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| 1 | 耐温耐盐疏水缔合聚丙烯酰胺合成方法及其展望显示文摘目前合成HAPAM的方法,主要可分为聚丙烯酰胺(PAM)的化学改性和PAM与其他疏水单体的共聚。共聚主要由非均相共聚、均相共聚和胶束共聚组成。除此以外还包括反相微乳液聚合法、超声波聚合法、无皂乳液聚合等方法。如何保证聚合物在油藏实际条件下仍具有良好的稳定性已经成为近年来聚合物驱的热点之一。对各类HAPAM的特点及适用条件进行了评价,此外还对氟碳型、孪尾型和超支化HAPAM进行了综述,对HAPAM未来的研究方向进行了展望。 | 潘一 冯俊楠 杨双春 ZAIN ULLAH ABDUL QAYUM 张海燕 | 2018 | 应用化工2018，47，8： | 13 |
| 2 | 黏弹性表面活性剂压裂液的研究与应用进展显示文摘黏弹性表面活性剂压裂液是以黏弹性表面活性剂为主剂的清洁压裂液。黏弹性表面活性剂压裂液体系具有破胶后无残渣、携砂性好、滤失控制性能好等特点,但随着对环保问题的日益重视及钻井深度的不断增加,丰富黏弹性表面活性剂压裂液体系迫在眉睫。本文介绍了黏弹性表面活性剂压裂液的发展和应用。根据压裂液配方不同,将其分为常规黏弹性表面活性剂压裂液和非常规新型黏弹性表面活性剂压裂液,总结了不同种类的黏弹性表面活性剂压裂液的组成、耐温耐剪切等性能及应用情况。分析表明,降低成本、研制简单的配制工艺是常规黏弹性表面活性剂压裂液的主要发展方向;在油田进行大规模实际应用及得到更完善的体系是非常规新型黏弹性表面活性剂压裂液的主要发展方向。 | 潘一 王瞳煜 杨双春 王世栋 ABDUL QAYUM Zain Ullah 刘子杰 | 2018 | 化工进展2018，37，4： | 11 |
| 3 | Multivariate metal-organic frameworks显示文摘Reticular chemistry is founded upon the principles of linking simple organic and inorganic building blocks through strong bonds to form extended,porous and crystalline solids,such as metal-organic frameworks(MOFs)[1].This field | Aasif Helal Zain H.Yamani Kyle E.Cordova Omar M.Yaghi | 2017 | National Science Review2017，4，3： | 10 |
| 4 | Biochemical mechanisms of the RNA-induced silencing complex显示文摘在不到 10 年里自从它的开始, RNA 干扰(RNAi ) 在生物医学的科学上有非凡的影响。RNAi 被表明了到影响众多生物并且疾病小径。RNAi 技术的开发和采纳是丰富的从基本 loss-of-function 工具,到药品的目标确认的染色体宽的屏蔽图书馆和治疗学的开发。然而, RNAiis 的分子的机制理解远非完全。这简短评论的目的是在阐明加亮关键成就导致 RNA 的 silencing 建筑群并且到的生化学机制为这块地构画出主要挑战。 | Zain Paroo Qinghua Liu Xiaodong Wang | 2007 | Cell Research2007，17，3： | 5 |
| 5 | Nat Med:靶向两分子或有助于彻底治愈白血病显示文摘科学家在癌细胞内发现两个信号蛋白能够让癌细胞抵抗化疗。研究表明阻断这两种蛋白能够增强化疗对人类白血病小鼠模型的治疗效果。相关研究结果发表在国际学术期刊NatureMedicine上。研究人员发现在治疗中阻断c-Fos和Dusp1这两个蛋白能够治愈一些受激酶驱动且抵抗治疗的白血病和实体瘤。 | Meenu Kesarwani, Zachary Kincaid, Ahmed Gomaa, Erika Huber, Sara Rohrabaugh, Zain Siddiqui, Muhammad F Bouso, Kakajan Komurov, James C Mulloy, Jose A Cancelas, H Leighton Grimes Mohammad Azam Tahir Latif Ming Xu H Leighton Grimes Mohammad Azam | 2017 | 现代生物医学进展2017，17，17： | 4 |
| 6 | Non-alcoholic fatty liver and chronic kidney disease:Retrospect,introspect,and prospect显示文摘With the growing prevalence of obesity and diabetes in the United States and across the world,a rise in the overall incidence and prevalence of non-alcoholic fatty liver disease(NAFLD)is expected.The risk factors for NAFLD are also associated with the development of chronic kidney disease(CKD).We review the epidemiology,risk factors,genetics,implications of gut dysbiosis,and specific pathogenic mechanisms linking NAFLD to CKD.Mechanisms such as ectopic lipid accumulation,cellular signaling abnormalities,and the interplay between fructose consumption and uric acid accumulation have led to the emergence of potential therapeutic implications for this patient population.Transplant evaluation in the setting of both NAFLD and CKD is also reviewed.Potential strategies for surveillance and management include the monitoring of comorbidities,the use of non-invasive fibrosis scoring systems,and the measurement of laboratory markers.Lastly,we discuss the management of patients with NAFLD and CKD,from preventative measures to experimental interventions. | Rajiv Heda Masahiko Yazawa Michelle Shi Madhu Bhaskaran Fuad Zain Aloor Paul J Thuluvath Sanjaya K Satapathy | 2021 | World Journal of Gastroenterology2021，27，17： | 3 |
| 7 | Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial显示文摘 | Paul Moayyedi Michael G. Surette Peter T. Kim Josie Libertucci Melanie Wolfe Catherine Onischi David Armstrong John K. Marshall Zain Kassam Walter Reinisch Christine H. Lee | 2015 | Gastroenterology2015，，： | 3 |
