|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Spatial and temporal variability in the net primary production of alpine grassland on the Tibetan Plateau since 1982显示文摘基于 GIMMS AVHRR NDVI 数据( 8 km 空间分辨率)为 19822000 , SPOT 植被 NDVI 数据( 1 km 空间分辨率)为 19982009 ,并且观察植物生物资源数据, CASA 模型习惯于在高山的草地的变化在西藏的高原( TP )上让主要生产( NPP )赚的模型。这研究将帮助评估高山的草地生态系统的健康条件,并且对高原牧场并且到 TP 上的国家生态的安全躲蔽处的函数的理解的持续开发的提升很重要。NPP 变化的时间空间的特征用空间统计分析被调查,独立根据 physico 地理的因素(自然地区,高度,纬度和经度) ,河盆,和县级的行政区域。处理的数据用一个 ENVI 4.8 平台被执行,当一个 ArcGIS 9.3 和 ANUSPLIN 平台被用来进行空间分析并且印射时。主要结果如下:(1 ) TP 上的高山的草地的 NPP 逐渐地从东南减少到西北,它在降水和温度对应于坡度。从 1982 ~ 2009,在 TP 高山的草地的平均年度全部的 NPP 是 177.2 ?? ?? ? | ZHANG Yili QI Wei ZHOU Caiping DING Mingjun LIU Linshan GAO Jungang BAI Wanqi WANG Zhaofeng ZHENG Du | 2014 | Journal of Geographical Sciences2014，24，2： | 47 |
| 2 | Assessment of diurnal variation of summer precipitation over the Qilian Mountains based on an hourly merged dataset from 2008 to 2014显示文摘调查日报在在向东北西藏的高原的 Qilian 山的夏天降水的变化,时时,为这个区域的降水数量在 0.1 点用一个时时合并的降水产品在 2008-2014 的夏天期间被分析 ? 湵慦潶慲汢? 諟D禎澞?汣浩瑡 ? 档湡敧椠?? | LIU Xuemei ZHANG Mingjun WANG Shengjie WANG Jie ZHAO Peipei ZHOU Panpan | 2017 | Journal of Geographical Sciences2017，27，3： | 14 |
| 3 | Tartrate-resistant acid phosphatase 5b is a potential biomarker for rheumatoid arthritis: a pilot study in Han Chinese显示文摘 | Cheng Tao Wang Mingjun Chen Zhiwei Robert A Eisenberg Zhang Yu Zou Yaohong Deng Yingsu Wang Mian Zhou Ling | 2014 | Chinese Medical Journal2014，，16： | 7 |
| 4 | The methylenetetrahydrofolate reductase genotype 677CT and non-alcoholic fatty liver disease have a synergistic effect on the increasing homocysteine levels in subjects from Chongqing,China显示文摘The methylenetetrahydrofolate reductase(MTHFR)genotypes 677CT and 677TT are associated with elevated serum homocysteine(Hcy)levels by means of lowering the activity of MTHFR,and the increase in serum Hcy may be linked to increased susceptibility to nonalcoholic fatty liver disease(NAFLD).However,there are contradictory reports of the relationship among the MTHFR 677CT gene polymorphism,Hcy,and NAFLD.Therefore,the aim of this study was to identify potential associations and interactions of either Hcy levels or the MTHFR 677CT gene polymorphism with the susceptibility to NAFLD in a Chinese population.The association between the MTHFR 677 CT gene polymorphism and Hcy levels was determined in 243 subjects with NAFLD and 388 healthy subjects without NAFLD using polymerase chain reactionrestriction fragment length polymorphism analysis and high-performance liquid chromatography.In subjects with NAFLD,there was no statistical difference in the genotypic and allelic frequencies of the MTHFR 677 CT gene polymorphism,while serum Hcy levels were significantly higher in subjects with NAFLD.Furthermore,these results strongly suggest that the MTHFR 677CT gene polymorphism and NAFLD have a potential synergistic effect on Hcy elevation,although the MTHFR 677CT gene polymorphism was not correlated with NAFLD in a Chinese population. | Xiaolin Wang Yongli Zhou Mingjun Zhang Yonghong Wang Bo Qin | 2019 | Genes & Diseases2019，6，1： | 6 |
| 5 | Estimation of correction coefficients for measured coal bed methane contents显示文摘Improving the accuracy and precision of coal bed methane(CBM) estimates requires correction of older data from older coal exploration surveys to newer standards.Three methods,the depth gradient method,the contour aerial weight method,and the well-point aerial weight method,were used to estimate the correction coefficient required to predict CBM gas content from coal exploration data.The data from the Nos.3 and 15 coal seams provided the coal exploration data while the CBM exploration stages within the X1 well block located in the southern part of the Qinshui Basin provided the data