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| 1 | Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails显示文摘 | Yanbin Fu Chenwen Huang Xinxiu Xu Haifeng Gu Youqiong Ye Cizhong Jiang Zilong Qiu Xin Xie | 2015 | Cell Research2015，25，9： | 24 |
| 2 | Dietary supplementation with Clostridium butyricum improves growth performance of broilers by regulating intestinal microbiota and mucosal epithelial cells显示文摘Clostridium butyricum has been widely considered an antibiotic substitute in recent years.It can promote growth performance,improve the immune response and enhance the intestinal barrier function of the host.In the present study,1-d-old Arbor Acres(AA)broilers were fed C.butyricum(1×109 cfu/kg)for 28 d.The transcriptomic characteristics of epithelial cells of the cecal mucosa were determined by RNA-sequence,and the cecal microbiota composition was explored by 16 S ribosomal RNA gene sequencing.The changes in the intestinal mucosa of broilers were then analyzed by tissue staining.Gene Ontology(GO)annotations identified substance transport and processes and pathways that might participate in intestinal development and cell viability.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis revealed that the differentially expressed genes are involved in numerous pathways related to amino acid and vitamin metabolism and antioxidant and defensive functions,among others.The relative expression of some genes associated with intestinal barrier function(claudins 2,15,19,and 23,tight junction proteins 1,2,and 3 and mucin 1)was significantly increased in the treatment group(P<0.05 or P<0.01).Moreover,the proportion of Firmicutes was higher in the C.butyricum-treated group,whereas the proportion of Proteobacteria was higher in the control group.At the genus level,the relative abundances of Butyricicoccus and Lactobacillus,among other bacteria,were increased after C.butyricum supplementation.The tissue staining analysis showed that the cecal mucosa of broilers was significantly ameliorated after the addition of C.butyricum(P<0.05 or P<0.01).These results showed that dietary supplementation with C.butyricum can enhance the antioxidant capacity,mucosal barrier function,and stabilize the cecal microbiota,resulting in improving the growth performance. | Laipeng Xu Xiangli Sun Xianhua Wan Keke Li Fuchun Jian Wenting Li Ruirui Jiang Ruili Han Hong Li Xiangtao Kang Yanbin Wang | 2021 | Animal Nutrition2021，，4： | 12 |
| 3 | Advances in fabrication of ceramic corundum abrasives based on sol–gel process显示文摘Corundum abrasives with good chemical stability can be fabricated into various free abrasives and bonded abrasive tools that are widely used in the precision machining of various parts.However,these abrasives cannot satisfy the machining requirements of difficult-to-machine materials with high hardness,high strength,and strong wearing resistance.Although superhard abrasives can machine the above-mentioned materials,their dressing and manufacturing costs are high.By contrast,ceramic corundum abrasives fabricated by sol–gel method is a costeffective product between conventional and superhard abrasives.Ceramic corundum abrasives exhibit self-sharpening and high toughness.In this review,the optimization methods of ceramic corundum abrasive properties are introduced from three aspects:precursor synthesis,particle shaping,and sintering.Firstly,the functional mechanism of seeds and additives on the microstructural and mechanical properties of abrasives is analyzed.Specifically,seeds can reduce the phase transition temperature and improve fracture toughness.The grain size and uniformly dense structure can be controlled by applying an appropriate amount of multicomponent additives.Then,the urgent need of engineering application and machinability of special shape ceramic corundum abrasives is reviewed,and three methods of abrasive shaping are summarized.The micromold replication technique is highly advanced and can be used to prepare functional abrasives.Additionally,the influence of a new sintering method,namely,two-step sintering technique,on the microstructural and mechanical performance of ceramic corundum abrasives is summarized.Finally,the challenge and developmental trend of the optimization of ceramic corundum abrasives are prospected. | Baoteng HUANG Changhe LI Yanbin ZHANG Wenfeng DING Min YANG Yuying YANG Han ZHAI Xuefeng XU Dazhong WANG Sujan DEBNATH Muhammad JAMIL Hao Nan Li Hafiz Muhammad ALI Munish Kumar GUPTA Zafar SAID | 2021 | Chinese Journal of Aeronautics2021，34，6： | 11 |
