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| 1 | 利用ML振幅研究地壳横波Q值Ⅱ:Q横向变化特征显示文摘利用中国地震年报(1984-2004年)测定ML所用的54000余条区域地震最大振幅数据,采用二维层析成像方法反演中国大陆地壳介质品质因子Q0结构.反演结果表明,中国大陆地壳介质品质因子Q0平均为370,Q0横向变化量可达±200.在整个研究区解的分辨率能够达到3°×3°,大部分地区能够达到2°×2°.Q0的变化显示出与地质构造分区相关的特征:低衰减(高Q0值)异常区主要分布在塔里木盆地、四川盆地、鄂尔多斯高原及华南地区,鄂尔多斯高原北部Q0值最高;高衰减异常区(低Q0值)主要分布在青藏高原以东的川滇地区、华北平原、渤海湾,最低Q0值在渤海湾地区,天山、祁连山和汾渭地堑Q0也呈较低异常变化.总体看来,构造上稳定的克拉通地台的介质品质因子Q0较高,而构造上活动的地区往往Q0较低,显现出区域的衰减变化特征与地壳结构和区域构造之间的密切关系. | 汪素云 裴顺平 Thomas M. Heam 许忠淮 James F. Ni 俞言祥 | 2008 | 地球物理学报2008，51，1： | 30 |
| 2 | 缺血性卒中的一级预防——美国心脏协会/美国卒中协会卒中委员会指南 动脉粥样硬化性周围血管病跨学科工作组、心血管护理委员会、临床心脏病学委员会、营养、体力活动和代谢委员会以及医疗质量和转归研究跨学科工作组共同倡导显示文摘背景和目的本指南提供有关各种确定和潜在的卒中危险因素证据的概述,并提供降低卒中风险的推荐。方法写作组成员由委员会主席根据每位作者先前在相关课题领域中的工作提名,并经美国心脏协会(AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾(涵盖时间段为2001年最后一次回顾发表到2005年1月),参考先前已发表的指南、个人文件和专家意见来概括现有的证据,指明现有知识的差距;如果合适,则根据标准的AHA标准做出简明的推荐。写作组全体成员在撰写过程中均有很多机会对推荐进行评论并认可这份声明的最终版本。在AHA科学咨询与协调委员会批准之前,本指南已进行过广泛的同行评议。结果对评价个体首次卒中风险的流程图进行评估。根据干预的可能性(不可干预、可干预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预的危险因素包括年龄、性别、出生体重低、人种/种族和遗传因素。证据充分的可干预危险因素包括高血压、主动或被动吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、缺乏体力活动、肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、脂蛋白相关的磷脂酶升高、高凝状态、炎症和感染。对应用阿司匹林进行卒中一级预防的资料进行回顾。结论有大量证据可以用于确定增加首次卒中风险的各种特殊因素和提供降低这种风险的策略。 | Larry B. Goldstein Robert Adams Mark J. Alberts Lawrence J. Appel Lawrence M. Brass Cheryl D. Bushnell Antonio Culebras Thomas J. DeGraba Philip B. Gorelick John R. Guyton Robert G. Hart George Howard Margaret Kelly-Hayes J.V. (Ian) Nixon Ralph L. Sacco 苏克江 高宗恩 | 2006 | 国际脑血管病杂志2006，14，8： | 28 |
| 3 | 氢化物发生-多接收杯电感耦合等离子体质谱同位素稀释法测定硒同位素显示文摘使用改进的巯基棉分离流程和74硒-77硒双稀释剂,在氢化物(HG)-多接收器电感耦合等离子体质谱仪(MC-ICP-MS)实现了高精度硒同位素组成的测定。巯基棉用于分离样品基质中的硒,随后使用HNO3+H2O2消除干扰的有机质,74硒-77硒双稀释剂校正样品分离和质谱测定过程中的硒同位素质量分馏。硒标准溶液NISTSRM3149和MH495几个月的测定表明,该方法的外精度为0.1‰(2σ),样品的外精度为0.15‰~0.2‰(2σ)。以TCF分离硒的平均回收率85%计算,最小硒需要量为20ng。实验结果以相对于NISTSRM3149的δ82/76Se表达,δM82H/74965/SRM3149=-3.44±0.1‰(2σ),优于已发表的数据δ8M2H/74965/SRM3149=-3.04±0.5‰。测定样品的δ8S2R/M736149为-13.53‰~11.37‰,为硒同位素在环境、农业、生命和地球科学中的拓展应用与发展奠定了基础。 | 朱建明 Johnson Thomas M. Clark Scott K. 朱祥坤 | 2008 | 分析化学2008，36，10： | 16 |
| 4 | Reforestation Programs in Southwest China:Reported Success,Observed Failure, and the Reasons Why显示文摘Ever since the disastrous floods of 1998, the Chinese government has used the Natural Forest Protection and Sloping Land Conversion Programs to promote afforestation and reforestation as means to reduce runoff, control erosion, and stabilize local livelihoods. These two ambitious programs have been reported as large-scale successes, contributing to an overall increase in China’s forest cover and to the stated goals of environmental stabilization. A small-scale field study at the project level of the implementation of these two programs in Baiwu Township, Yanyuan County, Sichuan, casts doubt upon the