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| 1 | Prevalence of vacA, cagA and babA2 genes in Cuban Helicobacter pylori isolates显示文摘AIM: To investigate the prevalence of vacuolating cytotoxin (vacA), cytotoxin associated gene A (cagA) and blood adhesion binding antigen (babA2) genotypes of Helicobacter pylori (H pylori) isolates from Cuban dyspeptic patients. METHODS: DNA was extracted from H pylori-positive cultures taken from 130 dyspeptic patients. Genotyping was performed by PCR, using specifi c primers for vacA (s1, s2, m1, m2), cagA and babA2 genes. Endoscopic observations and histological examinations were used to determine patient pathologies. RESULTS: vacA alleles s1 , s2 , m1 and m2 were detected in 96 (73.8%), 34 (26.2%), 75 (57.7%) and 52 isolates (40%), respectively, while the cagA gene was detected in 95 isolates (73.2%). One hundred and seven isolates (82.3%) were babA2-positive. A signif icant correlation was observed between vacAs1m1 and cagA and between vacAs1m1 and babA2 genotypes (P < 0.001 and P < 0.05, respectively) and between babA2 genotype and cagA status (P < 0.05); but, no correlation was observed between vacAs1 and babA2 genotypes. Eighty fi ve (65.4%) and 73 (56.2%) strains were type 1 (vacAs1-cagA-positive) and 'triple- positive' (vacAs1-cagA-babA2-positive), respectively, and their presence was significantly associated with duodenal ulcer (P < 0.01 and P < 0.001, respectively). CONCLUSION: The distribution of the main virulence factors in the Cuban strains in this study resembled that of the Western-type strains, and the more virulent H pylori isolates were signifi cantly associated with duodenal ulcer, ulcer disease being the worst pathology observed in the group studied. | Lino E Torres Karelia Melián Arlenis Moreno Jordis Alonso Carlos A Sabatier Mayrín Hernández Ludisleydis Bermúdez Boris L Rodríguez | 2009 | World Journal of Gastroenterology2009，15，2： | 4 |
| 2 | Successful operation of a cooperative SLR station of China and Argentina in San Juan显示文摘We introduced the observations and researches using a Satellite Laser Ranging (SLR) system with high precision, which was designed and made in China and installed in the Observatory of San Juan Uni- versity, Argentina, the capability of the system and the achievement of the cooperative procedure be- tween China and Argentina. The SLR station in San Juan, set up by China and Argentina, is quite sig- nificant for improving the distribution of SLR stations and enhancing the orbital coverage of the whole earth. Since the SLR system started to work in the Observatory of San Juan University in the beginning of 2006, the operation is rather good, and rich data with high precision have been obtained. Further plan of the cooperation for the near future is also presented. | HAN YanBen LIU WeiDong E ACTIS R PODESTA WANG TanQiang GUO TangYong QU Feng A M PACHECO A A GONZALEZ E ALONSO XIANG QingGe HUANG DongPing YIN ZhiQiang | 2008 | Chinese Science Bulletin2008，53，16： | 2 |
| 3 | Supercritical water oxidation process under energetically self-sufficient operation 显示文摘 | Cocero M J Alonso E Sanz M T | 2002 | Journal of Supercritical Fluids2002，24，1： | 2 |
| 4 | Effect of rain infiltration on the stability of slopes 显示文摘 | Alonso E Gens A Lioret A | 1995 | Unsaturated Soils1995，，1： | 1 |
| 5 | A constituteive model for partically saturated soils显示文摘 | Gens A Josa A | 1990 | Geotechnique1990，40，3： | 1 |
| 6 | Production of free conjugated linoleic acid by Lactobacillus acidophilus and Lactobacillus casei of human intestinal origin显示文摘 | ALONSO L CUESTA E P GILLILAND S E | 2003 | J Dairy Sci2003，86，6： | 1 |
| 7 | Contact pressures in the flexed hip joint during lateral trochanteric loading显示文摘 | Sparks D R Beason D P Etheridge B S Alonso J E Eberhardt A W | 2005 | J Orthop Res2005，23，： | 1 |
| 8 | Extended iliufemoral versus triradiate approaches in management of associated acetabular fractures显示文摘 | Alonso JE Davila R Bradley E | 1994 | Clin Orthop Relat Res1994，305，： | 1 |
| 9 | A constitutive model for partially saturated soils显示文摘 | Alonso E E Gens A Josa A | 1990 | Geotechnique1990，40，3： | 1 |
| 10 | Mantis shrimp allergy 显示文摘 | Alonso R E Zavala B B Escoda J M | 2006 | J Investig Allergol Clin Immunol2006，16，6： | 1 |
| 11 | Laryngeal tuberculosis显示文摘 | Porras Alonso E Martin Mateos A Perez-Requena J | 2002 | Rev Laryngol Otol Rhinol (Bord)2002，123，： | 1 |
| 12 | Characterization of aberrated laser beams 显示文摘 | ALDA J ALONSO J BERNABEU E | 1997 | J O S A1997，14，10： | 1 |
| 13 | Antibody binding and functional properties of whey protein hydrolysates obtained under high pressure显示文摘 | CHICON R BELLOQUE J ALONSO E | 2009 | Food Hydrocolloid2009，23，3： | 1 |
| 14 | On-line preconcentration using chelating and ion-exchange minicolumns for the speciation of chromium(iii) and chrontium(vi) and their quantitative determination in natural waters by inductively coupled plasma mass spectrometry显示文摘 | GUERRERO M M L ALONSO E V PAVON J M C | 2012 | Journal of Analytical Atomic Spectrometry2012，27，4： | 1 |
| 15 | Memory and strategic process- ing in first-degree relatives of obsessive-compulsive patients显示文摘 | Segalas C Alonso P Real E | 2010 | Psychol Med2010，40，12： | 1 |
| 16 | A consensus model for group decision making problems with unbalanced fuzzy linguistic information显示文摘 | Cabrerizo F J Alonso S Herrera-Viedma E | 2009 | Int J of Information Technology and Decision Making2009，8，1： | 1 |
| 17 | Speciation as a screening tool for the determination of heavy metal surface water pollution in the Guadiamar river basin显示文摘 | Alonso E Santos A Callejon M | 2004 | Chemosphere2004，56，6： | 1 |
| 18 | Secondary compression of clays as a local dehydration process显示文摘 | Navarro V Alonso E E | 2001 | Geotechnique2001，51，10： | 1 |
| 19 | Thermo -mechanical prop- erties of candelilla wax and dotriacontane organogels in saf- flower oil 显示文摘 | MORALES - RUEDA J A DIBILDOX - ALVARADO E CHAR- ALONSO M A | 2009 | Eur J Lipid Sci Tech2009，111，2： | 1 |
| 20 | Echocardiographic assessment of left ventricular hypertrophy :comparison to necropsy findings显示文摘 | Devereux R B Alonso D R Lutas E M | 1986 | Am J Cardiol1986，57，： | 1 |
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