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| 1 | Advanced treatment of dyeing wastewater towards reuse by the combined Fenton oxidation and membrane bioreactor process显示文摘The performance of combined Fenton oxidation and membrane bioreactor (MBR) process for the advanced treatment of an effluent from an integrated dyeing wastewater treatment plant was evaluated. The experimental results revealed that under the optimum Fenton oxidation conditions (initial pH 5, H 2 O 2 dosage 17 mmol/L, and Fe 2+ 1.7 mmol/L) the average total organic carbon (TOC) and color removal ratios were 39.3% and 69.5% after 35 min of reaction, respectively. Results from Zahn-Wallens Test also represented that Fenton process was effective to enhance the biodegradability of the test wastewater. As for the further purification of MBR process, TOC removal capacity was examined at different hydraulic retention times (HRT) of 10, 18 and 25 hr. Under the optimum HRT of 18 hr, the average TOC concentration and color of the final MBR effluent were 16.8 mg/L and 2 dilution time, respectively. The sludge yield coefficient was 0.13 g MLSS/g TOC and TOC degradation rate was 0.078 kg TOC/(m 3 ·day). The final effluent of MBR can meet the reuse criteria of urban recycling water-water quality standard for miscellaneous water consumption GBT18920-2002. | Fei Feng Zhenliang XU Xiaohuan Li Wenting You Yang Zhen | 2010 | Journal of Environmental Sciences2010，22，11： | 27 |
| 2 | Thiolactone copolymer donor gifts organic solar cells a 16.72% efficiency显示文摘Since 1995,bulk-heterojunction organic solar cells consisting of one or two organic donors and one or two organic acceptors have been fighting for high power conversion efficiencies(PCEs)and good stability[1].Until recent years,this next-generation photovoltaic technology starts to offer decent PCEs,shedding the light on commercialization,and attracting great attention again[2-14].Compared w让h the continuously emerging highperformance nonfullerene acceptors,high-performance donors are rare. | Ji Xiong Ke Jin Yufan Jiang Jianqiang Qin Tan Wang Jinfeng Liu Qishi Liu Haili Peng Xiongfeng Li Anxin Sun Xianyi Meng Lixiu Zhang Ling Liu Wenting Li Zhimin Fang Xue Jia Zuo Xiao Yaqing Feng Xiaotao Zhang Kuan Sun Shangfeng Yang Shengwei Shi Liming Ding | 2019 | Science Bulletin2019，64，21： | 17 |
| 3 | Construction and genetic analysis of mutator insertion mutant population in maize显示文摘A total of 26718 M1 plants were ob- tained by crossing the active mutator transposon donor parents (Q105, WW51, 115F, V26-2 and 919J) with the recipient parents (Hz85,W328 with Bz gene and S-Mo17Rf3Rf3). The phenotypes of M1 plants were observed in the field. M1 plants were self-pollinated to develop the mutator insertion-mutagenized M2 seeds. The transposition frequency of the mutator in the genome was calculated based on the spotted aleurone phenotype of the M2 seeds. The results showed that: (1) the mutation frequency of M1 phe- notypes in the field was 0.07 in the population of W328×Mu; (2) the mutation frequency of spotted aleurone seeds on the M2 ears was 0.122 in the population of W328×Mu; (3) five S-cytoplasm male-sterile plants were found among 22500 M1 plants of S-Mo17Rf3Rf3×Mu, with the transposition frequency about 2.2×10?4 per locus. 99 flanking se- quences of mutator transposition were amplified by the modified MuTAIL-PCR, and 59 non-redundant sequences with length around 400 bp were obtained. After bioinformatic analysis, 27 sequences of them could be annotated, using non-redundant nucleotide database of maize, rice, and Arabidopsis. 36 se- quences of them were located on the genetic map of maize by comparative genomics, and several flank- ing sequences of mutator insertion were mapped on the single marker locus. Hotspot sequences of mu- tator transposition were revealed by comparing the homologies between the 9-bp target site duplication of the mutator insertion. The putative functions of 8 flanking sequences of mutator transposition had identity with the functions of their correspondingmarker. The constructed mutator insertion mutant population in maize will facilitate the new gene discovery and functional genomics study in maize. | LIU Wenting GAO Youjun TENG Feng SHI Qing ZHENG Yonglian | 2006 | Chinese Science Bulletin2006，51，21： | 4 |
