|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of phosphorus fluctuation caused by river water dilution in eutrophic lake on competition between blue-green alga Microcystis aeruginosa and diatom Cyclotella sp.显示文摘Tega-numa (Lake Tega) is one of the eutrophic lakes in Japan. For the improvement of water quality in Lake Tega, the North-chiba Water Conveyance Channel was constructed in 2000, which transfer water from Tone River into the lake. After 2000, the dominant species of diatoms, mainly Cyclotella sp., have been replacing blue-green algae, mainly Microcystis aeruginosa in Lake Tega. This transition of dominant species would be due to the dilution, but the detail mechanism has not been understood yet. This study examined the relationship between phosphorus fluctuation caused by river water dilution to Lake Tega and dominance of algal species, M. aeruginosa or Cyclotella sp. based on the single-species and the mixed-species culture experiments. The single-species culture experiment showed that the half-saturation constant and uptake rate of phosphorus were one order lower and seven times higher for M. aeruginosa than those for Cyclotella sp. These findings implied that M. aeruginosa would possess a potential for the growth and survival over Cyclotella sp. in the phosphorus limited condition. The superiority of M. aeruginosa was reflected in the outcome of the mixed-species culture experiment, i.e., dominance of M. aeruginosa, even phosphorus concentration was lowered to 0.01 mg-P/L. Therefore, it could be concluded that the decrease in phosphorus concentration due to the river water dilution to Lake Tega would be interpreted as a minor factor for the transition of dominant species from M. aeruginosa to Cyclotella sp. | Yoshimasa Amano Yusuke Sakai Takumi Sekiya Kimitaka Takeya Kazuo Taki Motoi Machida | 2010 | Journal of Environmental Sciences2010，22，11： | 16 |
| 2 | Reactive lymphoid hyperplasia of the liver:A case report and review of literature显示文摘有反应淋巴的增生(RLH ) 的一个 53 岁的女病人的一个盒子,肝的临床上指明的同样假的淋巴瘤在这篇文章被描述。病人为顺便说一下在另一所医院发现的肝的肿瘤的进一步的评估进入我们的医院。各种各样的诊断方法,包括的 ultrasonography (美国) ,计算机化的断层摄影术(CT ) ,磁性的回声成像(MRI ) 和肝的血管造影术与与肝细胞癌(HCC ) 一致的突出的调查结果在肝显示了三小损害。外科的切除术被执行,三损害是作为肝的 RLH 诊断的用显微镜。损害与滤泡和 hyalinized 包括了淋巴样细胞的巨大的渗入内部小囊的空格。Immunohistochemical 检查表明渗透的淋巴细胞没有突出的原子非典型和 polyclonality。肝的 RLH 是一个很稀罕的条件,仅仅 12 个案例在英语文学被报导了。报导案例的多数是中年的女人并且关于他们的一半有象自体免疫的甲状腺炎那样的一些免疫逻辑畸形, Sjogren 的症候群,主要免疫不全,主要胆汁性肝硬变。因为他们临床上经常作为 HCC 被误诊,外科是为这些病人的治疗的选择。尽管他们的病理类似于恶性淋巴瘤,临床的功课是完全良性的。作者建议肝的 RLH 能被它的临床的特征从 HCC 区别。 | Takuro Machida Toshiyuki Takahashi Tomoo Itoh Michiaki Hirayama Takayuki Morita Shoichi Horita | 2007 | World Journal of Gastroenterology2007，13，40： | 13 |
| 3 | 烧结工艺使用气体燃料喷入技术减少CO_2排放显示文摘JFE钢铁公司开发了在烧结矿表面喷入含氢的气体燃料技术,可不增加焦粉配比,提高烧结矿质量。使用该技术,含氢气体可部分替代焦粉,使1200~1400℃的燃烧层变宽成为可能。通过X射线对多孔状的烧结饼进行CT检查与烧结锅试验,从理论到实践都证明了喷入燃料气体技术的使用效果。保持1200~1400℃的温度带,为生产高强度、高还原性的烧结矿至关重要,它能使合适的温度带变宽、液相率增加、提高1~5mm孔隙间的熔合并提升烧结矿强度。大于5mm的孔隙的烧结矿数量增多提高了料层的透气性,低温烧结工艺也抑制了铁矿石的自身熔化。而在未熔化的铁矿石中,小于1μm的微孔隙的存在也使烧结矿的还原性提高,从而改善烧结饼的孔隙结构,提高烧结矿质量。2009年1月,京浜1号烧结机应用了该技术,到目前为止工况稳定。结果,烧结工序的能源利用率大幅提升,减排CO2约6万t/a。 | Nobuyuki Oyama Yuji Iwami Satoshi Machida Takahide Higuchi Tetsuya Yamamoto Yushinori Watanabe Michitaka Sato Kanji Takeda Masakata Shimizu Koki Nishioka 何海良 | 2013 | 世界钢铁2013，，1： | 11 |
