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| 1 | Effects of Saikosaponin-D on syndecan-2,matrix metalloproteinases and tissue inhibitor of metalloproteinases-2 in rats with hepatocellular carcinoma显示文摘OBJECTIVE:To investigate effects of Saikosaponin D(SSd) on syndecan-2,matrix metalloproteinases(MMPs) and tissue inhibitor of metalloproteinases-2(TIMP-2) in livers of rat with hepatocellular carcinoma(HCC).METHODS:Male SD rats were divided into control(n=10),model(n=20) and SSd(n=20) groups,and model and SSd groups given intragastric 0.2%(w/v) N-diethylnitrosamine to induce HCC.SSd group received 0.03%(w/v) SSd in saline.Liver samples were analysed immunohistochemically for syndecan-2,MMP-2,MMP-13 and TIMP-2 at 16 weeks.RESULTS:The model group had more malignant nodules than the SSd group;all model-group HCC cells were grade III;SSd-group HCC cells were grades I-II.Controls showed normal hepatic cell phenotypes and no syndecan-2 + staining.Syndecan-2 + staining was greater in the model group(35.2%,P≤0.001) than in controls or the SSd group(16.5%,P ≤ 0.001).The model group had more intense MMP-2 + staining than controls(0.37 vs 0.27,P≤0.01) or the SSd group(0.31 vs 0.37,P≤0.05);and higher MMP-13 + staining(72.55%) than in controls(12.55%,P≤0.001) and SSd group(20.18%,P≤0.01).The model group also had more TIMP-2 + staining(57.2%) than controls(20.9%,P≤0.001) and SSd group(22.7%,P≤0.001).Controls and SSd group showed no difference in TIMP-2 + rates.CONCLUSION:SSd inhibited HCC development,and downregulated expression of syndecan-2,MMP-2,MMP-13 and TIMP-2 in rat HCC liver tissue. | Xiaoli Jia Shuangsuo Dang Yanan Cheng Xin Zhang Mei Li Yaping Li Siyuan Li | 2012 | Journal of Traditional Chinese Medicine2012，32，3： | 12 |
| 2 | Effect of cooling rates on the dendritic morphology transition of Mg–6Gd alloy by in situ X-ray radiography显示文摘The effect of cooling rate on the transition of dendrite morphology of a Mg-6 Gd(wt%) alloy was semiquantitatively analyzed under a constant temperature gradient by using synchrotron X-ray radiographic technique. Results show that equiaxed dendrites, including exotic 'butterfly-shaped' dendrite morphology, dominate at high cooling rate(>1 K/s). When the cooling rate decreases in the range of 0.5–1 K/s, the equiaxed-to-columnar transition takes place, and solute segregates at the center of two long dendrite arms(LDA) of the 'butterfly-shaped' dendrite. When the cooling rate is lower than 0.3 K/s, directional solidification occurs and the columnar dendritic growth direction gradually rotates from the crystalline axis to the thermal gradient direction with an increase in cooling rate. Meanwhile, interface moves faster but the dendrite arm spacing decreases. Floating, collision and rotation of dendrites under convection were also studied in this work. | Yongbiao Wang Liming Peng Yanzhou Ji Xiaoxing Cheng Cunlong Wang Yujuan Wu Yanan Fu Long-Qing Chen | 2018 | Journal of Materials Science & Technology2018，34，7： | 8 |
| 3 | Benefit of everolimus as a monotherapy for a refractory breast cancer patient bearing multiple genetic mutations in the PI3K/AKT/mTOR signaling pathway显示文摘A postmenopausal patient with a diagnosis of estrogen receptor(ER)(+), progesterone receptor(PR)(+), and human epidermal growth factor receptor-2(HER2)(-) breast cancer was reported. The patient refused surgery and was resistant to conventional chemotherapy regimens. Computed tomography and the circulating tumor cell test indicated that the patient's tumor burden increased rapidly even after several chemotherapy sessions. Multiple genetic aberrances in the phosphatidylinositol3-kinases(PI3 K) signaling pathway were detected via next-generation sequencing(NGS)-based liquid biopsy, including a p. G1007 R missense mutation in exon 21 of PIK3 CA(33.61%), a p.L70 fs frameshift mutation in exon 3 of phosphatase and tension homolog deleted on chromosome ten(PTEN)(49.14%), and a p. D1542 Y missense mutation in exon 32 of mammalian target of rapamycin(m TOR)(1.66%). Therefore, only the m TOR inhibitor everolimus was administered to the patient. Partial remission(PR) was observed after 2 months, and sustained stable disease(SD) was observed after a year and a half. Subsequent sequencing showed that the