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您的检索式：作者名="Umut Kefeli"
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| 1 | Colorectal stenting for palliation and as a bridge to surgery:A 5-year follow-up study显示文摘AIM: To evaluate the long-term effectiveness of colonic stents in colorectal tumors causing large bowel obstruction.METHODS: We retrospectively analyzed data from 49 patients with colorectal cancer who had undergone colorectal stent placement between January 2008 and January 2013. Patients' symptoms,characteristics and clinicopathological data were obtained by reviewing medical records. The obstruction was diagnosed clinically and radiologically. Histopathological diagnosis was achieved endoscopically. Technical success rate(TSR)was defined as the ratio of patients with correctly placed SEMS upon stent deployment across the entire stricture length to total number of patients. Clinical success rate(CSR) was defined as the ratio of patients with technical success and successful maintenance of stent function before elective surgery(regardless of number of SEMS deployed) to total number of patients. The surgical success rate(SSR) of colorectal stent as a bridge to surgery was defined as the ratio of patients with successful surgical procedures. Unsuccessful surgical outcomes were defined as being due to insufficient colonic decompression. The technical,clinical,surgical success rates and complications after stenting were assessed.RESULTS: The median age of patients was 64(36 to 89). 44.9% of patients were male and 55.1% were female. Eighteen patients had the obstruction located in the rectum,15 patients in the rectosigmoid region,10 patients in the sigmoid region,and 6 patients had a tumor causing obstruction in the proximal colon. Each patient was categorized pathologically as stage 2(32.7%,16 patients) or stage 3(42.9%,21 patients) and 12 patients(24.4%) had metastatic disease. None of the patients received chemotherapy before stenting. Stenting was undertaken in 37 patients as a bridge to surgery,and in 12 patients stents were used for palliation. Median time to surgery after stenting was 30 ± 91.9 d. All surgery was completed in one single operation and thus no colostomy with stoma was needed. The median overall survival rate of patients with stage 2-3 colorectal cancer was 53.1 mo and stage 4 was 37.1 mo(P = 0.04). Metastatic colorectal patients who were treated palliatively with stents had backbone chemotherapy with oxaliplatin and/or irinotecan-based regimens plus antiangiogenic therapies,especially bevacizumab. Resolution of the obstruction and clinical improvement was achieved in all patients. The technical,clinical and surgical success rates were 95.9%,100% and 94.6%,respectively.CONCLUSION: The efficacy and safety of colonic stents was demonstrated both as a bridge to surgery and for palliative decompression. In addition,results emphasize the importance of the skills of the endoscopist in colonic stenting. | Baris Bayraktar Ibrahim Ali Ozemir Umut Kefeli Gokhan Demiral Julide Sagiro?lu Onur Bayraktar Gupse Adali Alp Ozcelik Osman Baran Tortum | 2015 | World Journal of Gastroenterology2015，21，31： | 3 |
| 2 | Prognostic Significance of Perineural Invasion in Patients with Gastric Cancer Who Underwent Curative Resection显示文摘 | Ahmet Bilici MD Mesut Seker MD Bala Basak Oven Ustaalioglu MD Umut Kefeli MD Emre Yildirim MD Dilek Yavuzer MD Fatih Muhammed Aydin MD Taflan Salepci MD Mustafa Oncel MD FASCRS(Int) Mahmut Gumus MD | 2010 | Annals of Surgical Oncology2010，，8： | 1 |
| 3 | Prognostic Significance of Perineural Invasion in Patients with Gastric Cancer Who Underwent Curative Resection显示文摘 | Ahmet Bilici Mesut Seker Bala Basak Oven Ustaalioglu Umut Kefeli Emre Yildirim Dilek Yavuzer Fatih Muhammed Aydin Taflan Salepci Mustafa Oncel Mahmut Gumus | 2010 | Annals of Surgical Oncology2010，，8： | 1 |
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