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| 1 | Lack of microRNA‐101 causes E‐cadherin functional deregulation through EZH2 up‐regulation in intestinal gastric cancer显示文摘 | Joana Carvalho Nicole C van Grieken Patricia M Pereira Sónia Sousa Marianne Tijssen Tineke E Buffart Bego?a Diosdado Heike Grabsch Manuel AS Santos Gerrit Meijer Raquel Seruca Beatriz Carvalho Carla Oliveira | 2012 | J Pathol2012，，1： | 3 |
| 2 | HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value – conclusions from 924 cases of two independent series显示文摘 | Heike Grabsch Shivan Sivakumar Sally Gray Helmut E. Gabbert Wolfram Müller | 2010 | Cellular Oncology (-)2010，，1： | 3 |
| 3 | Trends in treatment and overall survival among patients with proximal esophageal cancer显示文摘BACKGROUND The management of proximal esophageal cancer differs from that of tumors located in the mid and lower part of the esophagus due to the close vicinity of vital structures.Non-surgical treatment options like radiotherapy and definitive chemoradiation(CRT)have been implemented.The trends in(non-)surgical treatment and its impact on overall survival(OS)in patients with proximal esophageal cancer are unclear,related to its rare disease status.To optimize treatment strategies and counseling of patients with proximal esophageal cancer,it is therefore essential to gain more insight through real-life studies.AIM To establish trends in treatment and OS in patients with proximal esophageal cancer.METHODS In this population-based study,patients with proximal esophageal cancer diagnosed between 1989 and 2014 were identified in the Netherlands Cancer Registry.The proximal esophagus consists of the cervical esophagus and the upper thoracic section,extending to 24 cm from the incisors.Trends in radiotherapy,chemotherapy,and surgery,and OS were assessed.Analyses were stratified by presence of distant metastasis.Multivariable Cox proportional hazards regression analyses was performed to assess the effect of period of diagnosis on OS,adjusted for patient,tumor,and treatment characteristics.RESULTS In total,2783 patients were included.Over the study period,the use of radiotherapy,resection,and CRT in non-metastatic disease changed from 53%,23%,and 1%in 1989-1994 to 21%,9%,and 49%in 2010-2014,respectively.In metastatic disease,the use of chemotherapy and radiotherapy increased over time.Median OS of the total population increased from 7.3 mo[95%confidence interval(CI):6.4-8.1]in 1989-1994 to 9.5 mo(95%CI:8.1-10.8)in 2010-2014(logrank P<0.001).In non-metastatic disease,5-year OS rates improved from 5%(95%CI:3%-7%)in 1989-1994 to 13%(95%CI:9%-17%)in 2010-2014(logrank P<0.001).Multivariable regression analysis demonstrated a significant treatment effect over time on survival.In metastatic disease,median OS was 3.8 mo(95%CI:2.5-5.1)in 1989-1994,and 5.1 mo(95%CI:4.3-5.9)in 2010-2014(logrank P=0.26).CONCLUSION OS significantly improved in non-metastatic proximal esophageal cancer,likely to be associated with an increased use of CRT.Patterns in metastatic disease did not change significantly over time. | Judith de Vos-Geelen Sandra ME Geurts Liselot BJ Valkenburg-van Iersel Evelien JM de Jong Vivianne CG Tjan-Heijnen Margreet van Putten Valery EPP Lemmens Heike I Grabsch Nadia Haj Mohammad Frank JP Hoebers Chantal V Hoge Paul M Jeene Hanneke WM van Laarhoven Tom Rozema Marije Slingerland Grard AP Nieuwenhuijzen | 2019 | World Journal of Gastroenterology2019，25，47： | 2 |
| 4 | HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value – conclusions from 924 cases of two independent series显示文摘 | Heike Grabsch Shivan Sivakumar Sally Gray Helmut E. Gabbert Wolfram Müller | 2010 | Cellular Oncology . 2010 (1-2)2010，，1： | 2 |