mutation ratio of PIK3 CA decreased to 4.17%, and that the PTEN and m TOR mutations disappeared, which revealed the significant curative effect of everolimus. We report the first case of successful monotherapy treatment using everolimus in a patient with advanced breast cancer bearing mutations in genes involved in the PI3 K/ARK/m TOR signaling pathway. The success of this case highlights the invaluable clinical contribution of NGS-based liquid biopsy, as it successfully provided an optimal therapeutic target for the patient with advanced breast cancer. | Yehui Shi Wenwen Zhang Yingnan Ye Yanan Cheng Lei Han Pengpeng Liu Weipeng Zhao Zhongsheng Tong Jinpu Yu | 2018 | Cancer Biology & Medicine2018，15，3： | 6 |
| 4 | Black phosphorus inverter devices enabled by in-situ aluminum surface modification显示文摘Two-dimensional black phosphorus (BP) generally exhibits a hole-dominated transport characteristic when configured as field-effect transistor devices. The effective control of charge carrier type and concentration is very crucial for the application of BP in complementary electronics. Herein, we report a facile and effective electron doping methodology on BP, through in situ surface modification with aluminum (Al). The electron mobility of few-layer BP is found to be largely enhanced to ~ 10.6 cm^2·V^–1·s^–1 by over 6 times after aluminum modification. In situ photoelectron spectroscopy characterization reveals the formation of Al–P covalent bond at the interface, which can also serve as local gate to tune the transport properties in BP layers. Finally, a spatially-controlled aluminum doping technique is employed to establish a p–n homojunction on a single BP flake, and hence to realize the complementary inverter devices, where the highest gain value of ~ 33 is obtained. | Yue Zheng Zehua Hu Cheng Han Rui Guo Du Xiang Bo Lei Yanan Wang Jun He Min Lai Wei Chen | 2019 | Nano Research2019，12，3： | 5 |
| 5 | Paleomagnetic results from Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane, Tibet, China, and their tectonic implications显示文摘Results of a systematic paleomagnetic study are reported based on Late Carboniferous to Early Permian sedimentary rocks on the north slope of the Tanggula Mountains,in the northern Qiangtang terrane(NQT),Tibet,China.Data revealed that magnetic minerals in limestone samples from the Zarigen Formation(CP^z)are primarily composed of magnetite,while those in sandstone samples from the Nuoribagaribao Formation(Pnr)are dominated by hematite alone,or hematite and magnetite in combination.Progressive thermal,or alternating field,demagnetization allowed us to isolate a stable high temperature component(HTC)in 127 specimens from 16 sites which successfully passed the conglomerate test,consistent with primary remnance.The tilt-corrected mean direction for Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane is D_s=30.2°,I_s=-40.9°,k_s=269.0,a_(95)=2.3°,N=16,which yields a corresponding paleomagnetic pole at 25.7°N,241.5°E(dp/dm=2.8°/1.7°),and a paleolatitude of 23.4°S.Our results,together with previously reported paleomagnetic data,indicate that:(1)the NQT in Tibet,China,was located at a low latitude in the southern hemisphere,and may have belonged to the northern margin of Gondwana during the Late Carboniferous to Early Permian;(2)the Paleo-Tethys Ocean was large during the Late Carboniferous to Early Permian,and(3)the NQT subsequently moved rapidly northwards,perhaps related to the fact that the Paleo-Tethys Ocean was rapidly contracting from the Late Permian to Late Triassic while the Bangong Lake-Nujiang Ocean,the northern branch of the Neo-Tethys Ocean,expanded rapidly during this time. | YANG XingFeng CHENG Xin ZHOU YaNan MA Lun ZHANG XiaoDong YAN ZhaoSheng PENG XiMing SU HaiLun WU HanNing | 2017 | Science China Earth Sciences2017，60，1： | 5 |
