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| 1 | The role played by traditional Chinese medicine in preventing and treating COVID-19 in China显示文摘Traditional Chinese medicine(TCM),an ancient system of alternative medicine,played an active role in the prevention and control of COVID-19 in China.It improved the clinical symptoms of patients,reduced the mortality rate,improved the recovery rate,and effectively relieved the operating pressure on the national medical system during critical conditions.In light of the current global pandemic,TCM-related measures might open up a new channel in the control of COVID-19 in other countries and regions.Here,we summarize the TCM-related measures that were widely used in China,including TCM guidelines,the Wuchang pattern,mobile cabin hospitals,integrated treatment of TCM and modern medicine for critical patients,and non-medicine therapy for convalescent patients,and describe how TCM effectively treated patients afflicted with the COVID-19.Effective TCM therapies could,therefore,be recommended and practiced based on the existing medical evidence from increased scientific studies. | Qingwei Li Han Wang Xiuyang Li Yujiao Zheng Yu Wei Pei Zhang Qiyou Ding Jiaran Lin Shuang Tang Yikun Zhao Linhua Zhao Xiaolin Tong | 2020 | Frontiers of Medicine2020，14，5： | 10 |
| 2 | Metal chalcogenide complex-mediated fabrication of Cu_2S film as counter electrode in quantum dot sensitized solar cells显示文摘Cu2S film onto FTO glass substrate was obtained to function as counter electrode for polysulfide redox reactions in CdS/CdSe co-sensitized solar cells by sintering after spraying a metal chalcogenide complex, N4H9Cu7S4 solution. Relative to Pt counter electrode, the Cu2S counter electrode provides greater electrocatalytic activity and lower charge transfer resistance. The prepared Cu2S counter electrode represented nanoflower-like porous film which was composed of Cu2S nanosheets on FTO and had a higher surface area and lower sheet resistance than that of sulfided brass Cu2S counter electrode. An energy conversion efficiency of 3.62% was achieved using the metal chalcogenide complex-mediated fabricated Cu2S counter electrode for CdS/CdSe co-sensitized solar cells under 1 sun, AM 1.5 illumination. | YU XueChao ZHU Jun LIU Feng WEI JunFeng HU LinHua DAI SongYuan | 2013 | Science China Chemistry2013，56，7： | 6 |
| 3 | Interpretation of the Traditional Chinese Medicine portion of the diagnosis and treatment protocol for corona virus disease 2019(Trial Version 7)显示文摘The TCM protocol in the Diagnosis and Treatment Protocol for corona virus disease 2019(COVID-19)(Trial Version 7) has been updated from previous versions. The protocol was formulated under the direct leadership of the National Administration of Traditional Chinese Medicine, based on the experience of a panel of experts, supported by evidence from fever clinics and from the outcomes of emergency(EM) observation rooms and inpatients throughout China(especially in Wuhan, Hubei Province) in combination with the latest scientific research results and data. The present interpretation of the TCM protocol is based on an overall understanding of the revised content, and aims to guide and standardize its clinical application to provide a reference for clinicians. | Song Ping Zhao Linhua Li Xiuyang Su Jiansen Jiang Zhaoyuan Song Bin Liu Wenke Tang Shuang Lei Ye Ding Qiyou Yang Ze Lin Jiaran Wei Yu Tong Xiaolin | 2020 | Journal of Traditional Chinese Medicine2020，40，3： | 5 |
| 4 | Chinese expert consensus on the management of chimeric antigen receptor T cell therapy-associated coagulopathy显示文摘Chimeric antigen receptor T-cell(CAR-T)therapy has greatly improved the disease remission rate and long-term survival rate of patients with relapsed/refractory hematological malignancies.[1-3]Currently,several commercial CAR-T products are available in the market and numerous CAR-T clinical trials have been conducted.Attention should be paid to the safety of CAR-T therapy.The main adverse effects of CAR-T therapy are cytokine release syndrome(CRS)and immune effector cell-associated neurotoxicity syndrome(ICANS).[4] | Heng Mei Fangping Chen Yue Han Ming Hou He Huang Xiaojun Huang Yuhua Li Aibin Liang Qifa Liu Ting Niu Jun Peng Wenbin Qian Yongping Song Jianxiang Wang Ying Wang Depei Wu Kailin Xu Linhua Yang Renchi Yang Lei Zhang Liansheng Zhang Xi Zhang Xiaohui Zhang Weili Zhao Weidong Han Yu Hu | 2022 | Chinese Medical Journal2022，，14： | 4 |