| 4 | Milling surface roughness for 7050 aluminum alloy cavity influenced by nozzle position of nanofluid minimum quantity lubrication显示文摘In nanofluid minimum quantity lubrication(NMQL)milling of aviation aluminum alloy,it is the bottleneck problem to adjust the position parameters(target distance,incidence angle,and elevation angle)of the nozzle to improve the surface roughness of milling,which has large and uncontrollable errors.In this paper,the influence law of milling cutter speed,helical angle,and cavity shape on the flow field around the milling cutter was studied,and the optimal nozzle profile parameters were obtained.Using 7050 aluminum alloy as the workpiece material,the milling experiment of the NMQL cavity was conducted by utilizing cottonseed oil-based Al2 O3 nanofluid.Results show that the high velocity of the surrounding air flow field and the strong gas barrier could be attributed to high rotating velocities of the milling cutter.The incidence angle of the nozzle was consistent with the helical angle of the milling cutter,the target distance was appropriate at 25–30 mm,and the elevation angle was suitable at 60°–65°.The range and variance analyses of the signal-to-noise ratio of milling force and roughness were performed,and the chip morphology was observed and analyzed.The results show that the optimal combination of nozzle position parameters was the target distance of 30 mm,the incidence angle of 35°,and the elevation angle of 60°.Among these parameters,target distance had the largest impact on cutting performance with a contribution rate of more than 55%,followed by incidence angle and elevation contribution rate.Analysis by orthogonal experiment revealed that the nozzle position parameters were appropriate,and Ra(0.087 lm)was reduced by 30.4%from the maximum value(0.125 lm).Moreover,Rsm(0.05 mm)was minimum,which was 36%lower than that of the seventh group(Rsm=0.078 mm). | Zhenjing DUAN Changhe LI Yanbin ZHANG Lan DONG Xiufang BAI Min YANG Dongzhou JIA Runze LI Huajun CAO Xuefeng XU | 2021 | Chinese Journal of Aeronautics2021，34，6： | 10 |
| 5 | Sporopollen Assemblages from the Cretaceous Yimin Formation of the Hailar Basin,Inner Mongolia,China显示文摘Three sporopollen assemblages are recognized for the first time from the Cretaceous Yimin Formation in the Hailar Basin of eastern Inner Mongolia. They are (in ascending order): the Impardecispora-Aequitriradites-Clavatipollenites assemblage; the Triporoletes-Pilosisporites-Asteropollis assemblage; and the Appendicisporites-Asteropollis-Tricolpites assemblage, distributed in Members 1, 2 and 3 of the Yimin Formation respectively. Recognition of this biostratigraphic sequence is very important for the division and correlation of the Yimin Formation in the basin. Meanwhile, the age of the Yimin Formation is considered to be Barremian to Early Albian based on the palynological data. | WAN Chuanbiao QIAO Xiuyun XU Yanbin SUN Yuewu REN Yanguang JIN Yudong GAO Ping LIU Tongyan | 2005 | Acta Geologica Sinica(English Edition)2005，79，4： | 9 |
| 6 | Hierarchical Co3O4 porous nanowires as an efficient bifunctional cathode catalyst for long life Li-O2 batteries显示文摘层次公司 < 潜水艇 class= “ a-plus-plus ” > 3 O < 潜水艇 class= “ a-plus-plus ” > 4 多孔的 nanowires (NW ) 用锻烧跟随的一个热水的方法被综合了。当在非水的Li氧电池作为阴极催化剂采用了时,公司<潜水艇class=“ a-plus-plus ”> 3 O <潜水艇class=“ a-plus-plus ”> 4 NW 有效地两个都改进双程的效率和骑车的稳定性,它能被归因于公司的高催化的活动<潜水艇class=“ a-plus-plus ”> 3 O <潜水艇class=“ a-plus-plus ”>为氧减小反应和氧进化反应的 4 NW 分别地在分泌物和费用期间处理。 | Qingchao Liu Yinshan Jiang Jijing Xu Dan Xu Zhiwen Chang Yanbin Yin Wanqiang Liu Xinbo Zhang | 2015 | Nano Research2015，8，2： | 9 |