| 6 | Synthesis and evaluation of a protic ionic liquid as a multifunctional lubricant additive显示文摘An oil soluble multifunctional protic ionic liquid(IL)was synthesized and its tribological and antioxidant properties in poly alpha olefin(PA04)were investigated.The tribological results demonstrated that the IL significantly reduced friction and wear of PA04.The PA04 blend with IL resulted in an induced oxidation time of 555 min which is 8.2 and 3.5 times higher than that of pure PA04 and PA04 with zinc dialkyl dithiophosphate(ZDDP)for the rotating pressure vessel oxidation test.It is likely that free nonylated diphenylamine acted as a radical scavenger to enhance antioxidant performance,while free bis(2-ethylhexyl)phosphate was more prone to adsorb and react with the metal surface to form a phosphorus-rich tribofilm in order to protect the rubbing surface. | Cheng JIANG Yanan WANG Huaigang SU Weimin LI Wenjing LOU Xiaobo WANG | 2020 | Friction2020，8，3： | 5 |
| 7 | Preliminary Analysis of Diesel-Degrading Bacteria Immobilized on Organic Carriers in Seawater显示文摘Oil pollution in marine environment is becoming increasingly serious. Oil bioremediation by immobilization technology has been widely studied. However, the effect of bacteria immobilization was limited because of lack of nutrients. In this paper, the organic materials(corn straw, corn cob and corn leaf) were used as carriers. The diesel removal rate achieved by the immobilized bacteria was studied, and the effects of nutrients(e.g. nitrogen and phosphorus) released from organic carriers to the immobilized bacteria were analyzed. Test results indicated that a certain amount of nutrients was released from organic carriers. Additionally, the diesel removal rates achieved by different immobilized bacteria were all higher than those achieved by free bacteria. And, the diesel removal rates achieved by bacteria decreased in the following order: bacteria immobilized on corn straw(79%), bacteria immobilized on corn leaf(70%) and bacteria immobilized on corn cob(43%). These findings indicated two aspects, viz.: the carriers porous structure and the nutrients, which were favorable to biodegradation. Finally, the changes in nitrogen and phosphorus contents that were released from different carriers during biodegradation were studied. The results showed that the rate of diesel biodegradation was fast in the initial phase because of the sufficient nutrients released from carriers. Meanwhile, in the final phase, the rate of diesel biodegradation was relatively slow because of few nutrients released from carriers. | Liu Zhixiu Xue Jianliang Wu Yanan Li Menglu Sun Xiyu Cui Hao Cheng Lijie Gao Yu Xiao Xinfeng | 2017 | China Petroleum Processing & Petrochemical Technology2017，19，2： | 4 |
| 8 | Surface charge transfer doping for two-dimensional semiconductor-based electronic and optoelectronic devices显示文摘Doping of semiconductors,i.e.,accurately modulating the charge carrier type and concentration in a controllable manner,is a key technology foundation for modern electronics and optoelectronics.However,the conventional doping technologies widely utilized in silicon industry,such as ion implantation and thermal diffusion,always fail when applied to two-dimensional(2D)materials with atomically-thin nature.Surface charge transfer doping(SCTD)is emerging as an effective and non-destructive doping technique to provide reliable doping capability for 2D materials,in particular 2D semiconductors.Herein,we summarize the recent advances and developments on the SCTD of 2D semiconductors and its application in electronic and optoelectronic devices.The underlying mechanism of STCD processes on 2D semiconductors is briefly introduced.Its impact on tuning the fundamental properties of various 2D systems is highlighted.We particularly emphasize on the SCTD-enabled high-performance 2D functional devices.Finally,the challenges and opportunities for the future development of SCTD are discussed. | Yanan Wang Yue Zheng Cheng Han Wei Chen | 2021 | Nano Research2021，14，6： | 3 |
| 9 | Utilization and quality assessment of digestive endoscopy in China:results from 5-year consecutive nationwide surveys显示文摘Background:Worldwide,the volume and availability of digestive endoscopy have undergone dramatic development in recent years,with increasing attention on quality assurance.We investigated the utilization and quality of digestive endoscopy in China from 2015 to 2019 and developed a quantitative quality evaluation tool for medical institutions.Methods:We invited all tertiary/secondary hospitals in Chinese mainland to participate in the survey annually.The questionnaires included the personnel,annual volume,and quality indicators