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| 1 | Heat Treatment Effect on Microstructure, Hardness and Wear Resistance of Cr26 White Cast Iron显示文摘High chromium cast iron(HCCI) is taken as material of coal water slurry pump impeller, but it is susceptible to produce serious abrasive wear and erosion wear because of souring of hard coal particles. The research on optimization of heat treatments to improve abrasive wear properties of HCCI is insufficient, so effect of heat treatments on the microstructure, hardness, toughness, and wear resistance of Cr26 HCCI is investigated to determine the optimal heat treatment process for HCCI. A series of heat treatments are employed. The microstructures of HCCI specimens are examined by using optical microscopy and scanning electron microscopy. The hardness and impact fracture toughness of as-cast and heat treated specimens are measured. The wear tests are assessed by a Type M200 ring-on block wear tester. The results show the following: With increase of the quenching temperature from 950 ℃ to 1050 ℃, the hardness of Cr26 HCCI increased to a certain value, kept for a time and then decreased. The optimal heat treatment process is 2 h quenching treatment at 1000 ℃, followed by a subsequent 2 h tempering at 400 ℃. The hardness of HCCI is related to the precipitation and redissolution of secondary carbides in the process of heat treatment. The subsequent tempering treatment would result in a slight decrease of hardness but increase of toughness. The wear resistance is much related to the 'supporting' effect of the matrix and the 'protective' effect of the hard carbide embedded in the matrix, and the wear resistance is further dependent on the hardness and the toughness of the matrix. This research can provide an important insight on developing an optimized heat treatment method to improve the wear resistance of HCCI. | ZHOU Shaoping SHEN Yehui ZHANG Hao CHEN Dequan | 2015 | Chinese Journal of Mechanical Engineering2015，28，1： | 7 |
| 2 | Genome-and transcriptome-wide association studies provide insights into the genetic basis of natural variation of seed oil content in Brassica napus显示文摘Seed oil content(SOC)is a highly important and complex trait in oil crops.Here,we decipher the genetic basis of natural variation in SOC of Brassica napus by genome-and transcriptome-wide association studies using 505 inbred lines.We mapped reliable quantitative trait loci(QTLs)that control SOC in eight environments,evaluated the effect of each QTL on SOC,and analyzed selection in QTL regions during breeding.Six-hundred and ninety-two genes and four gene modules significantly associated with SOC were identified by analyzing population transcriptomes from seeds.A gene prioritization framework,POCKET(prioritizing the candidate genes by incorporating information on knowledge-based gene sets,effects of variants,genome-wide association studies,and transcriptome-wide association studies),was implemented to determine the causal genes in the QTL regions based on multi-omic datasets.A pair of homologous genes,BnPMT6s,in two QTLs were identified and experimentally demonstrated to negatively regulate SOC.This study provides rich genetic resources for improving SOC and valuable insights toward understanding the complex machinery that directs oil accumulation in the seeds of B.napus and other oil crops. | Shan Tang Hu Zhao Shaoping Lu Liangqian Yu Guofang Zhang Yuting Zhang Qing-Yong Yang Yongming Zhou Xuemin Wang Wei Ma Weibo Xie Liang Guo | 2021 | Molecular Plant2021，14，3： | 6 |