| 4 | Synthesis and luminescent properties of low oxygen contained Eu^(2+)-doped Ca-α-SiAlON phosphor from calcium cyanamide reduction显示文摘A new convenient calcium cyanamide (CaCN2) reduction route was developed to synthesize the Eu2+ activated Ca-α-SiAlON phosphors containing low oxygen content. The luminescence properties of the obtained products were investigated for white LEDs applica- tion. The critical Eu2+ concentration in various hosts and its effect on the photoluminescence properties were studied. The optimized sample (10at.% Eu2+ vs. Ca2+) could be efficiently excited by the current GaN/InGaN blue LED chips and provided emission intensity competitive with that of YAG:Ce3+ (P46-Y3) standard, revealing that this phosphor was a potential candidate for phosphor-converted white LEDs. | PIAO Xianqing Ken-ichi Machida Takashi Horikawa Hiromasa Hanzawa | 2008 | Journal of Rare Earths2008，26，2： | 7 |
| 5 | Crystal Structure of Arabidopsis thaliana Dawdle Forkhead-Associated Domain Reveals a Conserved Phospho-Threonine Recognition Cleft for Dicer-Like 1 Binding显示文摘游荡(DDL ) 是为 Arabidopsis 的发展处理蛋白质必需品的 microRNA。DDL 包含一个通常认为的原子本地化信号在它的氨基终点、联系 forkhead (联邦住房管理局) 在 carboxyl-terminus.Here 的领域,我们报导 Arabidopsis 的 FHA 领域的水晶结构游荡,在 1.7- 由多重波长的异常分散方法决定了吗?分辨率。DDL 联邦住房管理局结构显示包含包括二长反平行的海滨的一个唯一的结构的主题的 seven-stranded-sandwich 体系结构。惊人地, DDL 联邦住房管理局领域的 crystalpacking 揭示那从对称相关的 DDL 联邦住房管理局领域的 glutamate 残余,结构的 mimicof phospho-threonine,被保存 phospho-threonine 绑定劈开的在结构上明确地认出。Consistentlywith 结构的观察,在 Nicotiana benthamiana 执行的 co-immuno-precipitation 实验证明有 DCL1 的 DDL 联邦住房管理局领域 co-immuno-precipitates 碎裂包含预言的 pThr+3 (Ile/Val/Leu/Asp ) 主题。一起拿,我们数由正规绑定的残余 DDL 联邦住房管理局 domainas 劈开的目标的识别安置联邦住房管理局的关键分子的事件在植物 miRNA processing.Key 词的调停域的 proteinprotein 相互作用: | Satoru Machida | 2013 | Molecular Plant2013，6，4： | 6 |
| 6 | 绿色溶剂γ-戊内酯中果糖催化转化为5-羟甲基糠醛显示文摘通过生物质衍生糖的酸催化转化制备生物质基平台化合物5-羟甲基糠醛受到关注。常用又有效的溶剂包括离子液体和二甲基亚砜等,但这些溶剂黏度高,易造成空气污染。以γ-戊内酯作为溶剂,研究果糖催化转化为5-羟甲基糠醛的绿色过程,系统研究酸催化剂种类、反应温度、催化剂用量、果糖初始浓度及底物种类等对5-羟甲基糠醛产率的影响。通过反应条件的优化,以HCl溶液为催化剂,在果糖初始质量浓度2%、反应温度100℃和反应时间30 min条件下,5-羟甲基糠醛产率为93.5%。5-羟甲基糠醛产率随果糖初始添加量的增加而呈下降趋势,但果糖初始质量浓度为10%时,5-羟甲基糠醛产率仍保持约90%,表明γ-戊内酯是一种将果糖催化转化为5-羟甲基糠醛的优良绿色溶剂。 | 刘念 漆新华 Hiroshi Machida | 2015 | 工业催化2015，23，8： | 5 |
| 7 | Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese显示文摘AIM: To examine an association between the cytotoxic T-lymphocyte antigen 4 (CTLA4) gene that plays a role in downregulation of T-cell activation and inflammatory bowel disease consisting of ulcerative colitis (UC) and Crohn's disease (CD) in the Japanese.METHODS: We studied 108 patients with UC, 79 patients with CD, and 200 sex-matched healthy controls, with respect to three single nucleotide polymorphisms (SNPs)in CTLA4, such as C-318T in the promoter region, A+49G in exon 1 and G+6230A in the 3' untranslated region (3'-UTR) by a PCR-restriction fragment length polymorphism method, and to an (AT)n repeat polymorphism in 3'-UTR by fragment analysis with fluorescence-labeling on denaturing sequence gels. Frequency of alleles and genotypes and their distribution were compared statistically between patients and controls and among subgroups of patients, using χ2 and Fisher exact tests.RESULTS: The frequency of 'A/A' genotype at the G+6230A SNP site was statistically lower in UC patients than in controls (3.7% vs 11.0%, P= 0.047, odds ratio (OR) = 0.311). Moreover, the frequency of'G/G' genotype at the A+49G SNP site was significantly higher in CD patients with fistula (48.6%) than those without it (26.2%)(P = 0.0388, OR=2.67).CONCLUSION: The results suggest that CTLA4 located at 2q33 is a determinant of UC and responsible for fistula formation in CD in the Japanese. | Haruhisa Machida Kazuhiro Tsukamoto Chun-Yang Wen Yukiko Narumi Saburou Shikuwa Hajime Isomoto Fuminao Takeshima Yohei Mizuta Norio Niikawa Ikuo Murata Shigeru Kohno | 2005 | World Journal of Gastroenterology2005，11，27： | 4 |