| 4 | Evaluation of the immunomodulatory effects of anti-COVID-19 TCM formulae by multiple virus-related pathways显示文摘Dear Editor,The coronavirus infectious disease 2019(COVID-19)outbreak is seriously endangering human health.Most patients with severe COVID-19 are characterized by sustained cytokine production and hyper-inflammation,which is known as cytokine storm syndrome.1-3 Elaborating the anti-inflammatory response is crucial to these patients,and interieukin-6(IL6)inhibitors and steroids have been recommended in clinical practice.1 However,after the cytokine storm phase,the host immune response to sepsis may develop into a protracted immunosuppressive phase. | Liansheng Qiao Wenting Huang Xiaoling Zhang Hongyan Guo Dong Wang Quansheng Feng Ronghua Jin Lan Xie Weimin Li Jing Cheng | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 4 |
| 5 | Porcine skeletal muscle tissue fabrication for cultured meat production using three-dimensional bioprinting technology显示文摘Cultured meat produced through in vitro cell culture technology is regarded as a technical revolution.In this study,three-dimensional(3D)bioprinting technology was used to mimic the growth environment in vivo and construct a 3D culture system in vilro.Hydroge1 bioinks,namely,sodium alginate-gelatin and gelatin-methacrylate(GelMA)-silk fbroin,produced using two different curing processes were blended,and their rheological properties,mechanical properties,and biocompatibilities were compared.The 4%GelMA-20%silk fibroin hydroge1(GS2)demonstrated good performance and was hybridized with porcine skeleta1 muscle satellite cells for 3D printing to construct network structures of size 15 mm×15 mm and porosity 1000 um in 4-,6-,and 8-1ayer struchures.After 16 days of culture,4-and 6-1ayer grid structures formed compact muscle fbers organized by multinucleated myotubes.These results suggested that 3D bioprinting and GeIMA-silk fbroin hydrogels have great potential in fabricating porcine skeleta1 muscle tissue for use as cultured meat. | Yingying Li Wenting Liu Shilei Li Mingyue Zhang Feng Yang Shouwei Wang | 2021 | Journal of Future Foods2021，1，1： | 3 |
| 6 | Efficient production of pronuclear embryos in breeding and nonbreeding season for generating transgenic sheep overexpressing TLR4显示文摘Background: Brucella is a zoonotic Gram-negative pathogen that causes abortion and infertility in ruminants and humans. TLR4 is the receptor for LPS which can recognize Brucella and initiate antigen-presenting cell activities that affect both innate and adaptive immunity. Consequently, transgenic sheep over-expressing TLR4 are an suitable model to investigate the effects of TLR4 on preventing Brucellosis. In this study, we generated transgenic sheep overexpressing TLR4 and aimed to evaluate the effects of different seasons(breeding and non-breeding season) on superovulation and the imported exogenous gene on growth.Results: In total of 43 donor ewes and 166 recipient ewes in breeding season, 37 donor ewes and 144 recipient ewes in non-breeding season were selected for super-ovulation and injected embryo transfer to generate transgenic sheep.Our results indicated the no. of embryos recovered of donors and the rate of pronuclear embryos did not show any significant difference between breeding and non-breeding seasons(P > 0.05). The positive rate of exogenous TLR4 tested were 21.21 % and 22.58 % in breeding and non-breeding season by Southern blot. The expression level of TLR4 in the transgenic sheep was 1.5 times higher than in the non-transgenic group(P < 