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| 1 | Ficolin A exacerbates severe H1N1 influenza virus infection-induced acute lung immunopathological injury via excessive complement activation显示文摘Severe pandemic influenza A(H1N1)2009 virus(pH1N1)infection causes significant morbidity and mortality.We and other groups have reported that immunopathological damage induced by excessive pulmonary inflammation plays a critical role in the pathogenesis of severe pneumonia and provides novel strategies for the treatment of severe influenza infection[1–3].The complement system plays critical roles in both innate and adaptive immunity by activating the classical,alternative and lectin pathways[4]. | Xu Wu Linlin Bao Ziqi Hu Duoduo Yao Fengdi Li Hui Li Xiaoxue Xu Yunqing An Xi Wang Bin Cao Xulong Zhang | 2021 | Cellular & Molecular Immunology2021，18，9： | 6 |
| 2 | Oxygen vacancy-engineered BaTiO_(3)nanoparticles for synergistic cancer photothermal,photodynamic,and catalytic therapy显示文摘With the rapid development of photo-responsive nanomaterials,photo-triggered therapeutic strategies such as photothermal therapy(PTT)and photodynamic therapy(PDT)have been new alternatives to current cancer therapeutic methods.Herein,we have fabricated oxygen vacancy-engineered BaTiO_(3)(BTO-Ov)nanoparticles(NPs)for near-infrared(NIR)light-triggered PTT,PDT,and catalytic therapy cooperatively for significantly improving cancer therapy.Compared to pristine BaTiO_(3)nanoparticles,BTO-Ov has stronger NIR light absorption and narrower band gap structure,which results in superior photothermal conversion and superoxide radical generation capabilities through PTT and PDT.Meanwhile,due to the existence of Ti^(3+),BTO-Ov also exhibits peroxidase(POD)-like activity to produce hydroxyl radical under tumor environment,which can be further improved under 808 nm light irradiation.Both in vitro and in vivo results demonstrate that such a multifunctional therapeutic nanoplatform can achieve a high therapeutic efficacy triggered by a single NIR light irradiation.The defect engineering strategy can be used as a general approach to fabricate multifunctional cancer therapeutic nanoplatform. | Yiming Ding Zhuo Wang Zeyu Zhang Yunchao Zhao Shangyu Yang Yalong Zhang Shuncheng Yao Shaobo Wang Tian Huang Yang Zhang Linlin Li | 2022 | Nano Research2022，15，8： | 3 |
| 3 | Prediction of the Maturity of Greenhouse Grapes Based on Imaging Technology显示文摘To predict grape maturity in solar greenhouses,a plant phenotype-monitoring platform(Phenofix,France)was used to obtain RGB images of grapes from expansion to maturity.Horizontal and longitudinal diameters,compactness,soluble solid content(SSC),titratable acid content,and the SSC/acid of grapes were measured and evaluated.The color values(R,G,B,H,S,andI)of the grape skin were determined and subjected to a back-propagation neural network algorithm(BPNN)to predict grape maturity. | Xinguang Wei Linlin Wu Dong Ge Mingze Yao Yikui Bai | 2022 | Plant Phenomics2022，4，1： | 3 |
| 4 | Large-scale fabrication of re duce d graphene oxide-sulfur composite films for flexible lithium-sulfur batteries显示文摘The rapid development of flexible electronic devices requires the design of flexible energy-storage devices. Lithium-sulfur(Li-S) batteries are attracting much interest due to their high energy density. Therefore, flexible Li-S batteries with high areal capacity are desired. Herein, we fabricated freestanding reduced graphene oxide-sulfur(RGO@S) composite films with a cross-linked structure using a blade coating technique, followed by a subsequent chemical reduction. The porous cross-linked structure endows the composite films with excellent electrochemical performance. The batteries based on RGO@S composite films could exhibit a high discharge capacity of 1381 m Ah/g at 0.1 C and excellent cycle stability. Furthermore, the freestanding composite film possesses excellent conductivity and high mechanical strength. Therefore, they can be used as the cathodes of flexible Li-S batteries. As a proof of concept, soft-packaged Li-S batteries were assembled and remained stable electrochemical performance under different bending states. | Yue Liu Minjie Yao Linlin Zhang Zhiqiang Niu | 2019 | Journal of Energy Chemistry2019，28，11： | 3 |