| 7 | Cryogenic minimum quantity lubrication machining: from mechanism to application显示文摘Cutting fluid plays a cooling-lubrication role in the cutting of metal materials.However,the substantial usage of cutting fluid in traditional flood machining seriously pollutes the environment and threatens the health of workers.Environmental machining technologies,such as dry cutting,minimum quantity lubrication(MQL),and cryogenic cooling technology,have been used as substitute for flood machining.However,the insufficient cooling capacity of MQL with normal-temperature compressed gas and the lack of lubricating performance of cryogenic cooling technology limit their industrial application.The technical bottleneck of mechanical-thermal damage of difficult-to-cut materials in aerospace and other fields can be solved by combining cryogenic medium and MQL.The latest progress of cryogenic minimum quantity lubrication(CMQL)technology is reviewed in this paper,and the key scientific issues in the research achievements of CMQL are clarified.First,the application forms and process characteristics of CMQL devices in turning,milling,and grinding are systematically summarized from traditional settings to innovative design.Second,the cooling-lubrication mechanism of CMQL and its influence mechanism on material hardness,cutting force,tool wear,and workpiece surface quality in cutting are extensively revealed.The effects of CMQL are systematically analyzed based on its mechanism and application form.Results show that the application effect of CMQL is better than that of cryogenic technology or MQL alone.Finally,the prospect,which provides basis and support for engineering application and development of CMQL technology,is introduced considering the limitations of CMQL. | Mingzheng LIU Changhe LI Yanbin ZHANG Qinglong AN Min YANG Teng GAO Cong MAO Bo LIU Huajun CAO Xuefeng XU Zafar SAID Sujan DEBNATH Muhammad JAMIL Hafz Muhammad ALI Shubham SHARMA | 2021 | Frontiers of Mechanical Engineering2021，16，4： | 8 |
| 8 | Blocking autocrine VEGF signaling by sunitinib, an anti-cancer drug, promotes embryonic stem cell selfrenewal and somatic cell reprogramming显示文摘 | Guofang Chen Xinxiu Xu Lihong Zhang Yanbin Fu Min Wang Haifeng Gu Xin Xie | 2014 | Cell Research2014，24，9： | 8 |
| 9 | Characterization and pilot scale test of a fluidized bed two-stage gasification process for the production of clean industrial fuel gas from low-rank coal显示文摘To utilize low rank coal efficiently,a fluidized bed two-stage(FBTS)gasification process,mainly consisting of a FB pyrolyzer and a transport FB(TFB)gasifier,has been proposed for the production of clean fuel gas.To verify the feasibility and technical features of this novel gasification technology,a pilot autothermal platform,with a treating capacity of 100 kg/h for coal,was designed and built up.By adopting a kind of lignite from Inner Mongolia,the running state and fuel gas quality were compared systematically under typical operational conditions.The results show that by keeping the reaction temperatures of pyrolyzer and gasifier at around 840C and 1000C,respectively,the corresponding tar content in fuel gas at the outlets of pyrolyzer and gasifier were 1127 mg/Nm3 and 365 mg/Nm3,reaching a high tar removal efficiency.Under the stable operation state,the volume fractions of CO,H2,CH4 and CO2 in fuel gas were 14.4%,8.3%,3.4%and 11.3%,respectively,and the corresponding higher heating value of fuel gas was about 1100 kcal/Nm3.Compared with the tar from pyrolyzer,the heavy oil fraction in tar from gasifier reduced significantly,while the light oil components increased sharply simultaneously,showing significant effect of catalytic reforming by hot char bed on tar removal. | Xi Zeng Fang Wang Zhennan Han Yanlin Sun Yanbin Cui Guangwen Xu | 2018 | Carbon Resources Conversion2018，1，1： | 8 |