obtained using newer standards.The results show the correction coefficients obtained from the two aerial weight methods are similar in value but lower than the one obtained from the depth gradient method.The three methods provide similar results for the Nos.3 and 15 seams in that the correction factor is lower for the former seam.The results from the depth gradient method taken together with the coal seam burial depth and the coal rank suggest that variations in the correction factor increase linearly along with coal seam burial depth and coal rank.The correlation obtained can be applied to exploration and the evaluation of coal bed gas resources located in coalfields. | Lei Bo Fu Xuehai Zhou Baoyan Shen Jia ZOU Mingjun Feng Qing | 2012 | International Journal of Mining Science and Technology2012，22，4： | 5 |
| 6 | Effects of climate,land use and land cover changes on soil loss in the Three Gorges Reservoir area,China显示文摘Climate,land use and land cover(LULC)changes are among the primary driving forces of soil loss.Decoupling their effects can help in understanding the magnitude and trend of soil loss in response to human activities and ecosystem management.Here,the RUSLE model was applied to estimate the spatial-temporal variations of soil loss rate in the Three Gorges Reservoir(TGR)area during 2001-2015,followed by a scenario design to decouple the effects of climate and LULC changes.The results showed that increasing rainfall generated as much as 2.90×10^(7)t soil loss in the TGR area.However,such effect was offset by changes in LULC particularly afforestation,which retained about 1.10×10^(7)t soil annually.Other human activities such as dam development and urbanization aggravated soil loss by as much as 1.40×10^(6)t annually.Because of land use policies that favor economic development,distinct spatial variances of soil loss were observed in TGR area.Soil loss in some counties located downstream of the TGR area(i.e.,close to the dam)was more influenced by dam development,but soil loss in the other counties was more influenced by urbanization.As climate change(i.e.,increasing rainfall)did not affect plant performance in TGR area,our findings suggested that ecological restoration was more beneficial to curb the amount of soil loss caused by urbanization and dam construction. | Chunbo Huang Zhixiang Zhou Mingjun Teng Changguang Wu Pengcheng Wang | 2020 | Geography and Sustainability2020，1，3： | 3 |
| 7 | The FMEDA Based DC Calculation for Railway Safety Computer显示文摘This paper presents a new algorithm to compute the Diagnostic coverage(DC) for railway safety computer using the Failure modes effects and diagnostic analysis(FMEDA) theory. The importance to work out the DC accurately is stressed. A certain type of railway safety computer's output element is taken as an example to show how the DC is worked out using the FMEDA method. The probability of dangerous failures per hour(PFH) of one certain safety computer is obtained considering the DC.The final results show that the DC is 99.6% and the PFH of the safety is 1.165 fit, which means 1.165 dangerous failures may occur during 1 billion hours' working time,running up to the requirement of the Safety integrity level4(SIL4). This paper provides an example to come up with the DC for safety computer, thus making the PFH calculation more accurate and so is the Safety integrity level. | WANG Juhan GAO Ying CAO Yuan TANG Tao ZHOU Mingjun | 2020 | Chinese Journal of Electronics2020，29，2： | 2 |
