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| 1 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 2 | Electrolyte and current collector designs for stable lithium metal anodes显示文摘With the increasing demand for high energy-density batteries for portable electronics and large-scale energy storage systems,the lithium metal anode(LMA)has received tremendous attention because of its high theoretical capacity and low redox potential.However,the commercial application of LMAs is impeded by the uncontrolled growth of lithium dendrites.Such dendrite growth may result in internal short circuits,detrimental side reactions,and the formation of dead lithium.Therefore,the growth of lithium metal must be controlled.This article summarizes our recent efforts in inhibiting such dendrite growth,decreasing the detrimental side reactions,and elongating the LMA lifespan by optimizing the electrolyte structure and by designing appropriate current collectors.After identifying that the unstable solid electrolyte inter-face(SEI)film is responsible for the potential dropping in carbonate electrolytes,we developed LiPF_(6)-LiNO_(3) dual-salt electrolyte and lithium bis(fluorosulfonyl)imide(LiFSI)-carbonate electrolyte to stabilize the SEI film of LMAs.In addition,we achieved controlled lithium depos-ition by designing the structure and material of the current collectors,including selective lithium deposition in porous current collectors,lithio-philic metal guided lithium deposition,and iron carbide induced underpotential lithium deposition in nano-cavities.The limitations of the cur-rent strategies and prospects for future research are also presented. | Simeng Zhang Gaojing Yang Xiaoyun Li Yejing Li Zhaoxiang Wang Liquan Chen | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，5： | 2 |
| 3 | A composite of Ni-Fe-Zn layered double hydroxides/biochar for atrazine removal from aqueous solution显示文摘This study assembled corn stalk-derived biochar(BC)with layered double hydroxide(LDH)through a rapid coprecipitation of biochar and metal(Ni/Fe/Zn)hydroxide precipitates.A BC and LDH composite(BC-LDH)and modified BC-LDH material after heating(BC-LDH-P)were prepared successfully for atrazine adsorptive removal.The physicochemical properties of the synthesized samples were analyzed by X-ray diffraction(XRD),scanning electron microscopy(SEM),Fourier transform infrared(FT-IR),and X-ray photoelectron spectroscopy(XPS).Batch experiments were conducted to study the sorption of atrazine onto BC,BC-LDH,and BC-LDH-P from the aqueous solution.The adsorption of atrazine onto BC-LDH and BC-LDH-P were performed following with the pseudo-second-order kinetic model,and the sorption isotherms agreed well with the Freundlich fitting model.The adsorption amounts of the three materials are arranged in descending order is as follows:BC-LDH-P>BC-LDH>BC(143.15>123.10>95.93 mg g−1,respectively).Due to the high crystallinity of the LDH material and the high binding degree with biochar,Ni/Fe/Zn-LDH biochar composites offer a potential alternative to a carbon-based adsorbent for atrazine removal from aqueous solution. | Yifan Wang Jiaming Kang Simeng Jiang Hui Li Zheyi Ren Qinbo Xu Qun Jiang Wenzhu Liu Ruizhen Li Ying Zhang | 2020 | Biochar2020，2，4： | 2 |
| 4 | Characteristics of fungal community structure during the decomposition of mixed foliage litter from Pinus massoniana and broadleaved tree species in southwestern China显示文摘针叶树凋落物相当顽强且养分含量低,而阔叶凋落物通过增加可降解养分和促进微生物代谢来促进针叶凋落物的分解。马尾松(Pinus massoniana)凋落物和三个阔叶凋落物混合可能会增加真菌分解者的多样性和丰富性,并且会随着阔叶树种的数量和比例而有所差异。我们使用高通量测序技术分析了西南地区马尾松与香椿(Toona sinensis),香樟(Cinnamomum camphora)和檫木(Sassafras tzumu)凋落叶混合分解过程中的真菌群落组成和多样性,共设置35种实验处理。研究结果表明,与单一凋落叶相比,除马尾松+香椿,马尾松+檫木+香椿和马尾松+檫木+香樟组合中马尾松凋落叶占70%-80%以及马尾松+檫木+香樟+香椿组合中香椿凋落叶所占比例较小外,其余混合凋落叶均增加了真菌的多样性和丰富性。其中马尾松+香樟+香椿组合中的7:1:2的真菌多样性和丰富性显著高于其他处理。子囊菌门和担子菌门是最主要的优势门,曲霉属是最丰富的真菌群落属。一针一阔(6:4)和一针两阔(阔叶凋落叶占30%-40%)组合的凋落叶在整个分解过程中均表现出较强的协同作用,并且增加了可分解较难分解物质真菌菌群的相对丰度。可见马尾松+香樟+香椿组合中阔叶凋落物占30%-40%比例时增加了真菌的多样性,促进了针叶凋落物中难分解物质的分解。因此,香椿和香樟可能是构建马尾松混交林潜在的候选阔叶伴生树种。 | Yan Zhang Xun Li Danju Zhang Yu Qin Yang Zhou Simeng Song Jian Zhang | 2020 | Journal of Plant Ecology2020，13，5： | 1 |