| 10 | Milling Force Model for Aviation Aluminum Alloy: Academic Insight and Perspective Analysis显示文摘Aluminum alloy is the main structural material of aircraft,launch vehicle,spaceship,and space station and is processed by milling.However,tool wear and vibration are the bottlenecks in the milling process of aviation aluminum alloy.The machining accuracy and surface quality of aluminum alloy milling depend on the cutting parameters,material mechanical properties,machine tools,and other parameters.In particular,milling force is the crucial factor to determine material removal and workpiece surface integrity.However,establishing the prediction model of milling force is important and difficult because milling force is the result of multiparameter coupling of process system.The research progress of cutting force model is reviewed from three modeling methods:empirical model,finite element simulation,and instantaneous milling force model.The problems of cutting force modeling are also determined.In view of these problems,the future work direction is proposed in the following four aspects:(1)high-speed milling is adopted for the thin-walled structure of large aviation with large cutting depth,which easily produces high residual stress.The residual stress should be analyzed under this particular condition.(2)Multiple factors(e.g.,eccentric swing milling parameters,lubrication conditions,tools,tool and workpiece deformation,and size effect)should be considered comprehensively when modeling instantaneous milling forces,especially for micro milling and complex surface machining.(3)The database of milling force model,including the corresponding workpiece materials,working condition,cutting tools(geometric figures and coatings),and other parameters,should be established.(4)The effect of chatter on the prediction accuracy of milling force cannot be ignored in thin-walled workpiece milling.(5)The cutting force of aviation aluminum alloy milling under the condition of minimum quantity lubrication(mql)and nanofluid mql should be predicted. | Zhenjing Duan Changhe Li Wenfeng Ding Yanbin Zhang Min Yang Teng Gao Huajun Cao Xuefeng Xu Dazhong Wang Cong Mao Hao Nan Li Gupta Munish Kumar Zafar Said Sujan Debnath Muhammad Jamil Hafiz Muhammad Ali | 2021 | Chinese Journal of Mechanical Engineering2021，34，1： | 7 |
| 11 | Two Poplar Glycosyltransferase Genes, PdGATL 1.1 and PdGATL1.2, Are Functional Orthologs to PARVUS/AtGATL 1 in Arabidopsis显示文摘包括 PARVUS/AtGATL1,在 Arabidopsis 的几基因在木聚糖合成被含有。然而,在这多糖是木头的一个主要部件的地方,在木质的植物的木聚糖的生合成糟糕被理解。这里,我们描绘二 Populus 基因, PdGATL1.1 和 PdGATL1.2,最靠近的 orthologs 到 Arabidopsis PARVUS/GATL1 基因关于他们在白杨的基因表示,他们在 Arabidopsis 补充 parvus 变化的亚 cellular 本地化,和他们的能力。包括词法变化,在缺点的救的大多数由 parvus 变化引起了的 parvus 异种的二白杨基因的 Overexpression 折叠木部,并且改变了房间墙 monosaccharide 作文。量的 RTPCR 证明 PdGATL1.1 在开发白杨的木部最强烈被表示。相反, PdGATL1.2 在叶,射击尖端,外皮,韧皮部,和木部更一致地被表示,并且 PdGATL1.2 的抄本水平是比在检验的所有纸巾的 PdGATL1.1 的低得多的。亚 cellular 本地化实验证明这二蛋白质对局部性嗯并且与到这些亚 cellular 分隔空间的标记蛋白质居民比较的 Golgi。我们的数据显示 PdGATL1.1 和 PdGATL1.2 是 PARVUS/GATL1 的功能的 orthologs 并且能在木聚糖合成起一个作用,但是可以也在另外的墙聚合物的合成有角色。 | Yingzhen Kong Gongke Zhou Utku Avci Xiaogang Gu Chelsea Jones Yanbin Yin Ying Xu Michael G. Hahn | 2009 | Molecular Plant2009，2，5： | 6 |
| 12 | Millisecond synthesis of CoS nanopartides for highly efficient overall water splitting显示文摘High performance and low-cost electrocatalysts for overall water splitting,i.e.,catalyzing hydrogen and oxygen evolution reactions with the same material,are of great importance for large-scale,renewable energy conversion processes.Here,we report an ultrafast(~7 ms)synthesis tech nique for tran sition metal chalcoge nide n anoparticles assisted by high temperature treatme nt.As a proof of con cept,we dem on strate that cobalt sulfide(~20 nm in diameter)@few-layer graphe ne(~2 nm in thick ness)core-shell nan oparticles embedded in RGO nano sheets exhibit remarkable bifunctional electrocatalytic activity and stability for overall water splitting,which is comparable to commercial 40 wt.