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    题名 作者 年代 出处 被引量
12001~2010年体育改革与发展纲要显示文摘为实现我国的现代化建设目标 ,充分发挥体育在提高人民物质文化生活中的作用。国家体育总局经过充分调研 ,经过 1999年、2 0 0 0年全国体育工作会议修改 ,制定《2 0 0 1~ 2 0 10年体育改革与发展纲要》,纲要明确了 2 1世纪前10年我国体育的指导思想、基本战略和奋斗目标。提出 :10年内 ,大众体育普及程度明显提高 ,体育人口达总人口的40 %左右 ;竞技体育保持亚洲领先 ,夏季奥运会前列 ,实现冬季奥运会零的突破 ;体育产业初具规模等。《纲要》是我国体育今后The State Sport General Administration (December 15,2000) 2001体育科学2001,21,3:147
2Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis显示文摘AIM To observe the inhibition of antisenseoligonucleotides (asON) phosphorthioate to thetissue inhibitors metalloproteinase-1 (TIMP-1)gene and protein expression in the liver tissue ofimmunologically induced hepatic fibrosis rats.The possibility of reversing hepatic fibrosisthrough gene therapy was observed.METHODS Human serum albumin (HSA) wasused to attack rats, as hepatic fibrosis model, inwhich asONs were used to block the gene andprotein expressing TIMP-1. According to theanalysis of modulator, structure protein, codingseries of TIMP-1 genome, we designed fourdifferent asONs. These asONs were injected intothe hepatic fibrosis models through coccygealvein. The results was observed by RT-PCR formeasuring TIMP-1 mRNA expression,immunohistochemistry and in situ hybridizationfor collagen Ⅰ, Ⅲ, special staining of collagenfiber, and electron microscopic examination.RESULTS Hepatic fibrosis could last within 363days in our modified model. The expressinglevel of TIMP-1 was high during hepatic fibrosisprocess. It has been proved by theimmunohistochemical and the electronmicroscopic examination that the asONphosphorthioate of TIMP-1 could exactly expressin vivo. The effect of colchicine wasdemonstrated to inhibit the expressing level ofmRNA and the content of collagen Ⅰ, Ⅲ in theliver of experimental hepatic fibrosis rats.However, the electron microscopy research andthe pathologic grading of hepatic fibrosisshowed that there was no significant differencebetween the treatment group and the modelgroup (P>0.05).CONCLUSION The experimental rat model ofhepatic fibrosis is one of the preferable modelsto estimate the curative effect of anti-hepaticfibrosis drugs. The asON phosphorthioate ofTIMP-1 could block the gene and proteinexpression of TIMP-1 in the liver of experimentalhepatic fibrosis rats at the mRNA level. It ispossible to reverse hepatic fibrosis, and it isexpected to study a new drug of anti-hepaticfibrosis on the genetic level. Colchicine has verylimited therapeutic effect on hepatic fibrosis,furthermore, its toxicity and side effects areobvious.Qing He Nie Yong Qian Cheng Yu Mei Xie Yong Xing Zhou Yi Zhan Cao The Center of Infectious Disease Diagnosis and Treatment of PLA,Tangdu Hospital,Forth Military Medical University,Xi’an 710038,Shaanxi Province,ChinaDr,Qing He Nie graduated from Qinghai Medical College as a doctor in 1983,got master degree at Beijing 302 Army Hospital in 1993,got doctor degree at the Third Military Medical University in 1998,engaged in postdoctoral research at the Fourth Military Medical University from 1998 to 2000,now an associate professor,specialized in clinical and experimental research of infectious diseases,had more than 90 papers published,coauthor of ten books,first author of one book. 2001World Journal of Gastroenterology2001,7,3:73
3加入WTO的国有商业银行发展策略显示文摘随着加入WTO的日益临近 ,作为我国金融体系主体的国有商业银行 ,如何按有关制度和规则调整和改造现有管理体制和运行机制 ,是当前四大国有商业银行必须正视和亟待采取切实措施加以解决的重要课题。本文重点研究我国国有商业银行的发展问题 ,并提出进一步开放国有商业银行、提高其综合竞争力的基本思路和主要途径。山东省金融学会2000年课题组 王敏 刘薇 战庆欣 苑治亭 郑录军 2001金融研究2001,,2:13
4新疆尼勒克县加勒克斯卡茵特墓地发掘简报显示文摘加勒克斯卡茵特墓地位于伊犁河上游支流喀什河南岸一、二级台地上。该墓地绝大多数墓葬在封土堆下铺有一圈或两圈卵石,少数墓葬地上仅封有土堆,不铺卵石;墓室一般呈东西向,形制为竖穴土坑和竖穴偏室墓;葬式多为一次葬,少数为二次葬;随葬品均为生活用品和随身佩带的装饰品;墓葬年代集中在公元前5世纪至汉代。刘学堂 钱耀鹏 李溯源 于建军 周晓明 西北大学2000级部分考古专业学生 张玉芹 新华 吕恩国 2011考古与文物2011,,5:12