| 3 | Occurrence of human pathogenic bacteria carrying antibiotic resistance genes revealed by metagenomic approach: A case study from an aquatic environment显示文摘Antibiotic resistance genes(ARGs), human pathogenic bacteria(HPB), and HPB carrying ARGs are public issues that pose a high risk to aquatic environments and public health. Their diversity and abundance in water, intestine, and sediments of shrimp culture pond were investigated using metagenomic approach. A total of 19 classes of ARGs, 52 HPB species, and 7 species of HPB carrying ARGs were found. Additionally, 157, 104, and 86 subtypes of ARGs were detected in shrimp intestine, pond water, and sediment samples, respectively. In all the samples, multidrug resistance genes were the highest abundant class of ARGs. The dominant HPB was Enterococcus faecalis in shrimp intestine, Vibrio parahaemolyticus in sediments, and Mycobacterium yongonense in water, respectively. Moreover, E. faecalis(contig Intestine_364647)and Enterococcus faecium(contig Intestine_80272) carrying efr A, efr B and ANT(6)-Ia were found in shrimp intestine, Desulfosaricina cetonica(contig Sediment_825143) and Escherichia coli(contig Sediment_188430) carrying mex B and APH(3′)-IIa were found in sediments, and Laribacter hongkongensis(contig Water_478168 and Water_369477), Shigella sonnei(contig Water_880246),and Acinetobacter baumannii(contig Water_525520) carrying sul1, sul2, ere A, qac H, OXA-21, and mph D were found in pond water. Mobile genetic elements(MGEs) analysis indicated that horizontal gene transfer(HGT) of integrons, insertion sequences, and plasmids existed in shrimp intestine, sediment, and water samples, and the abundance of integrons was higher than that of other two MGEs. The results suggested that HPB carrying ARGs potentially existed in aquatic environments, and that these contributed to the environment and public health risk evaluation. | Renjun Zhou Shenzheng Zeng Dongwei Hou Jian Liu Shaoping Weng Jianguo He Zhijian Huang | 2019 | Journal of Environmental Sciences2019，31，6： | 5 |
| 4 | Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia显示文摘好攻击的 NK 房间白血病(ANKL ) 是在从亚洲的人之中是更流行的 NK 房间瘤的一种稀罕形式并且中央并且南美洲。病人们通常在天以内死到月,甚至在收到迅速的治疗学的管理以后。这里,我们由集成整个染色体执行了 ANKL 的第一全面研究, transcriptome 并且定序指向,象功能的试金一样的 cytokine 数组。在 JAK-STAT 小径的变化在 48% 被识别(14/29 ) ANKL 病人,当细胞外的 STAT3 激发器 IL10 被 56 褶层的一般水准提高时(P < 0.0001 ) 在检查的所有病人的血浆。另外的经常变异的基因包括的 TP53 (34%) , TET2 (28%) , CREBBP (21%) 和 MLL2 (21%) 。耐心的 NK 白血病房间在多重新陈代谢的小径显示出 STAT3 phosphorylation, MYC 表示和 transcriptional 活动的突出的激活。机能上地, STAT3 激活和 MYC 表示为 ANKL 房间的增长和幸存是批评的。发信号的 STAT 调整了发信号的 MYC 抄写节目,和两 STAT, MYC 抄写被要求维持核苷酸合成和 glycolysis 的激活。一起, JAK-STAT 小径在 ANKL 为 genomic 改变和 IL10 刺激代表一个主要目标。这最新发现的 JAK/STAT-MYC-biosynthesis 轴可以在对待白血病的这种子类型为新奇治疗学的策略的发展提供机会。 | Liang Huang Dan Liu Na Wang Shaoping Ling Yuting Tang Jun Wu Lingtong Hao Hui Luo Xuelian Hu Lingshuang Sheng Lijun Zhu Di Wang Yi Luo Zhen Shang Min Xiao Xia Mao Kuangguo Zhou Lihua Cao Lili Dong Xinchang Zheng Pinpin Sui Jianlin He Shanlan Mo Jin Yan Qilin Ao Lugui Qiu Hongsheng Zhou Qifa Liu Hongyu Zhang Jianyong Li Jie Jin Li Fu Weili Zhao Jieping Chen Xin Du Guoliang Qing Hudan Liu Xin Liu Gang Huang Ding Ma Jianfeng Zhou Qian-fei Wang | 2018 | Cell Research2018，28，2： | 5 |
| 5 | Crack Detection in Pipes with Different Bend Angles Based on Ultrasonic Guided Wave显示文摘Pipeline plays an indispensable role in process industries,because the progressing crack-like defects of in it may result in serious accidents and significant economic losses.Therefore,it is essential to detect the cracks occurred in pipelines.The axial crack-like defects in elbows with different angle are inspected by using the T(0,1)mode guided waves,in which different configurations including 45°,90°,135°and 180°(straight pipe)are considered respectively.Firstly,the detection sensitivity for different defect location is experimentally investigated.After that,finite element simulation is used to explore the propagation behaviors of T(0,1)mode in different bend structures.Simulation and experiment results show that the crack in different areas of the elbow can affect the detection sensitivity.It can be found that the detection sensitivity of crack in the middle area of the elbow is higher compared to the extrados and intrados of the elbow.Finally,the mode conversion is also investigated when the T(0,1)crosses the bend,and the results show that bend is a key factor to the mode conversion phenomenon which presents between the T(0,1)mode and F(1,2)mode. | Qi Minxin Chen Shaojie Zhou Shaoping Li Yong Jia Jiuhong | 2017 | Transactions of Nanjing University of Aeronautics and Astronautics2017，34，3： | 3 |