%platinum/carbon(Pt/C)electrocatalysts.After 60 h of continuous operation,10 mA crrT?water splitting current density can still be achieved at a low potential of^1.77 V without any activity decay,which is among the most active for non-noble material based electrocatalysts.The presented study provides prospects in synthesizing highly efficient bifunctional electrocatalysts for large-scale energy conversion application via a simple yet efficient technique. | Yanan Chen Shaomao Xu Shuze Zhu Rohit Jiji Jacob Glenn Pastel Yanbin Wang Yiju Li Jiaqi Dai Fengjuan Chen Hua Xie Boyang Liu Yonggang Yao Lourdes G. Salamanca-Riba Michael R. Zachariah Teng Li Liangbing Hu | 2019 | Nano Research2019，12，9： | 6 |
| 13 | Nano-enhanced biolubricant in sustainable manufacturing:From processability to mechanisms显示文摘To eliminate the negative effect of traditional metal-working fluids and achieve sustainable manufacturing,the usage of nano-enhanced biolubricant(NEBL)is widely researched in minimum quantify lubrication(MQL)machining.It's improved tool wear and surface integrity have been preliminarily verified by experimental studies.The previous review papers also concluded the major influencing factors of processability including nano-enhancer and lubricant types,NEBL concentration,micro droplet size,and so on.Nevertheless,the complex action of NEBL,from preparation,atomization,infiltration to heat transfer and anti-friction,is indistinct which limits preparation of process specifications and popularity in factories.Especially in the complex machining process,in-depth understanding is difficult and meaningful.To fll this gap,this paper concentrates on the comprehensive quantitative assessment of processability based on tribological,thermal,and machined surface quality aspects for NEBL application in turning,milling,and grinding.Then it attempts to answer mechanisms systematically considering multi-factor influence of molecular structure,physicochemical properties,concentration,and dispersion.Firstly,this paper reveals advanced lubrication and heat transfer mechanisms of NEBL by quantitative comparison with biolubricant-based MQL machining.Secondly,the distinctive filmformation,atomization,and infiltration mechanisms of NEBL,as distinguished from metal-working fluid,are clarified combining with its unique molecular structure and physical properties.Furtherly,the process optimization strategy is concluded based on the synergistic relationship analysis among process variables,physicochemical properties,machining mechanisms,and performance of NEBL.Finally,the future development directions are put forward aiming at current performance limitations of NEBL,which requires improvement on preparation and jet methods respects.This paper will help scientists deeply understand effective mechanism,formulate process specifications,and find future development trend of this technology. | Yanbin ZHANG Hao Nan LI Changhe LI Chuanzhen HUANG Hafiz Muhammad ALI Xuefeng XU Cong MAO Wenfeng DING Xin CUI Min YANG Tianbiao YU Muhammad JAMIL Munish Kumar GUPTA Dongzhou JIA Zafar SAID | 2022 | Friction2022，10，6： | 5 |
| 14 | Analysis of grinding mechanics and improved grinding force model based on randomized grain geometric characteristics显示文摘Too high grinding force will lead to a large increase in specific grinding energy, resulting in high temperature in grinding zone, especially for the aerospace difficult cutting metal materials,seriously affecting the surface quality and accuracy. At present, the theoretical models of grinding force are mostly based on the assumption of uniform or simplified morphological characteristics of grains, which is inconsistent with the actual grains. Especially for non-engineering grinding wheel,most geometric characteristics of grains are ignored, resulting in the calculation accuracy that cannot guide practical production. Based on this, an improved grinding force model based on random grain geometric