| 5 | Analysis of microclimate characteristics in solar greenhouses under natural ventilation显示文摘The solar greenhouse is a typical greenhouse type in northern China.It provides a favorable environment for the growth of various plants and extends cultivation periods for almost a whole year to achieve a high yield.However,indoor environmental control is primarily based on growers'experience,and the objective test data required for the complex climate control and management of greenhouses are lacking.The present study used three greenhouses in northwest China as research objects:one greenhouse with mature plants(GH-M),one greenhouse with young plants(GH-Y)and one greenhouse without plants(GH-E).Field tests were performed to investigate microclimate characteristics,such as indoor air temperature,relative humidity,and solar radiation under natural ventilation.The results showed that the maximum temperature difference reached approximately 8.2℃in the vertical direction,and semiempirical equations for the normalized temperature distribution were obtained.The soil temperature remained constant at a certain depth(0.4 m).The distribution of the relative humidity and solar radiation was analyzed.The current study is helpful for growers to develop better greenhouse climate control strategies for management practices. | Yicun Hou Angui Li Yue Li Dacheng Jin Yu Tian Da Zhang Dingmeng Wu Linhua Zhang Wenjun Lei | 2021 | Building Simulation2021，14，6： | 3 |
| 6 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5h50pquqf06uub6vo6.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 7 | Theoretical investigation of electronic structure, elastic and thermodynamic properties of chalcopyrite CdSiP 2显示文摘 | Zhiyu He Beijun Zhao Shifu Zhu Baojun Chen Haijun Hou You Yu Linhua Xie | 2013 | Computational Materials Science2013，，： | 1 |
| 8 | Temperature Distributions in an Absorbing-Emitting-Scattering Semi- transparent Slab With Variable Spatial Refractive Index 显示文摘 | LIU Linhua TAN Heping YU Qizheng | 2003 | International Journal of Heat and Mass Transfer2003，46，： | 1 |
| 9 | Podocyte injury and overexpression of vascular endothelial growth factor and transforming growth factor-beta 1 in adriamycin-induced nephropathy in rats显示文摘 | Weina Yang Junjian Wang Lili Shi Linhua Yu Yihua Qian Yong Liu Weixi Wang Shaoli Cheng | 2012 | Cytokine2012，，2： | 1 |
| 10 | LHRH/TAT dual peptides-conjugated polymeric vesicles for PTT enhanced chemotherapy to overcome hepatocellular carcinoma显示文摘Combination therapy such as photothermal therapy(PTT)enhanced chemotherapy is regarded as a promising strategy for cancer treatment.Herein,we developed redox-responsive polymeric vesicles based on the amphiphilic triblock copolymer PCL-ss-PEG-ss-PCL.To avoid the limited therapeutic effect of chemotherapeutic drugs caused by systemic exposures and drug resistance,the redox-sensitive polymeric vesicles were cargoed with two chemotherapeutics:doxorubicin(DOX)and paclitaxel(PTX).Besides,indocyanine green(ICG)was encapsulated,and cell-penetrating peptides and LHRH targeting molecule were modified on the surface of polymeric vesicles.The results indicated that the polymeric vesicles can load different kinds of drugs with high drug loading content,trigger drug release in responsive to the reductive environment,realize high cellular uptake via dual peptides and laser irradiation,and achieve higher cytotoxicity via chemo-photothermal combination therapy.Hence,the redox-responsive LHRH/TAT dual peptides-conjugated PTX/DOX/ICG co-loaded polymeric micelles exhibited great potential in tumor-targeting and chemo-photothermal therapy. | Yu Qin Qing Guo Shengjie Wu Chenlu Huang Zhiming Zhang Li Zhang Linhua Zhang Dunwan Zhu | 2020 | Chinese Chemical Letters2020，31，12： | 1 |
| 11 | Detection and significance of HBV in renal tissue of HBV associated glomerulonephrifis patients 显示文摘 | Ren Shuting Yu Linhua Xu Changfu | 2002 | ACAD J XJTU2002，14，2： | 1 |
| 12 | An efficient preparation of porous polymeric microspheres by solvent evaporation in foam phase显示文摘This paper reports an efficient method of preparing porous polymeric microspheres by solvent evaporation in foam phase,in which phase separation between polymer and porogen occurs in foam phase instead of that in water phase by using the traditional solvent eva poration method.The method provides outstanding features,including being time-saving,of high-yield and able for continuous production,in which formation of porous polymeric microspheres finished within 3 min with a high production yield up to approximate 95 wt% and the process was able to be developed into a continuous process for production of porous polymeric microspheres.It was also universal to non-crosslinked polymers since the method is a development on the traditional emulsion solvent evaporation method.The new method is efficient and can be used potentially on the industrial scale for continuous production of porous polymeric microsphere s. | Yang Yu Guiying Li Wanqing Han Linhua Zhu Tian Si HongWang Yanlin Sun Yanping He | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 1 |