| 8 | Angiogenic peptide hydrogels for treatment of traumatic brain injury显示文摘Traumatic brain injury(TBI)impacts over 3.17 million Americans.Management of hemorrhage and coagulation caused by vascular disruption after TBI is critical for the recovery of patients.Cerebrovascular pathologies play an important role in the underlying mechanisms of TBI.The objective of this study is to evaluate a novel regenerative medicine for the injured tissue after brain injury.We utilized a recently described synthetic growth factor with angiogenic potential to facilitate vascular growth in situ at the injury site.Previous work has shown how this injectable self-assembling peptide-based hydrogel(SAPH)creates a regenerative microenvironment for neovascularization at the injury site.Supramolecular assembly allows for thixotropy;the injectable drug delivery system provides sustained in vivo efficacy.In this study,a moderate blunt injury model was used to cause physical vascular damage and hemorrhage.The angiogenic SAPH was then applied directly on the injured rat brain.At day 7 post-TBI,significantly more blood vessels were observed than the sham and injury control group,as well as activation of VEGF-receptor 2,demonstrating the robust angiogenic response elicited by the angiogenic SAPH.Vascular markers von-Willebrand factor(vWF)andα-smooth muscle actin(α-SMA)showed a concomitant increase with blood vessel density in response to the angiogenic SAPH.Moreover,blood brain barrier integrity and blood coagulation were also examined as the parameters to indicate wound recovery post TBI.Neuronal rescue examination by NeuN and myelin basic protein staining showed that the angiogenic SAPH may provide and neuroprotective benefit in the long-term recovery. | Xiaotang Ma Agnieszka Agas Zain Siddiqui KaKyung Kim Patricia Iglesias-Montoro Jagathi Kalluru Vivek Kumar James Haorah | 2020 | Bioactive Materials2020，5，1： | 3 |
| 9 | Vertical axis wind turbine – A review of various configurations and design techniques显示文摘 | Muhammad Mahmood Aslam Bhutta Nasir Hayat Ahmed Uzair Farooq Zain Ali Sh. Rehan Jamil Zahid Hussain | 2011 | Renewable and Sustainable Energy Reviews2011，，4： | 3 |
| 10 | Telemedicine,the current COVID-19 pandemic and the future:a narrative review and perspectives moving forward in the USA显示文摘A narrative review was conducted to examine the current state of the utilisation of telemedicine amid the current COVID-19 pandemic and to evaluate the benefits of continuing telemedicine usage in the future.A literature review was performed for articles related to telemedicine.Databases including PubMed,Google Scholar,Cochrane Library and Ovid MEDLINE were searched.Three reviewers independently performed article selection based on relevance to our topic.We included all articles between 1990 and 2020 related to telemedicine using the following keywords:‘telemedicine’,‘telehealth’,‘policy’,‘COVID-19’,‘regulation’,‘rural’,‘physical examination’,‘future’.A total of 60 articles were identified,and through careful selection we narrowed the final number of articles to 42 based on relevance to our topic.Telemedicine has been rapidly evolving over the past several decades.Issues with regulation and reimbursement have prevented its full immersion into the healthcare system.During the current pandemic,Centers for Medicare and Medicaid services have expanded access to telemedicine services.The advantages of telemedicine moving forward include its cost-effectiveness,ability to extend access to specialty services and its potential to help mitigate the looming physician shortage.Disadvantages include lack of available technological resources in certain parts of the country,issues with security of patient data,and challenges in performing the traditional patient examination.It is critically important that changes are made to fully immerse telemedicine services into the healthcare landscape in order to be prepared for future pandemics as well as to reap the benefits of this service in the future. | Asim Kichloo Michael Albosta Kirk Dettloff Farah Wani Zain El-Amir Jagmeet Singh Michael Aljadah Raja Chandra Chakinala Ashok Kumar Kanugula Shantanu Solanki Savneek Chugh | 2020 | Family Medicine and Community Health2020，8，3： | 3 |