characteristics is proposed in this paper. Firstly, the surface topography model of CBN grinding wheel is established, and the effective grain determination mechanism in grinding zone is revealed. Based on the known grinding force model and mechanical behavior of interaction between grains and workpiece in different stages, the concept of grain effective action area is proposed. The variation mechanism of effective action area under the influence of grain geometric and spatial characteristics is deeply analyzed, and the calculation method under random combination of five influencing parameters is obtained. The numerical simulation is carried out to reveal the dynamic variation process of grinding force in grinding zone. In order to verify the theoretical model, the experiments of dry grinding Ti-6Al-4 V are designed. The experimental results show that under different machining parameters, the results of numerical calculation and experimental measurement are in good agreement, and the minimum error value is only 2.1 %, which indicates that the calculation accuracy of grinding force model meets the requirements and is feasible. This study will provide a theoretical basis for optimizing the wheel structure, effectively controlling the grinding force range, adjusting the grinding zone temperature and improving the workpiece machining quality in the industrial grinding process. | Mingzheng LIU Changhe LI Yanbin ZHANG Min YANG Teng GAO Xin CUI Xiaoming WANG Wenhao XU Zongming ZHOU Bo LIU Zafar SAID Runze LI Shubham SHARMA | 2023 | Chinese Journal of Aeronautics2023，36，7： | 5 |
| 15 | Electrostatic atomization minimum quantity lubrication machining:from mechanism to application显示文摘Metal cutting fluids(MCFs)under flood conditions do not meet the urgent needs of reducing carbon emission.Biolubricant-based minimum quantity lubrication(MQL)is an effective alternative to flood lubrication.However,pneumatic atomization MQL has poor atomization properties,which is detrimental to occupational health.Therefore,electrostatic atomization MQL requires preliminary exploratory studies.However,systematic reviews are lacking in terms of capturing the current research status and development direction of this technology.This study aims to provide a comprehensive review and critical assessment of the existing understanding of electrostatic atomization MQL.This research can be used by scientists to gain insights into the action mechanism,theoretical basis,machining performance,and development direction of this technology.First,the critical equipment,eco-friendly atomization media(biolubricants),and empowering mechanisms of electrostatic atomization MQL are presented.Second,the advanced lubrication and heat transfer mechanisms of biolubricants are revealed by quantitatively comparing MQL with MCF-based wet machining.Third,the distinctive wetting and infiltration mechanisms of electrostatic atomization MQL,combined with its unique empowering mechanism and atomization method,are compared with those of pneumatic atomization MQL.Previous experiments have shown that electrostatic atomization MQL can reduce tool wear by 42.4%in metal cutting and improve the machined surface Ra by 47%compared with pneumatic atomization MQL.Finally,future development directions,including the improvement of the coordination parameters and equipment integration aspects,are proposed. | Wenhao Xu Changhe Li Yanbin Zhang Hafiz Muhammad Ali Shubham Sharma Runze Li Min Yang Teng Gao Mingzheng Liu Xiaoming Wang Zafar Said Xin Liu Zongming Zhou | 2022 | International Journal of Extreme Manufacturing2022，4，4： | 4 |
