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| 1 | Gut flora and bacterial translocation in chronic liver disease显示文摘增加的证据建议内脏植物群的精神错乱具有到有肝硬化的病人的实质的临床的关联。特别地,肠的细菌的增生和从肠的腔的内脏植物群的增加的细菌的易位在这个组为细菌的感染预先安排到一个增加的潜力。最近的研究建议除了他们在公开易传染的事件的致病和败血的临床的后果的角色,内脏植物群甚至当公开感染不在时贡献肝硬化的支持 inflammatory 状态。而且,内脏植物群的操作可以有利在肝脏硬化症的病人影响肝功能与更病原的潜力在损坏另外的内脏植物群种类的情况下扩充乳的酸类型的细菌的肠的内容。这里,我们在这个组考察在内脏植物群,细菌的易位,细菌的感染,支持 inflammatory cytokine 生产和肝功能之间的各种各样的相互关系的当前的概念。 | John Almeida Sumedha Galhenage Jennifer Yu Jelica Kurtovic Stephen M Riordan | 2006 | World Journal of Gastroenterology2006，12，10： | 37 |
| 2 | Hepatitis B virus molecular biology and pathogenesis显示文摘As obligate intracellular parasites,viruses need a host cell to provide a milieu favorable to viral replication.Consequently,viruses often adopt mechanisms to subvert host cellular signaling processes.While beneficial for the viral replication cycle,virus-induced deregulation of host cellular signaling processes can be detrimental to host cell physiology and can lead to virus-associated pathogenesis,including,for oncogenic viruses,cell transformation and cancer progression.Included among these oncogenic viruses is the hepatitis B virus(HBV).Despite the availability of an HBV vaccine,350-500 million people worldwide are chronically infected with HBV,and a significant number of these chronically infected individuals will develop hepatocellular carcinoma(HCC).Epidemiological studies indicate that chronic infection with HBV is the leading risk factor for the development of HCC.Globally,HCC is the second highest cause of cancer-associated deaths,underscoring the need for understanding mechanisms that regulate HBV replication and the development of HBV-associated HCC.HBV is the prototype member of the Hepadnaviridae family;members of this family of viruses have a narrow host range and predominately infect hepatocytes in their respective hosts.The extremely small and compact hepadnaviral genome,the unique arrangement of open reading frames,and a replication strategy utilizing reverse transcription of an RNA intermediate to generate the DNA genome are distinguishing features of the Hepadnaviridae.In this review,the authors provide a comprehensive description of HBV biology,summarize the model systems used for studying HBV infections,and highlight potential mechanisms that link a chronic HBV-infection to the development of HCC.For example,the HBV X protein(HBx),a key regulatory HBV protein that is important for HBV replication,is thought to play a cofactor role in the development of HBV-induced HCC,and the authors highlight the functions of HBx that may contribute to the development of HBV-associated HCC. | R.Jason Lamontagne Sumedha Bagga Michael J.Bouchard | 2016 | Hepatoma Research2016，2，1： | 19 |
| 3 | Unsupervised and semi-supervised clustering by message passing: soft-constraint affinity propagation 显示文摘 | Sumedha M L Weigt M | 2008 | The European Physical Journal B-Condensed Matter and Complex Systems2008，66，1： | 1 |
| 4 | Clustering by soft-constraint affinity propagation: Applications to gene-expression data显示文摘 | Sumedha M L Weigt M | 2007 | Bioinfor matics2007，23，20： | 1 |
| 5 | Clustering by soft- constraint affinity propagation: applications to gene- expression data显示文摘 | Leone M Sumedha Weigt M | 2007 | Bioinformatics2007，23，20： | 1 |
| 6 | Clustering by soft- constraint affinity propagation: applications to gene- expression data显示文摘 | Leone M Sumedha Weigt M | 2007 | Bioinformatics2007，23，20： | 1 |
| 7 | International trade and environmental quality: a survey显示文摘 | Sumedha Chhatre | 2000 | Ecological Economics2000，32，： | 1 |
| 8 | Unsupervised and Semi-Supervised clustering by message passing: Soft-con- straint affinity propagatio 显示文摘 | Leone M Sumedha Weight M | 2008 | The European Physical Journal B2008，66，： | 1 |
| 9 | Clustering by soft- constraint affinity propagation: applications to gen-expression data 显示文摘 | Leone M Sumedha Weight M | 2007 | Bioinformatic2007，23，20： | 1 |
| 10 | Clustering by Soft-constraint Affinity Propagation: Applications to Gene-expression Data显示文摘 | Leone M Sumedha Weigt M | 2007 | Bioinformatics2007，23，20： | 1 |
| 11 | International trade and environmental quality: a survey显示文摘 | Ravishankar Jayadevappa Sumedha Chhatre | 2000 | Ecological Economics2000，，2： | 1 |
| 12 | Functional siRNAs and miRNAs Exhibit Strand Bias显示文摘 | Anastasia Khvorova Angela Reynolds Sumedha D. Jayasena | 2003 | Cell2003，，2： | 1 |
| 13 | Paradoxical role of Id proteins in regulating tumorigenic potential of lymphoid cells显示文摘 | Sumedha Roy Yuan Zhuang | 2018 | Frontiers of Medicine2018，12，4： | 1 |
| 14 | Clustering by soft-constraint affinity propagation applications to gene-expression data显示文摘 | Michele L Sumedha Martin W | 2007 | Bioinformatics2007，23，20： | 1 |
| 15 | Unsupervised and semi-supervised clustering by message passing:soft-constraint affinity propagation 显示文摘 | Leone M Sumedha Weigt M | 2008 | The European Physical Journal B2008，66，1： | 1 |
| 16 | Assessment of copper and zinc status in hair and urine of young women descendants of NIDDM parents显示文摘 | Satish K. Taneja Monika Mahajan Sumedha Gupta Kiran Pal Singh | 1998 | Biological Trace Element Research1998，，3： | 1 |
| 17 | Postnatal outcome of congenital anomalies in low resource setting显示文摘 | Manisha Kumar Sumedha Sharma Manisha Bhagat Usha Gupta Rama Anand Archana Puri Anuradha Singh Abha Singh | 2013 | Prenat Diagn2013，，10： | 1 |
| 18 | Clustering by Soft-constraint Affinity Propagation:Applications to Gene-expression Data显示文摘 | Leone M Sumedha S Weigt M | | 0，，20： | 1 |
| 19 | Unsupervised and Semi-supervised Clustering by Message Passing:Soft-constrain Affinity Propagation显示文摘 | Lenoe M Sumedha Weigt M | | 0，，： | 1 |
| 20 | Unsupervised and semi-supervisedclustering by message passing: soft-constraint affinity propagation显示文摘 | SUMEDHA M L WEIGT M | 2008 | The European Physical Journal B2008，66，1： | 1 |
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