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| 1 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021,31,4: | 16 |
| 2 | Chaperone proteins identified from synthetic proteasome inhibitor-induced inclusions in PC12 cells by proteomic analysis显示文摘女伴蛋白质在 Lewy 身体是重要的,但是女伴蛋白质的侧面不完全地被解开。Proteomic 分析被用来为进一步的学习决定蛋白质候选人。这里,从导致代理人的包括识别潜在的女伴蛋白质,我们执行了包括在为 48 h 暴露于 10 M 希腊语的第二十三个字母的 PC12 房间形成了的导致的人工地合成的 proteasome 禁止者(希腊语的第二十三个字母) 的 proteomic 分析。用通过指纹对多重蛋白质数据库寻找了的肽质量的生物化学的分别, 2-D 电气泳动,和鉴定,我们反复从导致希腊语的第二十三个字母的包括识别了八可再现的女伴蛋白质。这些, 58 kDa 葡萄糖调整了蛋白质, 75 kDa 葡萄糖调整了蛋白质,并且钙绑定蛋白质 1 是最新识别了。其它五被报导了是 Lewy 身体的一致部件。这些调查结果建议三潜在的女伴蛋白质可能在 proteasome 抑制下面在 PC12 房间被招募到导致希腊语的第二十三个字母的包括。 | Xing'an Li Yingjiu Zhang Yihong Hu Ming Chang Tao Liu Danping Wang Yu Zhang Lei Zhang Linsen Hu | 2008 | Acta Biochimica et Biophysica Sinica2008,40,5: | 4 |
| 3 | Blue revolution for food security under carbon neutrality: A case from the water-saving and drought-resistance rice显示文摘The increasing concentration of greenhouse gases(GHGs)in Earth's atmosphere leads to global warming,which further causes a series of climate changes and does great harm to both human society and natural ecosystems.Agricultural GHG emissions,mainly in theform of methane(CH4)and nitrous oxide(N2O),areasignificantsourceofGHGs,accountingfor~14%total global GHGs(Zhang et al.,2022).One major source of agricultural GHGs is CH4 emissions from rice paddies,which is responsiblefor~10%-12%ofhuman-inducedCH4emissions(van Groenigen et al.,2013)and contributes~2.40%to the enhanced global warming effect(Zhang et al.,2022).The global warming potential of GHGs emissions from rice systems is roughly four times higher than either wheat or maize(Linquist et al.,2012). | Hui Xia Xianxian Zhang Yi Liu Junguo Bi Xiaosong Ma Anning Zhang Hongyan Liu Liang Chen Sheng Zhou Huan Gao Kai Xu Haibin Wei Guolan Liu Feiming Wang Hongyang Zhao Xingxing Luo Danping Hou Qiaojun Lou Fangjun Feng Liguo Zhou Shoujun Chen Ming Yan Tianfei Li Mingshou Li LeiWang Zaochang Liu Xinqiao Yu HanweiMei Lijun Luo | 2022 | Molecular Plant2022,15,9: | 3 |
| 4 | Collaborative visual SLAM for multiple agents:A brief survey显示文摘This article presents a brief survey to visual simultaneous localization and mapping (SLAM) systems applied to multiple independently moving agents, such as a team of ground or aerial vehicles, a group of users holding augmented or virtual reality devices. Such visual SLAM system, name as collaborative visual SLAM, is different from a typical visual SLAM deployed on a single agent in that information is exchanged or shared among different agents to achieve better robustness, efficiency, and accuracy. We review the representative works on this topic proposed in the past ten years and describe the key components involved in designing such a system including collaborative pose estimation and mapping tasks, as well as the emerging topic of decentralized architecture. We believe this brief survey could be helpful to someone who are working on this topic or developing multi-agent applications, particularly micro-aerial vehicle swarm or collaborative augmented/virtual reality. | Danping ZOU Ping TAN Wenxian YU | 2019 | Virtual Reality & Intelligent Hardware2019,1,5: | 1 |
| 5 | A Modified Evisceration Technique with Scleral Quadrisection and Porous Polyethylene Implantation显示文摘 | Danping Huang Yangyang Yu Rong Lu Huasheng Yang Jianhao Cai | 2009 | American Journal of Ophthalmology2009,,5: | 1 |
| 6 | Enzymatic cascade systems for D-amino acid synthesis:progress and perspectives显示文摘D-amino acids,different from the ubiquitous L-amino acids,are recognized as the“unnatural”amino acids.The applications of D-amino acids have drawn increasing interest from researchers in recent years,and D-amino acids are widely used in various industries,including for food products,pharmaceuticals,and agricultural chemicals.Inspired by the prevalent appli-cations,many synthetic methods for D-amino acids have been developed,which are mainly divided into chemical synthetic methods and biosynthetic methods.Chemical synthesis of D-amino acids has a variety of disadvantages such as multiple reaction steps,low yields,low reaction rates,and difficulties in product extraction.Thus,biosynthetic methods utilizing enzymes are attracting increasing attention because they are more energy-saving and environmentally friendly compared to traditional chemical synthesis.Among all enzymatic methods,multi-enzymatic cascade catalytic methods have significant advantages,such as lower costs,no need for intermediate separation,and higher catalytic efficiency,which is ascribed to the spatial proximity of biocatalysts.In this review,advances in multi-enzyme cascade catalytic systems as well as chemo-enzymatic approaches to synthesize D-amino acids are discussed. | Anwen Fan Jiarui Li Yangqing Yu Danping Zhang Yao Nie Yan Xu | 2021 | Systems Microbiology and Biomanufacturing2021,1,4: | 1 |
