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| 1 | New pyrometallurgical process of EAF dust treatment with CaO addition显示文摘The non-carbothermic zinc pyrometallurgical processing of electric arc furnace(EAF) dust was investigated on a laboratory scale. The main objective of this process was to convert highly stable zinc ferrite(Zn Fe2O4), which accounts for more than half of total zinc in the EAF dust, into Zn O and Ca2Fe2O5 by Ca O addition. The EAF dust was mixed with Ca O powder in various ratios, pressed into pellets, and heated in a muffle furnace in air at temperatures ranging from 700 to 1100°C for a predetermined holding time. All Zn Fe2O4 was transformed into Zn O and Ca2Fe2O5 at a minimum temperature of 900°C within 1 h when sufficient Ca O to achieve a Ca/Fe molar ratio of 1.1 was added. However, at higher temperatures, excess Ca O beyond the stoichiometric ratio was required because it was consumed by reactions leading to the formation of compounds other than Zn Fe2O4. The evaporation of halides and heavy metals in the EAF dust was also studied. These components could be preferentially volatilized into the gas phase at 1100°C when Ca O was added. | Romchat Chairaksa-Fujimoto Yosuke Inoue Naoyoshi Umeda Satoshi Itoh Tetsuya Nagasaka | 2015 | International Journal of Minerals,Metallurgy and Materials2015，22，8： | 7 |
| 2 | Neither Multiple Tumors Nor Portal Hypertension Are Surgical Contraindications for Hepatocellular Carcinoma显示文摘 | Takeaki Ishizawa Kiyoshi Hasegawa Taku Aoki Michiro Takahashi Yosuke Inoue Keiji Sano Hiroshi Imamura Yasuhiko Sugawara Norihiro Kokudo Masatoshi Makuuchi | 2008 | Gastroenterology2008，，7： | 7 |
| 3 | Influence of cognitive impairment on cardiac mortality after percutaneous coronary intervention in very elderly patients: a retrospective observational study显示文摘Background Cognitive impairment (CI) increases cardiac mortality among very elderly patients. Percutaneous coronary intervention (PCI) for ischemic heart disease (IHD) patients is considered a favorable strategy for decreasing cardiac mortality. Here, we investigated the influence of CI on cardiac mortality after PCI in very elderly patients. Methods We performed a retrospective observational analysis of patients who received PCI between 2012 and 2014 at the South Miyagi Medical Center, Japan. IHD patients over 80 years old who underwent the Mini-Mental State Examination for CI screening during hospitalization and/or who had been diagnosed with CI were included. Participants were divided into CI and non-CI groups, and cardiac mortality and incidence of adverse cardiac events in a 3-year follow-up period were compared between groups. Statistical analyses were performed using the t-test,χ^2 test, and multivariable Cox regression analysis, with major comorbid illness and conventional cardiac risk factors as confounders. Results Of 565 patients, 95 were included (41 CI, 54 non-CI). Cardiac mortality during the follow-up period was significantly higher in the CI group (36%) compared with the non-CI group (13%)(OR = 4.3, 95% CI: 1.56–11.82, P < 0.05). CI was an independent cardiac prognostic factor after PCI and, for CI patients, living only with a CI partner was an independent predictor of cardiac death within three years. Conclusions CI significantly affected cardiac prognosis after PCI in very elderly patients, particularly those living with a CI partner. To improve patients’ prognoses, social background should be considered alongside conventional medical measures. | Tomoko Tomioka Ryokichi Takahashi Yosuke Ikumi Shuhei Tanaka Yoshitaka Ito Hiroki Shioiri Jiro Koyama Kanichi Inoue | 2019 | Journal of Geriatric Cardiology2019，16，10： | 3 |
