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| 1 | Novel nutraceutic therapies for the treatment of metabolic syndrome显示文摘Nutraceutic therapies such as berberine, bitter melon,Gymnema sylvestre, Irvingia gabonensis, resveratrol and ursolic acid have been shown to help control metabolic syndrome(MetS). The effect of berberine on glucose and lipid metabolism, hypertension, obesity and MetS has been evaluated in animal models and humans. Most clinical trials involving bitter melon have been conducted to evaluate its effect on glucose metabolism; nevertheless, some studies have reported favorable effects on lipids and blood pressure although there is little information about its effect on body weight. Gymnema sylvestre helps to decrease body weight and blood sugar levels; however, there is limited information on dyslipidemia and hypertension. Clinical trials of Irvingia gabonensis have shown important effects decreasing glucose and cholesterol concentrations as well decreasing body weight. Resveratrol acts through different mechanisms to decrease blood pressure, lipids, glucose and weight, showing its effects on the population with Met S. Finally, there is evidence of positive effects with ursolic acid in in vitro and in vivo studies on glucose and lipid metabolism and on body weight and visceral fat. Therefore, a review of the beneficial effects and limitations of the above-mentioned nutraceutic therapies is presented. | Esperanza Martínez-Abundis Miriam Mendez-del Villar Karina G Pérez-Rubio Laura Y Zuniga Marisol Cortez-Navarrete Alejandra Ramírez-Rodriguez Manuel González-Ortiz | 2016 | World Journal of Diabetes2016，7，7： | 3 |
| 2 | Heart rate variability and cardiovascular mortality 显示文摘 | VILLAREAL R P LIU B C MASSUMI A | 2002 | Curr Atheroscler Rep2002，4，2： | 1 |
| 3 | New perspectives on nitrogen-fixing microorganisms in tropical and subtropical oceans显示文摘 | Zehr J P E J Carpenter and T A Villareal 2000 | 2000 | Trends in Microbiology2000，8，2： | 1 |
| 4 | TP53 R249S mutation, genetic variations in HBX and risk of hepatocellular carcinoma in The Gambia显示文摘 | Doriane A. Gouas Stéphanie Villar Sandra Ortiz-Cuaran Pénélope Legros Gilles Ferro Gregory D. Kirk Olufunmilayo A. Lesi Maimuna Mendy Ebrima Bah Marlin D. Friesen John Groopman Isabelle Chemin Pierre Hainaut | 2012 | Carcinogenesis2012，，6： | 1 |
| 5 | Cysticercosis of the central nervous system; clinical and therapeutic cosiderations 显示文摘 | Gonzalo Torrealba Del Villar S Tagle P | 1984 | J Neural Neurosurg Psychiattry1984，47，： | 1 |
| 6 | Antioxidant activity of different fractions of Spirulina platensis protein extract显示文摘 | Estrada P Bescos B P Villar del Fresno A M | 2001 | Farmaco2001，56，： | 1 |
| 7 | Generating the knowledge Base of a Fuzzy rule-based system by the genetic learning of the data base 显示文摘 | CORD(O)N O HERRERA F VILLAR P | 2001 | IEEE Trans on Fuzzy Systems2001，9，4： | 1 |
| 8 | 显示文摘 | WHITCOMBE M J RODRIGUEZ M E VILLAR P | 1995 | J Am Chem Soc1995，117，27： | 1 |
| 9 | On-farm monitoring of soil nitrate-nitrogen in irriga- ted cornfields in the Ebro Valley (Northeast Spain)显示文摘 | VILLAR MIR J M VILLAR-MIR P STOCKLE C O | 2002 | Agronomy Journal2002，18，： | 1 |
| 10 | Regularities in binary intermetallic compounds 显示文摘 | VILLARS P GIRGIS K | 1982 | Z Metallk1982，73，： | 1 |
| 11 | The role of thyroid hormones and prolactin in the control of fibre moult and associated changes in hair follicle activities in cashmere goats显示文摘 | Villar D McMillen S R Dicks P | | 0，，： | 1 |
| 12 | Optimization and validation of a new method of analysis for polycyclic aromatic hydrocarbons in sewage sludge by liquid chromatography after microwave assisted extraction 显示文摘 | Villar P Callej6n M Alonso E | 2004 | Anal Chim Acta2004，，524： | 1 |
| 13 | Obstructive sleep apnea syndrome, vascular pathology, endothelial function and endothelial ceils and circulating microparticles 显示文摘 | Stiefel P Sanchez-Armengol MA Villar J | 2013 | Arch Med Res2013，44，6： | 1 |
| 14 | The Linus Pauling File (LPF) and Its Application to Materials Design 显示文摘 | Villars P Onodera N Iwata S | 1998 | Journal of Alloys and Compounds1998，，279： | 1 |
| 15 | Waxy gene factor andresidual protein of rice starch granules 显示文摘 | VILLAREAL C P JULIANO B O | 1986 | Starch-StSrke1986，38，4： | 1 |
| 16 | Leaf morphology and leaf chemieal eomposition in three Quercus(Fagaceae) species along a rainfall gradient in NE Spain显示文摘 | Castro Diez P Villar Salvador P Perez Rontome C | 1997 | Trees1997，11，： | 1 |
| 17 | Stem xylem features in three Quercus (Fagaceae)specis along a climatic gradient in NE Spain 显示文摘 | Pedro Villar - Salvador Pilaf Castro - Díez Carmen Pérez -Rontomé | 1997 | Trees1997，12，2： | 1 |
| 18 | Effects of dry grinding on pyrophyllite 显示文摘 | Perez-Rodriguez J L Madrid Sanchez Del Villar L Sanchez Soto P J | 1988 | Clay Miner1988，23，4： | 1 |
| 19 | Soil compactioneffects on growth and root traits of tobacco depend onlight, water regime and mechanical stress显示文摘 | Alameda D Anten N P R Villar R | 2012 | SOIL &TILLAGE RESEARCH2012，120，： | 1 |
| 20 | Optimization and validation of a new method of analysis for polycyclic aromatic hydrocarbons in sewage sludge by liquid chromatography after microwave assisted extraction 显示文摘 | Villar P Callejon M Alonso E | 2004 | Analytica Chimica Acta2004，524，： | 1 |
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