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28篇 您的检索式:作者名="Yuling Peng"
    题名 作者 年代 出处 被引量
1The bHLH Transcription Factor MYC3 Interacts with the Jasmonate ZIM-Domain Proteins to Mediate Jasmonate Response in Arabidopsis显示文摘Arabidopsis Jasmonate ZIM 域蛋白质(JAZ ) 充当复杂的 SCFCOI1 的底层镇压他们的下游地指向,它为调整 JA 的植物开发和防卫是必要的。bHLH 抄写因素 MYC2 被发现 JA 回答包括与 JAZ 交往并且调停 JA 禁止的根生长。这里,我们识别了直接由它的 N 终端区域的优点与 JAZ 交往了调整 JA 回答的另一 bHLH 抄写因素 MYC3。有 MYC3 的 overexpression 的转基因的植物在 JA 禁止的根延伸和幼苗开发展出了超敏性。交往 JAZ 模式和 MYC3 的导致 JA 的表示模式从 MYC2 的那些是可区分的。我们推测那 MYC3, MYC2 可以在 JA 回答的规定有冗余而且可区分的功能。Zhiwei Cheng Li Sun Tiancong Qi Bosen Zhang Wen Peng Yule Liu Daoxin Xie 2011Molecular Plant2011,4,2:35
2Regulation of the inflammatory cycle by a controllable release hydrogel for eliminating postoperative inflammation after discectomy显示文摘Surgery is the final choice for most patients with intervertebral disc degeneration(IDD).Operation-caused trauma will cause inflammation in the intervertebral disc.Serious inflammation will cause tissue defects and induce tissue degeneration,IDD recurrence and the occurrence of other diseases.Therefore,we proposed a scheme to treat recurrence after discectomy by inhibiting inflammation with an aspirin(ASP)-loaded hydrogel to restore the mechanical stability of the spine and relieve local inflammation.ASP-liposomes(ASP-Lips)were incorporated into a photocrosslinkable gelatin-methacryloyl(GelMA)via mixing.This material can effectively alleviate inflammation by inhibiting the release of high mobility group box 1(HMGB1)from the nucleus to the cytoplasm.We further assessed the expression of inflammatory cytokines,such as interleukin 6(IL-6)and tumor necrosis factor-α(TNF-α),and degeneration-related factors,such as type II collagen(COL-2),Aggrecan,matrix metallopeptidases-3(MMP-3),MMP-13,a disintegrin and metalloproteinase with thrombospondin motifs-4(ADAMTS-4)and ADAMTS-5 in rat nucleus pulpous cells.The level of IDD was analyzed through H&E,safranin-O staining and immunohistochemistry in rabbit samples.In vitro,we found that ASP-Lip@GelMA treatment significantly decreased inflammatory cytokines,MMP-3 and-13,and ADAMTS-4 and-5 and up-regulated COL-2 and Aggrecan via the inhibited release of HMGB-1 from the nucleus.In vivo,ASP-Lip@GelMA can effectively inhibit inflammation of local tissue after disc surgery and fill local tissue defects.This composite hydrogel system is a promising way to treat the recurrence of IDD after surgery without persistent complications.Yu Liu Jiacheng Du Peng Peng Ruoyu Cheng Jiayi Lin Congxin Xu Huilin Yang Wenguo Cui Haiqing Mao Yuling Li Dechun Geng 2021Bioactive Materials2021,6,1:6
3Travel Behaviours of Sharing Bicycles in the Central Urban Area Based on Geographically Weighted Regression: The Case of Guangzhou, China显示文摘Mobile information and communication technologies(MICTs) have fully penetrated everyday life in smart societies;this has greatly compressed time, space, and distance, and consequently, reshaped residents’ travel behaviour patterns. As a new mode of shared mobility, the sharing bicycle offers a variety of options for the daily travel of urban residents. Extant studies have mainly examined the travel characteristics and influencing factors of public bicycles with piles, while the travel patterns for sharing bicycles and their driving mechanisms have been largely ignored. Using one week’s travel data for Mobike, this study investigated the spatial and temporal distribution patterns of sharing bicycle travel behaviours in the central urban area of Guangzhou, China;furthermore, it identified the influences of built environment density factors on sharing bicycle travel behaviours based on the geographically weighted regression method. Obvious morning and evening peaks were observed in the sharing bicycle travel patterns for both weekdays and weekends. The old urban area, which had a high degree of mixed function, dense road networks, and cycling-friendly built environments, was the main travel area that attracted sharing bicycles on both weekdays and weekends. Furthermore, factors including the point of interest(POI) for the density of public transport stations, the functional mixing degree, and the density of residential POIs significantly affected residents’ travel behaviours. These findings could enrich discourse regarding shared mobility with a Chinese case characterised by rapidly developing MICTs and also provide references to local authorities for improving slow traffic environments.WEI Zongcai ZHEN Feng MO Haitong WEI Shuqing PENG Danli ZHANG Yuling 2021Chinese Geographical Science2021,31,1:5