accuracy and reliability of these claims of success; ground observations revealed utter failure in some sites and only marginal success in others. Reasons for this discrepancy are posited as involving ecological, economic, and bureaucratic factors. Further research is suggested to determine whether these discrepancies are merely local aberrations or represent larger-scale failures in reforestation programs. | Christine Jane Trac Stevan Harrell Thomas M. Hinckley Amanda C. Henck | 2007 | Journal of Mountain Science2007，4，4： | 13 |
| 5 | 在变化的金融体系中维护金融稳定:吸取历史教训显示文摘本文为美国堪萨斯联储行长、经济学家Hoeing在EMEAP-BCBS-FSI联合举办的亚太区银行监管高级会议上的主题发言。本文以金融结构演进为切入点,从理论层面分析了次贷危机的根源及对现行监管制度和维护金融体系稳定政策带来的挑战。作者的观点有助于业界深入思考金融市场化取向的改革、金融创新的利弊、金融监管制度乃至金融稳定政策的调整等重大前沿性问题。 | Thomas M. Hoeing 王胜邦(译) 曾智萍(译) | 2008 | 新金融2008，，1： | 10 |
| 6 | Signaling in Early Maize Kernel Development显示文摘 | Nicolas M. Doll Nathalie Depege-Fargei Peter M. Rogowsky Thomas Widiez | 2017 | Molecular Plant2017，10，3： | 9 |
| 7 | Influence of groundwater depth on species composition and community structure in the transition zone of Cele oasis显示文摘The paper analyzes the hypothesis that the distribution of dominant plant species and characteristics of plant communities are related to groundwater depth. The results showed that variations of groundwater depth impacted distributions and characteristics of dominant plant communities. However, besides groundwater depth, the community composition and species diversity were also influenced by physiognomy of the habitat. Based on the similarity coefficient, the differences between dominant plant communities were significant at different groundwater depths. Compared with other results relating to desert vegetation and groundwater depth, variations of community distribution were similar at the large spatial scale. However, in this extremely arid region, there were significant differences in community type and community succession when compared with other arid regions, especially in relationship to deep groundwater depth. With groundwater depth from deep to shallow, communities transformed with the sequence of Alhagi communities, Tamarix spp. communities, Populus communities, Phragmites communities, and Sophora communities. At groundwater depth of less than 6.0 m, the community type and composition changed, and the species diversity increased. Among these dominant species, Tamarix exhibited the biggest efficiency in resource utilization according to niche breadth, which means it possessed the best adaptability to environmental conditions at the oasis margins. | Frank M. THOMAS | 2010 | Journal of Arid Land2010，2，4： | 9 |
