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| 1 | Fulminant phlegmonitis of the esophagus, stomach,and duodenum due to Bacillus thuringiensis显示文摘We report a case of phlegmonitis of the esophagus, stomach, and duodenum in patient in an immunocompromised state. Culture of gastric juice and blood yielded Bacillus thuringiensis. This case showed that even low-virulence bacilli can cause lethal gastrointestinalphlegmonous gastritis in conditions of immunodeficiency. | Hisatake Matsumoto Hiroshi Ogura Masafumi Seki Mitsuo Ohnishi Takeshi Shimazu | 2015 | World Journal of Gastroenterology2015，21，12： | 3 |
| 2 | 蝶豆花提取物的抗氧化活性及其对酮康唑诱导大鼠睾丸损伤的保护作用(英文)显示文摘研究目的:研究蝶豆花提取物的抗氧化活性及其对酮康唑(KET)诱导雄性大鼠睾丸损伤的保护作用。创新要点:对蝶豆花提取物保护酮康唑引起的雄性动物睾丸损伤进行研究,为减轻抗真菌药物酮康唑的生殖毒性提供理论依据和解决途径。研究方法:采用2,2-二苯基-1-苦肼基自由基(DPPH)分析法和亚铁还原能力实验法(FRAP)来测定蝶豆花提取物的抗氧化活性。在为期28天的动物试验中,前21天为预防期,第21至28天为KET诱导期。整个试验期中,对雄性大鼠进行蝶豆花提取物(0、50、100 mg/kg BW)灌胃饲养;在诱导期,同时腹腔注射KET(100 mg/kg BW)。试验结束后,测定睾丸、附睾和输精管以及精囊的重量、血清睾酮水平、精子浓度、组织结构、睾丸的直径和睾丸酪氨酸磷酸化水平。重要结论:蝶豆花提取物具有清除DPPH自由基能力和较高的还原能力,其在100 mg/kg BW下对雄性大鼠生殖系统无毒。50、100 mg/kg BW蝶豆花提取物能改善KET引起的生殖器官重量下降、血清睾酮水平和精子浓度,降低KET引起的睾丸损伤。与其他组相比,100 mg/kg BW蝶豆花提取物能显著提高睾丸中50-kDa的酪氨酸磷酸化蛋白的表达。由此可见,具有抗氧化活性的蝶豆花提取物不会损伤雄性生殖系统,而且具有保护KET诱导大鼠睾丸损伤的作用。 | Sitthichai IAMSAARD Jaturon BURAWAT Pipatpong KANLA Supatcharee ARUN Wannisa SUKHORUM Bungorn SRIPANIDKULCHAI Nongnut UABUNDIT Jintanaporn WATTATHORN Wiphawi HIPKAEO Duriya FONGMOON Hisatake KONDO | 2014 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2014，15，6： | 2 |
| 3 | Muhivisceral and isolat- ed intestinal procurement techniques 显示文摘 | Yersiz H Renz JF Hisatake GM | 2003 | Liver Transpl2003，9，8： | 1 |
| 4 | The Rpb6 subunit of fission yeast RNA polymerase Ⅱ is a contact target of the transcription elongation factor TFIIS显示文摘 | Ishiguro A Nogi Y Hisatake K | | 0，，04： | 1 |
| 5 | PC-SPES: a unique inhibitor of proliferation of prostate cancer cells in vitro and in vivo显示文摘 | Kubota T Hisatake J Hisatake Y | 2000 | Prostate2000，42，3： | 1 |
| 6 | Effects of pipe roof supportsand the excavation method on the displacements above atunnel face显示文摘 | HISATAKE M OHNO S | 2008 | Tunnelling and Underground SpaceTechnology2008，23，2： | 1 |
| 7 | Utility of delayed gadolinium-enhanced MRI (dGEMRIC) for qualitative evaluation of articular cartilage of patellofemoral joint显示文摘 | Takehiro Nojiri Nobuyoshi Watanabe Takehiko Namura Wataru Narita Kazuya Ikoma Takehiko Suginoshita Hisatake Takamiya Hiroto Komiyama Hirotoshi Ito Tsunehiko Nishimura Toshikazu Kubo | 2006 | Knee Surgery Sports Traumatology Arthroscopy2006，，8： | 1 |
| 8 | Effects of pipe roof supports and the excavation method on the displacements above a tunnel face显示文摘 | HISATAKE M OHNO S | 2008 | Tunnelling and Underground Space Technology2008，23，2： | 1 |
| 9 | 显示文摘 | Kainuma S Takayanagi K Hisatake K | 2002 | Journal of Magnetism and Magnetic Materials2002，246，： | 1 |
| 10 | MR T2 Image classifi- cation in cervical compression myelopathy predictor of surgical out- come 显示文摘 | Yasutsugu Y Fumihiko K Hisatake Y | 2007 | Spine2007，32，15： | 1 |
| 11 | Osteointegration of dental implants in rabbit bone with low mineral density显示文摘 | Hisatake M Masato M Yoichi K | 1997 | J Oral Maxillofac Surg1997，55，4： | 1 |
| 12 | Effects of pipe roof sup-ports and the excavation method on the displacementsabove a tunnel face显示文摘 | HISATAKE M OHNO S | 2008 | Tunnelling and UndergroundSpace Technology2008，23，2： | 1 |
| 13 | Lin-ear time-to-space mapping system using double elec- trooptic beam deflectors显示文摘 | HISATAKE S TADA K NAGATSUMA T | 2008 | Optics Express2008，16，26： | 1 |
| 14 | Speciation of antimony( Ⅲ ) and antimony(V) using hydride generation inductively coupled plasma atomicemission spectrometry combined with the rate of pre-reduction of antimony显示文摘 | Feng Y L Hisatake N Chen H Y | 1999 | Analytica Chimica Acta1999，386，： | 1 |
| 15 | Effects of the ring-cut excavation method on the restraint of displacements ahead of a tunnel face显示文摘 | Hisatake M Ohno S Katayama T | 2009 | Tunnelling and Underground Space Technology2009，24，： | 1 |
| 16 | Novel vitamin D(3) analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D(3),that modulates cell growth, differentiation, apoptosis, cell cycle,and induction of PTEN in leukemic cells显示文摘 | HISATAKE J O'KELLY J USKOKOVIC MR | 2001 | Blood2001，97，8： | 1 |
| 17 | Surgical outcome of ossification of the posterior longitudinal ligament (OPLL) of the thoracic spine显示文摘 | Yukihiro Matsuyama Hisatake Yoshihara Taichi Tsuji | 2005 | Spinal Disord Tech2005，18，： | 1 |
| 18 | Giant magnetoresistance and particle size distribution in pulse-plated Co-Cu granular films显示文摘 | KAINNUMA S TAKAYANAGI K HISATAKE K WATANABE T | 2002 | Journal of Magnetism and Magnetic Materials2002，246，： | 1 |
| 19 | Down regulation of prostate specificantigen expression by ligands for peroxisome proliferator activated receptorg in human prostate cancer显示文摘 | Hisatake J Ikezoe T Carey M | 2000 | Cancer Res2000，，60： | 1 |
| 20 | Risk factors for a poor outcome following surgical treatment of cervical spondylotic amyotrophy: a multicenter study显示文摘 | Ryoji Tauchi Shiro Imagama Hidefumi Inoh Yasutsugu Yukawa Tokumi Kanemura Koji Sato Yuji Matsubara Atsushi Harada Yudo Hachiya Mistuhiro Kamiya Hisatake Yoshihara Zenya Ito Kei Ando Naoki Ishiguro | 2013 | European Spine Journal2013，，1： | 1 |
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