|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The characteristics, origins, and geodynamic settings of supergiant gold metallogenic provinces显示文摘There are six distinct classes of gold deposits, each represented by metallogenic provinces, having 100’s to > 1 000 tonne gold production. The deposit classes are: (1) erogenic gold; (2) Carlin and Carlin-like gold deposits; (3) epithermal gold-silver deposits; (4) copper-gold porphyry deposits; (5) iron-oxide copper-gold deposits; and (6) gold-rich volcanic hosted massive sul-fide (VMS) to sedimentary exhalative (SEDEX) deposits. This classification is based on ore and alteration mineral assemblages; ore and alteration metal budgets; ore fluid pressure(s) and compositions; crustal depth or depth ranges of formation; relationship to structures and/or magmatic intrusions at a variety of scales; and relationship to the P-T-t evolution of the host terrane. These classes reflect distinct geodynamic settings. Orogenic gold deposits are generated at mid-crustal (4-16 km) levels proximal to terrane boundaries, in transpressional subduction-accretion complexes of Cordilleran style erogenic belts; other | Robert Kerrich Richard Goldfarb David Groves Steven Garwin | 2000 | Science China Earth Sciences2000，43，S1： | 249 |
| 2 | Constituents of the anti-asthma herbal formula ASHMI^(TM) synergistically inhibit IL-4 and IL-5 secretion by murine Th2 memory cells,and eotaxin by human lung fibroblasts in vitro显示文摘OBJECTIVE:Anti-asthma herbal medicine intervention(ASHMI ),a combination of three traditional Chinese medicinal herbs developed in our laboratory,has demonstrated efficacy in both mouse models of allergic asthma,and a double-blind placebo-controlled clinical trial in patients with asthma.This study was designed to determine if the anti-inflammatory effects of individual herbal constituents of ASHMI? exhibited synergy. METHODS:Effects of ASHMI and its components aqueous extracts of Lingzhi(Ganoderma lucidum),Kushen(Sophora flavescens) and Gancao(Glycyrrhiza uralensis),on Th2 cytokine secretion by murine memory Th2 cells(D10.G4.1) and eotaxin-1 secretion by human lung fibroblast(HLF-1) cells were determined by measuring levels in culture supernatants by enzymelinked immunosorbent assay.Potential synergistic effects were determined by computing interaction indices from concentration-effect curve parameters. RESULTS:Individual Lingzhi,Kushen and Gancao extracts and ASHMI(the combination of individual extracts) inhibited production of interleukin(IL)-4 and IL-5 by murine memory Th2 cells and eotaxin-1 production by HLF-1 cells.The mean 25%-inhibitory-concentration(IC25) values(mg/mL) for ASHMI,Lingzhi,Kushen and Gancao for IL-4 production were 30.9,79.4, 123,and 64.6,respectively;for IL-5 production were 30.2,263,123.2 and 100,respectively; for eotaxin-1 were 13.2,16.2,30.2,and 25.1,respectively.The IC50 values(mg/mL) for ASHMI,Lingzhi,Kushen and Gancao for IL-4 production were 158.5,239.9,446.7,and 281.8, respectively;for eotaxin-1 were 38.1,33.1,100,and 158.5,respectively.The interaction indices of ASHMI constituents at IC25 were 0.35 for IL-4,0.21 for IL-5 and 0.59 for eotaxin-1.The interaction indices at IC50 values were 0.50 for IL-4 and 0.62 for eotaxin-1 inhibition.Inhibition of IL-5 did not reach IC50 values.All interaction indices were below 1 which indicated synergy. CONCLUSION:By comparing the interaction index values,we find that constituents in ASHMI? synergistically inhibited eotaxin-1 production as well as Th2 cytokine production. | Bolleddula Jayaprakasam Nan Yang Ming-Chun Wen Rong Wang Joseph Goldfarb Hugh Sampson Xiu-Min Li | 2013 | Journal of Integrative Medicine2013，11，3： | 15 |
