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| 1 | Current status of laparoscopic and robotassisted nerve-sparing radical cystectomy in male patients显示文摘During radical cystectomy(RC),the neurovascular bundles are easily removed or damaged,leading to varying rates of incontinence and erectile dysfunction.The nervesparing technique was developed to preserve urinary and erectile function.The adoption of laparoscopic and robot-assisted technology has improved visualization and dexterity of pelvic surgeries,thus facilitate the nerve-sparing technique.Although nerve-sparing RC is technically similar with nerve-sparing radical prostatectomy,there are still some anatomical differences.There are mainly three different types of nerve-sparing techniques.Pelvic lymph node dissection(PLND)is another important factor to influence erectile function and urinary continence.Nerve-sparing laparoscopic radical cystectomy(LRC)and robot-assisted radical cystectomy(RARC)may be an optimal treatment choice in well-selected younger patients with lowvolume,organ-confined disease.We should attempt to do,whenever possible,a nerve-sparing cystectomy at least on oneside.However,due to the need of a well-refined surgical technique,nerve-sparing LRC and RARC is now being performed only by experienced urological surgeons. | Jian Huang Xinxiang Fan Wen Dong | 2016 | Asian Journal of Urology2016，3，3： | 7 |
| 2 | A Novel Green Preparation ofα,α′-Bis(substituted benzylidene)-cycloalkanones Promoted by FeCl3·6H2O in Ionic Liquid显示文摘α, α'-Bis(substituted benzylidene)cycloalkanones were efficiently prepared fromcycloalkanones and benzaldehydes in [bmim][BF4] by using iron(Ⅲ) chloride hexahydrate as acatalyst. It is shown that [bmim][BF4] and iron(Ⅲ) chloride hexahydrate can be quantitativelyrecovered and be reused effectively for many times. Compared with the known methods, thisnovel process has the advantage of being an environmentally benign process together with goodyields and mild reaction conditions. | Xin Ying ZHANG, Xue Sen FAN, Hong Ying NIU, Jian Ji WANGSchool of Chemical and Environmental Sciences, Henan Normal University, Key Laboratory ofEnvironmental Science and Engineering of Henan Education Department,Xinxiang 453002 | 2003 | Chinese Chemical Letters2003，14，10： | 5 |
| 3 | A nomogram for individualized estimation of survival among adult patients with adrenocortical carcinoma after surgery:a retrospective analysis and multicenter validation study显示文摘Background:Clinical outcome of adrenocortical carcinoma(ACC)varies because of its heterogeneous nature and reliable prognostic prediction model for adult ACC patients is limited.The objective of this study was to develop and externally validate a nomogram for overall survival(OS)prediction in adult patients with ACC after surgery.Methods:Based on the data from the Surveillance Epidemiology,and End Results(SEER)database,adults patients diagnosed with ACC between January 1988 and December 2015 were identified and classified into a training set,comprised of 404 patients diagnosed between January 2007 and December 2015,and an internal validation set,com-prised of 318 patients diagnosed between January 1988 and December 2006.The endpoint of this study was OS.The nomogram was developed using a multivariate Cox proportional hazards regression algorithm in the training set and its performance was evaluated in terms of its discriminative ability,calibration,and clinical usefulness.The nomogram was then validated using the internal SEER validation,also externally validated using the Cancer Genome Atlas set(TCGA,82 patients diagnosed between 1998 and 2012)and a Chinese multicenter cohort dataset(82 patients diag-nosed between December 2002 and May 2018),respectively.Results:Age at diagnosis,T stage,N stage,and M stage were identified as independent predictors for OS.A nomo-gram incorporating these four predictors was constructed using the training set and demonstrated good calibration and discrimination(C-index 95%confidence interval[CI],0.715[0.679-0.751]),which was validated in the internal validation set(C-index[95%CI],0.672[0.637-0.707]),the TCGA set(C-index[95%CI],0.810[0.732-0.888])and the Chi-nese multicenter set(C-index[95%CI],0.726[0.633-0.819]),respectively.Encouragingly,the