5Transretinoic acid inhibits rats gastric epithelial dysplasia induced by N-methyi-N-nitro-N-nitrosoguanidine:influences on cell apoptosis and expression of its regulatory genes显示文摘INTRODUCTIONGastric epithelial dysplasia (GED) hypothetically is a straight-forward concept: dysplastic epithelium replacing the normal gastric epithelium of the stomach [1].In the stomach ,like any other segment of the gut ,it is defined as an unequivocal non-invasive epithelial change[2,3].The observation of gastric dysplasia as a cancerous lesion was recognized over a century ago ,but it is only after the advent of gastroscopy that its clinical significance has been stressed[4-7].Ru Tao Cui~1 Gan Cai~2 Zhao Bao Yin~(2*) Yong Cheng~2 Qiu Hong Yang~1 Tao Tian~(3#) ~1Liver Center,Beijing Friendship Hospital Affiliated to CapitalUniversity of Medical Sciences~2Department of Gastroenterology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai China and Department of Pathophysiology.Shanghai Medical University.Shanghai,China ~3Pathological Department,Shanghai Medical University (?)Now working at UCLA,USA ~#Now working at University of Michigan,USADr.Ru Tao Cui graduated and got the bachelor degree from Shandong University of Traditional Chinese Medicine in 1994,got doctor degree from Shanghai University of Traditional Chinese Medicine in 2000,now studying as a postdoc,majoring gastroenterology,having 29 papers published. 2001World Journal of Gastroenterology2001,7,3:8
6大学生就业:挑战中的机遇显示文摘<2000年上海大学生发展研究>课题组 2001社会2001,21,9:6
7BASIC FLOW PATTERNS AND OPTIMUM HYDRAULIC DESIGN OF A SUCTION BOX OF PUMPING STATION显示文摘A numerical method based on 3 D turbulence flow was applied to simulate the flow pattern in suction boxes of six different types. In light of the computational results, the basic flow patterns in the boxes were revealed and a theoretical method to optimize hydraulically design of the suction box is developed. The box geometrical parameters, which influence the flow pattern in the box, could be optimized. The optimum criteria for the hydraulic design of the suction boxes of six types established, respectively. Furthermore, a summarization is given here based on the classification of the basic flow patterns in order to systematically understand the hydraulic design of suction boxes.Lu Lin guang Yangzhou University, Yangzhou 225009, P.R.China (Received April 14, 2000) 2000Journal of Hydrodynamics2000,12,4:6
8我国国民体质的地域特征及相关因素的分析显示文摘国家体育总局<2000年国民体质监测研究报告>课题组 2005体育科技文献通报2005,13,10:5
9Expression,purification and immunocharacteristics of recombination UreB protein of H.pylori显示文摘INTRODUCTIONHelicobacter pylori (H . pylori) is associated with the development of chronic gastritis ,peptic ulcer and gastric cancer and gastric MALT lymphoma[1-9],H .pylori has many antigens ,including urease ,heat shock protein and vacuolating cytotoxin and so on ,and urease is an important factor in the colinization of the gastric mucosa and suspected to cause damage to the gastric mucosa[10-14].At the same time ,urdase is also one of the important protective antigens .Chao Wu~1 Quan Ming Zou~1 Hong Guo~2 Xiao Peng Yuan~1 Wei Jun Zhang~1 Dong Shui Lu~1 Xu Hu Mao~1 ~1Department of Clinical Microbiology,Third Military Medical University,Chongqing 400038,China ~2Department of Gastroenterology,Xinqiao Hospital,Third Military Medical University,Chongqing 40003?,ChinaDr.Chao Wu graduated from Third Military Medical University as a postgraduate in 2000,now a lecturer,specialized in diagnosis,prevention and therapy of Helicobacter pylori infection,having 6 papers published. 2001World Journal of Gastroenterology2001,7,3:5
