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2篇 您的检索式:作者名="Yusuke Tanoue"
    题名 作者 年代 出处 被引量
1Primary site resection is superior for incurable metastatic colorectal cancer显示文摘AIM:To investigate survival in patients treated with FOLFOX followed by primary site resection or palliative surgery for incurable metastatic colorectal cancer. METHODS:Between 2001 and 2009,a total of 98 patients with colorectal adenocarcinoma and non-resectable metastases were diagnosed and treated with the new systemic agent chemotherapy regimen FOLFOX. Primary site resection was carried out in 38 patients, creation of a colostomy or bypass without resection was carried out in 36 patients,and 23 were not operated on because of advanced disease.The survival times of patients in different groups were analyzed. RESULTS:There were no differences between the patients regarding their general condition,concurrent disease,or tumor stage according to AJCC classification.The median survivals of the three groups were 30.6,20.8,and 12.7 mo(log-rank P value<0.05),respectively.The postoperative complication rate was higher in the primary site resection group than in the palliative surgery group. CONCLUSION:The results indicate that there are benefits from primary site resection for incurable metastatic colorectal cancer with systemic chemotherapy.Yusuke Tanoue Nobutaka Tanaka Yukihiro Nomura 2010World Journal of Gastroenterology2010,16,28:2
2A case report of endocrine cell carcinoma in the sigmoid colon with inferior mesenteric vein tumor embolism显示文摘We report a case of endocrine cell carcinoma in the sigmoid colon with inferior mesenteric vein (IMV) tumor embolism. A 79-year-old woman was admitted to our hospital with narrowing of the stools. We performed colonoscopy, computed tomography and positron emission tomography, which disclosed sigmoid colon cancer with IMV tumor embolism. She underwent sigmoidectomy and lymph node dissection. The tumor was diagnosed as endocrine cell carcinoma (type 4, pSS, med, INFα, v3, n1, stage chromographin A, synaptophysin, cytokeratin 20 and mucicarmine showed partial staining, and CD56 was totally reactive. Three months after operation multiple liver metastases appeared. She was treated with chemotherapy of cisplatin (CDDP) + irinotecan (CPT11). This case highlights the aggressiveness of endocrine cell carcinoma with tumor embolism, and it is essential to establish an accurate diagnosis and effective treatment.Yusuke Tanoue Nobutaka Tanaka Yoshio Suzuki Shoujirou Hata Aya Yokota 2009World Journal of Gastroenterology2009,15,2:0
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