| 5 | Surface Oxygen Injection in Tin Disulfide Nanosheets for Efficient CO_(2) Electroreduction to Formate and Syngas显示文摘Surface chemistry modification represents a promising strategy to tailor the adsorption and activation of reaction intermediates for enhancing activity.Herein,we designed a surface oxygen-injection strategy to tune the electronic structure of SnS_(2) nanosheets,which showed effectively enhanced electrocatalytic activity and selectivity of CO_(2) reduction to formate and syngas(CO and H_(2)).The oxygen-injection SnS_(2) nanosheets exhibit a remarkable Faradaic efficiency of 91.6%for carbonaceous products with a current density of 24.1 mA cm^(−2) at−0.9 V vs RHE,including 83.2%for formate production and 16.5%for syngas with the CO/H_(2) ratio of 1:1.By operando X-ray absorption spectroscopy,we unravel the in situ surface oxygen doping into the matrix during reaction,thereby optimizing the Sn local electronic states.Operando synchrotron radiation infrared spectroscopy along with theoretical calculations further reveals that the surface oxygen doping facilitated the CO_(2) activation and enhanced the affinity for HCOO*species.This result demonstrates the potential strategy of surface oxygen injection for the rational design of advanced catalysts for CO_(2) electroreduction. | Tao Chen Tong Liu Tao Ding Beibei Pang Lan Wang Xiaokang Liu Xinyi Shen Sicong Wang Dan Wu Dong Liu Linlin Cao Qiquan Luo Wei Zhang Wenkun Zhu Tao Yao | 2021 | Nano-Micro Letters2021，13，11： | 3 |
| 6 | Influence of algal bloom degradation on nutrient release at the sediment–water interface in Lake Taihu, China显示文摘 | Mengyuan Zhu Guangwei Zhu Linlin Zhao Xin Yao Yunlin Zhang Guang Gao Boqiang Qin | 2013 | Environmental Science and Pollution Research2013，，3： | 2 |
| 7 | Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals显示文摘 | August Y Huang Xiaojing Xu Adam Y Ye Qixi Wu Linlin Yan Boxun Zhao Xiaoxu Yang Yao He Sheng Wang Zheng Zhang Bowen Gu Han-Qing Zhao Meng Wang Hua Gao Ge Gao Zhichao Zhang Xiaoling Yang Xiru Wu Yuehua Zhang Liping Wei | 2014 | Cell Research2014，24，11： | 2 |
| 8 | An active vibration control method based on energy-fuzzy for cantilever structures excited by aerodynamic loads显示文摘In wind tunnel tests for the full-model fixed with sting,the low structural damping of the long cantilever sting results in destructive low-frequency and large-amplitude vibration.In order to obtain high-quality wind tunnel test data and ensure the safety of wind tunnel tests,an energy-fuzzy adaptive PD(Proportion Differentiation)control method is proposed.This method is used for active vibration control of a cantilever structure under variable aerodynamic load excitation,and real-time adjustment of parameters is achieved according to the system characteristics of vibration energy.Meanwhile,a real-time method is proposed to estimate the real-time vibration energy through the vibration acceleration signal,and the average exciting power of aerodynamic load is obtained by deducting the part of the power contributed by the vibration suppressor from the total power.Furthermore,an energy-fuzzy adaptive PD controller is proposed to achieve adaptive control to the changes of the aerodynamic load.Besides,the subsonic and transonic experiments were carried out in wind tunnel,the results revealed that comparing to fixed gain PD controllers,the energy-fuzzy adaptive PD controller maintains higher performance. | Wei LIU Weixiao LIU Mengde ZHOU Linlin TANG Qinqin WANG Zhengquan WEN Zhuang YAO Xiaojing YUAN | 2021 | Chinese Journal of Aeronautics2021，34，9： | 2 |