0.05). The lambs overexpressing TLR4 had similar growth performance with non-transgenic lambs, and the blood physiological parameters of transgenic and non-transgenic were both in the normal range and did not show any difference.Conclusions: Here we establish an efficient platform for the production of transgenic sheep by the microinjection of pronuclear embryos during the whole year. The over-expression of TLR4 had no adverse effect on the growth of the sheep. | Yan Li Di Lian Shoulong Deng Xiaosheng Zhang Jinlong Zhang Wenting Li Hai Bai Zhixian Wang Hongping Wu Juncai Fu Hongbing Han Jianzhong Feng Guoshi Liu Ling Lian Zhengxing Lian | 2017 | Journal of Animal Science and Biotechnology2017，8，1： | 2 |
| 7 | Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke显示文摘 | Jiayin Wang Yejie Shi Lili Zhang Feng Zhang Xiaoming Hu Wenting Zhang Rehana K. Leak Yanqin Gao Ling Chen Jun Chen | 2014 | Neurobiology of Disease2014，，： | 1 |
| 8 | Plant carbon inputs and environmental factors strongly affect soil respiration in a subtropical forest of southwestern China显示文摘 | Douglas A. Schaefer Wenting Feng Xiaoming Zou | 2008 | Soil Biology and Biochemistry2008，，5： | 1 |
| 9 | Notch Signaling Activation Promotes Seizure Activity in Temporal Lobe Epilepsy显示文摘 | Longze Sha Xiaofeng Wu Yuan Yao Bo Wen Jing Feng Zhiqiang Sha Xueqin Wang Xiaoliang Xing Wanchen Dou Liri Jin Wenting Li Naili Wang Yan Shen Jinhui Wang Liwen Wu Qi Xu | 2014 | Molecular Neurobiology2014，，2： | 1 |
| 10 | Coking behaviors and kinetics on HZSM-5/SAPO-34 catalysts for conversion of ethanol to propylene显示文摘The coke deposition on HZSM-5/SAPO-34 composite catalysts has been studied in the conversion of ethanol to propylene. The HZSM-5/SAPO-34 composite catalysts were synthesized by hydrothermal method(ZS-HS) and fully blending(ZS-MM). The used catalysts were characterized by XRD, N_2 adsorption–desorption, TGA, TPO, elemental analysis, FTIR and XPS. The coking kinetics on both ZS-HS and ZS-MM has been investigated and their coking rate equations were obtained. The used ZS-MM catalyst had higher amount of coke and lower nC:nHthan the used ZS-HS. 90% of the coke was deposited in the micropores of ZS-HS, while almost 45% of the coke located in the micropores of ZS-MM. The coke deposited on ZS-HS catalyst was mainly graphite-like carbon species, whereas dehydrogenated coke species was the major on ZS-MM. The coking activation energy of ZS-MM was lower than that of ZS-HS, and the coking rate on ZS-MM was faster than on ZS-HS. In addition, the regeneration of ZS-MM catalyst showed that it had a good hydrothermal stability. The differences on coking behaviors on the two catalysts were due to their different acidic properties and textures. | Ting Bai Xin Zhang Feng Wang Wenting Qu Xiling Liu Chao Duan | 2016 | Journal of Energy Chemistry2016，25，3： | 1 |
| 11 | PL1 fusion gene: a novel visual selectable marker gene that confers tolerance to multiple abiotic stresses in transgenic tomato显示文摘 | Feng Jin Shu Li Lijie Dang Wenting Chai Pengli Li Ning Wang | 2012 | Transgenic Research2012，，5： | 1 |
| 12 | Preparation of biomimetic gene hydrogel via polymerase chain reaction for cell-free protein expression显示文摘Deoxyribonucleic acid(DNA)hydrogels,a three-dimensional(3 D)network made from DNA chains,have attracted great attention because of its molecular programmability,excellent biocompatibility and wide biomedical applications.Construction of hydrogel incorporating genetic function is still a challenge because of the limitations in available preparation methods.Herein,we develop a polymerase chain reaction(PCR)based strategy to construct gene integrated hydrogel to mimic the biofunction of nucleus zone.DNA primers were chemically modified by methacrylamide,which were used as modular primers in PCR to hybridize with template plasmid DNA,yielding methacrylamide functionalized gene(Acry-gene).Afterwards,Acry-gene was chemically cross-linked and compressed via free radical polymerization of terminal group methacrylamide to form a threedimensional gene network,namely gene hydrogel.The gene hydrogel retained the genetic function and expressed protein successfully in a cell free protein expression system.This work provides a general approach for the construction of biofunctional gene hydrogel which mimics bioprocesses,showing great potential in biomedicine and biomimetic fields. | Feng Li Wenting Yu Xue Zhang Xiaocui Guo Xihan Xu Xiaolei Sun Dayong Yang | 2020 | Science China Chemistry2020，63，1： | 1 |