| 6 | Geo-tectonic conditions of the formation of Proterozoic large and superlarge ore deposits along northwestern margin of North China Plate显示文摘 | Guizhong Xu Qiantao Bian Shaoping Zhou | 1998 | Science in China Series D: Earth Sciences1998，，1： | 1 |
| 7 | Wind- induced vibration responses of prestressed double-layered spherical latticed shells显示文摘 | ZHOU ZHEN LI ZHIMING MENG SHAOPING | 2011 | International Journal of Steel Structures2011，11，2： | 1 |
| 8 | A fractal model forgravity sedimentation of ultra-fine particles suspension显示文摘 | Zhou Shaoping Yuan Quan GeXiaoling | 2012 | AdvancedMaterials Research2012，，： | 1 |
| 9 | Analysis of electromagnetic pulses generation from laser coupling with polymer targets: Effect of metal content in target显示文摘Powerful lasers interacting with solid targets can generate intense electromagnetic pulses(EMPs).In this study,EMPs produced by a pulsed laser(1 ps,100 J)shooting at CH targets doped with different titanium(Ti)contents at the XG-III laser facility are measured and analyzed.The results demonstrate that the intensity of EMPs first increases with Ti doping content from 1%to 7%and then decreases.The electron spectra show that EMP emission is closely related to the hot electrons ejected from the target surface,which is confirmed by an analysis based on the target–holder–ground equivalent antenna model.The conclusions of this study provide a new approach to achieve tunable EMP radiation by adjusting the metal content of solid targets,and will also help in understanding the mechanism ofEMPgeneration and ejection of hot electrons during laser coupling with targets. | Yadong Xia Feng Zhang Hongbo Cai Weimin Zhou Chao Tian Bo Zhang Dongxiao Liu Tao Yi Yilin Xu Feng Wang Tingshuai Li Shaoping Zhu | 2020 | Matter and Radiation at Extremes2020，5，1： | 1 |
| 10 | Solutions to semilinear elliptic problems with combined nonlinearities 显示文摘 | Li Shujie Wu Shaoping Zhou Huansong | 2002 | J Differential Equations2002，，185： | 1 |
| 11 | Stability analysis of prestressed space truss structures based on the imperfect truss element显示文摘 | Zhou Zhen Meng Shaoping Wu Jing | 2009 | International Journal of Steel Structures2009，9，3： | 1 |
| 12 | Proteome-wide identification of S-sulfenylated cysteines response to salt stress in Brassica napus root显示文摘Reactive oxygen species(ROS)play a key role in a variety of biological processes,such as the perception of abiotic stress,the integration of different environmental signals,and the activation of stress response networks.Salt stress could induce an increased ROS accumulation in plants,disrupting intracellular redox homeostasis,leading to posttranslational modifications(PTMs)of specific proteins,and eventually causing adaptive changes in metabolism.Here,we performed an iodoTMT-based proteomic approach to identify the sulfenylated proteins in B.napus root responsing to salt stress.Totally,1348 sulfenylated sites in 751 proteins were identified and these proteins were widely existed in different cell compartments and processes.Our study revealed that proteins with changed abundance and sulfenylation level in B.napus root under salt stress were mainly enriched in the biological processes of ion binding,glycolysis,ATP binding,and oxidative stress response.This study displays a landscape of sulfenylated proteins response to salt stress in B.napus root and provides some theoretical support for further understanding of the molecular mechanisms of redox regulation under salt stress in plants. | Qian Qu Xiaowei Wu Qing Zhou Shaoping Lu Xuan Yao Liang Guo Liangqian Yu | 2023 | Oil Crop Science2023，8，4： | 0 |