| 9 | Characteristics of carotid artery disease (CAD) and presenting cerebrovascular symptoms in an aged group显示文摘 | Qingwei Chen Ying Liu Linlin Pei Dazhi Ke Guiqiong Li Wei Deng Wuwei Yao | 2009 | The International Journal of Cardiovascular Imaging2009，，2： | 1 |
| 10 | Recent Progress in Nanoscale Covalent Organic Frameworks for Cancer Diagnosis and Therapy显示文摘Covalent organic frameworks(COFs)as a type of porous and crystalline covalent organic polymer are built up from covalently linked and periodically arranged organic molecules.Their precise assembly,welldefined coordination network,and tunable porosity endow COFs with diverse characteristics such as low density,high crystallinity,porous structure,and large specific-surface area,as well as versatile functions and active sites that can be tuned at molecular and atomic level.These unique properties make them excellent candidate materials for biomedical applications,such as drug delivery,diagnostic imaging,and disease therapy.To realize these functions,the components,dimensions,and guest molecule loading into COFs have a great influence on their performance in various applications.In this review,we first introduce the influence of dimensions,building blocks,and synthetic conditions on the chemical stability,pore structure,and chemical interaction with guest molecules of COFs.Next,the applications of COFs in cancer diagnosis and therapy are summarized.Finally,some challenges for COFs in cancer therapy are noted and the problems to be solved in the future are proposed. | Shuncheng Yao Zhirong Liu Linlin Li | 2021 | Nano-Micro Letters2021，13，11： | 1 |
| 11 | Geochemical characteristics of amino acids in sediment of Lake Taihu, a large, shallow, eutropic freshwater lake of China 显示文摘 | YAO Xin ZHU Guangwel CAI Linlin | 2012 | Aquatic Geochemistry2012，18，3： | 1 |
| 12 | Means of Eliminating Electrolytic Capacitor in AC/DC Power Supplies for LED Lightings显示文摘 | Linlin Gu Xinbo Ruan Ming Xu Kai Yao | | 0，，05： | 1 |
| 13 | Influence of algal bloom degradation on nutrient release at the sediment–water interface in Lake Taihu, China显示文摘 | Mengyuan Zhu Guangwei Zhu Linlin Zhao Xin Yao Yunlin Zhang Guang Gao Boqiang Qin | 2013 | Environmental Science and Pollution Research2013，，3： | 1 |
| 14 | Projection of hydrothermal condition in Central Asia under four SSP-RCP scenarios显示文摘Hydrothermal condition is mismatched in arid and semi-arid regions,particularly in Central Asia(including Kazakhstan,Kyrgyzstan,Tajikistan,Uzbekistan,and Turkmenistan),resulting many environmental limitations.In this study,we projected hydrothermal condition in Central Asia based on bias-corrected multi-model ensembles(MMEs)from the Coupled Model Intercomparison Project Phase 6(CMIP6)under four Shared Socioeconomic Pathway and Representative Concentration Pathway(SSP-RCP)scenarios(SSP126(SSP1-RCP2.6),SSP245(SSP2-RCP4.5),SSP460(SSP4-RCP6.0),and SSP585(SSP5-RCP8.5))during 2015-2100.The bias correction and spatial disaggregation,water-thermal product index,and sensitivity analysis were used in this study.The results showed that the hydrothermal condition is mismatched in the central and southern deserts,whereas the region of Pamir Mountains and Tianshan Mountains as well as the northern plains of Kazakhstan showed a matched hydrothermal condition.Compared with the historical period,the matched degree of hydrothermal condition improves during 2046-2075,but degenerates during 2015-2044 and 2076-2100.The change of hydrothermal condition is sensitive to precipitation in the northern regions and the maximum temperatures in the southern regions.The result suggests that the optimal scenario in Central Asia is SSP126 scenario,while SSP585 scenario brings further hydrothermal contradictions.This study provides scientific information for the development and sustainable utilization of hydrothermal resources in arid and semi-arid regions under climate change. | YAO Linlin ZHOU Hongfei YAN Yingjie LI Lanhai SU Yuan | 2022 | Journal of Arid Land2022，14，5： | 1 |
