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| 1 | Nestin in gastrointestinal and other cancers: Effects on cells and tumor angiogenesis显示文摘Nestin is a class Ⅵ intermediate filament protein that was originally described as a neuronal stem cell marker during central nervous system (CNS) development, and is currently widely used in that capacity. Nestin is also expressed in non-neuronal immature or progenitor cells in normal tissues. Under pathological conditions, nestin is expressed in repair processes in the CNS, muscle, liver, and infarcted myocardium. Furthermore, increased nestin expression has been reported in various tumor cells, including CNS tumors, gastrointestinal stromal tumors, pancreatic cancer, prostate cancer, breast cancer, malignant melanoma, dermatofibrosarcoma protuberances, and thyroid tumors. Nestin is reported to correlate with aggressive growth, metastasis, and poor prognosis in some tumors; however, the roles of nestin in cancer cells have not been well characterized. Furthermore, nestin is more specifically expressed in proliferating small-sized tumor vessels in glioblastoma and gastric, colorectal, and prostate cancers than are other tumor vessel markers. These findings indicate that nestin may be a marker for newly synthesized tumor vessels and a therapeutic target for tumor angiogenesis. It has received a lot of attention recently as a cancer stem cell marker in various cancer cells including brain tumors, malignant rhabdoid tumors, and uterine, cervical, prostate, bladder, head and neck, ovarian, testicular, and pancreatic cancers. The purpose of this review is to clarify the roles of nestin in cancer cells and in tumor angiogenesis, and to examine the association between nestin and cancer stem cells. Nestin has the potential to serve as a molecular target for cancers with nestin-positive cancer cells and nestin-positive tumor vasculature. | Toshiyuki Ishiwata Yoko Matsuda Zenya Naito | 2011 | World Journal of Gastroenterology2011，17，4： | 11 |
| 2 | The inertia properties of Cs 2 LiYCl 6 : Ce scintillation crystals显示文摘 | L. Trefilova V. Cherginets A. Gektin B. Grinyov V. Alekseev I. Golub N. Kosinov A. Litichevsky T. Ponomarenko O. Zelenskaya I. Zenya | 2007 | Radiation Measurements2007，，： | 1 |
| 3 | Risk factors for a poor outcome following surgical treatment of cervical spondylotic amyotrophy: a multicenter study显示文摘 | Ryoji Tauchi Shiro Imagama Hidefumi Inoh Yasutsugu Yukawa Tokumi Kanemura Koji Sato Yuji Matsubara Atsushi Harada Yudo Hachiya Mistuhiro Kamiya Hisatake Yoshihara Zenya Ito Kei Ando Naoki Ishiguro | 2013 | European Spine Journal2013，，1： | 1 |
| 4 | The contribution of phospholipase A2 to the cochlear dysfunction induced by transient ischemia显示文摘 | Keiji Tabuchi Zenya Ito Shigeki Tsuji Tetsuro Wada Kazuhiko Takahashi Akira Hara Tetsuro Wada KazuhikoTakahashi Akira Hara Jun Kusakari | | Hearing Research0，20，： | 1 |
| 5 | Myoepithelial hamartoma of the small bowel: Report of a case显示文摘 | Noritake Tanaka Tomoko Seya Masahiko Onda Yoshikazu Kanazawa Zenya Naitoh Goro Asano Kunihiko Hao | 1996 | Surgery Today1996，，12： | 1 |
| 6 | Bone union rate with autolo- gnus iliac bone versus local bone graft in posterior lumbar interbody fusion 显示文摘 | Zenya I Yukihil o M Yoshihito S | 2010 | Spine2010，35，21： | 1 |
| 7 | CT, MRI, and PET findings of gastric schwannoma显示文摘 | Minako Takeda Yasuo Amano Tadashi Machida Shunji Kato Zenya Naito Shinichiro Kumita | 2012 | Japanese Journal of Radiology2012，，7： | 1 |
