|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 肺癌分期分类相关的解剖学、生物学及理念显示文摘尽管用于此修订本的大样本量患者数据库已极大地拓宽了我们的知识面,但最新提出的肺癌分期系统仍以解剖学特征为基础。可以预见,由于所鉴定出的患者亚群数目不断增加,肺癌分期系统变得愈加复杂。表述这些亚组的临床特征有可能为我们提供肿瘤亚组特殊的生物学行为特性的线索。本文探索了可用于以解剖学为基础的新分期系统的肿瘤生物学相关观念。 | Frank C. DETTERBECK Lynn T. TANOUE Daniel J. BOFFA 杨永波 李志刚 | 2010 | 中国肺癌杂志2010，，1： | 11 |
| 2 | Decoding altitude-activated regulatory mechanisms occurring during apple peel ripening显示文摘Apple(Malus domestica Borkh)is an important fruit crop cultivated in a broad range of environmental conditions.Apple fruit ripening is a physiological process,whose molecular regulatory network response to different environments is still not sufficiently investigated and this is particularly true of the peel tissue.In this study,the influence of environmental conditions associated with low(20 m)and high(750 m)altitude on peel tissue ripening was assessed by physiological measurements combined with metabolomic and proteomic analyses during apple fruit development and ripening.Although apple fruit ripening was itself not affected by the different environmental conditions,several key color parameters,such as redness and color index,were notably induced by high altitude.Consistent with this observation,increased levels of anthocyanin and other phenolic compounds,including cyanidin-3-O-galactoside,quercetin-3-O-rhamnoside,quercetin-3-O-rutinoside,and chlorogenic acid were identified in the peel of apple grown at high altitude.Moreover,the high-altitude environment was characterized by elevated abundance of various carbohydrates(e.g.,arabinose,xylose,and sucrose)but decreased levels of glutamic acid and several related proteins,such as glycine hydroxymethyltransferase and glutamate–glyoxylate aminotransferase.Other processes affected by high altitude were the TCA cycle,the synthesis of oxidative/defense enzymes,and the accumulation of photosynthetic proteins.From the obtained data we were able to construct a metabolite-protein network depicting the impact of altitude on peel ripening.The combined analyses presented here provide new insights into physiological processes linking apple peel ripening with the prevailing environmental conditions. | Evangelos Karagiannis Michail Michailidis Georgia Tanou Federico Scossa Eirini Sarrou George Stamatakis Martina Samiotaki Stefan Martens Alisdair R.Fernie Athanassios Molassiotis | 2020 | Horticulture Research2020，7，1： | 3 |
| 3 | Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria显示文摘 | Ivaylo I. Ivanov Koji Atarashi Nicolas Manel Eoin L. Brodie Tatsuichiro Shima Ulas Karaoz Dongguang Wei Katherine C. Goldfarb Clark A. Santee Susan V. Lynch Takeshi Tanoue Akemi Imaoka Kikuji Itoh Kiyoshi Takeda Yoshinori Umesaki Kenya Honda Dan R. Littma | 2009 | Cell2009，，3： | 3 |
| 4 | Primary site resection is superior for incurable metastatic colorectal cancer显示文摘AIM:To investigate survival in patients treated with FOLFOX followed by primary site resection or palliative surgery for incurable metastatic colorectal cancer. METHODS:Between 2001 and 2009,a total of 98 patients with colorectal adenocarcinoma and non-resectable metastases were diagnosed and treated with the new systemic agent chemotherapy regimen FOLFOX. Primary site resection was carried out in 38 patients, creation of a colostomy or bypass without resection was carried out in 36 patients,and 23 were not operated on because of advanced disease.The survival times of patients in