| 15 | Characteristics of carotid artery disease (CAD) and presenting cerebrovascular symptoms in an aged group显示文摘 | Qingwei Chen Ying Liu Linlin Pei Dazhi Ke Guiqiong Li Wei Deng Wuwei Yao | 2009 | The International Journal of Cardiovascular Imaging2009，，2： | 1 |
| 16 | Resolving the variability of CDOM fluorescence to differentiate the sources and fate of DOM in Lake Taihu and its tributaries显示文摘 | Xin Yao Yunlin Zhang Guangwei Zhu Boqiang Qin Longqing Feng Linlin Cai Guang Gao | 2010 | Chemosphere2010，，2： | 1 |
| 17 | Metformin capped Cu_(2)(OH)_(3)Cl nanosheets for chemodynamic wound disinfection显示文摘Recently,the development of chemodynamic therapy(CDT)offers a potential approach for fighting bacteria and treating infectious diseases,in which those CDT nanoagents can catalyze the generation of hydroxyl radicals(·OH)to destroy bacteria.In this work,to improve the efficiency of CDT,we have designed a new kind of metformin(Met)-capped two-dimensional Cu_(2)(OH)_(3)Cl nanosheets(CuOHCl-Met NSs)with good monodispersity,highly positive charge,and good biocompatibility for improving antibacterial effect and accelerating wound healing.With the capped Met,CuOHCl-Met NSs can effectively kill bacteria under a low concentration(6μg·mL^(−1))and a short treatment time(in 15 min),showing great advantages over the counterpart without Met.In vivo results demonstrated that CuOHCl-Met NSs accelerated the tissue regeneration of staphylococcus aureus-infected dermal wounds.This study provides a new pathway for improving efficiency of CDT nanoagent through using old drug. | Xueyu Wang Shaobo Wang Jiao Gao Shuncheng Yao Teng Xu Yunchao Zhao Zeyu Zhang Tian Huang Shu Yan Linlin Li | 2023 | Nano Research2023，16，3： | 0 |
| 18 | Interface construction of NiCo LDH/NiCoS based on the 2D ultrathin nanosheet towards oxygen evolution reaction显示文摘Carbon-free hydrogen as a promising clean energy source can be produced with electrocatalysts via water electrolysis.Oxygen evolution reaction(OER)as anodic reaction determines the overall efficiency of water electrolysis due to sluggish OER kinetics.Thus,it’s much desirable to explore the efficient and earth-abundant transition-metal-based OER electrocatalysts with high current density and superior stability for industrial alkaline electrolyzers.Herein,we demonstrate a significant enhancement of OER kinetics with the hybrid electrocatalyst arrays in alkaline via judiciously combining earth-abundant and ultrathin NiCo-based layered double hydroxide(NiCo LDH)nanosheets with nickel cobalt sulfides(NiCoS)with a facile metal-organic framework(MOF)-template-involved surface sulfidation process.The obtained NiCo LDH/NiCoS hybrid arrays exhibits an extremely low OER overpotential of 308 mV at 100 mA·cm^(−2),378 mV at 200 mA·cm^(−2)and 472 mV at 400 mA·cm^(−2)in 1 M KOH solution,respectively.A much low Tafel slope of 48 mV·dec^(−1)can be achieved.Meanwhile,with the current density from 50 to 250 mA·cm^(−2),the NiCo-LDH/NiCoS hybrid arrays can run for 25 h without any degradation.Our results demonstrate that the construction of hybrid arrays with abundant interfaces of NiCo LDH/NiCoS can facilitate OER kinetics via possible modulation of binding energy of O-containing intermediates in alkaline media.The present work would pave the way for the development of lowcost and efficient OER catalysts and industrial application of water alkaline electrolyzers. | Jiahui Li Lili Wang Haojia He Yiquan Chen Zirui Gao Na Ma Bing Wang Linlin Zheng Rulin Li Yujia Wei Junqing Xu Yao Xu Bowen Cheng Zhen Yin Ding Ma | 2022 | Nano Research2022，15，6： | 0 |