of endoscopy.An endoscopy quality index(EQI)was developed based on recorded quality indicators using principal component analysis to determine the relative weight.Results:From 2015 to 2019,806,1412,2644,2468,and 2541 hospitals were respectively enrolled in this study.The average annual volume of endoscopy increased from 12,445 to 16,206(1.30-fold)and from 2938 to 4255(1.45-fold)in tertiary and secondary hospitals,respectively.The most obvious growth was observed in diagnostic colonoscopy(1.44-fold for all hospitals after standardization).The proportion of early cancer among all esophageal and gastric cancers during diagnostic esophagogastroduodenoscopy increased from 12.3%(55,210/448,861)to 17.7%(85,429/482,647)and from 11.4%(69,411/608,866)to 16.9%(107,192/634,235),respectively.The adenoma detection rate of diagnostic colonoscopy increased from 14.9%(2,118,123/14,215,592)to 19.3%(3,943,203/20,431,104).The EQI model included 12 quality indicators,incorporating 64.9%(7.792/12)of the total variance into one comprehensive index.According to the EQI measurements,the quality of endoscopy was higher in tertiary hospitals and hospitals in developed areas with higher volume or more endoscopists than that in other hospitals.Conclusions:Digestive endoscopy in China has developed considerably in recent years in terms of both volume and quality.The EQI is a promising tool to quantify the quality of endoscopy at different hospitals. | Lei Xin Ye Gao Zhiyuan Cheng Tianjiao Wang Han Lin Yanan Pang Chang Sun Zengjun Fu Zhaoshen Li Xudong Ma Luowei Wang | 2022 | Chinese Medical Journal2022，135，16： | 3 |
| 10 | Hierarchical particle filter tracking algorithm based on multi-feature fusion显示文摘A hierarchical particle filter(HPF) framework based on multi-feature fusion is proposed.The proposed HPF effectively uses different feature information to avoid the tracking failure based on the single feature in a complicated environment.In this approach,the Harris algorithm is introduced to detect the corner points of the object,and the corner matching algorithm based on singular value decomposition is used to compute the firstorder weights and make particles centralize in the high likelihood area.Then the local binary pattern(LBP) operator is used to build the observation model of the target based on the color and texture features,by which the second-order weights of particles and the accurate location of the target can be obtained.Moreover,a backstepping controller is proposed to complete the whole tracking system.Simulations and experiments are carried out,and the results show that the HPF algorithm with the backstepping controller achieves stable and accurate tracking with good robustness in complex environments. | Minggang Gan Yulong Cheng Yanan Wang Jie Chen | 2016 | Journal of Systems Engineering and Electronics2016，27，1： | 3 |
| 11 | Band-tailored van der Waals heterostructure for multilevel memory and artificial synapse显示文摘Two-dimensional(2D)van der Waals heterostructure(vdWH)-based floating gate devices show great potential for next-generation nonvolatile and multilevel data storage memory.However,high program voltage induced substantial energy consumption,which is one of the primary concerns,hinders their applications in lowenergy-consumption artificial synapses for neuromorphic computing.In this study,we demonstrate a three-terminal floating gate device based on the vdWH of tin disulfide(SnS2),hexagonal boron nitride(h-BN),and few-layer graphene.The large electron affinity of SnS2 facilitates a significant reduction in the program voltage of the device by lowering the hole-injection barrier across h-BN.Our floating gate device,as a nonvolatile multilevel electronic memory,exhibits large on/off current ratio(105),good retention(over 104 s),and robust endurance(over 1000 cycles).Moreover,it can function as an artificial synapse to emulate basic synaptic functions.Further,low energy consumption down to7 picojoule(pJ)can be achieved owing to the small program voltage.High linearity(<1)and conductance ratio(80)in long-term potentiation and depression(LTP/LTD)further contribute to the high pattern recognition accuracy(90%)in artificial neural network simulation.The proposed device with attentive band engineering can promote the future development of energy-efficient memory and neuromorphic devices. | Yanan Wang Yue Zheng Jing Gao Tengyu Jin Enlong Li Xu Lian Xuan Pan Cheng Han Huipeng Chen Wei Chen | 2021 | InfoMat2021，3，8： | 3 |