| 8 | Synthesis and Tribological Properties of Graphene-Copper Nanoparticle Composites as Lithium Grease Additive显示文摘In this paper, the graphene-copper nanoparticle composites(GN/Cu NPs) were prepared by in situ chemical reduction in aqueous solution. The influence of pH value and the concentration of PVP on the particle size and structure of the GN/Cu NPs as well as the element distribution were analyzed via the scanning electron microscopy(SEM), the transmission electron microscopy(TEM), the X-ray diffraction(XRD), and the energy dispersive spectroscopy(EDS). The tribological properties of the grease with GN/Cu NPs composites have been studied by SRV-IV. It was found that compared to the base grease, the GN/Cu NPs composites could help to reduce the wear loss of the disk by 85.5% and the average friction coefficient by 15.5%. The test results clearly indicated that the addition of the GN/Cu NPs composites significantly enhanced the tribological properties of grease. | Wang Jing Guo Xiaochuan He Yan Jiang Mingjun Zhou Weigui | 2017 | China Petroleum Processing & Petrochemical Technology2017，19，4： | 2 |
| 9 | Overpotential-dependent shape evolution of gold nanocrystals grown in a deep eutectic solvent显示文摘这份报纸报导在胆碱氯化物脲(ChCl 脲) 的金 nanocrystals (Au NC ) 的过电位依赖者形状进化基于深最容易溶解的溶剂(DES ) 。生长过电位在调节 Au NC 的形状起一个关键作用,这被发现。Au NC 的形状进化连续地从凹面菱形的 dodecahedra (RD ) 到凹面立方体,八足类动物, cuboctahedral 盒子,并且最后,到空 octahedra (哦) 被小心地从 -0.50 在范围控制生长过电位到 -0.95 V 完成(对磅伪参考电极) 。另外,脲的存在在 Au NC 的形状进化是重要的。同样准备的 Au NC 的表面结构被扫描电子显微镜学(SEM ) 包括地描绘,传播电子显微镜学(TEM ) 和电气化学的研究。为 D 葡萄糖 electrooxidation 的同样准备的 Au NC 的 electrocatalytic 活动易感知地依赖于他们的形态学,这被表明。说明的结果使脱氢的葡萄糖在凹面 RD 和凹面上吸附了立方的 Au NC,这优先地在低电极潜力被转变到 gluconolactone。随后的 gluconolactone 氧化在八足类动物上有利地发生了与 { 111 } 截断的手臂并且空在高电极潜力的 OH。这研究开创一条新途径由把 DES 与电气化学的技术相结合开发 Au NC 的 surface-structurecontrolled 生长。另外,它为调节 NC 的 electrocatalytic 性质是重要的。 | Lu Wei Bangan Lu Mingjun Sun Na Tian Zhiyou Zhou Binbin Xu Xinsheng Zhao Shigang Sun | 2016 | Nano Research2016，9，11： | 2 |
| 10 | DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bd-2 inhibitors显示文摘Objective:Mcl-1 overexpression confers acquired resistance to Bcl-2 inhibitors in non-small cell lung cancer(NSCLC),but no direct Mcl-1 inhibitor is currently available for clinical use.Thus,novel therapeutic strategies are urgently needed to target Mcl-1 and sensitize the anti-NSCLC activity of Bcl-2 inhibitors.Methods:Cell proliferation was measured using sulforhodamine B and colony formation assays,and apoptosis was detected with Annexin V-FITC staining.Gene expression was manipulated using siRNAs and plasmids.Real-time PCR and Western blot were used to measure mRNA and protein levels.Immunoprecipitation and immunofluorescence were used to analyze co-localization o f dual specificity tyrosine-phosphorylation-regulated kinase 1A(DYRK1A)and Mcl-1.Results:Suppression of DYRK1A resulted in reduced Mcl-1 expression in NSCLC cells,whereas overexpression of DYRK1A significantly increased Mcl-1 expression.Suppression of DYRK1A did not alter Mcl-1 mRNA levels,but did result in an accelerated degradation o f Mcl-1 protein in NSCLC cells.Furthermore,DYRK1A mediated proteasome-dependent degradation o f Mcl-1 in NSCLC cells,and DYRK1A co-localized with Mcl-1 in NSCLC cells and was co-expressed with Mcl-1 in tumor samples from lung cancer patients,suggesting that Mcl-1 may be a novel DYRK1A substrate.We showed that combined therapy with harmine and Bcl-2 antagonists significantly inhibited cell proliferation and induced apoptosis in NSCLC cell lines as well as primary NSCLC cells.Conclusions:Mcl-1 is a novel DYRK1A substrate,and the role of DYRK1A in promoting Mcl-1 stability makes it an attractive target for decreasing Bcl-2 inhibitor resistance. | Yangling Li Dongmei Zhou Shuang Xu Mingjun Rao Zuoyan Zhang Linwen Wu Chong Zhang Nengming Lin | 2020 | Cancer Biology & Medicine2020，17，2： | 2 |