10黑龙江省2000年科技期刊发展规划及布局研究显示文摘研究、分析了黑龙江省科技期刊的现状和存在问题,阐述了运用系统动力学理论对黑龙江省产业结构预测分析,以及科技期刊结构与产业结构的关联性分析,提出了黑龙江省科技期刊的发展规划和政策建议。<黑龙江省2000年科技期刊发展规划及布局研究>课题组 1996中国科技期刊研究1996,7,1:5
11Neutron-induced apoptosis of HR8348 cells in vitro显示文摘INTRODUCTIONTo date ,the major therapy for rectal carcinoma is extensive abdomino-perineal resection[1]. Unfortunately ,after resection of rectal carcinoma ,many patients still die of blood-borne metastases ,usually in the liver or lungs ,or local prlvic recurrence[2,3],which is the major cause of morbidity and mortality in patients with rectal carcinoma .Pre-or postoperative radiotherapy can reduce the incidence of local rdcurrence[4-7].Li Ping Wang~1 Ke Liang~2 Yu Shen~2 Wei Bo Yin~2 G.Hans~3 Yan Jun Zeng~1 ~1Biomechanics & Medical Information Institute,Beijing Polytechnic University,Beijng 100022,China ~2Department of Gastrointestinal Surgery,Aalborg University,Denmark ~3Cancer Institute (Hospital),Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100021,ChinaLi Ping Wang graduated from Beijing Polytechnic University in 2000,major in tumor radiotherapy,having 3 papers published. 2001World Journal of Gastroenterology2001,7,3:5
12高职高专教育文化素质教育体系改革、建设的理论成果和实践经验显示文摘本文节选自教育部“新世纪高职高专教育人才培养模式和教学内容体系改革与建设项目计划”立项项目(编号工13-1)《高职高专教育文化素质教育体系改革、建设的研究与实践》的验收报告。它介绍了项目研究组所形成的8个理论成果和4条实践经验。教育部(2000)Ⅰ13-1课题组 2003常州工学院学报2003,16,4:4
13A Study on Super Speed Forming of Metal Sheet by Laser Shock Waves显示文摘Metal sheet plastic deformation or forming is gener at ed through a mechanical pressure or a thermal variation. These pressure variatio ns or thermal variations can be created by a variety of means such as press form ing, hydroforming, imploding detonation and so on. According to the magnitude of the strain rates all these forming methods can be divided into quasi-static fo rming and dynamical forming. Up to now there are no reports of forming methods w ith the strain rates above 10 5sec -1, even though the exploding forming. In this article, we work on a dynamic super-speed forming method driven by lase r shock waves and advanced a novel concept of laser shock forming. The initial o bservation of the laser shock forming is done through a bugle testing with speci mens of SUS430 sheet metal, using a neodymium-glass laser of pulse energy 10J~ 3 0J and duration of 20 ns (FWHM). The investigation revealed that the plastic de formation during the laser shock forming is characterized as ultrahigh strain ra te up to 10 7sec -1. We indicate that plastic deformation increases nonlin early when the energy density of the laser varies. By investigating the hardness and residual stress of the surfaces, we conclude that laser shock forming is a combination technique of laser shock strengthening and metal forming for introdu cing a strain harden and a compressive residual stress on the surface of the wor k-piece, and the treated surface by laser shock forming has good properties in fatigue and corrosion resistance. This technique can achieve forming wit h or without mould.ZHOU Jian-zhong 1, YANG Ji-chang 1, ZHANG Yong-kang 1, ZHOU Ming 2 (1. School of Mechanical Engineering, Jiangsu University, Zhenjiang, 21 2013 China 2. School of Material Science and Engineering, Jiangsu University, Zhenjiang 21 2000, China) 2002厦门大学学报(自然科学版)2002,41,S1:4
14中国国民体育锻炼现状分析显示文摘国际上将体力活动定义为:由骨骼肌收缩产生的身体活动,其可以在基础代谢的水平上,增加能量消耗。一般是将体力活动分为职业的、家庭的、休闲的和交通的体力活动。其中,休闲时间的体力活动可以进一步再分类,如比赛的体育项目、娱乐活动(如徒步旅行、骑脚踏车)和体育锻炼(exercise training)等。国家体育总局<2000年国民体质研究报告>课题组 王梅 张一民 江崇民 张景龙 2005体育科技文献通报2005,13,2:4