| 5 | Effectiveness of dicyandiamide as a nitrification inhibitor in biochar-amended soil显示文摘Overuse of nitrogen(N) fertilizers may lead to many environmental issues via N leaching into groundwater and agricultural runoff into surface water.Biochar, a sustainable soil amendment agent, has been widely studied because of its potential to retain moisture and nutrients. However, recent studies have shown that biochar has a very limited ability to improve the retention of negatively charged nitrite(NO2-) or nitrate(NO3-). Although positively charged ammonium(NH4+) can be better held by biochar, it is usually susceptible to nitrification and can be easily transformed into highly mobile NO2- and/or NO3-.In practice, dicyandiamide(DCD) has been used to inhibit nitrification, preserving N in its relatively immobile form as NH4+. Therefore, it is likely that the effects of DCD and biochar in soils would be synergistic. In this study, the influences of biochar on the effectiveness of DCD as a nitrification inhibitor in a biochar-amended soil were investigated by combining the experimental results of incubation, adsorption isotherm, and column transport with the simulated results of different mathematical models. Biochar was found to stimulate the degradation of DCD, as the maximum degradation rate slightly increased from 1.237 to 1.276 mg kg-1 d-1 but the half-saturation coefficient significantly increased from 5.766 to 9.834 mg kg-1. Considering the fact that the availability of DCD for nitrification inhibition was continuously decreasing because of its degradation, a novel model assuming non-competitive inhibition was developed to simulate nitrification in the presence of a decreasing amount of DCD. Depending on the environmental conditions, if the degradation of DCD and NH4+ in biochar-amended soil is not significant, improved contact due to the mitigated spatial separation between NH4+and DCD could possibly enhance the effectiveness of DCD. | Simeng LI Gang CHEN | 2020 | Pedosphere2020，30，3： | 1 |
| 6 | Kinetic Limits of Graphite Anode for Fast‑Charging Lithium‑Ion Batteries显示文摘Fast-charging lithium-ion batteries are highly required,especially in reducing the mileage anxiety of the widespread electric vehicles.One of the biggest bottlenecks lies in the sluggish kinetics of the Li^(+)intercalation into the graphite anode;slow intercalation will lead to lithium metal plating,severe side reactions,and safety concerns.The premise to solve these problems is to fully understand the reaction pathways and rate-determining steps of graphite during fast Li^(+)intercalation.Herein,we compare the Li^(+)diffusion through the graphite particle,interface,and electrode,uncover the structure of the lithiated graphite at high current densities,and correlate them with the reaction kinetics and electrochemical performances.It is found that the rate-determining steps are highly dependent on the particle size,interphase property,and electrode configuration.Insufficient Li^(+)diffusion leads to high polarization,incomplete intercalation,and the coexistence of several staging structures.Interfacial Li^(+)diffusion and electrode transportation are the main rate-determining steps if the particle size is less than 10μm.The former is highly dependent on the electrolyte chemistry and can be enhanced by constructing a fluorinated interphase.Our findings enrich the understanding of the graphite structural evolution during rapid Li^(+)intercalation,decipher the bottleneck for the sluggish reaction kinetics,and provide strategic guidelines to boost the fast-charging performance of graphite anode. | Suting Weng Gaojing Yang Simeng Zhang Xiaozhi Liu Xiao Zhang Zepeng Liu Mengyan Cao Mehmet Nurullah Ateş Yejing Li Liquan Chen Zhaoxiang Wang Xuefeng Wang | 2023 | Nano-Micro Letters2023，15，11： | 1 |
| 7 | Characteristics of Partial Discharge in Oil-paper Insulated Needle Plate Electrode Model Under Composite AC-DC Voltage显示文摘Converter transformers are the core device in ultrahigh voltage direct current(UHVDC)transmission systems,and the oil-paper insulation at its rectifying valve side deals with the composite AC-DC voltage.A detailed investigation of the partial discharge(PD)mechanism in the oil-paper insulation under the composite AC-DC voltage is,therefore,very important.The oilpaper insulated needle plate electrode simulation model for the electric field and charge distribution can be established using hydrodynamic drift-diffusion theory and bipolar charge carrier theory,and the simulation results can reflect the morphological changes of PD.The development characteristics of PD under composite AC-DC voltage are researched.In addition,the effects of simulation