nomogram was able to successfully distinguished patients with a high-risk of mortality in all enrolled patients and in the subgroup analyses.Decision curve analysis indicated that the nomogram was clinically useful and applicable.Conclusions:The study presents a nomogram that incorporates clinicopathological predictors,which can accurately predict the OS of adult ACC patients after surgery.This model and the corresponding risk classification system have the potential to guide therapy decisions after surgery. | Jianqiu Kong Junjiong Zheng Jinhua Cai Shaoxu Wu Xiayao Diao Weibin Xie Xiong Chen Chenyi Liao Hao Yu Xinxiang Fan Chaowen Huang Zhuowei Liu Wei Chen Qiang Lv Haide Qin Jian Huang Tianxin Lin | 2019 | Cancer Communications2019，39，1： | 3 |
| 4 | Short- and Long-term Outcomes after Laparoscopic and Open Hepatectomy for Hepatocellular Carcinoma: A Global Systematic Review and Meta-analysis显示文摘 | Zi Yin Xinxiang Fan Hua Ye Dong Yin Jie Wang | 2013 | Annals of Surgical Oncology2013，，4： | 2 |
| 5 | Comparison of transperitoneal and retroperitoneal laparoscopic nephrectomy for renal cell carcinoma: a systematic review and meta‐analysis显示文摘 | Xinxiang Fan Kewei Xu Tianxin Lin Hao Liu Zi Yin Wen Dong Hai Huang Jian Huang | 2012 | BJU Int2012，，： | 2 |
| 6 | Systematic review and meta-analysis of comparative studies reporting early outcomes after robot-assisted radical cystectomy versus open radical cystectomy显示文摘 | Kaiwen Li Tianxin Lin Xinxiang Fan Kewei Xu Liangkuan Bi Yu Duan Yu Zhou Min Yu Jielin Li Jian Huang | 2013 | Cancer Treatment Reviews2013，，： | 1 |
| 7 | Laparoendoscopic Single-Site Nephrectomy Compared with Conventional Laparoscopic Nephrectomy: A Systematic Review and Meta-analysis of Comparative Studies <ce:link locator='eulogo1'/>显示文摘 | Xinxiang Fan Tianxin Lin Kewei Xu Zi Yin Hai Huang Wen Dong Jian Huang | 2012 | European Urology2012，，4： | 1 |
| 8 | Comparison of transperitoneal and retroperitoneal laparoscopic nephrectomy for renal cell carcinoma: a systematic review and meta‐analysis显示文摘 | Xinxiang Fan Kewei Xu Tianxin Lin Hao Liu Zi Yin Wen Dong Hai Huang Jian Huang | 2012 | BJU Int2012，，4： | 1 |
| 9 | In vitro selection of salinity tolerant variants from triploid bermudagrass (Cynodon transvaalensis?×?C. dactylon) and their physiological responses to salt and drought stress显示文摘 | Shaoyun Lu Xinxiang Peng Zhenfei Guo Gengyun Zhang Zhongcheng Wang Congying Wang Chaoshu Pang Zhen Fan Jihua Wang | 2007 | Plant Cell Reports2007，，8： | 1 |
| 10 | Gemcitabine Compared With Gemcitabine and S-1 Combination Therapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis显示文摘 | Doudou Li Changhao Chen Yu Zhou Rufu Chen Xinxiang Fan Zhuofei Bi Zhihua Li Yimin Liu | 2015 | Medicine2015，，35： | 1 |
| 11 | Studies on the Absorption of NO_2 by Polyethylene Glycol and the Oxidizing Properties of the Resulting Absorbent Product显示文摘PEG (Polyethylene glycol average molecular weight 300) is used as absorbent of NO2. The absorption efficiency is found to reach up to 97%. The absorbing product, PEG NO2, can be used to cleave benzyl ethers mildly and selectively to benzaldehyde and corresponding fatty alcohols, showing that PEG is a valuable oxidizing agent of benzyl ethers. As a carrier of NO2.PEG can be recovered and utilized repeatedly after the oxidation. | Xue Sen FAN Qing Zhi ZHANG Xin Ying ZRANG Sen Song ZHANG (Department of Chemistry, Henan Normal University, Xinxiang, 453002) | 1997 | Chinese Chemical Letters1997，8，9： | 0 |
| 12 | Characteristics of diffusion-tensor imaging for healthy adult rhesus monkey brains显示文摘Diffusion-tensor imaging can be used to observe the microstructure of brain tissue.Fractional anisotropy reflects the integrity of white matter fibers.Fractional anisotropy of a young adult brain is low in gray matter,high in white matter,and highest in the splenium of the corpus callosum.Thus,we selected the anterior and posterior limbs of the internal capsule,head of the caudate nucleus,semioval center,thalamus,and corpus callosum(splenium and genu)as regions of interest when using diffusion-tensor imaging to observe fractional anisotropy of major white matter fiber tracts and the deep gray matter of healthy rhesus monkeys