| 12 | Low-dose intravenous tissue plasminogen activator for acute ischaemic stroke: an alternative or a new standard?显示文摘Background:With the recent publication of a large clinical trial on the use of a lower dose of intravenous(IV)tissue plasminogen activator(tPA)for acute ischaemic stroke(AIS),the concept of using a different dose has been debated.We intend to review the literature on using a lower dose of IV tPA and gain a better understanding of the impact of different IV doses on the treatment of patients with AIS.Methods:A comprehensive literature search of the related topics in PubMed,EMBASE,Web of Science and MEDLINE was carried out.Key words used include low dose IV tPA,thrombolysis,Alteplace and tPA for AIS.Findings were tabulated according to the size of the cohort studied,outcome,adverse event and level of evidence.The results of all studies using lower doses were analysed for efficacy and adverse events.Results:From 1992 to 2016,there were 23 trials that included 10950 patients published on the use of lower doses of IV tPA for AIS.Doses ranged from 0.5,0.6,0.75 to 0.85 mg/kg.Most were observational,retrospective and registry studies.One was a prospective open-label randomised controlled trial.13 trials combined lower doses of IV tPA with a glycoprotein IIb/IIIa inhibitor or thrombectomy.Patients treated with lower doses of IV tPA showed a trend of lower rate of symptomatic intracranial haemorrhage and mortality at 3 months but slightly more disability.Conclusions:Lower doses of IV tPA showed less haemorrhagic events but were not more effective compared with the standard dose.The optimal low dose of IV tPA remains unclear.Patients with AIS with a high risk of developing sypmtomatic intracranial haemorrhage might benefit from lower dose IV tPA,such as 0.6 mg/kg. | Yi Dong Wenjie Cao Xin Cheng Kun Fang Fei Wu Lumeng Yang Yanan Xie Qiang Dong | 2016 | Stroke & Vascular Neurology2016，1，3： | 2 |
| 13 | Surface functionalization on the thermal conductivity of graphene-polymer nanocomposites显示文摘Exploring thermal transport in graphene-polymer nanocomposite is significant to its applications with better thermal properties.Interfacial thermal conductance between graphene and polymer matrix plays a critical role in the improvement of thermal conductivity of graphene-polymer nanocomposite.Unfortunately,it is still challenging to understand the interfacial thermal transport between graphene nanofiller and polymer matrix at small material length scale.To this end,using nonequilibrium molecular dynamics(NEMD)simulations,we investigate the interfacial thermal conductance of graphene-polyethylene(PE)nanocomposite.The influence of functionalization with hydrocarbon chains on the interfacial thermal conductance of graphene-polymer nanocomposites was studied,taking into account the effects of model size and thermal conductivity of graphene.An analytical model is also used to calculate the thermal conductivity of nanocomposite.The results are considered to contribute to the development of new graphene-polymer nanocomposites with tailored thermal properties. | Mingchao Wang Dilini Galpaya Zheng Bo Lai Yanan Xu Cheng Yan | 2014 | International Journal of Smart and Nano Materials2014，5，2： | 2 |
| 14 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
| 15 | CmBES1 is a regulator of boundary formation in chrysanthemum ray florets显示文摘Chrysanthemum(Chrysanthemum morifolium)is an ideal model species for studying petal morphogenesis because of the diversity in the flower form across varieties;however,the molecular mechanisms underlying petal development are poorly understood.Here,we show that the brassinosteroid transcription factor BRI1-EMS-SUPPRESSOR 1(CmBES1)in chrysanthemum(C.morifolium cv.Jinba)is important for organ boundary formation because it represses organ boundary identity genes.Chrysanthemum plants overexpressing CmBES1 displayed increased fusion of the outermost ray florets due to the loss of differentiation of the two dorsal petals,which developed simultaneously with the ventral