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| 1 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016，3，1： | 6 |
| 2 | Failed biliary cannulation: Clinical and technical outcomes after tertiary referral endoscopic retrograde cholangiopancreatography显示文摘AIM: Prospective evaluation of repeat endoscopic retrograde cholangiopancreatography (ERCP) for failed Schutz grade 1 biliary cannulation in a high-volume center. METHODS: Prospective intention-to-treat analysis of patients referred for biliary cannulation following recent unsuccessful ERCP. RESULTS: Fifty-one patients (35 female; mean age: 62.5 years; age range: 40-87 years) with previous failed biliary cannulation were referred for repeat ERCP. The indication for ERCP was primarily choledocholithiasis (45%) or pancreatic malignancy (18%). Successful biliary can- nulation was 100%. The precut needle knife sphincterotomy (NKS) rate was 27.4%. Complications occurred in 3.9% (post-ERCP pancreatitis). An identif iable reason for initial unsuccessful biliary cannulation was present in 55% of cases. Compared to a cohort of 940 nave pa-pilla patients (female 61%; mean age: 59.9 years; age range: 18-94 years) who required sphincterotomy over the same time period, there was no statistical difference in the cannulation success rate (100% vs 98%) or postERCP pancreatitis (3.1% vs 3.9%). Precut NKS use was more frequent (27.4% vs 12.7%) (P = 0.017). CONCLUSION: Referral to a high-volume center following unsuccessful ERCP is associated with high technical success, with a favorable complication rate, compared to routine ERCP procedures. | Michael P Swan Michael J Bourke Stephen J Williams Sina Alexander Alan Moss Rick Hope David Ruppin | 2011 | World Journal of Gastroenterology2011，17，45： | 6 |
| 3 | Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity显示文摘Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome.Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous chromosomes.Wild species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding efforts.As a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid potato.Nearly a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic load.The StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent manner.Knowledge of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids. | Genevieve Hoopes Xiaoxi Meng John P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.Kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers | 2022 | Molecular Plant2022，15，3： | 4 |
| 4 | Needle-knife sphincterotomy: factors predicting its use and the relationship with post-ERCP pancreatitis (with video)显示文摘 | Adam A. Bailey Michael J. Bourke Arthur J. Kaffes Karen Byth Eric Y. Lee Stephen J. Williams | 2010 | Gastrointestinal Endoscopy2010，，2： | 2 |
| 5 | EMR of large, sessile, sporadic nonampullary duodenal adenomas: technical aspects and long-term outcome (with videos)显示文摘 | Sina Alexander Michael J. Bourke Stephen J. Williams Adam Bailey Jonard Co | 2009 | Gastrointestinal Endoscopy2009，，1： | 2 |
| 6 | Factors that predict bleeding following endoscopic mucosal resection of large colonic lesions显示文摘 | A. Metz M. Bourke A. Moss S. Williams M. Swan K. Byth | 2011 | Endoscopy2011，，06： | 2 |
| 7 | Evaluating Second Life for the Collaborative Exploration of 3D Fractals显示文摘 | Bourke P | 2009 | Computers & Graphics - UK2009，33，1： | 1 |
| 8 | An Assessment of World Bauxite Deposit as Sources for Greenfield Alumi na Plant Developments显示文摘 | Bardossy G Budapest Bourke D J | 1993 | Aluminium1993，，10： | 1 |
| 9 | Detecting and reducing hospital adverse events : outcomes of the wimmera clinical risk management program显示文摘 | Wolf A Bourke J Campbell I | 2001 | MJA2001，174，： | 1 |
| 10 | Predicting outcomes following hospitali- zation for acute exacerbations of COPD 显示文摘 | Steer J Gibson GJ Bourke SC | 2010 | QJM2010，103，11： | 1 |
| 11 | Maternal health in pregnancy and intellectual disability in the offspring:a populationbased study显示文摘 | Leonard H de Klerk N Bourke J | 2006 | Ann Epidemiol2006，16，： | 1 |
| 12 | Effect of ultrasonic processing on food enzymes of industrial importance显示文摘 | DONNELL C P O TIWARI B K BOURKE P | | 0，，11： | 1 |
| 13 | Estimating allowable haemodilu- tion显示文摘 | Bourke DL Smith TC | 1974 | Anaesthesiology1974，41，6： | 1 |
| 14 | Influence of nitrogen and potassium fertilizer on growth of sweet potato (Ipomoea batatas)in Papua New Guinea显示文摘 | Bourke R M | 1985 | Field Crops Research1985，，12： | 1 |
| 15 | Finite element analysis of the plastic deformation zone and working load in equal ehannel angular ext rusion显示文摘 | Li S Bourke M A M Beyerlein I J | 2004 | Materials Science and Engineering A2004，382，12： | 1 |
| 16 | Predicting outcomes following hospitalization for acute exacerbations of COPD显示文摘 | Steer J Gibson GJ Bourke SC | 2010 | QJM2010，103，11： | 1 |
| 17 | Clinical and electrophysiological differences between patients with arrhythmogenic right ventricular dysplasia and right ventricular outflow tract taehycardia显示文摘 | O'Donnell D Cox D Bourke J | 2003 | Eur Heart J2003，24，9： | 1 |
| 18 | IgG subclass responses to pigeon intestinal mucin are related to development of pigeon fancier's lung显示文摘 | Baldwin CI Todd A Bourke SJ | 1998 | Clin Exp Allergy1998，28，： | 1 |
| 19 | Physostigmine for promethazine poisoning 显示文摘 | C|eghorn G Bourke G | 1980 | Lancet1980，2，8190： | 1 |
| 20 | Effect ofultrasonic processing on food enzymes oi industrial importance显示文摘 | C P O Donnell B K Tiwari P Bourke | 2010 | Trends in Food Science and Technology2010，21，7： | 1 |
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