| 4 | Effects of oral tacrolimus as a rapid induction therapy in ulcerative colitis显示文摘AIM:To determine the efficacy and safety of rapid induction therapy with oral tacrolimus without a meal in steroid-refractory ulcerative colitis(UC)patients.METHODS:This was a prospective,multicenter,observational study.Between May 2010 and August 2012,49 steroid-refractory UC patients(55 flare-ups)were consecutively enrolled.All patients were treated with oral tacrolimus without a meal at an initial dose of 0.1mg/kg per day.The dose was adjusted to maintain trough whole-blood levels of 10-15 ng/m L for the first 2 wk.Induction of remission at 2 and 4 wk after tacrolimus treatment initiation was evaluated using Lichtiger’s clinical activity index(CAI).RESULTS:The mean CAI was 12.6±3.6 at onset.Within the first 7 d,93.5%of patients maintained high trough levels(10-15 ng/m L).The CAI significantly decreased beginning 2 d after treatment initiation.At 2wk,73.1%of patients experienced clinical responses.After tacrolimus initiation,31.4%and 75.6%of patients achieved clinical remission at 2 and 4 wk,respectively.Treatment was well tolerated.CONCLUSION:Rapid induction therapy with oral tacrolimus shortened the time to achievement of appropriate trough levels and demonstrated a high remission rate 28 d after treatment initiation.Rapid induction therapy with oral tacrolimus appears to be a useful therapy for the treatment of refractory UC. | Ken Kawakami Takuya Inoue Mitsuyuki Murano Ken Narabayashi Sadaharu Nouda Kumi Ishida Yosuke Abe Koji Nogami Nobuyuki Hida Hirokazu Yamagami Kenji Watanabe Eiji Umegaki Shiro Nakamura Tetsuo Arakawa Kazuhide Higuchi | 2015 | World Journal of Gastroenterology2015，21，6： | 3 |
| 5 | Applicability of second‐generation colon capsule endoscope to ulcerative colitis: A clinical feasibility study显示文摘 | Naoki Hosoe Katsuyoshi Matsuoka Makoto Naganuma Yosuke Ida Yuka Ishibashi Kayoko Kimura Kazuaki Yoneno Shingo Usui Kazuhiro Kashiwagi Tadakazu Hisamatsu Nagamu Inoue Takanori Kanai Hiroyuki Imaeda Haruhiko Ogata Toshifumi Hibi | 2013 | J Gastroenterol Hepatol2013，，7： | 3 |
| 6 | Overexpression of ETS-1 is associated with malignan' biological features of prostate cancer显示文摘E26 transformation-specific-1 ( ETS-1 ),一个 et 家庭抄写因素,被报导了在前列腺癌症( PCa )在 ETS-1 表示的许多生理、病理学的过程,而是临床的含意起一个重要作用,特别地高风险的案例,包括对雄激素剥夺的反应,治疗( ADT )还得被阐明。我们用针活体检视从 69 个主要先进的 PCa 病人获得的嵌入石蜡的前列腺癌织物染色的 immunohistochemical 检验了 ETS-1 的表示。ETS-1 表示与 69 个病人的 clinicopathological 特征相比,包括 25 作为主要治疗经历了 ADT。作为结果,有 ETS-1 的更高的表示的 PCa 病人是显著地,可能舞台高的更多得分(P< 0.05 ) 。在 ETS-1 表示和起始的前列腺特定的抗原(PSA ) 水平之间没有重要协会。在 ADT 对待的 25 个病人,为 ETS-1 的染色的分数显著地在 24 个月以内与阉割抵抗的疾病的快速的开发被联系(P< 0.05 ) ,而格利森分数和 PSA 水平不是。在结论,增加了 ETS-1 表示与到阉割抵抗的前进的一个更高的阶段,更高级的格利森分数和更短的时间被联系。这些数据建议为 ETS-1 的 immunostaining 能是为为 PCa 病人预言差的临床的结果的一个分子的标记,特别地那些与高风险的疾病。 | Bo Li Yosuke Shimizu Takashi Kobayashi Naoki Terada Koji Yoshimura Tomomi Kamba Yoshiki Mikami Takahiro Inoue Hiroyuki Nishiyama Osamu Ogawa | 2012 | Asian Journal of Andrology2012，14，6： | 2 |
| 7 | Risk factors of post‐operative recurrence and adequate surgical approach to improve long‐term outcomes of hepatocellular carcinoma显示文摘 | Junichi Shindoh Kiyoshi Hasegawa Yosuke Inoue Takeaki Ishizawa Rihito Nagata Taku Aoki Yoshihiro Sakamoto Yasuhiko Sugawara Masatoshi Makuuchi Norihiro Kokudo | 2012 | HPB2012，，1： | 2 |