4The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs.Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou 2023Horticulture Research2023,10,5:3
5Verifiable Diversity Ranking Search Over Encrypted Outsourced Data显示文摘Data outsourcing has become an important application of cloud computing.Driven by the growing security demands of data outsourcing applications,sensitive data have to be encrypted before outsourcing.Therefore,how to properly encrypt data in a way that the encrypted and remotely stored data can still be queried has become a challenging issue.Searchable encryption scheme is proposed to allow users to search over encrypted data.However,most searchable encryption schemes do not consider search result diversification,resulting in information redundancy.In this paper,a verifiable diversity ranking search scheme over encrypted outsourced data is proposed while preserving privacy in cloud computing,which also supports search results verification.The goal is that the ranked documents concerning diversification instead of reading relevant documents that only deliver redundant information.Extensive experiments on real-world dataset validate our analysis and show that our proposed solution is effective for the diversification of documents and verification.Yuling Liu Hua Peng Jie Wang 2018Computers, Materials & Continua2018,,4:2
6pH-responsive permeability of PE-g-PMAA membranes显示文摘Peng Tao Cheng Yuling 2000Journal of Applied Polymer Science2000,76,6:1
7Using a global reference sample set and a cropland map for area estimation in China显示文摘A technically transparent and freely available reference sample set for validation of global land cover mapping was recently established to assess the accuracies of land cover maps with multiple resolutions.This sample set can be used to estimate areas because of its equal-area hexagon-based sampling design.The capabilities of these sample set-based area estimates for cropland were investigated in this paper.A 30-m cropland map for China was consolidated using three thematic maps(cropland,forest and wetland maps)to reduce confusion between cropland and forest/wetland.We compared three area estimation methods using the sample set and the 30 m cropland map.The methods investigated were:(1)pixel counting from a complete coverage map,(2)direct estimation from reference samples,and(3)model-assisted estimation combining the map with samples.Our results indicated that all three methods produced generally consistent estimates which agreed with cropland area measured from an independent national land use dataset.Areas estimated from the reference sample set were less biased by comparing with a National Land Use Dataset of China(NLUD-C).This study indicates that the reference sample set can be used as an alternative source to estimate areas over large regions.YULe LI XueCao LI CongCong ZHAO YuanYuan NIU ZhenGuo HUANG HuaBing WANG Jie CHENG YuQi LU Hui SI YaLi YU ChaoQing FU HaoHuan GONG Peng 2017Science China Earth Sciences2017,60,2:1
8pH-responsive permeability of PE-g-PMAA membranes显示文摘Peng tao Cheng Yuling 2000J Appl Polym Sci2000,76,9:1