| 8 | Is Decompressive Surgery Effective for Spinal Cord Sarcoidosis Accompanied With Compressive Cervical Myelopathy?显示文摘 | Yoshihito Sakai Yukihiro Matsuyama Shiro Imagama Zenya Ito Norimitsu Wakao Naoki Ishiguro Hirohisa Watanabe Fumihiko Kato Yasutsugu Yukawa Keigo Ito Kazuhiro Suzuki Akiko Tsuboi Tokumi Kanemura Go Yoshida | 2010 | Spine2010，，23： | 1 |
| 9 | Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: A potential therapeutic target in colorectal cancer显示文摘 | Yoko Matsuda Toshiyuki Ishiwata Kazuya Yamahatsu Kiyoko Kawahara Masahito Hagio Wei-Xia Peng Tetsushi Yamamoto Nando Nakazawa Tomoko Seya Yoshiharu Ohaki Zenya Naito | 2011 | Cancer Letters2011，，2： | 1 |
| 10 | Expression of hsp90 and cyclinD1 in human breast cancer显示文摘 | Zenya N Munenori Y | 1999 | Cancer Letters1999，137，1： | 1 |
| 11 | Multicentric pancreatic intraepithelial neoplasias (PanINs) presenting with the clinical features of chronic pancreatitis显示文摘 | Takayuki Aimoto Eiji Uchida Yoshiharu Nakamura Akira Matsushita Akira Katsuno Kazumitsu Chou Masao Kawamoto Zenya Naito Takashi Tajiri | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，5： | 1 |
| 12 | Expression of Cathepsin B and Cystatin C in Human Breast Cancer显示文摘 | Masao Yano Kyoji Hirai Zenya Naito Munenori Yokoyama Toshiyuki Ishiwata Yasuo Shiraki Masataka Inokuchi Goro Asano | 2001 | Surgery Today2001，，5： | 1 |
| 13 | Changes to levels of serum neuron-specific enolase in a patient with small cell carcinoma of the pancreas显示文摘 | Yoshiharu Nakamura Takashi Tajiri Eiji Uchida Yasuo Arima Takayuki Aimoto Akira Katsuno Zenya Naito | 2005 | Journal of Hepato-Biliary-Pancreatic Surgery2005，，1： | 1 |
| 14 | Correlation of hypoxia inducible factor-1α with lymphatic metastasis via vascular endothelial growth factor-C in human esophageal cancer显示文摘 | Miwako Katsuta Masao Miyashita Hiroshi Makino Tsutomu Nomura Seiichi Shinji Kiyohiko Yamashita Takashi Tajiri Mitsuhiro Kudo Toshiyuki Ishiwata Zenya Naito | 2004 | Experimental and Molecular Pathology2004，，2： | 1 |
| 15 | Complete response of a patient with advanced gastric cancer, showing Epstein-Barr virus infection, to preoperative chemotherapy with S-1 and cisplatin显示文摘 | Tomoko Seya Noritake Tanaka Kimiyoshi Yokoi Noriyuki Ishikawa Koji Horiba Yoshikazu Kanazawa Takeshi Yamada Michihiro Koizumi Seiichi Shinji Hirotake Okazaki Yoshiharu Ohaki Toshiyuki Ishiwata Zenya Naito Takashi Tajiri | 2007 | International Journal of Clinical Oncology2007，，6： | 1 |
| 16 | The contribution of phospholipase A2 to the cochlear dysfunction induced by transient ischemia 显示文摘 | Keiji Tabuchi Zenya Ito Shigeki Tsuji | 2000 | Hearing Research2000，144，： | 1 |
| 17 | The contribution of phospholipase A2 to the cochlear dysfunction induced by transient ischemia 显示文摘 | Keiji T Zenya I Shigeki T | 2000 | Hearing Research2000，144，1： | 1 |
| 18 | Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti -human CYP2E1 antibody显示文摘 | Yoichiro Hirose Zenya Naito Shunji Kato | 2002 | J Nippon Med Sch2002，69，3： | 1 |
| 19 | Volumetric change in interbody bone graft after posterior lumbar interbody fusion (PLIF) : a prospective study 显示文摘 | Zenya I Shiro I Tokumi K | 2014 | Eur Spine J2014，23，10： | 1 |
| 20 | Design Knowledge and Software Engineering显示文摘This paper points out various relationships between Design Knowledge and Software Engineering. After introduction of human design, the relationships between industrial Software Engineering is discussed, then further details of human design knowledge are revealed with discussions on humanistic aspects of design. | Zenya Koono, Hui Chen, Hassan Abolhassani, Behrouz H.Far Saitama University, 255 Shimo okubo Urawa,Saitama 338 8570, Japan | 2001 | Wuhan University Journal of Natural Sciences2001，6，Z1： | 0 |
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