| 13 | Chemical characteristics of fine particles during spring dust storm dominant period in two Chinese cities, Baotou and Wuwei显示文摘 | Min HU Fan YANG Dingli YUE Song GUO Mengting WEN Wenting ZHANG Feng TIAN | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 1 |
| 14 | Soil organic carbon saturation deficit under primary agricultural managements across major croplands in China显示文摘Introduction:To generate information for the effective management of soil organic carbon(SOC)sequestration in Chinese croplands,we compared the additional organic carbon(C)that can be stabilized by fine soil particles(<20μm)with typical fertilization practices across soil types and climate zones.Using data from 30 long-term experimental study sites across the major agricultural zones in China,we estimated stable SOC saturation deficit(SOC_(deficit))under no fertilization(CK),chemical fertilization(CF),straw plus CF(S+CF),and manure plus CF(M+CF).Stable SOC_(deficit)was defined as the difference between potential and current SOC stabilized by fine soil particles.Outcomes:Stable SOC_(deficit)values varied from 51%to 82%.Soils dominated by 2:1 clay minerals showed larger stable SOC_(deficit)than soils dominated by 1:1 clay minerals under each treatment.For soils dominated by 2:1 clay minerals,stable SOC_(deficit)was significantly lower under M+CF(69%)than under CK,CF,and S+CF(78-82%)treatments,and it increased with increasing mean annual temperature(<10°C).In soils dominated by 1:1 clay minerals,stable SOC_(deficit)was considerably lower in paddy and paddy-upland than in upland soils,suggesting that paddies effectively stabilize C inputs.Discussion:Agricultural soils in China have considerable C sequestration potential,despite decades of fertilization practices.To manage soil C sequestration and model soil C dynamics effectively,factors such as soil mineral types,fertilization,and cropland use should be considered.Conclusion:Our results demonstrated that manure addition was the best fertilization method for improving soil fertility,whereas straw return in Chinese croplands should take into account climate mitigation in future. | Jiaying Di Wenting Feng Wenju Zhang Andong Cai Minggang Xu | 2017 | Ecosystem Health and Sustainability2017，3，7： | 1 |
| 15 | Cerebral small vessel disease caused by PLOD3 mutation:Expanding the phenotypic spectrum of lysyl hydroxylase-3 deficiency显示文摘Introduction:Pathogenic variants inPLOD3,encoding lysyl hydroxylase-3(LH3),can cause a hereditary connective tissue disorder that has rarely been reported.It is a multi-system disease,presenting with craniofacial dysmorphisms,skeletal and eye manifestations,sensorineural hearing loss,and variable skin manifestations.Severe central nervous system involvement has not been reported.Case presentation:A 10-month-old girl was admitted with development delay and clustered epileptic spasms.Hypertelorism,an upturned nose,and low-set ears were noted in physical examination.Cerebral magnetic resonance imaging showed multiple intracranial malacias and bleeding foci,extensive abnormal signals in the white matter,and obvious brain atrophy,which was consistent with cerebral small vessel disease(SVD).Electroencephalography suggested hypsarrhythmia.The vertebrae were flattened.The distal end of the metacarpal bone in the left hand was irregular.She was diagnosed with West syndrome.Whole-exome sequencing revealed a novel homozygous variant of c.12161218delCTC(p.L406del)inPLOD3,which was found to be inherited from her heterozygous parents.Conclusion:We report a patient with pathogenicPLOD3 mutation who presented with cerebral SVD.This report expands the phenotypic spectrum of LH3 deficiency. | Ji Zhou Weixing Feng Xiuwei Zhuo Wenting Lu Junling Wang Fang Fang Xiaohui Wang | 2022 | Pediatric Investigation2022，6，3： | 0 |