| 11 | Development of Soda Residue Concrete Expansion Agent显示文摘A new type of concrete expansion agent has been successfully developed for the first time in the world by utilizing an industrial waste residue soda residue and an industrial wasteliquor.Adding 3%-6% of the agent into Portland cement enables a shrinkage compensating concrete to be prepared.Mortar and concrete containing this expansion agent have better shrinkage compensating and mechanical properties.The raw materials component,production process,technical properties,micro analysis of mortar made with this expansion agent,mechanism of expansion and research results are described in this article.The experimental results show that the new type of concrete expansion agent accords with the standard and its main mineral component is xCaO ySO 3 zAl 2O 3. | 王宝民 M F Mohd Zain F C Lai | 2003 | Journal of Wuhan University of Technology(Materials Science)2003，18，3： | 3 |
| 12 | Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer显示文摘Epidermal growth factor receptor(EGFR) has been an attractive target for treatment of epithelial cancers, including colorectal cancer(CRC). Evidence from clinical trials indicates that cetuximab and panitumumab(antiEGFR monoclonal antibodies) have clinical activity in patients with metastatic CRC. The discovery of intrinsic EGFR blockade resistance in Kirsten RAS(KRAS)-mutant patients led to the restriction of anti-EGFR antibodies to KRAS wild-type patients by Food and Drug Administration and European Medicine Agency. Studies have since focused on the evaluation of biomarkers to identify appropriate patient populations that may benefit from EGFR blockade. Accumulating evidence suggests that patients with mutations in EGFR downstream signaling pathways including KRAS, BRAF, PIK3CA and PTEN could be intrinsically resistant to EGFR blockade. Recent whole genome studies also suggest that dynamic alterations in signaling pathways downstream of EGFR leads to distinct oncogenic signatures and subclones which might have some impact on emerging resistance in KRAS wild-type patients. While anti-EGFR monoclonal antibodies have a clear potential in the management of a subset of patients with metastatic CRC, further studies are warranted to uncover exact mechanisms related to acquired resistance to EGFR blockade. | Zain A Sobani Ashwin Sawant Mikram Jafri Amit Keith Correa Ibrahim Halil Sahin | 2016 | World Journal of Clinical Oncology2016，7，5： | 3 |
| 13 | Reconfigurable intelligent surface-aided wireless communications: An overview显示文摘The reconfigurable intelligent surface(RIS)is an emerging technology,which will hopefully bring a new revolution in wireless communications.The RIS technology can be deployed in an indoor/outdoor environment to dynamically manipulate the propagation environment.The RIS consists of a large number of independently controllable passive elements,and these elements are involved in realizing high passive beamforming gain.Different from the conventional active phased antenna array,there is no dedicated radio-frequency(RF)chain installed at the RIS to perform complex signal processing operations.Therefore,it does not incur additional noise while retransmitting the incident wave,which is substantially a unique feature from the conventional wireless communication systems.Taking advantage of its working principle,RIS has been deployed in various practical scenarios.In this tutorial,at first we will review the latest advances in RIS,including the application scenarios such as the system and channel model,the information theoretic analysis,the physical realization and design,key signal processing techniques such as precoding and channel estimation,and prototyping.Finally,we discuss interesting future research problems for the RIS-aided communications. | Muhammad Zain Siddiqi Talha Mir | 2022 | Intelligent and Converged Networks2022，3，1： | 3 |