| 13 | Flexural per- formance of concrete beams reinforced by hybrid FRP 显示文摘 | Yu Lin Jiang Linhua Chu Hungkeung | 2006 | Building Materials2006，，3： | 1 |
| 14 | Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19显示文摘Traditional Chinese medicine(TCM)has played an important role in the prevention and treatment of Coronavirus disease 2019(COVID-19)epidemic in China.The integration of Chinese and Western medicine is an important feature of Chinese COVID-19 prevention and treatment.According to a series of evidence-based studies,TCM can reduce the infection rate of severe acute respiratory syndrome coronavirus 2 in high-risk groups.For patients with mild and moderate forms of COVID-19,TCM can relieve the related signs and symptoms,shorten the period of nucleic-acid negative conversion,and reduce conversion rate to the severe form of the disease.For COVID-19 patients with severe and critical illnesses,TCM can improve inflammatory indicators and blood oxygen saturation,shorten the hospital stay,and reduce the mortality rate.During recovery,TCM can improve patients’symptoms,promote organ function recovery,boost the quality of patients’life,and reduce the nucleic-acid repositive conversion rate.A series of mechanism research studies revealed that capability of TCM to treat COVID-19 through antiviral and anti-inflammatory effects,immune regulation,and protection of organ function via a multicomponent,multitarget,and multipathway approach. | Linhua Zhao Chuanxi Tian Yingying Yang Huifang Guan Yu Wei Yuxin Zhang Xiaomin Kang Ling Zhou Qingwei Li Jing Ma Li Wan Yujiao Zheng Xiaolin Tong | 2023 | Frontiers of Medicine2023，17，6： | 0 |
| 15 | Microbiome and metabolome dysbiosis analysis in impaired glucose tolerance for the prediction of progression to diabetes mellitus显示文摘Gut microbiota and circulating metabolite dysbiosis predate important pathological changes in glucose metabolic disorders;however,comprehensive studies on impaired glucose tolerance(IGT),a diabetes mellitus(DM)precursor,are lacking.Here,we perform metagenomic sequencing and metabolomics on 47 pairs of individuals with IGT and newly diagnosed DM and 46 controls with normal glucose tolerance(NGT);patients with IGT are followed up after 4 years for progression to DM.Analysis of baseline data reveals significant differences in gut microbiota and serum metabolites among the IGT,DM,and NGT groups.In addition,13 types of gut microbiota and 17 types of circulating metabolites showed significant differences at baseline before IGT progressed to DM,including higher levels of Eggerthella unclassified,Coprobacillus unclassified,Clostridium ramosum,L-valine,L-norleucine,and L-isoleucine,and lower levels of Eubacterium eligens,Bacteroides faecis,Lachnospiraceae bacterium 3_1_46FAA,Alistipes senegalensis,Megaspaera elsdenii,Clostridium perfringens,α-linolenic acid,10E,12Z-octadecadienoic acid,and dodecanoic acid.A random forest model based on differential intestinal microbiota and circulating metabolites can predict the progression from IGT to DM(AUC=0.87).These results suggest that microbiome and metabolome dysbiosis occur in individuals with IGT and have important predictive values and potential for intervention in preventing IGT from progressing to DM. | Boxun Zhang Xuan Zhang Zhen Luo Jixiang Ren Xiaotong Yu Haiyan Zhao Yitian Wang Wenhui Zhang Weiwei Tian Xiuxiu Wei Qiyou Ding Haoyu Yang Zishan Jin Xiaolin Tong Jun Wang Linhua Zhao | 2024 | Journal of Genetics and Genomics2024，51，1： | 0 |
| 16 | Preparation and Performance of Chitosan/Citric Acid Modified Magnesium Oxychloride Cement显示文摘Citric acid(CA)and chitosan(CS)were employed to modify magnesium oxychloride cement(MOC).Multiscale measurements were implemented to study the properties of the modified MOC pastes.Results show that the addition of CA/CS significantly changes the content of each phase and the microstructure of phase 5.The single addition of CA can effectively increase the compressive strength of MOC after 7 d curing,while CS exerts no obvious effect on the compressive strength.As to the simultaneous addition of CA and CS,the compressive strength of MOC gradually decreases with the increasing content of CS.Interestingly,mixing CA and CS significantly enhances the water resistance of MOC and decreases the degradation rate of MOC in phosphate buffered solution,which can be ascribed to the low specific surface area of the plate-like crystals in the modified MOC and the reduction of pores in the structure. | SONG Zijian LIU Lang YU Peipei ZHANG Yunsheng LI Xincheng CHU Hongqiang JIANG Linhua | 2023 | Journal of Wuhan University of Technology(Materials Science)2023，38，6： | 0 |