time,the AC-DC component proportion,and model parameters on PD are also explored.Results indicate that differences in applied voltage,interface charge,and geometry structure can cause changes in the electric field strength,which consequently influences the PD process in the simulation model.Oil-immersed paperboard is a type of liquid-immersed dielectric(LID).When the LID is arranged in perpendicular,only the positive streamers have narrow channels oriented toward the LID.When the LID is arranged in parallel,the PDs are in the form of creeping discharges and the negative streamers are more dispersed.The development characteristics of PD and its influencing factors reported here may provide theoretical and simulation support to explain the physical mechanism of PD at the rectifying valve side of the converter transformer. | Hongshun Liu Zhitong Xue Simeng Li Qingquan Li Dongxin He Tian Xia Jian Guo | 2020 | CSEE Journal of Power and Energy Systems2020，6，4： | 1 |
| 8 | Evolution of pore fluid of low porosity and permeability reservoir in Qinnan Sag:a case study of 29-2 structurein Qinhuangdao area显示文摘The southeast depression of Qinnan Sag is a potential oil-gas exploration region in the Bohai Sea area. With the analysis of large quantity of rock thin sections,scanning electron microscope and the physical property data of reservoir,the authors studied the petrological characteristics and the evolution of pore and fluid of sandstone in the deeper strata in 29-2 structure in Qinhuangdao area. The results show that the evolutionary tendency of Paleogene sandstone reservoir porous fluid in research area is changed from alkaline porous fluid to acidic porous fluid,and back to alkaline porous fluid. There are three stages of reservoir porous evolution in Qinhuangdao area,namely sharp decrease in porosity due to mechanical compaction,increase in porosity because of corrosion and dissolution,and remarkable reduction owing to carbonate cementation. | XU Simeng PENG Xiaolei LIU Na LIU Li WANG Qingbin LIU Xiaojian JIN Xiaoyan | 2017 | Global Geology2017，20，2： | 1 |
| 9 | Epidemiological Characteristics of Influenza A and B in Macao,2010–2018显示文摘Influenza is one of the major respiratory diseases in humans.Macao is a tourist city with high density of population and special population mobility.The study on the epidemiological characteristics of influenza in Macao should bring great value for preventing influenza in tourist cities like Macao in the world.In this study,we collected a total of 104,874 samples with influenza-like illness(ILI)in Macao from 2010 to 2018.Chi-square test and binary multivariable logistic regression were used to investigate the epidemiological characteristics of influenza A and B in Macao.Among these ILI samples,the overall positive rate is 17.17%for influenza A and 6.97%for influenza B.The epidemics of influenza in three years(i.e.,2012,2017 and 2018)differ from the remaining years(i.e.,normal years).In a normal year,influenza A occurs year-round whereas influenza B is seasonal.Our research shows significant differences in influenza infections between different age groups in normal years.Interestingly,our analysis shows no significant difference between locals and tourists in influenza A and B infection in a normal year,whereas the odds of influenza A in tourists were significantly higher than those in locals in July 2017 and the odds of influenza B in tourists were significantly higher than those in locals in January–February 2012 and January–February 2018.This is possibly attributed by the policy of free vaccination to everyone in Macao.These findings should be valuable for preventing influenza in not only Macao but also the world. | HoiMan Ng Teng Zhang Guoliang Wang SiMeng Kan Guoyi Ma Zhe Li Chang Chen Dandan Wang MengIn Wong ChioHang Wong Jinliang Ni Xiaohua Douglas Zhang | 2021 | Virologica Sinica2021，36，5： | 1 |