| 8 | Isolated ileal perforation due to cytomegalovirus reactivation during management of terbinafine hypersensitivity显示文摘We report a case of 71-year-old man who developed a hypersensitivity syndrome associated with terbinafine. He was placed on terbinafine (250 mg/d) for the treatment of tinea pedis due to diabetes mellitus. Following the treatment with terbinafine, he developed druginduced hypersensitivity syndrome (DIHS). Systemic corticosteroid led to transient improvement of his clinical manifestations. Three months after disease onset, he presented with panperitonitis due to ileal perforation, and underwent an emergency operation. The affected ileum was resected and ileostomy was performed in the terminal ileum. Cytomegalovirus (CMV)-specific IgG antibodies were significantly increased, high-titer CMV antigenemia was detected, and pathological examination of the resected ileum confirmed CMV infection. Based onthese observations, we strongly recommend that physicians monitor reactivation of the family of herpesvirus other than herpesvirus 6, to manage DIHS properly. | Soichi Sano Hiroki Ueno Keiko Yamagami Yosuke Yakushiji Yoshihiro Isaka Isao Kawasaki Masashi Takemura Takeshi Inoue Masayuki Hosoi | 2010 | World Journal of Gastroenterology2010，16，26： | 2 |
| 9 | Tranilast Prevents Atrial Remodeling and Development of Atrial Fibrillation in a Canine Model of Atrial Tachycardia and Left Ventricular Dysfunction显示文摘 | Yosuke Nakatani Kunihiro Nishida Masao Sakabe Naoya Kataoka Tamotsu Sakamoto Yoshiaki Yamaguchi Jotaro Iwamoto Koichi Mizumaki Akira Fujiki Hiroshi Inoue | 2013 | Journal of the American College of Cardiology2013，，： | 1 |
| 10 | Usefulness of Contrast-Enhanced Intraoperative Ultrasound in Identifying Disappearing Liver Metastases from Colorectal Carcinoma After Chemotherapy显示文摘 | Junichi Arita Yoshihiro Ono Michiro Takahashi Yosuke Inoue Yu Takahashi Akio Saiura | 2014 | Annals of Surgical Oncology2014，，3： | 1 |
| 11 | Is there any difference in survival according to the portal tumor thrombectomy method in patients with hepatocellular carcinoma?显示文摘 | Yosuke Inoue Kiyoshi Hasegawa Takeaki Ishizawa Taku Aoki Keiji Sano Yoshifumi Beck Hiroshi Imamura Yasuhiko Sugawara Norihiro Kokudo Masatoshi Makuuchi | 2009 | Surgery2009，，1： | 1 |
| 12 | Neither Multiple Tumors Nor Portal Hypertension Are Surgical Contraindications for Hepatocellular Carcinoma显示文摘 | Takeaki Ishizawa Kiyoshi Hasegawa Taku Aoki Michiro Takahashi Yosuke Inoue Keiji Sano Hiroshi Imamura Yasuhiko Sugawara Norihiro Kokudo Masatoshi Makuuchi | 2008 | Gastroenterology2008，，7： | 1 |
| 13 | Intra-operative freehand real-time elastography for small focal liver lesions: “Visual palpation” for non-palpable tumors显示文摘 | Yosuke Inoue Michiro Takahashi Junichi Arita Taku Aoki Kiyoshi Hasegawa Yoshifumi Beck Masatoshi Makuuchi Norihiro Kokudo | 2010 | Surgery2010，，5： | 1 |
| 14 | Lymphatic Microvessel Density is an Independent Prognostic Factor in Colorectal Cancer显示文摘 | Kentaro Matsumoto M.D. Yoshifumi Nakayama M.D. Ph.D. Yuzuru Inoue M.D. Ph.D. Noritaka Minagawa M.D. Ph.D. Takefumi Katsuki M.D. Kazunori Shibao M.D. Ph.D. Yosuke Tsurudome M.D. Ph.D. Keiji Hirata M.D. Ph.D. Naoki Nagata M.D. Ph.D. Hideaki Itoh M.D. | 2007 | Diseases of the Colon & Rectum2007，，3： | 1 |
| 15 | Selective production of organic acids and depolymerization of lignin by hydrothermal oxidation with diluted hydrogen peroxide显示文摘 | ISAO Hasegawa YUSUKE Inoue YOSUKE Muranaka | 2011 | Energy Fuels2011，25，： | 1 |
| 16 | Selective produc- tion of organic acids and depolymerization of lignin by hydro- thermal oxidation with diluted hydrogen peroxide显示文摘 | Hasegawa I Inoue Y Muranaka Yosuke | 2011 | Energy Fuels2011，25，2： | 1 |