| 17 | A prototype of benzobis(imidazolium)-embedded conjugated polyelectrolyte: Synthesis by direct C–H arylation and fluorescent responses to anions显示文摘We report the convenient synthesis of a benzobis(imidazolium)-embedded conjugated polyelectrolyte pBBI by a Cu-catalyzed direct C–H arylation of a cationic benzobis(imidazolium)monomer with a di-iodide comonomer.pBBI shows weak fluorescence in solution due to rotation of the repeat units in the conjugated backbone,and enhanced fluorescence when electrostatically interacting with a variety of an-ions to form aggregates.Specially,pBBI responds to the bisulfite anion with intensified unique deep-blue fluorescence easily discriminated by naked eye. | Chuangui Yu Qinze Zheng Linhua Wang Tianbao Wang Xuesong Zheng Ge Gao | 2022 | Chinese Chemical Letters2022，33，5： | 0 |
| 18 | Distinct gut microbiota and health outcomes in asymptomatic infection,viral nucleic acid test re-positive,and convalescent COVID-19 cases显示文摘Gut microbiota composition is suggested to associate with coronavirus disease 2019(COVID-19)severity,but the impact of gut microbiota on health outcomes is largely unclear.We recruited 81 individuals from Wuhan,China,including 13 asymptomatic infection cases(Group A),24 COVID-19 convalescents with adverse outcomes(Group C),31 severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)re-positive cases(Group D),and 13 non-COVID-19 healthy controls(Group H).The microbial features of Groups A and D were similar and exhibited higher gut microbial diversity and more abundant short-chain fatty acid(SCFA)-producing species than Group C.Group C was enriched with opportunistic pathogens and virulence factors related to adhesion and toxin production.The abundance of SCFA-producing species was negatively correlated,while Escherichia coli was positively correlated with adverse outcomes.All three groups(A,C,and D)were enriched with the mucusdegrading species Akkermansia muciniphila,but decreased with Bacteroides-encoded carbohydrate-active enzymes.The pathways of vitamin B6 metabolic and folate biosynthesis were decreased,while selenocompound metabolism was increased in the three groups.Specifically,the secondary bile acid(BA)metabolic pathway was enriched in Group A.Antibiotic resistance genes were common among the three groups.Conclusively,the gut microbiota was related to the health outcomes of COVID-19.Dietary supplementations(SCFAs,BA,selenium,folate,vitamin B6)may be beneficial to COVID-19 patients. | Ruqin Lin Mingzhong Xiao Shanshan Cao Yu Sun Linhua Zhao Xiaoxiao Mao Peng Chen Xiaolin Tong Zheyuan Ou Hui Zhu Dong Men Xiaodong Li Yiqun Deng Xian-En Zhang Jikai Wen | 2022 | mLife2022，1，2： | 0 |
| 19 | Observations of the solar corona during the total solar eclipse on 21 August 2017显示文摘The Sun’s tenuous outer atmosphere,the corona,emits only about one-millionth as much light as the solar surface.In ancient times the corona was observed by human beings only during total solar eclipses,when the strong emission of visible light from the photosphere was completely blocked by the Moon.In 1931, | Hui Tian ZhongQuan Qu YaJie Chen LinHua Deng ZhengHua Huang Hao Li Yue Zhong Yu Liang JingWen Zhang YiGong Zhang BaoLi Lun XiangMing Cheng XiaoLi Yan ZhiKe Xue YuXin Xin ZhiMing Song YingJie Zhu Tanmoy Samanta | 2017 | Earth and Planetary Physics2017，1，1： | 0 |
| 20 | Range resolution and sampling frequency trade-off for GPS passive radar显示文摘In a global positioning system(GPS)passive radar,a high resolution requires a high sampling frequency,which increases the computational load.Balancing the computational load and the range resolution is challenging.This paper presents a method to trade off the range resolution and the computational load by experimentally determining the optimal sampling frequency through an analysis of multiple sets of GPS satellite data at different sampling frequencies.The test data are used to construct a range resolution-sampling frequency trade-off model using least-squares estimation.The theoretical analysis shows that the experimental data are the best fit using smoothing and nthorder derivative splines.Using field GPS C/A code signal-based GPS radar,the trade-off between the optimal sampling frequency is determined to be in the 20461.25–24553.5 kHz range,which supports a resolution of 43–48 m.Compared with the conventional method,the CPU time is reduced by approximately 50%. | ZHANG Zhuxian ZHENG Yu ZHENG Linhua ZHU Peidong | 2022 | Journal of Systems Engineering and Electronics2022，33，1： | 0 |
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