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1Flow field and pressure loss analysis of junction and its structure optimization of aircraft hydraulic pipe system显示文摘The flow field in junction is complicated due to the ripple property of oil flow velocity and different frequencies of two pumps in aircraft. In this study, the flow fields of T-junction and Y-junction were analyzed using shear stress transport (SST) model in ANSYS/CFX software. The simulation results identified the variation rule of velocity peak in T-junction with different frequencies and phase-differences, meanwhile, the eddy and velocity shock existed in the corner of the T-junction, and the limit working state was obtained. Although the eddy disappeared in Y-junction, the velocity shock and pressure loss were still too big. To address these faults, an arc-junction was designed. Based on the flow fields of arc-junction, the eddy in the junction corner disappeared and the maximum of velocity peak declined compared to T-and Y-junction. Additionally, 8 series of arc-junction with different radiuses were tested to get the variation rule of velocity peak. Through the computation of the pressure loss of three junctions, the arc-junction had a lowest loss value, and its pressure loss reached the minimum value when the curvature radius is 35.42 mm, meanwhile, the velocity shock has decreased in a low phase.Li Xin Wang Shaoping 2013Chinese Journal of Aeronautics2013,26,4:17
2Fault diagnosis of an intelligent hydraulic pump based on a nonlinear unknown input observer显示文摘Hydraulic piston pumps are commonly used in aircraft. In order to improve the viability of aircraft and energy efficiency, intelligent variable pressure pump systems have been used in aircraft hydraulic systems more and more widely. Efficient fault diagnosis plays an important role in improving the reliability and performance of hydraulic systems. In this paper, a fault diagnosis method of an intelligent hydraulic pump system(IHPS) based on a nonlinear unknown input observer(NUIO) is proposed. Different from factors of a full-order Luenberger-type unknown input observer, nonlinear factors of the IHPS are considered in the NUIO. Firstly, a new type of intelligent pump is presented, the mathematical model of which is established to describe the IHPS. Taking into account the real-time requirements of the IHPS and the special structure of the pump, the mechanism of the intelligent pump and failure modes are analyzed and two typical failure modes are obtained. Furthermore, a NUIO of the IHPS is performed based on the output pressure and swashplate angle signals. With the residual error signals produced by the NUIO, online intelligent pump failure occurring in real-time can be detected. Lastly, through analysis and simulation, it is confirmed that this diagnostic method could accurately diagnose and isolate those typical failure modes of the nonlinear IHPS. The method proposed in this paper is of great significance in improving the reliability of the IHPS.Zhonghai MA Shaoping WANG Jian SHI Tongyang LI Xingjian WANG 2018Chinese Journal of Aeronautics2018,31,2:13
3Hypoglycemic mechanism of polysaccharide from Cyclocarya paliurus leaves in type 2 diabetic rats by gut microbiota and host metabolism alteration显示文摘Diabetes mellitus is a serious threat to human health.Cyclocarya paliurus(Batal.)Iljinskaja(C.paliurus)is one of the traditional herbal medicine and food in China for treating type 2 diabetes,and the C.paliurus polysaccharides(CP)were found to be one of its major functional constituents.This research aimed at investigating the hypoglycemic mechanism for CP.It was found that CP markedly attenuated the symptoms of diabetes,and inhibited the protein expression of Bax,improved the expression of Bcl-2 in pancreas of diabetic rats,normalized hormones secretion and controlled the inflammation which contributed to the regeneration of pancreaticβ-cell and insulin resistance.CP treatment increased the beneficial bacteria genus Ruminococcaceae UCG-005 which was reported to be a key genus for protecting against diabetes,and the fecal short-chain fatty acids levels were elevated.Uric metabolites analysis showed that CP treatment helped to protect with the diabetes by seven significantly improved pathways closely with the nutrition metabolism(amino acids and purine)and energy metabolism(TCA cycle),which could help to build up the intestinal epithelial cell defense for the inflammation associated with the diabetes.Our study highlights the specific mechanism of prebiotics to attenuate diabetes through multi-path of gut microbiota and host metabolism.Qiqiong Li Jielun Hu Qixing Nie Xiao Chang Qingying Fang Junhua Xie Haishan Li Shaoping Nie 2021Science China(Life Sciences)2021,64,1:11