| 17 | Japanese apricot improves symptoms of gastrointestinal dysmotility associated with gastroesophageal reflux disease显示文摘AIM: To investigate the effects of Japanese apricot(JA) consumption on gastroesophageal reflux disease(GERD)-related symptoms.METHODS: Participants included individuals living in Minabe-cho,a well-known JA-growing region,who received specific medical check-ups by the local community health service in 2010.GERD-related symptoms were examined in 1303 Japanese individuals using a validated questionnaire,the Frequency Scale for Symptoms of GERD(FSSG),which consists of 7 questions associated with acid reflux symptoms and 5 questions asking about gastrointestinal dysmotility symptoms.Each question was answered using a 4-point scale,with higher scores indicating more severe GERDrelated symptoms.Subjects were divided into two groups according to their intake of dried and pickled JA: daily intake(≥ 1 JA daily)(392 subjects) and none oroccasional intake(< 1 JA daily)(911 subjects).FSSG scores were compared between subjects who consumed JA daily and those who did not.Next,subjects were stratified by age,gender and Helicobacter pylori(H.pylori) status for subanalyses.RESULTS: Those who ate JA daily were significantly older than those who did not(60.6 ± 10.5 years vs 56.0 ± 11.0 years,P < 0.001).Total FSSG scores were significantly lower in subjects with daily JA intake than in those with none or only occasional intake(2.13 ± 3.14 vs 2.70 ± 3.82,P = 0.005).In particular,subjects who consumed JA daily showed significantly improved FSSG dysmotility scores compared with subjects who did not(1.05 ± 1.58 vs 1.46 ± 2.11,P < 0.001).In contrast,the FSSG reflux score did not differ between subjects with and without daily intake of JA(1.08 ± 1.90 vs 1.24 ± 2.11,P = 0.177).Subanalysis indicated that improvement in dysmotility by JA intake was specifically observed in non-elderly(1.24 ± 1.68 vs 1.62 ± 2.22,P = 0.005) and H.pylori-negative subjects(0.99 ± 1.58 vs 1.57 ± 2.06,P < 0.001).GERD patients(total FSSG score ≥ 8) were less frequently observed among subjects with daily intake of JA as compared to those without daily intake of JA(6.1% vs 9.7%,P = 0.040).CONCLUSION: Daily JA intake may improve digestive dysmotility symptoms,resulting in relief of GERD symptoms.The effect is more obvious in non-elderly and H.pylori-negative subjects. | Takao Maekita Jun Kato Shotaro Enomoto Takeichi Yoshida Hirotoshi Utsunomiya Hideyuki Hayashi Toshiko Hanamitsu Izumi Inoue Yoshimasa Maeda Kosaku Moribata Yosuke Muraki Naoki Shingaki Hisanobu Deguchi Kazuki Ueda Mikitaka Iguchi Hideyuki Tamai Masao Ichinose | 2015 | World Journal of Gastroenterology2015，21，26： | 1 |
| 18 | Synthesis of Ti3SiC2 from powder blend of Ti, Si and TiC显示文摘 | Hitoshi Hashimoto Zheng Ming Suna Yosuke Inoue | 2006 | Journal of Alloys and Compounds2006，，1： | 1 |
| 19 | Three Cases of Serous Oligocystic Adenomas of the Pancreas; Evaluation of Cyst Wall Thickness for Preoperative Differentiation from Mucinous Cystic Neoplasms显示文摘 | Hiroshi Yamaguchi Kousei Ishigami Takahiro Inoue Takashi Eguchi Shigenori Nagata Yosuke Kuroda Yunosuke Nishihara Koji Yamaguchi Masao Tanaka Masazumi Tsuneyoshi | 2008 | Journal of Gastrointestinal Cancer2008，，1： | 1 |
| 20 | DNA Aptamer Raised Against AGEs Blocks the Progression of Experimental Diabetic Nephropathy显示文摘 | Yusuke Kaida Kei Fukami Takanori Matsui Yuichiro Higashimoto Yuri Nishino Nana Obara Yosuke Nakayama Ryotaro Ando Maki Toyonaga Seiji Ueda Masayoshi Takeuchi Hiroyoshi Inoue Seiya Okuda Sho-ichi Yamagishi | 2013 | Diabetes2013，，9： | 1 |
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