| 8 | 青少年运动缺乏症(EDD)研究的10大问题显示文摘运动缺乏症(EDD)是一种儿科疾病,特点是中高强度体力活动(MVPA)下降,低于目前的推荐量,也与积极的健康结果不一致。目前,大多数儿童和青少年符合EDD的诊断标准,因为他们没有达到日常MVPA的最低要求。本文的目的是强调10个与青少年EDD有关的重要研究问题。需要进行重要的研究来更好地定义EDD的临床表现,包括评估体力活动行为以确定开始出现EDD的年龄或发育阶段;包括运动技巧和体能的运动起源(kinesiogenesis)的检测;以及对影响青少年MVPA的生活方式因素的评估。关于治疗EDD的干预措施和政策的研究问题,包括评估对卫生保健从业者进行运动医学重要性的教育和训练;确定在临床上识别和治疗EDD青少年的方法的有效性;开发敏感的、特效的、经济的方法以诊断青少年EDD;以及定制方法以促进本病诊疗的医疗保险赔付。如果未来研究不能优化EDD青少年的识别、治疗和管理方案,具有重大影响的生物医学、心理、经济和政治的新的卫生保健问题将会不断出现。 | Avery D. Faigenbam Thomas M. Best James MacDonald Gregory D. Myer Andrea Stracciolini | 2015 | 北京体育大学学报2015，38，11： | 8 |
| 9 | 高温高压水中镍和铬表面氧化膜的原位表面增强型拉曼光谱研究显示文摘采用原位表面增强型拉曼光谱方法,研究了铬和镍在高温高压水中生成的表面氧化膜。镍氧化膜的拉曼光谱峰在540cm-1处,对应于NiO膜中形成的缺陷。电位小于-0.75V时,弱540cm-1峰源于样品表面的残余氧化物。电位大于-0.7V时,540cm-1峰较强,镍表面已生成稳定的NiO膜。铬氧化膜拉曼光谱有1个540cm-1强峰和1个610cm-1弱峰,对应于CrOOH或Cr2O3或两者的混合物。电位增大时,610cm-1峰强度减小,可能是因为氧化物从CrOOH转变成Cr2O3。本文的研究结果为Ni-Cr合金表面氧化物的判定提供了依据。 | 汪峰 Thomas M. Devine | 2013 | 原子能科学技术2013，47，B12： | 7 |
| 10 | Non-transgenic Plant Genome Editing Using Purified Sequence-Specific Nucleases显示文摘Dear Editor, Sequence-specific nucleases,including zinc-finger nucleases,meganucleases,TAL effector nucleases (TALENs),and CRISPR/ Cas systems,have been used to introduce targeted mutations in a wide range of plant species (Voytas,2013;Baltes and Voytas,2015).However,delivery of these nucleases using traditional transformation methods (e.g.,particle bombardment,Agrobacterium or protoplast transformation) may result in undesired genetic alterations due to random insertion of nucleaseencoding DNA intothe host genome. | Song Luo Jin Li Thomas J. Stoddard Nicholas J. Baltes Zachary L. Demorest Benjamin M. Clasen Andrew Coffman Adam Retterath Luc Mathis Daniel F. Voytas Feng Zhang | 2015 | Molecular Plant2015，8，9： | 7 |
| 11 | Interleukin-28B Polymorphism Improves Viral Kinetics and Is the Strongest Pretreatment Predictor of Sustained Virologic Response in Genotype 1 Hepatitis C Virus显示文摘 | Alexander J. Thompson Andrew J. Muir Mark S. Sulkowski Dongliang Ge Jacques Fellay Kevin V. Shianna Thomas Urban Nezam H. Afdhal Ira M. Jacobson Rafael Esteban Fred Poordad Eric J. Lawitz Jonathan McCone Mitchell L. Shiffman Greg W. Galler William M. Lee | 2010 | Gastroenterology2010，，1： | 7 |
| 12 | 使用二硫化硒洗发水持续改善经酮康唑治疗后的轻中度脂溢性皮炎的临床症状和重建头皮微生态平衡显示文摘脂溢性皮炎是好发于头皮等皮脂溢出部位的一种慢性、复发性炎症性皮肤病,主要表现为红斑、轻中度油腻性痂屑,有时伴有瘙痒,当仅表现为轻度鳞屑而不伴有明显炎症时,又称为头皮屑。各种环境、内源性和宿主免疫因素可能加剧脂溢性皮炎发展,引起皮脂腺功能、皮脂成分、表皮屏障功能、皮肤浅部真菌定植的改变,最终导致炎症。在这些因素中,亲脂性马拉色菌属可能起到关键作用。在种属层面上,限制性马拉色菌和球形马拉色菌是与健康头皮相关的最常见的真菌。此外,皮肤细菌菌群的改变也可能参与脂溢性皮炎的发病机制。在脂溢性皮炎/头皮屑头皮中,细菌表现为更高的多样性,相应地表现为葡萄球菌(较高)和丙酸杆菌(较低)两种优势细菌之间的比例失衡。 | Massiot P. Clavaud C. Thomas M. 陈旭 牛悦青 | 2021 | 中华皮肤科杂志2021，54，11： | 6 |
| 13 | Camouflage Patterning in Maize Leaves Results from a Defect in Porphobilinogen Deaminase显示文摘玉米叶子从导致沿着叶的长轴穿的同种细胞的房间系的极化的房间部门被生产。我们利用了这个 stereotypical 部门模式识别形成违背同种细胞的房间系的叶绿体色素沉着部门的许多异种。这里,我们描述 camouflage1 (cf1 ) 异种,开发 nonclonal,在它的叶子的 yellowgreen 部门。我们由标注的 transposon 克隆 cf1 基因并且决定它编码 porphobilinogen 脱氨基酶(PBGD ) ,在叶绿素和 heme 早工作的酶生合成。当 PBGD 生物化学地被描绘了时,在这基因的可行变化都没在植物被报导。调查在里面 PBGD 的 vivo 功能,我们描绘了 cf1 异种。组织学的分析表明 cf1 黄扇区显示捆鞘的新奇显型房间特定的死亡。轻移动的实验决定经常的光压制了 cf1 部门形成,黑暗 / 轻的转变被要求仅仅在叶开发的一有限时间期间导致黄部门,和那种部门形式。生物化学的实验决定 cf1 异种叶子减少了 PBGD 活动和在绿、黄的区域的酶底层的增加的层次。而且, cf1 黄区域在过氧化氢酶活动显示了减小。一个阀值模型被假设向 cf1 解释上色并且合并光合的细胞区别,清除的反应的氧种,和 PBGD 功能。 | Mingshu Huanga Thomas L. Slewinski R. Frank Baker , Diane Janick-Buckner Brent Buckner Gurmukh S. Johal David M. Braun | 2009 | Molecular Plant2009，2，4： | 6 |