4An adaptive-order particle filter for remaining useful life prediction of aviation piston pumps显示文摘An accurate estimation of the remaining useful life(RUL) not only contributes to an effective application of an aviation piston pump, but also meets the necessity of condition based maintenance(CBM). For the current RUL evaluation methods, a model-based method is inappropriate for the degradation process of an aviation piston pump due to difficulties of modeling, while a data-based method rarely presents high-accuracy prediction in a long period of time. In this work,an adaptive-order particle filter(AOPF) prognostic process is proposed aiming at improving long-term prediction accuracy of RUL by combining both kinds of methods. A dynamic model is initialized by a data-driven or empirical method. When a new observation comes, the prior state distribution is approximated by a current model. The order of the current model is updated adaptively by fusing the information of the observation. Monte Carlo simulation is employed for estimating the posterior probability density function of future states of the pump's degradation.With updating the order number adaptively, the method presents a higher precision in contrast with those of traditional methods. In a case study, the proposed AOPF method is adopted to forecast the degradation status of an aviation piston pump with experimental return oil flow data, and the analytical results show the effectiveness of the proposed AOPF method.Tongyang LI Shaoping WANG Jian SHI Zhonghai MA 2018Chinese Journal of Aeronautics2018,31,5:7
5Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia显示文摘好攻击的 NK 房间白血病(ANKL ) 是在从亚洲的人之中是更流行的 NK 房间瘤的一种稀罕形式并且中央并且南美洲。病人们通常在天以内死到月,甚至在收到迅速的治疗学的管理以后。这里,我们由集成整个染色体执行了 ANKL 的第一全面研究, transcriptome 并且定序指向,象功能的试金一样的 cytokine 数组。在 JAK-STAT 小径的变化在 48% 被识别(14/29 ) ANKL 病人,当细胞外的 STAT3 激发器 IL10 被 56 褶层的一般水准提高时(P < 0.0001 ) 在检查的所有病人的血浆。另外的经常变异的基因包括的 TP53 (34%) , TET2 (28%) , CREBBP (21%) 和 MLL2 (21%) 。耐心的 NK 白血病房间在多重新陈代谢的小径显示出 STAT3 phosphorylation, MYC 表示和 transcriptional 活动的突出的激活。机能上地, STAT3 激活和 MYC 表示为 ANKL 房间的增长和幸存是批评的。发信号的 STAT 调整了发信号的 MYC 抄写节目,和两 STAT, MYC 抄写被要求维持核苷酸合成和 glycolysis 的激活。一起, JAK-STAT 小径在 ANKL 为 genomic 改变和 IL10 刺激代表一个主要目标。这最新发现的 JAK/STAT-MYC-biosynthesis 轴可以在对待白血病的这种子类型为新奇治疗学的策略的发展提供机会。Liang Huang Dan Liu Na Wang Shaoping Ling Yuting Tang Jun Wu Lingtong Hao Hui Luo Xuelian Hu Lingshuang Sheng Lijun Zhu Di Wang Yi Luo Zhen Shang Min Xiao Xia Mao Kuangguo Zhou Lihua Cao Lili Dong Xinchang Zheng Pinpin Sui Jianlin He Shanlan Mo Jin Yan Qilin Ao Lugui Qiu Hongsheng Zhou Qifa Liu Hongyu Zhang Jianyong Li Jie Jin Li Fu Weili Zhao Jieping Chen Xin Du Guoliang Qing Hudan Liu Xin Liu Gang Huang Ding Ma Jianfeng Zhou Qian-fei Wang 2018Cell Research2018,28,2:5
6Effect of pH,temperature and heating time on the formation of furan in sugar–glycine model systems显示文摘Furan(C4H4O)has been classified as a possible animal and human carcinogen by many international agencies.The formation of furan in three sugar–glycine models using glucose,fructose,and sucrose was investigated using headspace gas chromatography mass spectrometry method(HSGC–MS)with various dual combinations of three important heat processing conditions,i.e.pH,temperature,and heating time.Results indicated that furan levels from sugar–glycine model systems during the thermal processing can be attributed to selective sugar types,pH,temperature,and heating time.In glucose–glycine and fructose–glycine system,the lowest furan level was detected in acid condition but in sucrose–glycine system furan formed significantly lower(P<0.05)in acidic conditions the lowest furan level was found in alkaline conditions.The furan levels were observed to increase with heating time in all three model systems.Furthermore,less furan was generated in non-reducing sugar system(sucrose)than in reducing sugar system(glucose and fructose).Therefore,they demonstrate the possibility of limiting the formation of furan in heat processed foods by both the careful selection of carbohydrates(i.e.non-reducing sugars and reducing sugars)ingredients and appropriate processing conditions.©2013 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved.Shaoping Nie Jungen Huang Jielun Hu Yanan Zhang Sunan Wang Chang Li Massimo Marcone Mingyong Xie 2013Food Science and Human Wellness2013,2,2:4