| 11 | An atlas of CNV maps in cattle, goat and sheep显示文摘Copy number variation(CNV)is the most prevalent type of genetic structural variation that has been recognized as an important source of phenotypic variation in humans,animals and plants.However,the mechanisms underlying the evolution of CNVs and their function in natural or artificial selection remain unknown.Here,we generated CNV region(CNVR)datasets which were diverged or shared among cattle,goat,and sheep,including 886 individuals from 171 diverse populations.Using 9 environmental factors for genome-wide association study(GWAS),we identified a series of candidate CNVRs,including genes relating to immunity,tick resistance,multi-drug resistance,and muscle development.The number of CNVRs shared between species is significantly higher than expected(P<0.00001),and these CNVRs may be more persist than the single nucleotide polymorphisms(SNPs)shared between species.We also identified genomic regions under long-term balancing selection and uncovered the potential diversity of the selected CNVRs close to the important functional genes.This study provides the evidence that balancing selection might be more common in mammals than previously considered,and might play an important role in the daily activities of these ruminant species. | Yongzhen Huang Yunjia Li Xihong Wang Jiantao Yu Yudong Cai Zhuqing Zheng Ran Li Shunjin Zhang Ningbo Chen Hojjat Asadollahpour Nanaei Quratulain Hanif Qiuming Chen Weiwei Fu Chao Li Xiukai Cao Guangxian Zhou Shudong Liu Sangang He Wenrong Li Yulin Chen Hong Chen Chuzhao Lei Mingjun Liu Yu Jiang | 2021 | Science China(Life Sciences)2021，64，10： | 2 |
| 12 | Multipurpose greenway planning for changing cities: a framework integrating priorities and a least-cost path model 显示文摘 | TENG Mingjun WU Changguang ZHOU Zhixiang | 2011 | Landsc Urban Plan2011，103，1： | 1 |
| 13 | Optimization of deep penetration laser welding of thick stainless steel with a 10 kW fiber laser显示文摘 | Mingjun Zhang Genyu Chen Yu Zhou | 2014 | Materials and Design2014，，53： | 1 |
| 14 | Research Progress of Aromatherapy in the Treatment of Obesity显示文摘Obesity is a common clinical disease,in order to take a healthy and simple way to treat it,the volatile properties of traditional Chinese medicine play a role in lifting weights.Aromatherapy uses the four qi and five flavors of traditional Chinese medicine as a typical representative.In order to explore the mechanism of action of aromatherapy in depth,through the etiology and pathogenesis of obesity,the historical origin of modern times,related organs,pathogenesis,and the research progress of aromatherapy in the treatment of obesity,the classification of aromatherapy,and the related research of aromatic drugs,it is found that aromatherapy has a large number of significant clinical effects in modern times.It can be used to treat obesity independently under the guidance of the basic theory of Chinese medicine,and can also be combined with other Chinese medicines to form prescription drug treatment,and in combination with other ways to treat obesity.However,at present,this method of treating obesity has not received widespread attention,and it still needs to be studied and promoted by scholars. | Xiaochao GANG Yang CHEN Mingjun LIU Jie LIU Xiaobo JIANG Hanrong QU Qijue LIANG Jiashu ZHOU Yuening DONG | 2022 | Medicinal Plant2022，13，4： | 1 |
| 15 | Direct observation of keyhole characteristics in deep penetration laser welding with a 10 kW fiber laser显示文摘 | Mingjun Zhang Genyu Chen Yu Zhou | 2013 | Optical Society of America2013，21，17： | 1 |