| 19 | Effect of semi-continuous water washing on the combustion behaviors of agricultural organic solid waste显示文摘Combustion of agricultural organic solid waste(AOSW)was an ideal solution for their resource utilization in view of their massive annual production and great potential for reduction of fossil fuel utilization.However,high alkali and alkaline earth metals(AAEMs)content in the feedstock can arose severe fouling and slagging issues and thus prohibiting its vast utilization.In this study,a semi-continuous water washing method was proposed to preliminarily remove AAEMs from agricultural organic solid waste and its effects on the combustion behaviors of washed solid product were investigated.Results showed that the combustion index S were improved to 2.63×10-6,over 68%of the total ashes were removed from the cotton stalk,and 96.3%,89.0%and 74.7%of K,Na and Mg were effectively removed,respectively.Moreover,the softening temperature of low temperature ash from the washed sample was as high as 1450◦C,538◦C higher than the low temperature ash from the original sample;the base acid ratio and fouling index were improved from high slagging and fouling risk(1.7 and 90.8)of the original organic solid waste to low and medium risk(0.4 and 3.5),respectively.All these results signified the contributing effect of proposed semi-continuous water washing method on the combustion of agricultural organic solid waste.In a word,this study provided a promising method for fouling and slagging inhibition during the agricultural organic solid waste combustion. | Xiangxi Wang Zhenzhong Hu Jinrong Ma Linlin Yi Jian Li Yanfeng Cheng Jianfei Ma Na An Feng Wang Xian Li Junjun Yan Bo Wei Yue Li Guangqian Luo Hong Yao | 2023 | Carbon Resources Conversion2023，6，1： | 0 |
| 20 | Numerical Simulation of the Influence of Pore Structure on Resistivity, Formation Factor and Cementation Index in Tight Sandstone显示文摘Tight sandstone,with severe diagenesis and complex pore structure,differs greatly from conventional sandstone in terms of rock electrical parameters.In subsurface rock electrical experiments,various electrical parameters are confounded and can only be analyzed qualitatively.The lack of quantitative analysis for each individual electrical parameter presents a challenge for the evaluation of oil and gas saturation in tight sandstone.Based on the 2D pore-throat model and the features of pore structure in the tight sandstone of the Penglaizhen and Shaximiao Formations in the upper and middle Jurassic of the Western Sichuan Depression,this paper presents 3D micro pore-throat models for three types of tight sandstone.It proposes a finite element-based rock electrical simulation method to analyze the influence of pore structure parameters,such as throat radius and throat tortuosity,on electrical parameters such as resistivity,formation factor,and cementation index quantitatively.The research revealed the following results:(1)Throats of tight sandstone usually have lamellar or curved lamellar shapes that are slender and narrow.The lamellar throat used in the proposed porethroat model is more consistent with the features of tight sandstone than the tubular throat used in the original model.(2)The throat determines the conductivity of tight sandstone.The throat parallel to the electric potential has the greatest influence on conductivity,and the throat perpendicular to the potential has the least influence.(3)In tight sandstone grades I to III,as the porosity decreases,the formation factor increases and the cementation index decreases.(4)The results of the rock electrical simulation are consistent with the results of the rock electrical experiment,which indicates that the proposed rock electrical simulation method of tight sandstone is effective and accurate. | WU Feng WEN Zhu YAO Cong WANG Xianhu XI Yanping CONG Linlin | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 0 |
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