| 10 | Properties and Hydration Mechanism of Cementitious Materials Prepared from Calcined Coal Gangue显示文摘The preparation of cementitious materials by replacing part of the cement with activated coal gangue is of great significance to the cement industry in terms of carbon reduction and coal-based solid waste utilization.For this paper,cementitious material was prepared by firing activated coal gangue under suspension conditions and batching it with limestone powder using Inner Mongolia coal gangue as raw material.The optimal ratio was determined by testing the strength changes of the cementitious material at 3,7,and 28 days of hydration,and the hydration process and mechanism were explored by combining the pore structure,heat of hydration,chemical composition,phase composition,and microscopic morphological characteristics of the hydration products.The results showed that the active materials formulated from activated gangue and limestone powder can be used to prepare cementitious materials with good performance at the level of 30%–50%replacement of cement.The optimal ratio was 30%replacement of cement,and the mass ratio of calcined gangue to limestone powder was 2:1.The 3 days compressive strength of this ratio was 28.8 MPa,which was only slightly lower than that of cement.However,the 28 days compressive strength of samples reached 67.5 MPa,which was much higher than that of the reference cement.In the hydration of this cementitious material,not only does the activated coal gangue react with the Ca(OH)_(2)formed by hydration to form C–S–H gel,but CaCO3 also participates in the reaction to form a new phase of carbon aluminate,and the two effects together promote the development of the later strength of the samples.This paper can provide a reference for carbon reduction in the cement production process and comprehensive utilization of coal gangue. | Zhaopeng Wang Shaowu Jiu Hui Li Kaifeng Zhang Simeng Cheng | 2023 | Journal of Renewable Materials2023，11，3： | 1 |
| 11 | “Three medicines and three formulas”in COVID-19:from bench to bedside显示文摘Chinese guideline has proven effective in the fight against coronavirus disease 2019(COVID-19)during the global spread of the epidemic.Traditional Chinese medicine(TCM)is widely recognized for its effectiveness in alleviating symptoms,inhibiting disease progress,reducing mortality,and improving the cure rate of patients with COVID-19.During the pandemic,“three medicines and three formulas”(TMTFs)stood out from hundreds of others in registered clinical studies,which became highly recommended as TCM for COVID-19 treatment.The TMTFs not only effectively relieve the clinical symptoms of fever,cough,fatigue,and phlegm,but also substantially shorten the time of nucleic acid negative conversion,improve lung computed tomography imaging features and inflammation,ameliorate clinical biochemical indicators,and reduce sequelae.Their potential pharmacological mechanisms are mainly related to the crosstalk between viral toxicity,endothelial damage,cytokine storm,immune response,and microthrombus.In brief,the clinical effects and the potential mechanisms of TMTFs on COVID-19 were systematically analyzed and summarized covering the entirety of disease development,including virus invasion and replication,immune response and cytokine storm,and acute respiratory distress syndrome and multiple organ dysfunction syndrome.This review provides a theoretical basis and reference for the in-depth understanding of the positive role of TMTFs in COVID-19 treatment. | Guangxu Xiao Simeng Wang Ruijiao Wang Li Tan Shibo Ma Shuang He Guanwei Fan Yan Zhu Ming Lyu | 2023 | Acupuncture and Herbal Medicine2023，3，4： | 1 |
| 12 | Evaluation of meteorological predictions by the WRF model at Barrow, Alaska and Summit, Greenland in the Arctic in April 2019显示文摘Accurate meteorological predictions in the Arctic are important in response to the rapid climate change and insufficient meteorological observations in the Arctic.In this study,we adopted a high-resolution Weather Research and Forecasting(WRF)model to simulate the meteorology at two Arctic stations(Barrow and Summit)in April 2019.Simulation results were also evaluated by using surface measurements and statistical parameters.In addition,weather charts during the studied time period were also used to assess the model performance.The results demonstrate that the WRF model is able to accurately capture the meteorological parameters for the two Arctic stations and the weather systems such as cyclones and anticyclones in the Arctic.Moreover,we found the model performance in predicting the surface pressure the best while the performance in predicting the wind the worst among these meteorological predictions.However,the wind predictions at these Arctic stations were found to be more accurate than those at urban stations in mid-latitude regions,due to the differences in land features and anthropogentic heat sources between these regions.In addition,a comparison of the simulation results showed that the prediction of meteorological conditions at Summit is superior to that at Barrow.Possible reasons for the deviations in temperature predictions between these two Arctic stations are uncertainties in the treatments of the sea ice and the cloud in the model.With respect to the wind,the deviations may source from the overestimation of the wind over the sea and at coastal stations. | ZHANG Tong CAO Le LI Simeng WANG Jiandong | 2023 | Advances in Polar Science2023，34，4： | 0 |