petals.RNA-seq analysis of the overexpression lines revealed potential genes and pathways involved in petal development,such as CUP-SHAPED COTYLEDON(CUC2),CYCLOIDEA 4(CYC4),genes encoding MADS-box transcription factors and homeodomain-leucine zippers(HD-Zips)and auxin pathway-related genes.This study characterizes the role of CmBES1 in ray floret development by its modulation of flower development and boundary identity genes in chrysanthemum. | Peilei Cheng Yanan Liu Yiman Yang Hong Chen Hua Cheng Qian Hu Zixin Zhang Jiaojiao Gao Jiaxin Zhang Lian Ding Weimin Fang Sumei Chen Fadi Chen Jiafu Jiang | 2020 | Horticulture Research2020，7，1： | 2 |
| 16 | New Maikhanellid Shells and Siphogonuchitid Spicule Bundles from the Cambrian Fortunian Stage of South China显示文摘Maikhanellids are a distinct group of Cambrian Fortunian small shelly fossils by the capshaped profiles and scaly shell ornamentation.According to the individual shell shape and ornamentation feature types of 50 maikhanellids fossils which were collected from Xixiang botia,we confirmed the family Maikhanellidae content of six genera,which are Maikhanella,Ramenta,Purella,Ramentoides,Yunnannopleura and Mediata.Unlike the halkieriid animals whose shells and spicules are articulated on different body parts,maikhanellids were presumably yielded by siphogonuchitid spicules penetrating the intermediate matrix(the 'spicule shell' hypothesis),and this is the reason that some researchers treated maikhanellids and co-occurring siphogonuchitids as synonyms.The affinities of Maikhanellids and siphogonuchitids remain debatable.Here,we report three dimensionally phosphatized maikhanellid shells and siphogonuchitid spicule bundles from the Cambrian Fortunian small shell faunas of South China.They differ from all the previously reported maikhanellids and siphogonuchitids,and may represent new types.The intact and smooth surface underneath the partially preserved scales of the shells challenges the 'spicule-shell' hypothesis.The present siphogonuchitid spicules differ from the maikhanellid scales in size,morphology,and.arrangement pattern,thus the spicules might not be derived from the shells.Whether the shells and spicule bundles were articulated on different body parts of the same animals remains unknown. | LIU Yunhuan ZHANG Yanan SHAO Tiequan TANG Hanhua JIANG Kaituo WANG Qi CHEN Cheng DONG Junyan LIANG Yongchun DAI Jun XUE Jiaqi | 2016 | Acta Geologica Sinica(English Edition)2016，90，5： | 2 |
| 17 | Eopriapulites Sphinx—The Oldest Priapulid-Like Scalidophoran Animal显示文摘Objective Priapulid belong to scalidophoran and is located in the Cycloneuralia branch of the Ecdysozoa.It has survived for more than 50 million years,is a real'living fossil'.Priapulid was extremely prosperous in the Cambrian period.It is a small phylum in the modern ocean;only 18current types have been described.In the Cambrian life,priapulid is one of the most important living organisms | SHAO Tiequan LIU Yunhuan WANG Qi DAI Jun ZHANG Yanan TANG Hanhua LIANG Yongchun CHEN Cheng HU Bo WEI Meng YANG Tingting | 2016 | Acta Geologica Sinica(English Edition)2016，90，4： | 1 |
| 18 | Sulfur Vacancies Tune the Charge Distribution of NiCo_(2)S_(4) for Boosting the Energy Density of Stretchable Yarn‑Based Zn Ion Batteries显示文摘Yarn-based batteries with the dual functions of wearable and energy storage have demonstrated promising potential in wearable energy textiles.However,it is still an urgent problem to construct efficient and flexible electrodes while optimize the configuration of yarn-based batteries to maintain excellent electrochemical performance under different mechanical deformations.Herein,NiCo_(2)S_(4-x) nanotube arrays with tunable S-vacancies are constructed on carbon yarn(CY)(NiCo_(2)S_(4-x)@CY)by a facile hydrothermal strategy.The aqueous zinc-ion batteries(ZIBs)with NiCo_(2)S_(4-x)@CY as cathodes exhibit exceptional discharge capacity(271.7 mAh g^(-1))and outstanding rate performance(70.9%capacity retention at 5 A g^(-1)),and reveal a maximum power density of 6,059.5 W kg^(-1) and a maximum energy density of 432.2 Wh kg^(-1).It is worth noting that the tunable S-vacancies promote the surface reconfiguration and phase transitions of NiCo_(2)S_(4-x),thereby enhancing the conductivity and charge