| 16 | Effect of ZRB 2-modified on microstructure and mechanical properties of Mg-Zn-Y-Mn alloy显示文摘The ZrB 2 particles firstly modified Mg_(94)Zn_(2.5)Y_(2.5)Mn 1 alloy.And the microstructures and mechanical performances of the modified alloys were studied systematically.The results showed that the moderate addition of ZrB 2 accelerated the development of long-period stacking ordered(LPSO)structure and refined the grain size.The grains in ZrB 2-modified alloys were nearly equiaxed with a homogeneous size.When 0.0075 wt%ZrB 2 was added,the as-cast alloy with the finest grains(24.87μm)presented desirable mechanical properties(especially ductility)with maximum tensile strength and ductility of 225 MPa and 17.5%,respectively. | Zhe Zhang Yatong Zhang Jinshan Zhang Yi Li Yanbin Ma Chunxiang Xu | 2018 | Journal of Magnesium and Alloys2018，6，3： | 4 |
| 17 | Minimum quantity lubrication machining of aeronautical materials using carbon group nanolubricant: From mechanisms to application显示文摘It is an inevitable trend of sustainable manufacturing to replace flood and dry machining with minimum quantity lubrication(MQL)technology.Nevertheless,for aeronautical difficult-tomachine materials,MQL couldn’t meet the high demand of cooling and lubrication due to high heat generation during machining.Nano-biolubricants,especially non-toxic carbon group nano-enhancers(CGNs)are used,can solve this technical bottleneck.However,the machining mechanisms under lubrication of CGNs are unclear at complex interface between tool and workpiece,which characterized by high temperature,pressure,and speed,limited its application in factories and necessitates in-depth understanding.To fill this gap,this study concentrates on the comprehensive quantitative assessment of tribological characteristics based on force,tool wear,chip,and surface integrity in titanium alloy and nickel alloy machining and attempts to answer mechanisms systematically.First,to establish evaluation standard,the cutting mechanisms and performance improvement behavior covering antifriction,antiwear,tool failure,material removal,and surface formation of MQL were revealed.Second,the unique film formation and lubrication behaviors of CGNs in MQL turning,milling,and grinding are concluded.The influence law of molecular structure and micromorphology of CGNs was also answered and optimized options were recommended by considering diverse boundary conditions.Finally,in view of CGNs limitations in MQL,the future development direction is proposed,which needs to be improved in thermal stability of lubricant,activity of CGNs,controllable atomization and transportation methods,and intelligent formation of processing technology solutions. | Xin CUI Changhe LI Wenfeng Ding Yun CHEN Cong MAO Xuefeng XU Bo LIU Dazhong WANG Hao Nan LI Yanbin ZHANG Zafar SAID Sujan DEBNATH Muhammad JAMIL Hafiz Muhammad ALI Shubham SHARMA | 2022 | Chinese Journal of Aeronautics2022，35，11： | 3 |
| 18 | Multi-locus association study of schizophrenia susceptibility genes with a posterior probability method显示文摘Schizophrenia is a serious neuropsychiatric illness affecting about 1% of the world’s population. It is considered a complex inheritance disorder. A number of genes are involved in combination in the etiology of the disorder. Evidence implicates the altered dopaminergic trans- mission in schizophrenia. In the present study, in order to identify susceptibility genes for schizophrenia in dopaminergic metabolism, we analyzed 59 single nucleotide polymorphisms (SNPs) in 24 genes of the dopaminergic pathway among 82 unrelated patients with schizophre- nia and 108 matched normal controls. Considering that traditional single-locus association stud- ies ignore the multigenic nature of complex diseases and do not take into account possible in- teractions between susceptibility genes, we proposed a multi-locus analysis method, using the posterior probability of morbidity as a measure of absolute disease risk for a multi-locus genotype combination, and developed an algorithm based on perturbation and average to detect the sus- ceptibility multi-locus genotype combinations, as well as to repress noise and avoid false positive results at our best. A three-locus SNP genotype combination involved in the interactions of COMT and ALDH3B1 genes was detected to be significantly susceptible to schizophrenia. | SUN Xiangqing 1* , JIA Yanbin 2* , ZHANG Xuegong 1 , XU Qi 2 , SHEN Yan 2 & LI Yanda 1 1. Ministry of Education (MOE) Key Laboratory of Bioinformatics at Tsinghua University Department of Automation, Tsinghua University, Beijing 100084, China 2. National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China | 2005 | Science China(Life Sciences)2005，48，3： | 2 |
