P,and C−S bonds of such heteroatom-based hosts are involved,in part,in the OLED instability.As the instability of OLEDs is one of the most important problem to address at the current stage of development,developing new generations of host materials,without heteroatoms,has appeared as an important challenge in the field.In recent years,this new generation of host materials,called Pure HydroCarbons(PHC),only incorporating carbon and hydrogen atoms,has drawn the attention of the scientific community.PHC host materials only contain benzene rings,one of the most robust and inert building unit,which are assemble with suitable linkages to adjust their energy levels.However,reaching high-performance PhOLEDs with PHC-based hosts has been a real challenge.In the present account,thanks to a structure−properties relationship study,we recount the history of PHC-based host materials for PhOLEDs from the first example published in 2005(Org.Lett.2005,7,5131),to the recent advances,which have shown that PHC hosts can overpass the performance of heteroatom-based hosts(Chem.Sci.2020,11,4887).Our group has contributed over the years to unravel the design principles of PHC hosts in order to improve the devices performance.In the light of recent results,PHC hosts now enter a new era and this work shows that the PHC design strategy is promising for the future development of OLED industry as a high-performance and low-cost option. | Cyril Poriel Joëlle Rault-Berthelot | 2022 | Accounts of Materials Research2022，3，3： | 2 |
| 15 | Urinary neutrophil gelatinase-associated lipocalin as biomarker in the differential diagnosis of impairment of kidney function in cirrhosis显示文摘 | Claudia Fagundes Marie-No?lle Pépin Mónica Guevara Rogelio Barreto Gregori Casals Elsa Solà Gustavo Pereira Ezequiel Rodríguez Elisabet Garcia Verónica Prado Esteban Poch Wladimiro Jiménez Javier Fernández Vicente Arroyo Pere Ginès | 2012 | Journal of Hepatology2012，，2： | 2 |
| 16 | Analysis of active vibration control in smart structures by ANSYS显示文摘 | KARAG(U)LLE H MALGACA L (O)KTERN H F | 2004 | Smart Materials and Structure2004，13，： | 1 |
| 17 | Tum or ab lation with radiofrequency energy 显示文摘 | Gaze lle GS Go ldbe rg SN Solb ia tiL | 2000 | Radio logy2000，217，： | 1 |
| 18 | Virtual Reality of the Lower Urinary Tract in Women显示文摘 | A. Stenzl D. K?lle R. Eder A. St?ger R. Frank G. Bartsch | 1999 | International Urogynecology Journal1999，，4： | 1 |
| 19 | Heat flow estimation through inverted non integer identification models 显示文摘 | Battaglia J L Lay LLe Batsale J-C | 2000 | International Journal of Thermal Science2000，39，3： | 1 |
| 20 | Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil 显示文摘 | Rabφlle M Spliid N H | 2000 | Chemosphere2000，40，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员