| 14 | Infectious diseases in the aftermath of monsoon flooding in Pakistan显示文摘Pakistan is ranked 9th in terms of flood-affected countries worldwide.In the summer of 2010,the northern province of Khyber-Pakhtunkhwa received more than 312 mm of rain in a 56 hour period.This resulted in over 1 600 deaths across the region.In addition,over 14 million people were directly affected by this record-breaking deluge.Flood affected regions serve as ideal breeding grounds for pathogens,leading to the spread of diseases.The poor standards of hygiene in camps set up for individuals displaced by the floods also contribute to this.It is essential that those involved in relief efforts are aware of the epidemiology of diseases that have historically seen a sudden upsurge after natural disasters.Keeping this in mind,we conducted a simple review of literature.An extensive literature search was conducted using the PubMed data base and online search engines.Articles published in the last 20 years were considered along with some historical articles where a background was required.Seven major diseases were identified to increase substantially in the aftermath of natural disasters.They were then classified into acute and sub-acute settings.Diarrhea,skin&eye infections and leptospirosis were identified in the acute setting while malaria,leishmaniasis,respiratory infections and hepatitis were identified in the sub-acute setting. | Maryam Baqir Zain A Sobani Amyn Bhamani Nida Shahab Bham Sidra Abid Javeria Farook M Asim Beg | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，1： | 2 |
| 15 | A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease显示文摘 | Shamsul Zain Rosmawati Mohamed Sanjiv Mahadeva Phaik Cheah Sanjay Rampal Roma Basu Zahurin Mohamed | 2012 | Human Genetics2012，，7： | 2 |
| 16 | Cells and material-based strategies for regenerative endodontics显示文摘 The carious process leads to inflammation of pulp tissue.Current care options include root canal treatment or apexification.These procedures,however,result in the loss of tooth vitality,sensitivity,and healing.Pulp capping and dental pulp regeneration are continually evolving techniques to regenerate pulp tissue,avoiding necrosis and loss of vitality.Many studies have successfully employed stem/progenitor cell populations,revascularization approaches,scaffolds or material-based strategies for pulp regeneration.Here we outline advantages and disadvantages of different methods and techniques which are currently being used in the field of regenerative endodontics.We also summarize recent findings on efficacious peptide-based materials which target the dental niche.. | Zain Siddiqui Amanda M.Acevedo-Jake Alexandra Griffith Nurten Kadincesme Kinga Dabek Dana Hindi Ka Kyung Kim Yoshifumi Kobayashi Emi Shimizu Vivek Kumar | 2022 | Bioactive Materials2022，7，8： | 2 |