| 7 | Phytosulfokine-α Promotes Root Growth by Repressing Expression of Pectin Methylesterase Inhibitor (PMEI) Genes in Medicago truncatula显示文摘Phytosulfokine-α(PSK-α),a sulfated pentapeptide with the sequence YIYTQ,is encoded by a small precursor gene family in Arabidopsis.PSK-αregulates multiple growth and developmental processes as a novel peptide hormone.Despite its importance,functions of PSK-αin M.truncatula growth remains unknown.In this study,we identified five genes to encode PSK-αprecursors in M.truncatula.All of these precursors possess conserved PSK-αsignature motif.Expression pattern analysis of these MtPSK genes revealed that each gene was expressed in a tissue-specific or ubiquitous pattern and three of them were remarkably expressed in root.Treatment of M.truncatula seedlings with synthetic PSK-αpeptide significantly promoted root elongation.In addition,expression analysis of downstream genes by RNA-seq and qRT-PCR assays suggested that PSK-αsignaling might regulate cell wall structure via PMEI-PME module to promote root cell growth.Taken together,our results shed light on the mechanism by which PSK-αpromotes root growth in M.truncatula,providing a new resource for improvement of root growth in agriculture. | Liangliang Yu Wenjun Zhou Danping Zhang Junhui Yan Li Luo | 2020 | Phyton-International Journal of Experimental Botany2020,89,4: | 1 |
| 8 | Characteristics of diffusion-tensor imaging for healthy adult rhesus monkey brains显示文摘Diffusion-tensor imaging can be used to observe the microstructure of brain tissue.Fractional anisotropy reflects the integrity of white matter fibers.Fractional anisotropy of a young adult brain is low in gray matter,high in white matter,and highest in the splenium of the corpus callosum.Thus,we selected the anterior and posterior limbs of the internal capsule,head of the caudate nucleus,semioval center,thalamus,and corpus callosum(splenium and genu)as regions of interest when using diffusion-tensor imaging to observe fractional anisotropy of major white matter fiber tracts and the deep gray matter of healthy rhesus monkeys aged 4–8 years.Results showed no laterality differences in fractional anisotropy values.Fractional anisotropy values were low in the head of caudate nucleus and thalamus in gray matter.Fractional anisotropy values were highest in the splenium of corpus callosum in the white matter,followed by genu of the corpus callosum and the posterior limb of the internal capsule.Fractional anisotropy values were lowest in the semioval center and posterior limb of internal capsule.These results suggest that fractional anisotropy values in major white matter fibers and the deep gray matter of 4–8-year-old rhesus monkeys are similar to those of healthy young people. | Xinxiang Zhao Jun Pu Yaodong Fan Xiaoqun Niu Danping Yu Yanglin Zhang | 2013 | Neural Regeneration Research2013,8,31: | 0 |
| 9 | Neuronal insulin receptor mediates a positive feedback regulation of insulin biosynthesis in Drosophila显示文摘Insulin signaling is vital for the development and growth of mammals,which also plays a prominent role in the regulation of metabolism,stress response,reproduction,and behaviors.Therefore,insulin signaling is under tight regulation at the levels of insulin biosynthesis,secretion,and post-secretion action(Melloul et al.,2002;Na€ssel et al.,2013).Drosophila insulin-like peptides(DILPs) | Jie Ye Danping Chen Yue Yu Liming Wang | 2017 | Journal of Genetics and Genomics2017,44,2: | 0 |
| 10 | Synthetic protease inhibitor-induced inclusions in PC12 cells Potential proteomic characterization of six subunits in the 26S proteasome显示文摘Proteasome dysfunction during dopaminergic degeneration induces proteolytic stress, and is a contributing factor for the onset and formation of Lewy bodies. Results from our previous studies showed that synthetic proteasome inhibitor-induced inclusions in PC12 cells contained six subunits in the 26S proteasome. In the present study, mass spectrometry analysis of single protein spots resolved by two-dimensional gel electrophoresis and identified by bioinformatic analysis of peptide mass fingerprint (PMF) data were performed to comprehensively characterize the proteomic profile of the proteasome subunits. Results showed that six subunits in the 26S proteasome were characterized through accurate assignment by PMF data-specific protein identification in protein databases. Additionally, identification of one of the proteasome subunits was further confirmed using a subunit-specific antibody against non-adenosine triphosphatase subunit 11 of the 19S regulatory particle. Results suggest that the potential proteomic profile of six subunits in the 26S proteasome could be established from proteasome inhibitor-induced inclusions in PC12 cells. | Mingxiu Tian Xing'an Li Yingjiu Zhang Yihong Hu Ming Chang Tao Liu Danping Wang Yu Zhang Linsen Hu | 2010 | Neural Regeneration Research2010,5,22: | 0 |