| 14 | Efficient fully laser-patterned flexible perovskite modules and solar cells based on low-temperature solution-processed SnO2/mesoporous-TiO2 electron transport layers显示文摘 | Janardan Dagar Sergio Castro-Hermosa Matteo Gasbarri Alessandro L. Palma Lucio Cina Fabio Matteocci Emanuele Calabro Aldo Di Carlo Thomas M. Brown | 2018 | Nano Research2018，11，5： | 6 |
| 15 | Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate显示文摘Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play key roles in programming the epigenome and facilitating recruitment of additional regulatory factors during successive cell lineage specification and differentiation steps. Here we show that Isl1 acts as a pioneer factor driving cardiomyocyte lineage commitment by shaping the chromatin landscape of cardiac progenitor cells. Using an Isl1 hypomorphic mouse line which shows congenital heart defects, genome-wide profiling of Isl1 binding together with RNA- and ATAC-sequencing of cardiac progenitor cells and their derivatives, we uncover a regulatory network downstream of Isl1 that orchestrates cardiogenesis. Mechanistically, we show that Isl1 binds to compacted chromatin and works in concert with the Brg1-Baf60c-based SWI/SNF complex to promote permissive cardiac lineage-specific alterations in the chromatin landscape not only of genes with critical functions in cardiac progenitor cells, but also of cardiomyocyte structural genes that are highly expressed when Isl1 itself is no longer present. Thus, the Isl1/Brg1-Baf60c complex plays a crucial role in orchestrating proper cardiogenesis and in establishing epigenetic memory of cardiomyocyte fate commitment. | Rui Gao Xingqun Liang Sirisha Cheedipudi Julio Cordero Xue Jiang Qingquan Zhang Luca Caputo Stefan Günther Carsten Kuenne Yonggang Ren Shoumo Bhattacharya Xuejun Yuan Guillermo Barreto Yihan Chen Thomas Braun Sylvia M. Evans Yunfu Sun Gergana Dobreva | 2019 | Cell Research2019，29，6： | 5 |
| 16 | Pre-osteoblastic MC3T3-E1 cells promote breast cancer growth in bone in a murine xenograft model显示文摘The bones are the most common sites of breast cancer metastasis. Upon arrival within the bone microenvironment, breast cancer cells coordinate the activities of stromal cells, resulting in an increase in osteoclast activity and bone matrix degradation. In late stages of bone metastasis, breast cancer cells induce apoptosis in osteoblasts, which further exacerbates bone loss. However, in early stages, breast cancer cells induce osteoblasts