| 5 | Concurrent analy- sis of nose and groin swab specimens by the IDI-MRSA PCR assay is comparable to analysis by individual-specimen PCR and routine culture assays for detection of colonization by methicillin-resistant Staphylococcus aureus 显示文摘 | BISHOP E J GRABSCH S A BALLARD B M | 2006 | J Clin Microbio12006，44，8： | 1 |
| 6 | HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value – conclusions from 924 cases of two independent series显示文摘 | Heike Grabsch Shivan Sivakumar Sally Gray Helmut E. Gabbert Wolfram Müller | 2010 | Cellular Oncology (-)2010，，1： | 1 |
| 7 | HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value – conclusions from 924 cases of two independent series显示文摘 | Heike Grabsch Shivan Sivakumar Sally Gray Helmut E. Gabbert Wolfram Müller | 2010 | Cellular Oncology (-)2010，，1： | 1 |
| 8 | HER-2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value- conclusions from 924 cases of two independent series 显示文摘 | Grabsch H Sivakumar S Gray S | 2010 | Cell Oncol2010，32，12： | 1 |
| 9 | Supportive expressive group therapy for women with metastatic breast cancer:survival and psychosocial outcome from a randomized controlled trial显示文摘 | Kissane DW Grabsch B Clarke DM | 2007 | Psychooneology2007，16，4： | 1 |
| 10 | Expression of DNA doublestrand break repair proteins ArM and BRCAI predicts survival in colorectal cancer显示文摘 | Grabsch H Dattani M Barker L | 2006 | Clin Cancer Res2006，12，5： | 1 |
| 11 | HER2 expression in gastric cancer:Rare,heterogeneous and of no prognostic value-conclusions from 924 cases of two independent series显示文摘 | Grabsch H Sivakumar S Gray S | | 0，，1： | 1 |
| 12 | Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer 显示文摘 | Hou Q Wu YH Grabsch H | 2008 | Cancer Res2008，68，： | 1 |
| 13 | HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value -conclusions from 924 cases of two independent series 显示文摘 | Grabsch H Sivakumar S Gray S | 2010 | Cell Oncol2010，32，12： | 1 |
| 14 | HER2 expression in gastric cancer:Rare,heterogeneous and of no prognostic value-conclusions from 924 cases of two independent series显示文摘 | Grabsch H Sivakumar S Gray S | 2010 | Cell Oncol2010，32，12： | 1 |
| 15 | HER2 expression in gastric Cancer: Rare, heterogeneous and of no prognostic value - conclusions from 924 cases of two Independent series 显示文摘 | Grabsch H Sivakumar S Gray S | 2010 | Cell Oncol2010，32，12： | 1 |
| 16 | Psychological morbidity and quality of life in women with advanced breast cancer: a cross -sectional survey显示文摘 | Grabsch B Clarke DM Love A | 2006 | Palliat Support Care2006，4，1： | 1 |
| 17 | HER2 expression in gastric cancer: rare, heterogeneous and of no prognostic val- ue-conclusions from 924 cases of two independent series显示文摘 | Grabsch H Sivakumar S Gray S | 2010 | Cell Oncol2010，32，12： | 1 |
| 18 | HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value- conclusions from 924 cases of two independent series显示文摘 | Grabsch H Sivakumar S Gray S | 2010 | Cell Oncol2010，32，12： | 1 |
| 19 | Screening for depressionin women with metastatic breast cancer : A comparison of theBeck Depression Inventory Short Form and the Hospital Anxietyand Depression Scale显示文摘 | Love AW?Grabsch B Clarke DM ef al | 2004 | Aust N Z J Psychiatry2004，38，7： | 1 |
| 20 | HER2 expression in gastric cancer: rare, heterogeneous and of no prognostic, value-conclusions from 924 cases of two independent series显示文摘 | Grabsch I-I Sivakumar S Gray S | 2010 | Cell Oncol2010，32，12： | 1 |
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