| 8 | Narrow-Band Imaging in the Diagnosis of Colorectal Mucosal Lesions: A Pilot Study显示文摘 | H. Machida Y. Sano Y. Hamamoto M. Muto T. Kozu H. Tajiri S. Yoshida | 2004 | Endoscopy2004，，12： | 4 |
| 9 | Recycle for Sludge Scrap of Nd-Fe-B Sintered Magnet as Isotropic Bonded Magnet显示文摘The reduction diffusion method was performed for the sludge scrap of Nd-Fe-B sintered magnets with adding Ca metal to recover the oxidized Nd-Fe-B phase. After washing the resultant powders to remove Ca metal component, the powders obtained were recycled as an isotropic magnetic powder by the melt spinning method. The magnetic properties of powders as recycled were inferior, especially for the coercivity value, due to the deletion of rare earth metals during the washing process. The adjustment of metal composition, i.e., the addition of Nd metal, at the melt spinning process improved the magnetic properties to be B r=~0.75 T, H cj=~0.93 mA·m -1, and (BH) max=~91 kJ·m -3. The magnetic properties of the bonded magnets prepared from the composition-adjusted powders were B r=~0.66 T, H cj=~0.92 mA·m -1, and (BH) max=~70 kJ·m -3, which are approximately comparable to the commercially available MQPB boned one (B r=~0.73 T, H cj=~0.79 mA·m -1, and (BH) max=~86 kJ·m -3). | Masahiro Itoh Masahiro Masuda Shunji Suzuki Ken-ichi Machida | 2004 | Journal of Rare Earths2004，22，1： | 4 |
| 10 | Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene显示文摘AIM: To investigate the frequency and distribution of N-acetyltransferase 2 (NAT2) and uridine 5′-diphosphate (UDP)-glucuronosyltransferase 1A7 (UGT1A7) genes in patients with ulcerative colitis (UC) and Crohn's disease (CD).METHODS: Frequencies and distributions of NAT2 and UGT1A7SNPs as well as their haplotypes were investigated in 95 patients with UC, 60 patients with CD, and 200gender-matched, unrelated, healthy, control volunteers by PCR-restriction fragment length polymorphism (RFLP),PCR-denaturing high-performance liquid chromatography (DHPLC), and direct DNA sequencing.RESULTS: Multiple logistic regression analysis revealed that the frequency of haplotype, NAT2*7B, significantly increased in CD patients, compared to that in controls (P= 0.0130, OR = 2.802, 95%CI = 1.243-6.316). However,there was no association between NAT2 haplotypes and UC, or between any UGT1A7haplotypes and inflammatory bowel disease (IBD).CONCLUSION: It is likely that the NAT2 gene is one of the determinants for CD in Japanese. Alternatively, a new CD determinant may exist in the 8p22 region, whereNAT2is located. | Haruhisa Machida Kazuhiro Tsukamoto Chun-Yang Wen Saburou Shikuwa Hajime Isomoto Yohei Mizuta Fuminao Takeshima Kunihiko Murase Naomichi Matsumoto Ikuo Murata Shigeru Kohno Chen-Yang Wen | 2005 | World Journal of Gastroenterology2005，11，31： | 3 |
| 11 | Penetration profile of chloride ion in cracked reinforced concrete显示文摘 | Pa Pa Win Makiko Watanabe Atsuhiko Machida | 2003 | Cement and Concrete Research2003，，7： | 3 |
| 12 | Tumor characteristics of ductal carcinoma in situ of breast visualized on [F-18] fluorodeoxyglucose-positron emission tomography/computed tomography: Results from a retrospective study显示文摘AIM To clarify clinicopathological features of ductal carcinoma in situ(DCIS) visualized on [F-18] fluorodeoxyglucosepositron emission tomography/computed tomography(FDG-PET/CT).METHODS This study retrospectively reviewed 52 consecutive tumors in 50 patients with pathologically proven pure DCIS who underwent [F-18] FDG-PET/CT before surgery. [F-18] FDG-PET/CT was performed after biopsy in all patients. The mean interval from biopsy to [F-18] FDGPET/CT was 29.2 d. [F-18] FDG uptake by visual analysis and maximum standardized uptake value(SUVmax) was compared with