| 17 | iPSC-derived cranial neural crest-like cells can replicate dental pulp tissue with the aid of angiogenic hydrogel显示文摘The dental pulp has irreplaceable roles in maintaining healthy teeth and its regeneration is a primary aim of regenerative endodontics.This study aimed to replicate the characteristics of dental pulp tissue by using cranial neural crest(CNC)-like cells(CNCLCs);these cells were generated by modifying several steps of a previously established method for deriving NC-like cells from induced pluripotent stem cells(iPSCs).CNC is the anterior region of the neural crest in vertebrate embryos,which contains the primordium of dental pulp cells or odontoblasts.The produced CNCLCs showed approximately 2.5-12,000-fold upregulations of major CNC marker genes.Furthermore,the CNCLCs exhibited remarkable odontoblastic differentiation ability,especially when treated with a combination of the fibroblast growth factors(FGFs)FGF4 and FGF9.The FGFs induced odontoblast marker genes by 1.7-5.0-fold,as compared to bone morphogenetic protein 4(BMP4)treatment.In a mouse subcutaneous implant model,the CNCLCs briefly fated with FGF4+FGF9 replicated dental pulp tissue characteristics,such as harboring odontoblast-like cells,a dentin-like layer,and vast neovascularization,induced by the angiogenic self-assembling peptide hydrogel(SAPH),SLan.SLan acts as a versatile biocompatible scaffold in the canal space.This study demonstrated a successful collaboration between regenerative medicine and SAPH technology. | Yoshifumi Kobayashi Julie Nouet Erdenechimeg Baljinnyam Zain Siddiqui Daniel HFine Diego Fraidenraich Vivek A.Kumar Emi Shimizu | 2022 | Bioactive Materials2022，7，8： | 2 |
| 18 | Week Ahead Electricity Power and Price Forecasting Using Improved DenseNet-121 Method显示文摘In the Smart Grid(SG)residential environment,consumers change their power consumption routine according to the price and incentives announced by the utility,which causes the prices to deviate from the initial pattern.Thereby,electricity demand and price forecasting play a significant role and can help in terms of reliability and sustainability.Due to the massive amount of data,big data analytics for forecasting becomes a hot topic in the SG domain.In this paper,the changing and non-linearity of consumer consumption pattern complex data is taken as input.To minimize the computational cost and complexity of the data,the average of the feature engineering approaches includes:Recursive Feature Eliminator(RFE),Extreme Gradient Boosting(XGboost),Random Forest(RF),and are upgraded to extract the most relevant and significant features.To this end,we have proposed the DensetNet-121 network and Support Vector Machine(SVM)ensemble with Aquila Optimizer(AO)to ensure adaptability and handle the complexity of data in the classification.Further,the AO method helps to tune the parameters of DensNet(121 layers)and SVM,which achieves less training loss,computational time,minimized overfitting problems and more training/test accuracy.Performance evaluation metrics and statistical analysis validate the proposed model results are better than the benchmark schemes.Our proposed method has achieved a minimal value of the Mean Average Percentage Error(MAPE)rate i.e.,8%by DenseNet-AO and 6%by SVM-AO and the maximum accurateness rate of 92%and 95%,respectively. | Muhammad Irfan Ali Raza Faisal Althobiani Nasir Ayub Muhammad Idrees Zain Ali Kashif Rizwan Abdullah Saeed Alwadie Saleh Mohammed Ghonaim Hesham Abdushkour Saifur Rahman Omar Alshorman Samar Alqhtani | 2022 | Computers, Materials & Continua2022，，9： | 2 |
| 19 | Exploring the Trade-off Between Accuracy and Observational Latency in Action Recognition显示文摘 | Chris Ellis Syed Zain Masood Marshall F. Tappen Joseph J. LaViola Rahul Sukthankar | 2013 | International Journal of Computer Vision2013，，3： | 1 |
| 20 | Biodistribution of phosphodiester and phosphorothioate siRNA 显示文摘 | BRAASCH DA ZAIN P ANCA C | 2004 | Bioorg Med Chem Lett2004，14，12： | 1 |
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