| 16 | Bmi-1,a Polycomb Group Protein,Plays an Essential Role in Tumorigenesis and Metastasis显示文摘Dysregulation of polycomb group protein Bmi-1 expression has been linked with an invasive phenotype of certain human cancers and poor prognosis of patients; however, the underlying mechanisms are | Libing SONG Jun LI Wenting LIAO Yan FENG Wanli LIU Yixin ZENG Musheng ZENG | 2009 | 中国肺癌杂志2009，12，6： | 0 |
| 17 | A microexplosive shockwave-based drug delivery microsystem for treating hard-to-reach areas in the human body显示文摘Implantable drug-delivery microsystems have the capacity to locally meet therapeutic requirements by maximizing local drug efficacy and minimizing potential side effects.The internal organs of the human body including the esophagus,gastrointestinal tract,and respiratory tract,with anfractuos contours,all manifest with endoluminal lesions often located in a curved or zigzag area.The ability of localized drug delivery for these organs using existing therapeutic modalities is limited.Spraying a drug onto these areas and using the adhesion and water absorption properties of the drug powder to attach to lesion areas can provide effective treatment.This study aimed to report the development and application of microsystems based on microshockwave delivery of drugs.The devices comprised a warhead-like shell with a powder placed at the head of the device and a flexible rod that could be inserted at the tail.These devices had the capacity to deposit drugs on mucous membranes in curved or zigzag areas of organs in the body.The explosive impact characteristics of the device during drug delivery were analyzed by numerical simulation.In the experiment of drug delivery in pig intestines,we described the biosafety and drug delivery capacity of the system.We anticipate that such microsystems could be applied to a range of endoluminal diseases in curved or zigzag regions of the human body while maximizing the on-target effects of drugs. | Yi Sun Wenzhong Lou Hengzhen Feng Wenting Su Sining Lv | 2022 | Microsystems & Nanoengineering2022，8，5： | 0 |
| 18 | GmNMHC5 may promote nodulation via interaction with GmGAI in soybean显示文摘Soybean(Glycine max[L.]Merr.)is a food and oil crop whose growth and yield are influenced by root and nodule development.In the present study,Gm NMHC5 was found to promote the formation of nodules in overexpressing mutants.In contrast,the number of nodules in Gmnmhc5 edited with CRISPR/Cas9 decreased sharply.In 35 S:Gm NMHC5 mutants,expression levels of genes involved in nodulation were significantly up-regulated.Both in vitro and in vivo biochemical analyses showed that Gm NMHC5 directly interacted with Gm GAI(a DELLA protein),and the content of gibberellin 3(GA_(3))in overexpressing mutants was lower than that in the wild type.These results revealed that Gm NMHC5 participates in the classical GA signaling pathway,and may regulate the content of GA_3 to match the optimal concentration required for nodule formation,thereby promoting nodulation by directly interacting with Gm GAI.A model illustrating the mechanism by which Gm NMHC5 promotes soybean nodulation is presented. | Wenting Wang Zhili Wang Wensheng Hou Li Chen Bingjun Jiang Wenya Ma Lijuan Bai Wenwen Song Cailong Xu Tianfu Han Yongjun Feng Cunxiang Wu | 2022 | The Crop Journal2022，10，1： | 0 |