7Free radical scavenging activity of Eagle tea and their flavonoids显示文摘In this study,an online HPLC-DAD-MS coupled with 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid)diammonium salt(A BTS)assay was employed for evaluating free radical scavenging activity of Eagle tea and their active components.Twenty-three chromatographic peaks were detected,and nineteen components had free radical scavenging activity.Among them,eight compounds were identified as flavonoids(hyperin,isoquercitrin,quercitrin,quercetin,kaempferol),catechins,chlorogenic acid and epicatechin based on MS data and standard chromatographic characters.Qiong Meng Zhengming Qian Xiaoxiang Li Deqiang Li Weihua Huang Jing Zhao Shaoping Li 2012Acta Pharmaceutica Sinica B2012,2,3:4
8Optimization of microwave-assisted extraction of bioactive alkaloids from lotus plumule using response surface methodology显示文摘In this work,a fast and efficient microwave-assisted extraction(MAE) method was developed to extract main bioactive alkaloids from lotus plumue.To optimize MAE conditions,three main factors were selected using univariate approach experiments,and then central composite design(CCD).The optimal extraction conditions were as follows:methanol concentration of 65%,microwave power of 200 W,and extraction time of 260 s.A high performance liquid chromatography–diode array detector(HPLC–DAD) method was established to quantitatively analyze these phytochemicals in different lotus plumule samples and in different part of lotus.Chromatographic separation was carried out on an Agilent Zorbax Extend-C_(18) column(4.6 mm×150 mm,3.5 μm).Gradient elution was applied with the mobile phase constituted with 0.1% triethylamine in water(A)and acetonitrile(B):40%-70% B at 0-8 min,70%-100% B at 8–9 min,100% B for 2 min,and then equilibrated with 40% B for 2 min.Wei Xiong Xianqiang Chen Guangping Lv Dejun Hu Jing Zhao Shaoping Li 2016Journal of Pharmaceutical Analysis2016,6,6:3
9Crack Detection in Pipes with Different Bend Angles Based on Ultrasonic Guided Wave显示文摘Pipeline plays an indispensable role in process industries,because the progressing crack-like defects of in it may result in serious accidents and significant economic losses.Therefore,it is essential to detect the cracks occurred in pipelines.The axial crack-like defects in elbows with different angle are inspected by using the T(0,1)mode guided waves,in which different configurations including 45°,90°,135°and 180°(straight pipe)are considered respectively.Firstly,the detection sensitivity for different defect location is experimentally investigated.After that,finite element simulation is used to explore the propagation behaviors of T(0,1)mode in different bend structures.Simulation and experiment results show that the crack in different areas of the elbow can affect the detection sensitivity.It can be found that the detection sensitivity of crack in the middle area of the elbow is higher compared to the extrados and intrados of the elbow.Finally,the mode conversion is also investigated when the T(0,1)crosses the bend,and the results show that bend is a key factor to the mode conversion phenomenon which presents between the T(0,1)mode and F(1,2)mode.Qi Minxin Chen Shaojie Zhou Shaoping Li Yong Jia Jiuhong 2017Transactions of Nanjing University of Aeronautics and Astronautics2017,34,3:3
10Compact and broadband multimode waveguide bend by shape-optimizing with transformation optics显示文摘Multimode waveguide bend is one of the key components for realizing high-density mode-division multiplexing systems on chip.However,the reported multimode waveguide bends are either large,bandwidth-limited or fabrication-complicated,which hinders their applications in future high-density multimode photonic circuits.Here we propose a compact multimode waveguide bend supporting four TE modes simply by shape-optimizing with transformation optics.The shape of the waveguide is optimized in the virtual space with gradient distribution of the refractive index,so that the scattering loss and intermode cross talk are well suppressed.After conformal mapping back into the physical space,a compact(effective