| 13 | The mathematical model and simulation of the electrostatic suspension system in the vertical direction显示文摘In order to research the vibration law of electrostatic suspension systems in the vertical direction, the mathematical model as a nonlinear differential equation is established. A series of simulation is carried out. The results show that the solution of the differential equation is a periodic function. The amplitude becomes bigger with the original velocity increased. The period becomes smaller with the original velocity increasing. The numerical methods are presented to derive the amplitude and the frequency, and the results coincide with that of the simulation. The condition during which the simple harmonic vibration arises is pointed out. The expressions for the amplitude and the period of simple harmonic vibration are derived respectively, and the results are the same with that of the simulation. This study is helpful for researching the vibration characteristics of the electrostatic suspension system. The external disturb should be controlled to lower the amplitude and the frequency of the vibration. | Ku Shaoping Zhou Zude Hu Yefa | 2008 | Engineering Sciences2008，6，2： | 0 |
| 14 | Hypothermic intervention for 3 hours inhibits apoptosis in neonatal rats with hypoxic-ischemic brain damage显示文摘A neonatal rat model of hypoxic-ischemic brain damage was designed and implemented in this study. Rats were subjected to hypothermia at 31°C immediately following hypoxia-ischemia for either 3, 6 or 15 hours. TdT-mediated dUTP nick end labeling demonstrated that the number of apoptotic cells was reduced in the rat cerebral cortex, hippocampus and periventricular white matter following hypothermia. Immunohistochemistry revealed that Bcl-2 and p16 expression were decreased. Inhibition of apoptosis was greatest with the 3 hour hypothermic treatment, followed by hypothermia for 6 hours. In contrast, hypothermia for 15 hours led to a decrease in neuronal number in the cerebral cortex. The results demonstrate that hypothermic intervention at 31°C protects brain tissue against hypoxic-ischemic brain damage by inhibiting apoptosis, and that the optimal length of treatment is 3 hours. | Yale Guo Zhankui Li Ruilin Li Baoshan Su Shaoping Huang Jianping Zhou | 2011 | Neural Regeneration Research2011，6，22： | 0 |
| 15 | Identification of methylated differentially expressed hub genes in systemic lupus erythematosus patients by WGCNA-based epigenome-wide and transcriptome-wide analysis显示文摘Systemic lupus erythematosus(SLE)is an autoimmune disease,characterized by the production of autoantibodies and the involvement of multi-systems.In order to explore its molecular mechanism,we,using bioinformatics analysis and wet lab experiments,identified two key genes in SLE patients. | Qiao Zhou Li Long Xixi Chen Xiaobo Huang Shaoping Deng Yi Wang | 2023 | Genes & Diseases2023，10，5： | 0 |