| 19 | Investigation on the short-term outcome and prognostic impact of predisposition,and precipitants in inpatients with chronic liver disease from Chinese AcuTe on CHronic LIver FailurE(CATCH-LIFE)cohorts显示文摘Aim:The study aimed to investigate the short-term outcomes of hospitalized patients with chronic liver disease(CLDs)and assess the prognostic impact of predisposition and precipitants,which currently remains unclear.Methods:The study included 3970 hospitalized patients with CLDs from two prospective longitudinal multicenter studies(NCT02457637 and NCT03641872)conducted in highly endemic hepatitis B virus(HBV)areas.Competing risk analysis was used to evaluate the effect of predispositions,including the etiology and severity of CLDs and precipitants;on sequential 28,90,and 365-day liver transplantation(LT)-free mortality.Results:Among all enrolled patients,76.8%of adverse outcomes(including death and LT)within one year occurred within 90 days.Compared with alcoholic etiology,the association of HBV etiology with poorer outcomes was remarkably on the 28th day(hazard ratio[HR],1.81;95%confidence interval[CI],1.07-3.06;p=0.026);however,and dimin-ished or became insignificant at 90 days and 365 days.Cirrhosis increased the adjusted risk for 365-day(HR,1.50;CI,1.13-1.99;p=0.004)LT-free mortality when compared with noncirrhosis.In patients with cirrhosis,prior decompensation(PD)independently increased the adjusted risk of 365-day LT-free mortality by 1.25-fold(p=0.021);however,it did not increase the risk for 90-day mortality.Neither the category nor the number of precipitants influenced the adjusted risk of 28 or 90-day LT-free mortality.Conclusions:The 90-day outcome should be considered a significant endpoint for evaluating the short-term prognosis of hospitalized patients with CLD.Predisposing factors,other than etiology,mainly affected the delayed(365-day)outcome.Timely effective therapy for CLD etiology,especially antiviral treatments for HBV,and post-discharge long-term surveillance monitoring in cirrhotic patients undergoing PD are suggested to enhance disease management and reduce mortality. | Yan Zhang Wenting Tan Xiaobo Wang Xin Zheng Yan Huang Beiling Li Zhongji Meng Yanhang Gao Zhiping Qian Feng Liu Xiaobo Lu Jia Shang Yubao Zheng Weituo Zhang Shan Yin Wenyi Gu Tongyu Wang Jianyi Wei Zixuan Shen Guohong Deng Yi Zhou Yixin Hou Qun Zhang Shue Xiong Jing Liu Liyuan Long Ruochan Chen Jinjun Chen Xiuhua Jiang Sen Luo Yuanyuan Chen Chang Jiang Jinming Zhao Liujuan Ji Xue Mei Jing Li Tao Li Rongjiong Zheng Xinyi Zhou Haotang Ren Yu Shi Hai Li for the CATCH‐LIFE Study Investigators of Chinese(Acute‐on)Chronic Liver Failure(CLIF)Consortium(Ch‐CLIFC) | 2023 | Portal Hypertension & Cirrhosis2023，2，3： | 0 |
| 20 | Microzone-explosion synthesis of porous carbon electrodes for advanced aqueous solid-state supercapacitors with a high-voltage gel electrolyte显示文摘A new microzone-combustion synthesis is proposed for preparing S, N-doped hierarchically porous carbons(CAC-CN) with a novel mixed microstructure of sp~2 short-range order area and sp~3 defective area,achieving a coexistence of high conductivity and high capacitance as well as good access for electrolyte.By engineering ‘‘water in salts' into a polymer matrix, a high-voltage(2.5 V) aqueous gel electrolyte(HGWIS) is prepared and used to construct an aqueous solid-state SCs by in situ polymerization between the electrodes. The good match of CAC-CN electrode and HG-WIS electrolyte endows the assembled devices with superior high energy density and excellent capacitance retention, also a good temperature robustness, as well a high flexibility in 0-180° bending cycles. This study indicates that the collaborative design strategy of electrode materials and electrolyte would be great potential in exploring advanced aqueous solid-state SCs. | Yongxu Du Wei Liu Yongpeng Cui Hongguang Fan Yuan Zhang Tianqi Wang Huanlei Wang Yongcheng Jin Shuang Liu Wenting Feng Ming Chen | 2021 | Journal of Energy Chemistry2021，30，9： | 0 |
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