| 3 | 超大型金成矿省的地球动力学背景(摘要)显示文摘 | R. Kerrich R. Goldfarb D. Groves S.Garwin Y. Jia 张静 | 2000 | 中国科学(D辑)2000，30，B12： | 3 |
| 4 | Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria显示文摘 | Ivaylo I. Ivanov Koji Atarashi Nicolas Manel Eoin L. Brodie Tatsuichiro Shima Ulas Karaoz Dongguang Wei Katherine C. Goldfarb Clark A. Santee Susan V. Lynch Takeshi Tanoue Akemi Imaoka Kikuji Itoh Kiyoshi Takeda Yoshinori Umesaki Kenya Honda Dan R. Littma | 2009 | Cell2009，，3： | 3 |
| 5 | Strategies for preveting calcium oxalate stones 显示文摘 | FINKIELSTEIN VA GOLDFARB DS | 2005 | CMAJ2005，174，10： | 1 |
| 6 | Growth hormone reserve inadult beta thalassemia patients 显示文摘 | Vidergor G Goldfarb AW Glaser B | 2007 | Endocrine2007，31，1： | 1 |
| 7 | Choroid plexus tumors in children: significance of stromal invasion显示文摘 | Goldfarb A Hyder DJ | 2001 | Neurosurgery2001，48，2： | 1 |
| 8 | Synthesis of mesoporous manganosilicates: Mn-MCM-41, Mn-MCM-48 and Mn-MCM-41显示文摘 | Zhao D Y Goldfarb D | 1995 | J Chem Soc Chem Commun1995，，8： | 1 |
| 9 | Tectonic setting of synorogenic gold deposits of the Pacific Rim显示文摘 | Goldfarb R J Phillips G N Nokleherg W J | 1998 | Ore Geology Reviews1998，13，： | 1 |
| 10 | Renal outcome 25 years after donor nephrectomy显示文摘 | Goldfarb DA Matin SF Braun WE | 2001 | J Urol2001，166，6： | 1 |
| 11 | Dorsal locked plate fixation of dis?tal radius fractures显示文摘 | Lutsky K Boyer M Goldfarb C | 2013 | J Hand Surg Am2013，38，7： | 1 |
| 12 | Pathogenosis of contrast-induced ne- phropathy experimental and clinical observations with emphasis on the role of osmolality 显示文摘 | Rudnick MR Goldfarb S | 2003 | Rev Cardiovasc Med2003，4，5： | 1 |
| 13 | Importin alpha:a multipurpose nuclear-transport receptor显示文摘 | Goldfarb D S Corbett A H Mason D A | 2004 | Trends Cell Biol2004，14，9： | 1 |
| 14 | Bregman iterative algorithms for l1-minimization with applications to compressed sensing显示文摘 | YIN W OSHER S GOLDFARB D | | 0，，01： | 1 |
| 15 | Postoperative hungry bone syndrome in patients with secondary hyperparathyroidism of renal origin显示文摘 | Goldfarb M Gondek SS Lira SM | 2012 | World J Surg2012，36，6： | 1 |
| 16 | Bregman iterative algorithm for l, minimization with applications to compressed sensing 显示文摘 | YIN W OSHER S GOLDFARB D | 2008 | SIAM J Imaging Sciences2008，1，1： | 1 |
| 17 | Use of hemodialysis and hemoperfusion in poisoned patients 显示文摘 | Holubek WJ Hoffman RS Goldfarb DS | 2008 | Kidney Int2008，74，10： | 1 |
| 18 | Combined antioxidant treatment effects on blood oxidative stress after eccentric exercise显示文摘 | GOLDFARB A H BOLLMER R J MCKENZIE M J | 2005 | Med Sci Sports Exe2005，37，2： | 1 |
| 19 | Structure and function of nucleus-vacuole junctions: outer-nuclear-membrane targeting of Nvjlp and a role in tryptophan uptake显示文摘 | Kvam E Goldfarb D S | 2006 | J Cell Sci2006，119，17： | 1 |
| 20 | Nomograms for predict-ing graft function and survival in living donor kidney transplantation based on the UNOS Registry显示文摘 | Tiong HY Goldfarb DA Kattan MW | 2009 | J Urol2009，181，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员