| 19 | Pseudomonas mendocina LYX:A novel aerobic bacterium with advantage of removing nitrate high effectively by assimilation and dissimilation simultaneously显示文摘The problem of nitrate accumulation in aerobic tank and total nitrogen excessive discharge in effluent was very common in traditional livestock and poultry farming wastewater treatment systems owing to the lengthy process flow and low process control level.A strain LYX of aerobic bacterium was isolated from the activated sludge of a wastewater treatment system in a pig farm,which could remove nitrate effectively in aerobic tank and was identified Pseudomonas mendocina by 16S rRNA sequencing.Under the condition of nitrate as the sole nitrogen source,this strain removed over 90%of NO_(3)^(−)-N with an initial concentration of 110 mg/L under aerobic conditions within 48 hours.Among them,37.9%of NO_(3)^(−)-N was assimilated into Bio-N,about 51.9%was reduced to gaseous nitrogen and less than 0.5%of nitrogen was replaced by NO_(3)^(−)-N and NH_(4)^(+)-N,9.7%NO_(3)^(−)-N remained in the effluent at the end.At the same time,four key genes(napA,nirK,norB and nosZ)related to nitrate nitrogen removal were expressed during the denitrification process of P.mendocina LYX,in which the transcription level of the indicator genes of this aerobic denitrifying bacterium(napA)was the highest.In addition,it was found with the 15N tracer technique that inoculation of this strain on sludge increased the amount of nitrogen loss from 9.26 nmol N/(g·h)to 23.835 nmol N/(g·h).Therefore,P.medocina LYX is a potential bioagent for advanced nitrogen removal by assimilating and reducing nitrate simultaneously in aerobic tanks. | Yuxin Li Jiayin Ling Pengcheng Chen Jinliang Chen Ruizhi Dai Jinsong Liao Jiejing Yu Yanbin Xu | 2021 | Frontiers of Environmental Science & Engineering2021，15，4： | 2 |
| 20 | The nature of irreversible phase transformation propagation in nickel-rich layered cathode for lithium-ion batteries显示文摘Ni-rich layered cathode is regarded as one of the most promising candidates to achieve lithium-ion batteries (LIBs) with high energy density. However, due to the irreversible phase transformation (IPT) and its eventual propagation from surface to the bulk of the material, Ni-rich layered cathode typically suffers from severe capacity fading, structure failure, and thermal instability, which greatly hinders its mass adoption. Hence, achieving an in-depth understanding of the IPT propagation mechanism in Ni-rich layered cathode is crucial in addressing these issues. Herein, the triggering factor of IPT propagation in Ni-rich cathode is verified to be the initial surface disordered cation mixing domain covered by a thin rock-salt phase, instead of the rock-salt phase itself. According to the density functional theory (DFT) results, it is further illustrated that the metastable cation mixing domain possesses a lower Ni migration energy barrier, which facilitates the migration of Ni ions towards the Li slab, and thus driving the propagation of IPT from surface to the bulk of the material. This finding clarifies a prevailing debate regarding the surface impurity phases of Ni-rich cathode material and reveals the origin of IPT propagation, which implies the principle and its effectiveness of tuning the surface microstructure to address the structural and thermal instability issue of Ni-rich layered cathode materials. | Feng Wu Na Liu Lai Chen Ning Li Jinyang Dong Yun Lu Guoqiang Tan Mingzhe Xu Duanyun Cao Yafei Liu Yanbin Chen Yuefeng Su | 2021 | Journal of Energy Chemistry2021，30，11： | 2 |
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