clinicopathological characteristics.RESULTS[F-18] FDG uptake was visualized in 28 lesions(53.8%) and the mean and standard deviation of SUVmax was 1.63 and 0.90. On univariate analysis, visual analysis and the SUVmax were associated with symptomatic presentation(P = 0.012 and 0.002, respectively), palpability(P = 0.030 and 0.024, respectively), use of core-needle biopsy(CNB)(P = 0.023 and 0.012, respectively), ultrasound-guided biopsy(P = 0.040 and 0.006, respectively), enhancing lesion ≥ 20 mm on magnetic resonance imaging(MRI)(P = 0.001 and 0.010, respectively), tumor size ≥ 20 mm on histopathology(P = 0.002 and 0.008, respectively). However, [F-18] FDG uptake parameters were not significantly associated with age, presence of calcification on mammography, mass formation on MRI, presence of comedo necrosis, hormone status(estrogen receptor, progesterone receptor and human epidermal growth factor receptor-2), and nuclear grade. The factors significantly associated with visual analysis and SUVmax were symptomatic presentation(P = 0.019 and 0.001, respectively), use of CNB(P = 0.001 and 0.031, respectively), and enhancing lesion ≥ 20 mm on MRI(P = 0.001 and 0.049, respectively) on multivariate analysis.CONCLUSION Although DCIS of breast is generally non-avid tumor, symptomatic and large tumors(≥ 20 mm) tend to be visualized on [F-18] FDG-PET/CT. | Tomoyuki Fujioka Kazunori Kubota Akira Toriihara Youichi Machida Kaori Okazawa Tsuyoshi Nakagawa Yukihisa Saida Ukihide Tateishi | 2016 | World Journal of Radiology2016，8，8： | 2 |
| 13 | Pathological response measured using virtual microscopic slides for gastric cancer patients who underwent neoadjuvant chemotherapy显示文摘BACKGROUND Although pathological response is a common endpoint used to assess the efficacy of neoadjuvant chemotherapy (NAC) for gastric cancer, the problem of a low rate of concordance from evaluations among pathologists remains unresolved. Moreover, there is no globally accepted consensus regarding the optimal evaluation. A previous study based on a clinical trial suggested that pathological response measured using digitally captured virtual microscopic slides predicted patients’ survival well. However, the pathological concordance rate of this approach and its usefulness in clinical practice were unknown. AIM To investigate the prognostic utility of pathological response measured using digital microscopic slides in clinical practice. METHODS We retrospectively evaluated pathological specimens of gastric cancer patients who underwent NAC followed by surgery and achieved R0 resection between March 2009 and May 2015. Residual tumor area and primary tumor beds were measured in one captured image slide, which contained the largest diameter of the resected specimens. We classified patients with < 10% residual tumor relative to the primary tumorous area as responders, and the rest as non-responders;we then compared overall survival (OS) and relapse-free survival (RFS) between these two groups. Next, we compared the prognostic utility of this method using conventional Japanese criteria. RESULTS Fifty-four patients were evaluated. The concordance rate between two evaluators was 96.2%. Median RFS of 25 responders and 29 non-responders was not reached (NR) vs 18.2 mo [hazard ratio (HR)= 0.35, P = 0.023], and median OS was NR vs 40.7 mo (HR = 0.3, P = 0.016), respectively. This prognostic value was statistically significant even after adjustment for age, eastern cooperative oncology group performance status, macroscopic type, reason for NAC, and T- and Nclassification (HR = 0.23, P = 0.018). This result was also observed even