9Dimensions estimation for cone-cylinder target based on sliding-type scatterers analysis显示文摘Scatterers often exhibit aspect or frequency dependence which affects the micro-Doppler shift in scattering response.For cone-cylinder targets, sliding-type scatterers which slide on the edge discontinuity with the change of the incident angle are the most dominant nonideal scattering models. A method is proposed to discriminate among the scatterers on the cone-cylinder target based on the deviation degree of micro-Doppler from sinusoid.By extracting the amplitude and initial phase, the micro-Doppler is estimated as sinusoid. Then the deviation degree is evaluated by the error between the extracted sinusoidal micro-Doppler and the actual micro-Doppler curve. Threshold for the classification is determined with the simulation data. After classification, the micro-Doppler features of sliding-type scatterers are exploited to estimate the target dimensions. The influence of parameters errors and noise on estimation of target dimensions is also illustrated with the simulation data.Yuling Liu Xizhang Wei Bo Peng Yongshun Ling 2017Journal of Systems Engineering and Electronics2017,28,1:1
10High temperature and highly selective stationary phases of ionic liquid bonded polysiloxanes for gas chromatography显示文摘Xiaojie Sun Yuling Zhu Peng Wang Jing Li Caiying Wu Jun Xing 2010Journal of Chromatography A2010,,:1
11Increase in root density induced by coronatine improves maize drought resistance in North China显示文摘Drought stress caused by insufficient irrigation or precipitation impairs agricultural production worldwide.In this study,a two-year field experiment was conducted to investigate the effect of coronatine(COR),a functional analog of jasmonic acid(JA),on maize drought resistance.The experiment included two water treatments(rainfed and irrigation),four COR concentrations(mock,0μmol L^(-1);A1,0.1μmol L^(-1);A2,1μmol L^(-1);A3,10μmol L^(-1))and two maize genotypes(Fumin 985(FM985),a drought-resistant cultivar and Xianyu 335(XY335),a drought-sensitive cultivar).Spraying 1μmol L^(-1)COR at seedling stage increased surface root density and size,including root dry matter by 12.6%,projected root area by 19.0%,average root density by 51.9%,and thus root bleeding sap by 28.2%under drought conditions.COR application also increased leaf area and SPAD values,a result attributed to improvement of the root system and increases in abscisic acid(ABA),JA,and salicylic acid(SA)contents.The improvement of leaves and roots laid the foundation for increasing plant height and dry matter accumulation.COR application reduced anthesis and silking interval,increasing kernel number per ear.COR treatment at 1μmol L^(-1)increased the yield of XY335 and FM985 by 7.9%and 11.0%,respectively.Correlation and path analysis showed that grain yields were correlated with root dry weight and projected root area,increasing maize drought resistance mainly via leaf area index and dry matter accumulation.Overall,COR increased maize drought resistance mainly by increasing root dry weight and root area,with 1μmol L-^(-1)COR as an optimal concentration.Yuling Guo Guanmin Huang Qing Guo Chuanxi Peng Yingru Liu Mingcai Zhang Zhaohu Li Yuyi Zhou Liusheng Duan 2023The Crop Journal2023,11,1:1
12Synthesis, characterization and high-efficiency blue electroluminescence based on coumarin derivatives of 7-diethylamino-coumarin-3- carboxamide显示文摘Yu Tianzhi Zhang Peng Zhao Yuling 2009Org Electron2009,10,4:1
13Common genetic heterogeneity of human interleukin-37 leads to functional variance显示文摘Interleukin-37(IL-37)is an inhibitory member of the IL-1 family of cytokines.We previously found that balanced selection maintains common variations of the human IL37 gene.However,the functional consequences of this selection have yet to be validated.Here,using cells expressing exogenous IL-37 variants,including IL-37 Ref and IL-37 Var1 and Var2,we found that the three variants of IL-37 exhibited different immunoregulatory potencies in response to immune stimulation.The protein level of IL-37 Var2 was found to be significantly less than that of IL-37 Ref or Var1,despite the comparable mRNA levels of all three variants.Further study showed that IL-37 Var2 was rapidly degraded by a proteasome-dependent mechanism mediated by enhanced polyubiquitination,leading to a transient upregulation of IL-37 Var2 after immune stimulation.Finally,when ectopically expressed in cells,human IL-37 Var2 exerted less inhibition on proinflammatory cytokine production than did other IL-37 variants.Conversely,purified extracellular IL-37 variant proteins demonstrated comparable inhibitory abilities in vitro.In conclusion,our study reveals that common genetic variants of IL37 lead to different immune-inhibitory potencies,primarily as a result of differences in IL-37 protein stability,suggesting the possible involvement of these variants in various human diseases.Jingjing Yan Yuling Zhang Shimeng Cheng Bin Kang Jinbiao Peng Xiaodan Zhang Meichun Yuan Wenqi Chu Wen Zhang Jiayin Shen Shuye Zhang 2017Cellular & Molecular Immunology2017,14,9:1
