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| 1 | Genetic Structure and Diversity of Parental Cultivars Involved in China Mainland Sugarcane Breeding Programs as Inferred from DNA Microsatellites显示文摘To understand genetic structure and diversity of parental cultivars involved in China Mainland sugarcane breeding programs,92 elite parents and 4 wild relatives were genotyped with 18 microsatellite DNA markers.The genetic similarity(GS) values among the cultivars ranged from 0.346 to 0.960 with an average of 0.533.Among the introduced cultivars,India accessions had the closest genetic distance to China Mainland accessions(0.447),while Australia accessions have the furthest distance(0.503).A comparison of allelic diversity among geographical origins showed that there were 22 China Mainland specific alleles,of which 28% were derived from native S.spontaneaum germplasm in China.Model-based genetic structure,clustering,and principal components analyses consistently revealed there were five groups within the 96 accessions.Groups 1,2,4,and 5 consisted of all cultivars and group 3 only contained wild germplasm.Group 2 was characterized as the Introduction group with 46 cultivars predominantly introduced from Australia,Taiwan of China,India,and USA.Groups 1,4,and 5 consisted of cultivars mostly originated from China Mainland,defined as the Complex group,Yacheng lines group,and F134/CP72-1210 group,respectively,upon their pedigree.By understanding the genetic relationships among the parental cultivars,breeders can gain a rational basis for expanding the gene pool and select the best parental accessions for crossing. | QI Yong-wen PAN Yong-bao LAO Fang-ye ZHANG Chui-ming FAN Li-na HE Hui-yi LIU Ruin WANG Qin-nan LIU Shao-mou LIU Fu-ye LI Qi-wei DENG Hai-hua | 2012 | Journal of Integrative Agriculture2012，11，11： | 6 |
| 2 | Extremely low penetrance of deafness associated with the mitochondrial 12S rRNA mutation in 16 Chinese families: Implication for early detection and prevention of deafness显示文摘 | Pu Dai Xin Liu Dongyi Han Yaping Qian Deliang Huang Huijun Yuan Weiming Li Fei Yu Ruining Zhang Hongyan Lin Yong He Youjun Yu Quanzhu Sun Huaiyi Qin Ronghua Li Xin Zhang Dongyang Kang Juyang Cao Wie-Yen Young Min-Xin Guan | 2005 | Biochemical and Biophysical Research Communications2005，，1： | 2 |
| 3 | Constituents of the flowers of Punica granatum显示文摘 | Rufeng Wang Wei Wang Liang Wang Ruining Liu Yi Ding Lijun Du | 2006 | Fitoterapia2006，，7： | 1 |
| 4 | A microcalorimetric method for studying the biological effects of La^3+ on Escherichia coli 显示文摘 | Zhao Ruining Liu Yi Xie Zhlxiong | 2000 | Biochem Biophys Methods2000，46，： | 1 |
| 5 | Research progress on corrosion behaviors and biocompatibility of rare-earth magnesium alloys in vivo and in vitro显示文摘As yet,Mg alloys acting as the medical implants have drawn extensive attention,due to their spontaneous degrada bility,effective load-transmissibility and the excellent biocompatibility,particularly in bone tissue reconstruction and vascular radial-support.Regrettably,they were inevitably affected by the tension/compression-torsion,dynamic erosion and corrosion fatigue under complex service conditions,which lead to premature failure of implantation-materials.Micro-alloying addition is an effective way to delay the rapid degradation,especially in rare-earth micro-composite addition.It can not only reduce intensities of galvanic-corrosion by refining the grain sizes and adjusting the Volta-potentials distribution of the precipitates,but also modify the compositions and biocompatibility of the degradation products.Moreover,the higher compress tress on the surface can improve the stability and densification of the film layer,which enhanced the corrosion resistance.Thus,the latest research progress about in vivo/vitro degradation behavio rs and bioco mpatibility of rare-earth Mg alloys is reviewed;The internal relationships between rare-earth elements,phase features and degradation behaviors of Mg alloys are summarized.Moreover,the effects of rare-earth addition on the film-characteristics are deeply explained,and the induced mechanisms of rare earth elements on the biocompatibility are revealed. | Yuan Zhang Yun Liu Ruining Zheng Yaqi Zheng Liansheng Chen | 2023 | Journal of Rare Earths2023，41，12： | 0 |
| 6 | Effects of Cadmium on the Energy Metabolism of Isolated Hepatocytes: Its Relationship with the Nonviability of Isolated Hepatocytes Caused by Cadmium显示文摘The effects of cadmium on the energy metabolism of mitochondria were studied with isolated hepatocytes and rat liver mitochondria. It was found that cadmium inhibited the respiration of both isolated hepatocytes and mitochondria and decreased the ATP content of isolated hepatocytes. This inhibition of energy metabolism of mitochondria was highly related to the nonviability of isolated hepatocytes caused by cadmium. The site of electron transport of the mitochondrial respiratory chain blocked by cadmium was located between cytochrome b and flavoproteins. The uncoupling effects of mitochondrial oxidative phosphorylation caused by cadmium may have resulted from changes in the fluidity and permeability of the mitochondrial membrane. (c) 1990 Academic Press. Inc. | LIU RUINING AND LIU YUGU Department of Environmental Toxicology, Tongji Medical University, Wuhan, Hubei Province, China | 1990 | Biomedical and Environmental Sciences1990，3，3： | 0 |
| 7 | Clinical features of 162 fatal cases of COVID-19:a multi-center retrospective study显示文摘Background:The coronavirus disease 2019(COVID-19)has affected approximately 2 million individuals worldwide;however,data regarding fatal cases have been limited.Objective:To report the clinical features of 162 fatal cases of COVID-19 from 5 hospitals in Wuhan between December 30,2019 and March 12,2020.Methods:The demographic data,signs and symptoms,clinical course,comorbidities,laboratory findings,computed tomographic(CT)scans,treatments,and complications of the patients with fatal cases were retrieved from electronic medical records.Results:The median patient age was 69.5(interquartile range:63.0–77.25)years,and 80%of the patients were over 61 years.A total of 112(69.1%)patients were men.Hypertension(45.1%)was the most common comorbidity,while 59(36.4%)patients had no comorbidity.At admission,131(81.9%)patients had severe or critical COVID-19,whereas 39(18.1%)patients with hypertension or chronic lung disease had moderate COVID-19.In total,126(77.8%)patients received antiviral treatment,while 132(81.5%)patients received glucocorticoid treatment.A total of 116(71.6%)patients were admitted to the intensive care unit(ICU),and 137(85.1%)patients received mechanical ventilation.Most patients received mechanical ventilation before ICU admission.Approximately 93.2%of the patients developed respiratory failure or acute respiratory distress syndrome.There were no significant differences in the inhospital survival time among the hospitals(P=0.14).Conclusion:Young patients with moderate COVID-19 without comorbidity at admission could also develop fatal outcomes.The in-hospital survival time of the fatal cases was similar among the hospitals of different levels in Wuhan. | Xianlong Zhou Guoyong Ding Qing Fang Jun Guo Luyu Yang Ping Wang Shou-Zhi Fu Ang Li Jian Xia Jiangtao Yu Jianyou Xia Min Ma Zhuanzhuan Hu Lei Huang Ruining Liu Cheng Jiang Shaoping Li Mingxia Yu Xizhu Xu Yan Zhao Quan Hu Weijia Xing Zhigang Zhao | 2022 | Emergency and Critical Care Medicine2022，2，3： | 0 |
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