| 16 | Commissioning experiment of the high-contrast SILEX-Ⅱ multi-petawatt laser facility显示文摘The results of a commissioning experiment on the SILEX-Ⅱlaser facility(formerly known as CAEP-PW)are reported.SILEX-Ⅱis a complete optical parametric chirped-pulse amplification laser facility.The peak power reached about 1 PWin a 30 fs pulse duration during the experiment.The laser contrast was better than 1010 at 20 ps ahead of the main pulse.In the basic laser foil target interaction,a set of experimental data were collected,including spatially resolved x-ray emission,the image of the coherent transition radiation,the harmonic spectra in the direction of reflection,the energy spectra and beam profile of accelerated protons,hot-electron spectra,and transmitted laser energy fraction and spatial distribution.The experimental results show that the laser intensity reached 531020 W/cm^(2) within a 5.8μm focus(FWHM).Significant laser transmission did not occur when the thickness of theCHfoil was equal to or greater than 50 nm.The maximum energy of the accelerated protons in the target normal direction was roughly unchanged when the target thickness varied between 50 nm and 15μm.The maximum proton energy via the target normal sheath field acceleration mechanism was about 21 MeV.We expect the on-target laser intensity to reach 10^(22) W/cm^(2) in the near future,after optimization of the laser focus and upgrade of the laser power to 3 PW. | Wei Hong Shukai He Jian Teng Zhigang Deng Zhimeng Zhang Feng Lu Bo Zhang Bin Zhu Zenghai Dai Bo Cui Yuchi Wu Dongxiao Liu Wei Qi Jinlong Jiao Faqiang Zhang Zuhua Yang Feng Zhang Bi Bi Xiaoming Zeng Kainan Zhou Yanlei Zuo Xiaojun Huang Na Xie Yi Guo Jingqin Su Dan Han Ying Mao Leifeng Cao Weimin Zhou Yuqiu Gu Feng Jing Baohan Zhang Hongbo Cai Minqing He Wudi Zheng Shaoping Zhu Wenjun Ma Dahui Wang Yinren Shou Xueqing Yan Bin Qiao Yi Zhang Congling Zhong Xiaohui Yuan and Wenqing Wei | 2021 | Matter and Radiation at Extremes2021，6，6： | 0 |
| 17 | Bacterial and eukaryotic community interactions might contribute to shrimp culture pond soil ecosystem at different culture stages显示文摘Sedimentary bacterial and eukaryotic communities are major components of the aquatic ecosystem.Revealing the linkages between their community structure and interactions is crucial to understand the diversity and functions of aquatic and soil ecosystems.However,how their diversity and assembly contribute to their interactions on time scale is unclear.This study examined sedimentary bacterial and eukaryotic communities in shrimp culture ponds at different culture stages.The most abundant bacteria were Proteobacteria(38.27%),whereas the most abundant eukaryotes were Chytridiomycota(27.48%).Bacterial and eukaryotic diversities were correlated(P<0.05),implying the strong interactions between bacteria and eukaryotes.Results showed that the bacterial and eukaryotic communities became increasingly similar on a local scale along with the shrimp culture.Only the eukaryotic community significantly increased in similarity along with the shrimp culture(P<0.05),suggesting that the sedimentary eukaryotic community structure is sensitive under shrimp culture.Co-occurrence network modeling indicated that positive microbial interactions were dominant.The homogeneous selection was the major driver of community assembly.Bacterial diversity negatively correlated with operational taxonomic units and positive links in networks(P<0.05),whereas eukaryotic diversities positively correlated with positive links in networks(P<0.05).This study broadens our knowledge about sedimentary microbial diversity,community assembly,and interaction patterns on time scale,providing a reference for the sustainable management in aquaculture production. | Renjun Zhou Hao Wang Dongdong Wei Shenzheng Zeng Dongwei Hou Shaoping Weng Jianguo He Zhijian Huang | 2022 | Soil Ecology Letters2022，4，2： | 0 |
| 18 | Correlation Function of Clumps for Electrons in Localized Coherent Langmuir Fields显示文摘A correlation function of electrons interacting with localized coherent Langmuir wave packets is obtained by particle simulation.It is shown that the peak behavior of the correlation function for sufficiently small relative coordinates r^(0) and u^(0) in phase space also occurs in a spatially inhomogeneous system,and the neighboring particles in phase space are correlated with each other for a lifetime exceeding the coherent time.Our numerical results display the clump effects,which are consistent with previous theoretical prediction of the relative diffusion behavior. | ZHOU Cangtao HE Xiantu ZHU Shaoping | 1992 | Chinese Physics Letters1992，9，8： | 0 |