aged 4–8 years.Results showed no laterality differences in fractional anisotropy values.Fractional anisotropy values were low in the head of caudate nucleus and thalamus in gray matter.Fractional anisotropy values were highest in the splenium of corpus callosum in the white matter,followed by genu of the corpus callosum and the posterior limb of the internal capsule.Fractional anisotropy values were lowest in the semioval center and posterior limb of internal capsule.These results suggest that fractional anisotropy values in major white matter fibers and the deep gray matter of 4–8-year-old rhesus monkeys are similar to those of healthy young people. | Xinxiang Zhao Jun Pu Yaodong Fan Xiaoqun Niu Danping Yu Yanglin Zhang | 2013 | Neural Regeneration Research2013，8，31： | 0 |
| 13 | PD-1/L1 inhibitors can improve but not replace chemotherapy for advanced urothelial carcinoma:A systematic review and network meta-analysis显示文摘Background:Programmed cell death-1/ligand 1 inhibitors are a new treatment strategy for advanced urothelial carcinoma.Therefore,a comparative evaluation of their efficacy and toxicity compared with chemotherapy is necessary.Methods:We comprehensively searched PubMed,Web of Science,Embase,and Cochrane Library databases and performed a meta-analysis of randomized controlled trials up to July 2021.We considered overall survival as the primary outcome,and progression-free survival,objective response rate,and treatment-related adverse events as secondary outcomes.Results:Overall,3584 patients from five studies were evaluated.Compared with first-line chemotherapy,programmed cell death-1/ligand 1 inhibitors were significantly associated with worse progression-free survival(p<0.001)and adverse objective response rates(p<0.001).However,the treatments were not significantly different in terms of overall survival(p=0.33).Compared with second-line chemotherapy,programmed cell death-1/ligand 1 inhibitors significantly improved overall survival(p<0.001),and there was no statistically significant difference in progression-free survival(p=0.89)or objective response rate(p=0.34).Compared with chemotherapy,programmed cell death-1/ligand 1 inhibitors were well tolerated(first-line chemotherapy:p<0.001;second-line chemotherapy:p<0.001).Conclusions:The efficacy of programmed cell death-1/ligand 1 inhibitors in patients with advanced urothelial carcinoma is not superior to that of first-line platinum-based chemotherapy but is better than second-line chemotherapy;however,programmed cell death-1/ligand 1 inhibitors are safer than first-and second-line chemotherapy and have a broader prospect for use in combination therapy. | Longkun Mao Meihua Yang Xinxiang Fan Wenjie Li Xiaodong Huang Wang He Tianxin Lin Jian Huang | 2023 | Cancer Innovation2023，2，3： | 0 |
| 14 | On-line solid-phase extraction using alizarin violet functionalized silica gel for determination of trace lead in environmental samples and wastewater by sequential injection spectrophotometry显示文摘Trace of Pb(Ⅱ) has been on-line separated and enriched from environmental samples and wastewater by using the self-made alizarin violet functionalized silica gel micro-column coupling with a sequential injection sampling technology. The determination is based on the color reaction of Pb(Ⅱ) with iodide and crystal violet to form an ionic association complex in the presence of polyvinyl alcohol and hydrochloric acid. The use of the microcolumn can prevent the interference of most familiar metal ions, and therefore improve the selectivity and sensitivity of this analytical technique. The proposed method was used for the determination of Pb(Ⅱ) in environmental samples and wastewater. No statistically significant difference was observed between the results determined by the present method and atomic absorption spectrometry. | FAN Jing, ZHU GuiFen, WANG HaiBo & WANG JianJi Henan Key Laboratory for Environmental Pollution Control Key Laboratory for Yellow and Huai River Water Environmental and Pollution Control, Ministry of Education School of Chemical and Environmental Sciences, Henan Normal University, Xinxiang 453007, China | 2011 | Science China Chemistry2011，54，6： | 0 |
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