to secrete inflammatory cytokines purported to drive tumor progression. To more thoroughly evaluate the role of osteoblasts in early stages of breast cancer metastasis to the bones, we used green fluorescent protein-labeled human breast cancer cell lines MDA-MB-231 and MDA-MB-435, which both induce osteolysis after intra-femoral injection in athymic mice, and the murine pre-osteoblastic cell line MC3T3-E1 to modulate osteoblast populations at the sites of breast cancer metastasis. Breast cancer cells were injected directly into the femur with or without equal numbers of MC3T3-E1 cells. Tumors grew significantly larger when co-injected with breast cancer cells and MC3T3-E1 cells than injected with breast cancer cells alone. Osteolysis was induced in both groups, indicating that MC3T3-E1 cells did not block the ability of breast cancer cells to cause bone destruction. MC3T3-E1 cells promoted tumor growth out of the bone into the extraosseous stroma. These data suggest that breast cancer cells and osteoblasts communicate during early stages of bone metastasis and promote tumor growth. | Thomas M. Bodenstine Benjamin H. Beck Xuemei Cao Leah M. Cook Aimen Ismail J. Kent Powers Andrea M. Mastro Danny R. Welch | 2011 | Chinese Journal of Cancer2011，30，3： | 5 |
| 17 | 采用实体瘤疗效评价标准、改良实体瘤疗效评价标准和体积测定法MRI评价恶性胸膜间皮瘤治疗反应与CT的对照性研究显示文摘本研究的目的是采用实体瘤疗效评价标准(response evaluation criteria in solid tumours,RECIST)和改良的RECIST与CT对照比较来评价MRI技术在判断恶性胸膜间皮瘤(MPM)病人的早期治疗反应。50例恶性胸膜间皮瘤病人(男32例,女18例)在9周的疗程之后[6次化疗(CHT)中的3次]评价早期治疗反应。此外,还对病人在化疗前、早期治疗反应评价后4周和6个化疗周期后的诊断性随访进行评价。RECIST和改良RECIST用于CT和MRI检查[半傅里叶单次激发快速自旋回波(HASTE)、容积式内插值法屏气检查(VIBE)、T2-快速自旋回波序列]。 | C. Plathow M. Klopp C. Thieke F. Herth A. Thomas A. Schmaehl 叶锦棠(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 4 |
| 18 | AHA/ACC Guidelines for Secondary Prevention for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update: Endorsed by the National Heart, Lung, and Blood Institute显示文摘 | Sidney C. Smith Jerilyn Allen Steven N. Blair Robert O. Bonow Lawrence M. Brass Gregg C. Fonarow Scott M. Grundy Loren Hiratzka Daniel Jones Harlan M. Krumholz Lori Mosca Richard C. Pasternak Thomas Pearson Marc A. Pfeffer Kathryn A. Taubert | 2006 | Circulation2006，，19： | 4 |
| 19 | Outcomes of EUS-guided drainage of debris-containing pancreatic pseudocysts by using combined endoprosthesis and a nasocystic drain显示文摘 | Ali A. Siddiqui John M. DeWitt Anna Strongin Harkirat Singh Smoker Jordan David E. Loren Thomas Kowalski Mohamad A. Eloubeidi | 2013 | Gastrointestinal Endoscopy2013，，： | 4 |
| 20 | Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure显示文摘 | Rusty L. Montgomery Thomas G. Hullinger Hillary M. Semus Brent A. Dickinson Anita G. Seto Joshua M. Lynch Christianna Stack Paul A. Latimer Eric N. Olson Eva van Rooij | 2011 | Circulation2011，，14： | 4 |
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