15Non-existence of positive radial solutions for a class of quasilinear elliptic system显示文摘In this paper, our main purpose is to establish some nonexistence results of positive radial solutions to the quasilinear ordinary differential equation system. The main results of the present paper are new and extend the previously known results.Zuodong YANG and Qishao LU (College of Science, Beijing University of Aeronautics and Astronautics, Beijing 100083, China) (Received October 8, 2000) 2000Communications in Nonlinear Science and Numerical Simulation2000,5,4:3
16Research on acoustic holography method for identification of sound sources显示文摘This paper presents the method named acoustic holography which can be used to identify noise sources. A new formula of holography reconstruction is obtained, based on the Kirchhoff integral formula. Some simulating tests are carried out using the new formula. The comparison with other reconstruction formulas proves that the new formula is more effective. By using acoustic holography method, some interesting results about the noise of a vehicle are shown. The results proves that acoustic holography is an effective method for the identification of the complex noise sources.YANG Diange ZHENG Sifa LI Yukang LIAN Xiaomin JIANG Xiaoyu(Automotive Engineering Department, Tsinghua University Beijing 100084)(State Key Laboratory of Automotive Safety and Energy Beijing 100084)Received Dec. 12, 2000 2002Chinese Journal of Acoustics2002,21,4:2
17Magnetic and Structural Properties in Co/Cu/Co Sandwiches with Ni and Cr Buffer Layers显示文摘The magnetic and structural properties in Co/Cu/Co sandwiches with Ni and Cr buffer layers were investigated. It was found that the coercivity in Ni layer buffered samples decreases with increasing Ni layer thickness, while that in Cr layer buffered ones increases with increasing Cr layer thickness, leading to a large difference in field sensitivity of their giant magnetoresistance (GMR) properties. X-ray diffraction and high resolution transmission electron microscope images exhibited that there is a strong fcc (111) texture in the samples with Ni buffer layer. But there are only randomly oriented polycrystalline grains in Cr buffered sandwiches. According to atomic force microscope topography, the surface roughness of Cr buffered sandwiches is smaller than that of Ni buffered ones. It is demonstrated that buffer layer influences both magnetic and Structural properties in Co/Cu/Co sandwiches as well as their GMR characteristics.Hollglie SHEN, Tie LI, Qinwo SHEN, Qiang PAN and Shichang ZOU (State Key Laboratory of Functional Materials for Informations and State Key Laboratories of Transducer Technology, Shanghai Institute of Metallurgy, Chinese Academy of Sciences, Shanghai 2000 2000Journal of Materials Science & Technology2000,16,2:2
18积极财政政策的国债规模限度风险研究显示文摘本文运用美国著名财政学家哈维S·罗森(Harvay·S·Rosen)的债务理财理论,对我国积极财政政策的国倩规模限度进行了风险评价。认为,对比美国有七、八十年长期发债的经久不衰历史,我国国债发行规模尚有相当的时间和空间潜力。文章指出问题的要害在于我国国债的运用效率低下,则是其风险所在。对策是改进我国国债的品种和时限等结构,完善国债市场。浙江省2000年度社科规划重点课题组 2001财经论丛(浙江财经学院学报)2001,,6:2
19Single rub-impacting periodic motions of a rigid constrained rotor system显示文摘This paper discusses the existence of single rub-impacting period-n motions for a kind of rotor systems with rigid constraints. The ranges of parameters for period-2 motions are also given. An example of this method is given.Qunhong LI and Qishao LU (School of Science, Beijing University of Aeronautics and Astronautics, Beijing 100082, China) (Received September 25, 2000) 2000Communications in Nonlinear Science and Numerical Simulation2000,5,4:2
20病毒性肝炎防治方案(试行)[J]显示文摘2000年西安全国传染病寄生虫病学术会议 中华传染病杂志0,,:2
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