14Characterization of maize leaf pyruvate orthophosphate dikinase using high throughput sequencing显示文摘In C_4 photosynthesis, pyruvate orthophosphate dikinase(PPDK) catalyzes the regeneration of phosphoenolpyruvate in the carbon shuttle pathway. Although the biochemical function of PPDK in maize is well characterized,a genetic analysis of PPDK has not been reported. In this study, we use the maize transposable elements Mutator and Ds to generate multiple mutant alleles of PPDK. Loss-offunction mutants are seedling lethal, even when plants were grown under 2% CO_2, and they show very low capacity for CO_2 assimilation, indicating C_4 photosynthesis is essential in maize. Using RNA-seq and GC-MS technologies, we examined the transcriptional and metabolic responses to a deficiency in PPDK activity. These results indicate loss of sPPDK results in downregulation of gene expression of enzymes of the C_4 cycle, the Calvin cycle, and components of photochemistry. Furthermore, the loss of PPDK did not change Kranz anatomy, indicating that this metabolic defect in the C_4 cycle did not impinge on the morphological differentiation of C_4 characters. However, sugar metabolism and nitrogen utilization were altered in the mutants. An interaction between light intensity and genotype was also detected from transcriptome profiling, suggesting altered transcriptional and metabolic responses to environmental and endogenous signals in the PPDK mutants.Yuling Zhang Rita Giuliani Youjun Zhang Yang Zhang Wagner Luiz Araujo Baichen Wang Peng Liu Qi Sun Asaph Cousins Gerald Edwards Alisdair Fernie Thomas P. Brutnell Pinghua Li 2018Journal of Integrative Plant Biology2018,60,8:1
15Recent progress and future perspectives of flexible metal‐air batteries显示文摘With the rapid development of wearable and intelligent flexible electronic devices(FEDs),the demand for flexible energy storage/conversion devices(ESCDs)has also increased.Rechargeable flexible metal‐air batteries(MABs)are expected to be one of the most ideal ESCDs due to their high theoretical energy density,cost advantage,and strong deformation adaptability.With the improvement of the device design,material assemblies,and manufacturing technology,the research on the electrochemical performance of flexible MABs has made significant progress.However,achieving the high mechanical flexibility,high safety,and wearable comfortability required by FEDs while maintaining the high performance of flexible MABs are still a daunting challenge.In this review,flexible Zn‐air and Li‐air batteries are mainly exemplified to describe the most recent progress and challenges of flexible MABs.We start with an overview of the structure and configuration of the flexible MABs and discuss their impact on battery performance and function.Then it focuses on the research progress of flexible metal anodes,gel polymer electrolytes,and air cathodes.Finally,the main challenges and future research perspectives involving flexible MABs for FEDs are proposed.Tingzhen Li Xinwen Peng Peng Cui Ge Shi Wu Yang Zehong Chen Yongfa Huang Yongkang Chen Jinyuan Peng Ren Zou Xiaoyan Zeng Jian Yu Jianyun Gan Zhiyuan Mu Yuling Chen Jiaming Zeng Juan Liu Yunyi Yang Yujia Wei Jun Lu 2021SmartMat2021,2,4:1