radius of 17μm)multimode bending waveguide is obtained.Simulations show that the proposed multimode waveguide bend has little loss(<0.1 dB)and low cross talk(<−20 dB)throughout an ultrabroad wavelength range of 1.16–1.66μm.We also fabricated the shape-optimized multimode bending waveguide on a silicon-on-insulator wafer.At 1550 nm wavelength,the measured excess losses for the four lowest-order TE modes are less than 0.6 dB,and the intermode cross talks are all below−17 dB.Our study paves the way for realizing high-density and large-scale multimode integrated optical circuits for optical interconnect.SHUYI LI LIFENG CAI DINGSHAN GAO JIANJI DONG JIN HOU CHUNYONG YANG SHAOPING CHEN XINLIANG ZHANG 2020Photonics Research2020,8,12:3
11Distribution characteristics and its controlling factor of lacustrine high-quality source rocks in the Bozhong sag,Bohai Bay Basin显示文摘Distribution of Paleogene lacustrine high-quality source rocks in the Bozhong sag in Bohai Bay Basin is analyzed through data of geochemistry,geology and well logging,and its differences under the control of climate and tectonics is also well discussed.Distribution characteristics of the high-quality source rocks developed in the saline environment controlled by the climate are quite different from that developed in the rapid subsidence environment controlled by tectonics.The high-quality source rocks in Member 1 of Shahejie Formation developed in the saline environment account for 81.9%of total subsag area,and are distributed widely and extensively.The high-quality source rocks in Member 3 of Shahejie Formation and Member 3 of Dongying Formation is developed in the tectonic subsidence environment,and horizontally,the subsag subsidence rates has a positive correlation with the area proportion of the high-quality source rocks in the sag;vertically,the reduction-oxidation interface of the lake controls the enrichment of highquality source rocks.Controlled by the saline environment and rapid subsidence environment,the highquality source rocks in the Bozhong sag and adjacent areas have three types of development condition:the saline water,the tectonic subsidence,and joint control of the saline water and the tectonic subsidence.The humid climate and low subsidence rate are not favorable for development of high-quality source rocks.Hefeng Sun Lifang Liu Xue Jiang Shengbing Huang Mingyang Geng Shaoping Chen Nan Li Pu Shen 2019Petroleum Research2019,4,3:3
12A multicenter retrospective cohort study of ketogenic diet therapy in 481 children with infantile spasms显示文摘Background:Ketogenic diet(KD)therapy is one of the main treatments for drug-resistant epilepsy.However,the KD therapy has been applied in only a small number of infantile spasm cases.In this large multicenter study,we investigated the efficacy of KD therapy in the treatment of infantile spasms.Methods:In this retrospective,multicenter cohort study,clinical data from main epilepsy centers were analyzed.Patients were classified into different groups according to age,type of drug and whether glucocorticoid was used before initiation of KD.Results:From October 2014 to March 2020,481 patients(308 males and 173 females)with infantile spasms were treated with the KD therapy.The age of the patients ranged from 2 months to 20 years,with a mean age of 1 year and 10 months.The number of anti-seizure medications(ASMs)used before KD initiation ranged 0-6,with a median of 3.In different time from initiation(1,3,6,and 12 months),the rates of seizure freedom after KD were 6.9,11.6;16.0 and 16.8%,respectively(x^(2)=27.1772,P<0.0001).There was a significant difference in the rate of seizure freedom between 3 months and 1 month(x^(2)=6.5498,P=0.0105)groups,and 6 months and 3 months(x^(2)=3.8478,P=0.0498)groups,but not between 12 months and 6 months(x^(2)=0.1212,P=0.7278)groups.The rates of effectiveness were 44.7;62.8,49.1 and 32.0%(x^(2)=93.2674,P<0.0001),respectively.The retention rates were 94.0,82.5,55.7 and 33.1%(x^(2)=483.7551,P<0.0001),correspondingly.The rate of effectiveness and the retention rate of KD were significantly different among the 1,3,6 and 12 months.KD treatment was the first choice in 25 patients(5.2%),55 patients(11.4%)started KD after the failure of the first ASM,158 patients(32.8%)started KD after the failure of the second ASM,157 patients(32.6%)started KD after the failure of the third drug,and 86 patients(17.9%)started KD after the