in subgroup analyses for different macroscopic types (Borrmann type 4/non-type 4) and histological types (differentiated/undifferentiated). Moreover, the adjusted HR for OS between responders and non-responders was lower in this method than that in the conventional histological evaluation of Japanese Classification of Gastric Carcinoma criteria (0.23 vs 0.39, respectively). CONCLUSION The measurement of pathological response using digitally captured virtual microscopic slides may be useful in clinical practice. | Sadayuki Kawai Tadakazu Shimoda Takashi Nakajima Masanori Terashima Katsuhiro Omae Nozomu Machida Hirofumi Yasui | 2019 | World Journal of Gastroenterology2019，25，35： | 2 |
| 14 | A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding显示文摘 | Natsuhiko Kameda Kazuhide Higuchi Masatsugu Shiba Hirohisa Machida Hirotoshi Okazaki Hirokazu Yamagami Tetsuya Tanigawa Kenji Watanabe Toshio Watanabe Kazunari Tominaga Yasuhiro Fujiwara Nobuhide Oshitani Tetsuo Arakawa | 2008 | Journal of Gastroenterology2008，，6： | 2 |
| 15 | Successful treatment of giant rectal varices by modified percutaneous transhepatic obliteration with sclerosant:Report of a case显示文摘We present a female patient with continuous melena, diagnosed with rectal variceal bleeding. She had a history of esophageal varices, which were treated with endoscopic therapy. Five years after the treatment of esophageal varices, continuous melena occurred. Since colonoscopy showed that the melena was caused by giant rectal varices, we thought that they were not suitable to receive endoscopic treatment. We chose the modified percutaneous transhepatic obliteration with sclerosant, which is one of the interventional radiology techniques but a new clinical procedure for rectal varices. After the patient received this therapy, her condition of rectal varices was markedly improved. | Hirotoshi Okazaki Kazuhide Higuchi Masatsugu Shiba Shirou Nakamura Tomoko Wada Kazuki Yamamori Ai Machida Kaori Kadouchi Akihiro Tamori Kazunari Tominaga Toshio Watanabe Yasuhiro Fujiwara Kenji Nakamura Tetsuo Arakawa | 2006 | World Journal of Gastroenterology2006，12，33： | 2 |
| 16 | Small Bowel Injury by Low-Dose Enteric-Coated Aspirin and Treatment With Misoprostol: A Pilot Study显示文摘 | Toshio Watanabe Satoshi Sugimori Natsuhiko Kameda Hirohisa Machida Hirotoshi Okazaki Tetsuya Tanigawa Kenji Watanabe Kazunari Tominaga Yasuhiro Fujiwara Nobuhide Oshitani Kazuhide Higuchi Tetsuo Arakawa | 2008 | Clinical Gastroenterology and Hepatology2008，，11： | 2 |
| 17 | Phase 1 study of efatutazone, a novel oral peroxisome proliferator-activated receptor gamma agonist, in combination with FOLFIRI as second-line therapy in patients with metastatic colorectal cancer显示文摘 | Yoshito Komatsu Takayuki Yoshino Kentaro Yamazaki Satoshi Yuki Nozomu Machida Takahide Sasaki Ichinosuke Hyodo Yutaka Yachi Hiroshi Onuma Atsushi Ohtsu | 2014 | Investigational New Drugs2014，，3： | 2 |
| 18 | Risk factors predictive of lymph node metastasis in depressed early gastric cancer显示文摘 | Nobutsugu Abe Takashi Watanabe Kazufumi Suzuki Hiromichi Machida Hiroshi Toda Yuzo Nakaya Tadahiko Masaki Toshiyuki Mori Masanori Sugiyama Yutaka Atomi | 2002 | The American Journal of Surgery2002，，2： | 2 |
| 19 | Penetration profile of chloride ion in cracked reinforced concrete显示文摘 | Pa Pa Win Makiko Watanabe Atsuhiko Machida | 2003 | Cement and Concrete Research2003，，7： | 2 |
| 20 | Catalytic properties of BaMA11O19(M=Cr, Mn, Fe, Ni) for high temperature catalytic combustion显示文摘 | Machida M Eguchi K Arai H | 1989 | Journal of Catalysis1989，，120： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员