16The commensal consortium of the gut microbiome is associated with favorable responses to anti-programmed death protein 1 (PD-1) therapy in thoracic neoplasms显示文摘Objective:Immune checkpoint inhibitors have revolutionized cancer therapy for multiple types of solid tumors,but as expected,a large percentage of patients do not show durable responses.Biomarkers that can predict clinical responses to immunotherapies at diagnosis are therefore urgently needed.Herein,we determined the associations between baseline gut commensal microbes and the clinical treatment efficiencies of patients with thoracic neoplasms during anti-programmed death protein 1(PD-1)therapy.Methods:Forty-two patients with advanced thoracic carcinoma who received anti-PD-1 treatment were enrolled in the study.Baseline and time-serial stool samples were analyzed using 16S ribosomal RNA gene sequencing.Tumor responses,patient progression-free survival,and overall survival were used to measure clinical outcomes.Results:The diversities of the baseline gut microbiota were similar between responders(n=23)and nonresponders(n=19).The relative abundances of the Akkermansiaceae,Enterococcaceae,Enterobacteriaceae,Carnobacteriaceae and Clostridiales Family XI bacterial families were significantly higher in the responder group.These 5 bacterial families acted as a commensal consortium and better stratified patients according to clinical responses(P=0.014).Patients with a higher abundance of commensal microbes had prolonged PFS(P=0.00016).Using multivariable analysis,the abundance of the commensal consortium was identified as an independent predictor of anti-PD-1 immunotherapy in thoracic neoplasms(hazard ratio:0.17;95%confidence interval:0.05–0.55;P=0.003).Conclusions:Baseline gut microbiota may have a critical impact on anti-PD-1 treatment in thoracic neoplasms.The abundance of gut commensal microbes at diagnosis might be useful for the early prediction of anti-PD-1 immunotherapy responses.Huihui Yin Lu Yang Gongxin Peng Ke Yang Yuling Mi Xingsheng Hu Xuezhi Hao Yuchen Jiao Xiaobing Wang Yan Wang 2021Cancer Biology & Medicine2021,18,4:0
17AFLP and MSAP Analysis of ‘Lane Late’ Navel Orange and Its Bud Sport Pumpkin-like Navel Orange显示文摘[Objectives]The paper was to analyze the differences of genes and genome methylation between‘lane late’navel orange and it’s bud sport pumpkin-like navel orange,and to reveal the causes of bud sport.[Methods]Amplification fragment length polymorphism(AFLP)and methylation sensitive amplification polymorphism(MSAP)were used to analyze the differences in genes and genome methylation of‘lane late’navel orange and its bud sport pumpkin-like navel orange.[Results]Gene mutation occurred between the‘lane late’navel orange and its bud sport pumpkin-like navel orange.A total of 15 differential bands were obtained by AFLP markers,and the percentage of polymorphic bands was 6.0000%.Meantime,10 differential bands were obtained by MSAP markers,and the percentage of polymorphic bands was 5.4645%.The semimethylation rate and permethylation rate of‘lane late’navel orange were higher than that of pumpkin-like navel orange,that is,pumpkin-like navel orange had demethylation(demethylation ratio was 1.6393%).[Conclusions]It is proved at the DNA level that the emergence of bud sport pumpkin-like navel orange is due to gene mutation,and the DNA methylation level of the bud sport material has also changed.This study lays a foundation for further exploring the mechanism of bud sport.Chunwang LAI Yuling LIN Xiaojuan ZHOU Ting PENG 2022Plant Diseases and Pests2022,13,1:0
18Library's industrial technology information service in science parks—Taking NSL's practice as an example显示文摘Purpose:The purpose of this paper is to explore how libraries can develop service and product strategies and the service support mechanism to provide industrial technology information service in science parks.Design/methodology/approach:The analysis is based on a case study of a large Chinese research library,National Science Library(NSL),the Chinese Academy of Sciences(CAS),in serving high-tech companies in Zhongguancun Science Park(Z-Park).Findings:NSL's practices suggested that in serving business clients,libraries' product and service strategies should be based on the understanding of users' needs.Aside from those services that have been