failure of the fourth and more.The KD effect was not related to the number of ASMs used before KD startup(P>0.05).Two hundred and eighteen patients(45.3%)failed to respond to corticotropin or glucocorticoid before initiation.There was no significant difference in the effectiveness rate at different time points between the group of KD therapy after glucocorticoid failure and the group after non-hormone failure (x^(2)=0.8613,P=0.8348).The rate of adverse events of KD in 1,3,6,and 12 months after KD initiation were 22.3,21.7,16.8 and 6.9%,respectively.The adverse events mainly occurred during the first 3 months of KD,and the main adverse events were gastrointestinal disturbance and constipation.Conclusions:The efficacy of the KD treatment for infantile spasms was not affected by age,medication,and glucocorticoid use before initiation.KD is one of the effective treatments for infantile spasms.Yuanzhen Ye Dan Sun Hua Li Jianmin Zhong Rong Luo Baomin Li Dengna Zhu Dan Li Shaoping Huang Yuwu Jiang Nong Xiao Yucai Chen Yuqin Zhang Mei Yu Xiaoyun Shen Li Gao Guo Zheng Congmin Zhao Baoqiang Yuan Jianxiang Liao Jiong Qin CAAE KD group 2022Acta Epileptologica2022,5,1:2
13Effect of Migration on Children's Self-esteem in Rural China显示文摘China's rapid economic growth has been facilitated by its large volume of rural to urban migration.China's projected future development,especially increasing urbanization,implies that such migration will further intensify.However,migration does not come without cost.There are concerns about the potential negative impacts of migration on children 's care,education,and,in particular,the self-esteem of children left behind in villages where one or both parents have out-migrated to cities.In this paper,we employ unique survey data collected from Shaanxi Province,where more than 4700 ninth grade students from 36 rural junior high schools in five counties were surveyed in late 2011.The results show that having both parents migrate into cities significantly reduced children 's self-esteem.The effects are also gender sensitive.Girls that had a father or both parents who had out-migrated were inclined to have lower self-esteem than boys.Moreover,our study findings indicate that parental migration decreased children 's self-esteem more for individuals with initial low self-esteem.Xuefeng Zhan Shaoping Li Chengfang Liu Linxiu Zhang 2014China & World Economy2014,22,4:2
14The analysis of trans fatty acid profiles in deep frying palm oil and chicken fillets with an improved gas chromatography method显示文摘Yi Chen Ying Yang Shaoping Nie Xi Yang Yuting Wang Meiyan Yang Chang Li Mingyong Xie 2014Food Control2014,,:2
15Pipelines vibration analysis and control based on clamps'locations optimization of multi-pump system显示文摘The violent vibration of hydraulic pipelines in aircraft may cause faults or even an accident,especially for the large aircraft with the multi-pump system because of different vibration sources and complex pipelines system.Aiming to the vibration analysis and control of the multipump system,this paper proposed the clamps’locations optimization to minimize the system impedance at vibration frequencies.Firstly,the models of the flexible clamp and other components in multi-pump system were established,based on which,the system impedance was calculated by using Transfer Matrix Method(TMM);Secondly,the objective function is defined as weighted sum of system impedance at frequencies of different vibration sources.Then,the clamps’locations were altered to change the system impedance.Moreover,The Chaotic Swarm Particle Optimization(CPSO)algorithm was applied to obtain the optimal clamps’locations and the minimum value of objective function which decreased by 36.4%compared to the value of original clamps’locations;Finally,the experiments from vibration and pressure test with original and optimized clamps’locations verified the effectiveness of the system impedance calculation and clamps’locations optimization method.Xin LI Weihao LI Jian SHI Qiang LI Shaoping WANG 2022Chinese Journal of Aeronautics2022,35,6:2