| 13 | Rural Development Transformation and Social Governance from the Perspective of Specialization:A Case Study of Ruiling Village in Guangzhou City,China显示文摘The reorganization of the global production network and the increased mobility of urban-rural elements have accelerated the differentiation of rural spaces,resulting in a trend towards specialization in rural areas.This paper focuses on the concept of specialization,and takes a renowned bonsai specialized village in Guangzhou City,China as a typical case to explore its transformation and development process,action logic and coupling mechanism with the social governance.The results show that:1)the development of rural specialization in Ruiling Village is shaped by several key actors,such as local governments,grassroots organizations,villagers,social organizations,policies,markets and infrastructure.The transfer of these key actors and the reconstruction of actor-networks in different stages have an important influence on the transformation and realization of rural development goals.2)Through subjects-driven,organization management and resource connection,social governance supports the specialization of rural industrial organization,operation,technology and mode.The governance structure shifts from decentralization to networking,refinement and integration.A coupling community of social governance and specialization is created by the social governance system of‘local government-grassroots organizationseconomic cooperatives-villagers’,which links industries,industrial chains and cooperatives.3)Social governance integrates into the value chain extension process of rural specialized development with a central,multi-level organizational structure.It promotes the construction of the whole value chain through organizational planning,resource integration and image shaping,thus realizing the value,branding and organization of the industry,as well as the integration of rural sustainable development and governance mechanism.Social governance has a profound impact on the development of rural specialization in terms of subject,structure and mode,and participates in the construction of the whole value chain of rural areas.This paper provides a new perspective for understanding the coupling effect of social governance in the rural development transformation,and promotes the rural sustainable development and governance. | LIN Yuancheng YANG Ren LI Simeng | 2023 | Chinese Geographical Science2023，33，5： | 0 |
| 14 | Dietary zero-dimensional fullerene supplementation improves the meat quality,lipid metabolism,muscle fiber characteristics,and antioxidative status in finishing pigs显示文摘With the increasing demand for high-quality pork,more nutritional substances have been studied for the regulation of meat quality.Zero-dimensional fullerenes(C60)can modulate the biological behavior of a variety of cell lines and animals.In this study,we report the biological effects of C60 on finishing pigs at different concentrations.A total of 24 barrows(Duroc×Large White×Landrace),with an average body weight of 21.01±0.98 kg,were divided into 3 groups and each treated daily with C60(100 or 200 mg per kg feed)or a control diet until the end of the experiment.Our results showed that dietary C60 supplementation improved flesh color,marbling scores,and flavor amino acid contents of longissimus dorsi(LD)of growing-finishing pigs(P<0.05).C60 improved meat quality by regulating lipid metabolism and muscle fiber morphology by mediating the expression of genes,L-lactic dehydrogenase(LDH),myosin heavy chain(MyHC)IIa,MyHCIIb,peroxisome proliferator-activated receptor γ(PPARγ),and fatty acid transport protein 1(FATP1)(P<0.05).Moreover,C60 substantially promoted the mRNA expression of antioxidant enzyme genes(P<0.05),which also contributed to improving meat quality.These findings have important implications for the application of C60 in the livestock industry,especially for improving the meat quality of fattening pigs. | Simeng Liao Guang Liu Bie Tan Ming Qi Xin Wu Jianjun Li Xiaoqing Li Changfeng Zhu Jiamei Huang Shuo Zhang Yulong Tang Yulong Yin | 2022 | Animal Nutrition2022，，4： | 0 |