recognized by clients such as document retrieval & delivery and novelty search,libraries may expand their service and provide in-depth information analysis and consultation for some key clients.Moreover,a service and product development system should be established,which differentiates the libraries' products and services from those of their competitors.In providing industrial technology information service,libraries need to construct the service support mechanism,publicize their service and learn to cooperate with clients to meet their demands for knowledge management and innovation.Research limitations:The generalizability of the findings is limited because they are based on an individual case study.Practical implications:Our service practices provide useful information for other libraries to expand their information service to high-tech companies in the new information environment.Originality/value:Z-Park is the first and one of the largest science and technology parks in China.Hence NSL's practices in serving high-tech companies in Z-Park can be valuable to other libraries that intend to take up the similar service.Fei ZHENG Hao PENG Fang CHEN Hualing XIE Yuling SUN 2014Chinese Journal of Library and Information Science2014,,1:0
19Weakened humoral immune responses of inactivated SARS-CoV-2 vaccines in patients with solid tumors显示文摘Dear Editor Coronavirus disease 19(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),remains a pandemic.Cancer patients have a higher risk of poor outcomes for SARS-CoV-2 infection than the general population[1].Vaccines were shown to effectively prevent SARS-CoV-2 infection,severe disease progression,and mortality.Inactivated SARS-CoV-2 vaccines(BBIBPCorV and CoronaVac)have been approved and widely used in China,with the former shown to be more effective than the latter[2].Hence,there is an urgent need to investigate the safety and humoral immune responses of inactivated vaccines in cancer patients.Zhiwei Chen Peng Zhu Zuojin Liu Bin Zhu Guobing Yin Jia Ming Rui Song Qingbo Pan Tong Li Xingwei Jiang Bing Wang Shuaibin Liu Hongxing Cai Jingjie Wang Yuling Han Zijing Lin Yang Hong Min Chen Mingli Peng Lina Hu Dachuan Cai Hong Ren 2023Cancer Communications2023,43,2:0
20Identification of binding domains and key amino acids involved in the interaction between BmLARK and G4 structure in the BmPOUM2 promoter in Bombyx mori显示文摘It has been found that the non-B form DNA structures,like G-quadruplex(G4)and i-motif,are involved in many important biological processes.Our previous study showed that the silkworm transcription factor BmLARK binds to the G4 structure in the promoter of the transcription factor BmPOUM2 and regulates its promoter activity.However,the binding mechanism between BmLARK and BmPOUM2 G4 structure remains unclear.In this study,binding domains and key amino acid residues involved in the interaction between BmLARK and BmPOUM2 G4 were studied.The electrophoretic mobility shift assay results indicated that the two RNA-recognition motifs(RRM)of BmLARK are simultaneously required for the binding with the G4 structure.Either RRM1 or RRM2 alone could not bind with the G4 structure.The zinc-finger motif was not involved in the binding.A series of mutant proteins with specific amino acid mutations were expressed and used to identify the key amino acid residues involving the interaction.The results indicated thatβsheets,especially theβ1 andβ3 sheets,in the RRM domains of BmLARK played critical roles in the binding with the G4 structure.Several amino acid mutations of RRM1/2 in ribonucleoprotein domain 1(RNP1)(motif inβ3 strand)and RNP2(motif inβ1 strand)caused loss of binding ability,indicating that these amino acids are the key sites for the binding.All the results suggest that RRM domains,particularly their the RNP1 and RNP2 motifs,play important roles not only in RNA recognition,but also in the G4 structure binding.Yuling Peng Kangkang Niu Guoxing Yu Mingxi Zheng Qiulan Wei Qisheng Song Qili Feng 2021Insect Science2021,28,4:0
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