| 19 | Clinical features of 162 fatal cases of COVID-19:a multi-center retrospective study显示文摘Background:The coronavirus disease 2019(COVID-19)has affected approximately 2 million individuals worldwide;however,data regarding fatal cases have been limited.Objective:To report the clinical features of 162 fatal cases of COVID-19 from 5 hospitals in Wuhan between December 30,2019 and March 12,2020.Methods:The demographic data,signs and symptoms,clinical course,comorbidities,laboratory findings,computed tomographic(CT)scans,treatments,and complications of the patients with fatal cases were retrieved from electronic medical records.Results:The median patient age was 69.5(interquartile range:63.0–77.25)years,and 80%of the patients were over 61 years.A total of 112(69.1%)patients were men.Hypertension(45.1%)was the most common comorbidity,while 59(36.4%)patients had no comorbidity.At admission,131(81.9%)patients had severe or critical COVID-19,whereas 39(18.1%)patients with hypertension or chronic lung disease had moderate COVID-19.In total,126(77.8%)patients received antiviral treatment,while 132(81.5%)patients received glucocorticoid treatment.A total of 116(71.6%)patients were admitted to the intensive care unit(ICU),and 137(85.1%)patients received mechanical ventilation.Most patients received mechanical ventilation before ICU admission.Approximately 93.2%of the patients developed respiratory failure or acute respiratory distress syndrome.There were no significant differences in the inhospital survival time among the hospitals(P=0.14).Conclusion:Young patients with moderate COVID-19 without comorbidity at admission could also develop fatal outcomes.The in-hospital survival time of the fatal cases was similar among the hospitals of different levels in Wuhan. | Xianlong Zhou Guoyong Ding Qing Fang Jun Guo Luyu Yang Ping Wang Shou-Zhi Fu Ang Li Jian Xia Jiangtao Yu Jianyou Xia Min Ma Zhuanzhuan Hu Lei Huang Ruining Liu Cheng Jiang Shaoping Li Mingxia Yu Xizhu Xu Yan Zhao Quan Hu Weijia Xing Zhigang Zhao | 2022 | Emergency and Critical Care Medicine2022，2，3： | 0 |
| 20 | Ganoderma atrum polysaccharide relieves mitochondrial dysfunction to alleviate hydrogen peroxide-induced senescence via activating autophagy显示文摘Polysaccharides from genus Ganoderma have prominent anti-aging effect,but their mechanisms are incompletely clarified.In our previous experiments,Ganoderma atrum polysaccharide(PSG)was exhibited to significantly alleviate senescence and DNA damage of A375 cells.To investigate its underlying mechanism,we conducted RNA-Seq analysis and found that PSG upregulated autophagy and mitochondria pathways compared to the model group.Further experiments showed that PSG relieved mitochondrial dysfunction via inhibiting the accumulation of reactive oxygen species(ROS)and loss of the mitochondrial membrane potential(MMP).Meanwhile,PSG activated autophagy and enhanced lysosomal function through transcription factor EB(TFEB).Interestingly,the pretreatment of autophagy inhibitors bafilomycin A1(Baf A1)reversed the ROS decline induced by PSG,which subsequently increased cellular senescence of A375.In addition,PSG had a similar anti-aging effect on normal fibroblast WI-38.Taken together,PSG might reduce ROS levels through activating autophagy,which in turn suppressed mitochondrial dysfunction and cellular senescence. | Mi Guo Ke Zhang Duoduo Zhang Yujia Zhou Linyuan Liu Yu Wu Xingtao Zhou Shaoping Nie | 2022 | Journal of Future Foods2022，2，3： | 0 |
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