| 16 | A nuclear localized protein ZCCHC9 is expressed in cerebral cortex and suppresses the MAPK signal pathway显示文摘The CCHC-type zinc finger motif has numerous biological activities (such as DNA binding and RNA binding) and can also mediate protein-protein interaction. This article gives a primary report about the human ZCCHC9 gene. Protein ZCCHC9 contains four CCHC motifs and is highly conserved in humans, mice, and rats. The whole cDNA sequence of the ZCCHC9 gene has been amplified by PCR and a number of plasmids have been constructed for further study. The results show that ZCCHC9 is localized in the nucleus, and especially concentrated in the nucleolus. It is highly expressed in the brain and testicles of the mouse. This has been confirmed by real-time reverse transcription polymerase chain reaction (RT-PCR). In situ hybridization of the mouse brain indicates that ZCCHC9 is mainly expressed in the cerebral cortex. Reporter gene assay shows that ZCCHC9 suppresses the transcription activities of NF-kappa B and SRE, and may play roles in the Mitogen-Activated Protein Kinase (MAPK) signaling transduction pathway. | Aidong Zhou Jianlin Zhou Liping Yang Mingjun Liu Hong Li Su Xu Mei Han Jian Zhang | 2008 | Journal of Genetics and Genomics2008，35，8： | 1 |
| 17 | Energy Minimization Method for Scattered Data Hermite Interpolation 显示文摘 | ZHOU Tianhe HAN Danfu LAI Mingjun | 2008 | Applied Numerical Mathematics2008，58，： | 1 |
| 18 | Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model显示文摘Severe acute respiratory syndrome coronavirus 2(SARSCo V-2)infection can result in more severe syndromes and poorer outcomes in patients with diabetes and obesity.However,the precise mechanisms responsible for the combined impact of coronavirus disease 2019(COVID-19)and diabetes have not yet been elucidated,and effective treatment options for SARS-Co V-2-infected diabetic patients remain limited.To investigate the disease pathogenesis,K18-h ACE2 transgenic(h ACE2^(Tg))mice with a leptin receptor deficiency(h ACE2-Lepr^(-/-))and high-fat diet(h ACE2-HFD)background were generated.The two mouse models were intranasally infected with a 5×10^(5) median tissue culture infectious dose(TCID_(50))of SARSCo V-2,with serum and lung tissue samples collected at 3days post-infection.The h ACE2-Lepr^(-/-)mice were then administered a combination of low-molecular-weight heparin(LMWH)(1 mg/kg or 5 mg/kg)and insulin via subcutaneous injection prior to intranasal infection with1×10^(4) TCID_(50)of SARS-Co V-2.Daily drug administration continued until the euthanasia of the mice.Analyses of viral RNA loads,histopathological changes in lung tissue,and inflammation factors were conducted.Results demonstrated similar SARS-Co V-2 susceptibility in h ACE2^(Tg)mice under both lean(chow diet)and obese(HFD)conditions.However,compared to the h ACE2-Lepr^(+/+)mice,h ACE2-Lepr^(-/-)mice exhibited more severe lung injury,enhanced expression of inflammatory cytokines and hypoxia-inducible factor-1α(HIF-1α),and increased apoptosis.Moreover,combined LMWH and insulin treatment effectively reduced disease progression and severity,attenuated lung pathological changes,and mitigated inflammatory responses.In conclusion,preexisting diabetes can lead to more severe lung damage upon SARS-Co V-2 infection,and LMWH may be a valuable therapeutic approach for managing COVID-19patients with diabetes. | Zhongyun Zhang Ning Zhang Xuancheng Lu Min Zhou Xiaoxiang Yan Weiqiong Gu Jingru Yang Qin Zhang Cheng Zhang Yuhuan Gong Mingjun Jia Xiaoyu Zhang Peng Ning Mei Liu Xiaoyan Li Xiaomeng Shi Wenjun Liu George FGao Guang Ning Jiqiu Wang Yuhai Bi | 2023 | Zoological Research2023，44，6： | 1 |
| 19 | Multipurpose greenway planning for changing cities: A framework integrating priorities and a least-cost path model显示文摘 | TENG Mingjun WU Changgnang ZHOU Zhixiang | 2011 | Landscape Urban Plan2011，103，1： | 1 |
| 20 | Multipurpose greenway planning for changing cities: A framework integrating priorities and a least-cost path model显示文摘 | Mingjun Teng Changguang Wu Zhixiang Zhou Elizabeth Lord Zhongming Zheng | 2011 | Landscape and Urban Planning2011，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员