storage kinetics.The high reactivity and cycling stability of NiCo_(2)S_(4-x)@CY can be related to the discharge products of S-doped NiO and CoO.Furthermore,flexible stretchable yarn-based ZIBs with wrapped yarn structures are constructed and exhibit excellent tensile stability and durability under a variety of mechanical deformations.As a proof of concept,the ZIBs integrated into the fabric show excellent electrochemical performance even in response to simultaneous stretching and bending mechanical deformations.The proposed strategy provides novel inspiration for the development of highly efficient and economical yarn-based ZIBs and wearable energy textiles. | Xinyue Cheng Xu Yang Yanan Zhang Pengfei Lv Jixing Yang Fenglin Huang Qufu Wei | 2023 | Advanced Fiber Materials2023，5，2： | 1 |
| 19 | Cr-MCM-41 Molecular Sieves Crystallized at Room Temperature for Reaction of Ethane with CO_(2)显示文摘A series of Cr-containing MCM-41 molecular sieves crystallized at room temperature with a hexagonal and well-ordered structure were synthesized. XRD, FT-IR and DRS UV-Vis techniques were used to characterize the samp.es. The results indicate incorporation of Cr into the MCM-41 framework, and dispersion of some Cr2O3 on the surface or/and in the bulk of the MCM-41. Test of catalytic properties of the series of samples for the topic reaction was carried out using a continuous-flow fixed-bed quartz reactor. Factors influencing the catalytic performance for this title reaction, such as Cr/Si ratio in MCM- 41 and reaction temperature were investigated. The experimental results indicate that over the 5%Cr- MCM-41 a 43.27% conversion of ethane and a 86.70% selectivity for ethylene were achieved in the ethane dehydrogenation with CO2 to ethylene at 973 K. It is suggested that both Cr6+ and Cr3+ are the catalytic activity center. | Yanan Li Xin He Shujie Wu Ke Zhang Guangdong Zhou Jie Liu Kaiji Zhen Tonghao Wu Tiexin Cheng | 2005 | Journal of Natural Gas Chemistry2005，14，4： | 1 |
| 20 | Unbiased transcriptomic analyses reveal distinet effects of immune deficiency in CNS function with and without injury显示文摘The mammalian central nervous system (CNS) is considered an immune privileged system as it is separated from the periphery by the blood brain barrier (BBB). Yet, immune functions have been postulated to heavily influence the functional state of the CNS, especially after injury or during neurodegeneration. There is controversy regarding whether adaptive immune responses are beneficial or detrimental to CNS injury repair. In this study, we utilized immunocompromised SCID mice and subjected them to spinal cord injury (SCI). We analyzed motor function, electrophysiology, histochemistry, and performed unbiased RNA-sequencing. SCID mice displayed improved CNS functional recovery compared to WT mice after SCI. Weighted gene-coexpression network analysis (WGCNA) of spinal cord transcriptomes revealed that SCID mice had reduced expression of immune function-related genes and heightened expression of neural transmission-related genes after SCI, which was confirmed by immunohistochemical analysis and was consistent with better functional recovery. Transcriptomic analyses also indicated heightened expression of neurotransmission-related genes before injury in SCID mice, suggesting that a steady state of immune-deficiency potentially led to CNS hyper-connectivity. Consequently, SCID mice without injury demonstrated worse performance in Morris water maze test. Taken together, not only reduced inflammation after injury but also dampened steady-state immune function without injury heightened the neurotransmission program, resulting in better or worse behavioral outcomes respectively. This study revealed the intricate relationship between immune and nervous systems, raising the possibility for therapeutic manipulation of neural function via immune modulation. | Dandan Luo Weihong Ge Xiao Hu Chen Li Chia-Ming Lee Liqiang Zhou Zhourui Wu Juehua Yu Sheng Lin Jing Yu Wei Xu Lei Chen Chong Zhang Kun Jiang Xingfei Zhu Haotian Li Xinpei Gao Yanan Geng Bo Jing Zhen Wang Changhong Zheng Rongrong Zhu Qiao Yan Quan Lin Keqiang Ye Yi E. Sun Liming Cheng | 2019 | Protein & Cell2019，10，8： | 1 |
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