16Risks of maternal prepregnancy overweight/obesity, excessive gestational weight gain, and bottle-feeding in infancy rapid weight gain: evidence from a cohort study in China显示文摘Rapid weight gain(RWG) in infants is associated with numerous health problems, and its risk factors are still unclear. We assessed 98,097 maternal-infant pairs from a population-based cohort study and followed up with them until the infants were6 months old. We assessed the associations between maternal prepregnancy weight status;gestational weight gain;feeding pattern;and infants’ RWG at 0–1, 0–3, 1–3, and 3–6 months using multivariate unconditional logistic regression models, with controlled confounders. We found that maternal prepregnancy weight status, gestational weight gain, and feeding pattern at the1 st, 3 rd, and 6 th months had significant impacts on the infants’ RWG at each time period(P<0.05). Infants with overweight/obese mothers had a higher risk of RWG after birth, whereas those of mothers who experienced excessive gestational weight gain had higher risks of RWG from birth than the other groups(P<0.01). Infants who were formula-fed had a higher risk of RWG than breastfed infants at the same time point(P<0.01). In conclusion, maternal prepregnancy obesity, excessive gestational weight gain, and formula-feeding were risk factors for infants’ RWG during the first 6 months of life.Shaoping Yang Hong Mei Hui Mei Yan Yang Na Li Yafei Tan Yiming Zhang Dan Zhang Yan Zhang An’na Peng Bin Zhang 2019Science China(Life Sciences)2019,62,12:2
17Erosion degradation characteristics of a linear electro-hydrostatic actuator under a high-frequency turbulent flow field显示文摘The paper proposes a performance degradation analysis model based on dynamic erosion wear for a novel Linear Electro-Hydrostatic Actuator(LEHA). Rather than the traditional statistical methods based on degradation data, the method proposed in this paper firstly analyzes the dominant progressive failure mode of the LEHA based on the working principle and working conditions of the LEHA. The Computational Fluid Dynamics(CFD) method, combining the turbulent theory and the micro erosion principle, is used to establish an erosion model of the rectification mechanism. The erosion rates for different port openings, under a time-varying flow field, are obtained. The piecewise linearization method is applied to update the concentration of contaminated particles within the LEHA, in order to gain insight into the erosion degradation process at various stages of degradation. The main contribution of the proposed model is the application of the dynamic concentration of contamination particles in erosion analysis of Electro-Hydraulic Servo Valves(EHSVs), throttle valves, spool valves, and needle valves. The effects of system parameters and working conditions on component wear are analyzed by simulations. The results of the proposed model match the expected degradation process.Yuan LI Shaoping WANG Mileta M.TOMOVIC Chao ZHANG 2018Chinese Journal of Aeronautics2018,31,5:2
18Sexually disrupting effects of nonylphenol and diethylstilbestrol on male silver carp ( Carassius auratus ) in aquatic microcosms显示文摘Lihua Yang Li Lin Shaoping Weng Zhiqin Feng Tiangang Luan 2008Ecotoxicology and Environmental Safety2008,,2:2
19Enhanced complete photonic bandgap in a moderate refractive index contrast chalcogenide-air system with connected-annular-rods photonic crystals显示文摘Connected-annular-rods photonic crystals(CARPCs) in both triangular and square lattices are proposed to enhance the two-dimensional complete photonic bandgap(CPBG) for chalcogenide material systems with moderate refractive index contrast. For the typical chalcogenide-glass–air system with an index contrast of 2.8:1, the optimized square lattice CARPC exhibits a significantly larger normalized CPBG of about 13.50%, though the use of triangular lattice CARPC is unable to enhance the CPBG. It is almost twice as large as our previously reported result [IEEE J. Sel. Top. Quantum Electron. 22, 4900108(2016)]. Moreover, the CPBG of the square-lattice CARPC could remain until an index contrast as low as 2.24:1. The result not only favors wideband CPBG applications for index contrast systems near 2.8:1, but also makes various optical applications that are dependent on CPBG possible for more widely refractive index contrast systems.JIN HOU CHUNYONG YANG XIAOHANG LI ZHENZHOU CAO SHAOPING CHEN 2018Photonics Research2018,6,4:2
20The Rapid Determination of Artemisinin by Post-column Derivatization High Performance Liquid chromatography Using Matrix Solid Phase Dispersion Method显示文摘Hongcheng Liu Qiwan Li Shaoping Li 2008Journal of Chromatographic Science2008,46,2:1
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