different groups were analyzed. RESULTS:There were no differences between the patients regarding their general condition,concurrent disease,or tumor stage according to AJCC classification.The median survivals of the three groups were 30.6,20.8,and 12.7 mo(log-rank P value<0.05),respectively.The postoperative complication rate was higher in the primary site resection group than in the palliative surgery group. CONCLUSION:The results indicate that there are benefits from primary site resection for incurable metastatic colorectal cancer with systemic chemotherapy. | Yusuke Tanoue Nobutaka Tanaka Yukihiro Nomura | 2010 | World Journal of Gastroenterology2010，16，28： | 2 |
| 5 | The new lung cancer staging system 显示文摘 | Detterbeck FC Boffa DJ Tanoue LT | 2009 | Chest2009，136，1： | 1 |
| 6 | Molecular mass distribution and fluores- cence characteristics of dissolved organic ligands for copper (Ⅱ) in lake Biwa,Japan 显示文摘 | WU F TANOUE E | 2001 | Organic Geochemistry2001，32，： | 1 |
| 7 | Three-dimensional recon-structed images after rotational angiography in the evaluation of intracranial aneurysm: surgical correlation 显示文摘 | Tanoue S Kiyosue H Kenai H | 2000 | Neurosurgery2000，47，4： | 1 |
| 8 | Physical mapping of the rice genome with YAC clones显示文摘 | Kurata N Umehara Y Tanoue H | 1997 | Plant Mol Biol1997，3，12： | 1 |
| 9 | The new lung cancer stagingsystem显示文摘 | Detterbeck FC Boffa DJ Tanoue LT | 2009 | Chest2009，136，1： | 1 |
| 10 | New TNM classification for non-small-cell lung cancer显示文摘 | Tanoue LT Detterbeck FC | 2009 | Expert Rev Anticancer Ther2009，9，4： | 1 |
| 11 | Mechanical design of an intracranial stent for treating cerebral aneurysms显示文摘 | SHOBAYASHI Y TANOUE T TATESHIMA S | 2010 | Med Eng Phys2010，32，： | 1 |
| 12 | Unenhanced magnetic resonance angiography with time-spatial labeling inversion pulse for evaluating visceral artery aneurysms after en- dosaccular packing with detachable coils:Preliminary re- suits显示文摘 | Maruno M Kiyosue H Tanoue S | 2013 | Journal of Vascular and Interventional Radiolo- gy2013，24，2： | 1 |
| 13 | Induction of colonic regulatory T cells by indigenous Clostridium species显示文摘 | Atarashi K Tanoue T Shima T | 2011 | Sci- ence2011，331，6015： | 1 |
| 14 | Effectiveness of two-liquid silane primers on bonding sintered feldspathic porcelain with a dual-cured composite luting agent显示文摘 | Nogami T Tanoue N Atsuta M | 2004 | J Oral Rehabil2004，31，8： | 1 |
| 15 | Molecular characterization of a membrane-bound c GMP dependent protein kinase from protein kinase from the silk moth Bombyx mori显示文摘 | TANOUE S NISHIOKA T | 2003 | Insect Mol Biol2003，12，6： | 1 |
| 16 | Detection of the residual lumen of intracranial aneurysms immediately after coil embolization by three-dimensional digital subtraction angiographic virtual endoscopic imaging 显示文摘 | Kiyosue H Okahara M Tanoue S | 2002 | Neurosurgery2002，50，3： | 1 |
| 17 | Dissolved organic matter in oceanic waters显示文摘 | OGAWA H TANOUE E | 2003 | Journal of Oceanography2003，59，： | 1 |
| 18 | The new lung cancer staging system显示文摘 | DETTERBECK F C BOFFA D J TANOUE L T | 2009 | Chest2009，136，1： | 1 |
| 19 | Induction of colonic regulatory T cells by indigenous Clostridium species显示文摘 | Atarashi K Tanoue T Shima T | 2011 | Science2011，331，6015： | 1 |
| 20 | Tbl 7 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells 显示文摘 | Atarashi K Tanoue T Ando M el at | 2015 | Cell2015，163，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员