| 15 | Somatic Embrygenesis of Symplocos paniculata显示文摘[Objectives]This study was conducted to provide a new way for the rapid reproduction of Symplocos paniculata.[Methods]With mature embryos of S.paniculata as explants,through the study of somatic embryogenesis,the effects of different media on the induction and differentiation of S.paniculata somatic embryos were discussed,and the somatic embryogenesis system for S.paniculata was preliminarily established.[Results]Calli suitable for somatic embryogenesis could be induced using modified MS(referred to as GMS)as the basic medium with the addition of 0.2 mg/L 6-BA and 0.1 mg/L NAA;the best medium combination for somatic embryo differentiation was GMS+0.25 mg/L 6-BA+0.15 mg/L NAA,and the differentiation rate could reach 71.99%;and plant regeneration needed to be carried out at low sugar concentrations.[Conclusions]This study provides a technical basis for resources protection,genetic transformation,artificial seed production,and large-scale development and utilization of S.paniculata. | Yan YANG Lijuan JIANG Changzhu LI Beilei XIE Wenjun LI Qiang LIU Simeng LI | 2022 | Agricultural Biotechnology2022，11，4： | 0 |
| 16 | Three New Species of Diploderma Hallowell, 1861 (Reptilia: Squamata: Agamidae) from the Shaluli Mountains in Western Sichuan, China显示文摘In recent years,taxonomic research of the genus Diploderma has made great progress,but there are still areas lacking relevant investigations.During 2020-2021,we carried out survey of reptile diversity in and around the Shaluli Mountains and collected some specimens of Diploderma.Of which,based on systematics inferred from mitochondrial ND2 gene sequence and morphological data,three new species were recognized:Diploderma daochengense sp.nov.from the Shuiluo River and Muli River valleys in southeastern Daocheng County,D.xinlongense sp.nov.from the upper-middle valleys of the Yalong River in Xinlong County,and D.kangdingense sp.nov.from the Yalong River middle valley and Liqiu River valley.Specifically,these three new species formed three monophyletic lineages with strongly supported and nested into the subclade I of the Bayesian and Maximum Likelihood trees.The uncorrected mean genetic distance between these new species and their closely related species was 4.3%(D.xinlongense sp.nov.vs.D.panchi),3.4%(D.daochengense sp.nov.vs.D.yulongense)and 5.5%(D.kangdingense sp.nov.vs.D.bowoense),higher than many pairs of species of Diploderma.With respect to the morphology,D.daochengense sp.nov.can be easily diagnosed from D.yulongense byhaving smoothupper edge of the dorsolateral stripes,cyan or dark olive green to yellow gular spots inbothsexes and light yelloworwhite ventrolateral body in males;D.xinlongense sp.nov.can be easily diagnosed from D.panchi by having cyan gular spot in both sexes;D.kangdingense sp.nov.can be easily diagnosed from D.bowoense by having more T4S 20-25(average 23),more F4S 16-20(average 17)and yellow to light yellow ventrolateral body,yellow gular spot present in males.To date,the number of species of the genus Diploderma has increased to 40,of which 37 species have been known in China. | Bo CAI Meihua ZHANG Jing LI Simeng DU Feng XIE Mian HOU Huaming ZHOU Jianping JIANG | 2022 | Asian Herpetological Research2022，13，4： | 0 |
| 17 | Dietary resistant starch ameliorating lipopolysaccharide-induced inflammation in meat ducks associated with the alteration in gut microbiome and glucagon-like peptide 1 signaling显示文摘Background:Consumption of resistant starch(RS)has been associated with various intestinal and systemic health benefits,but knowledge of its effects on intestinal health and inflammatory response in stressed birds is limited.Here,we examined how dietary RS supplementation from 12%raw potato starch(RPS)modulated inflammatory severity induced by lipopolysaccharide(LPS)in meat ducks.Results:LPS administration at 14,16,and 18 d(chronic challenge)decreased body weight(BW)and glucagon-like peptide 1 receptor(GLP-1R)level with higher intestinal permeability and inflammation,evident by higher proinflammatory cytokine levels.Dietary 12%RPS supplementation enhanced Claudin-1 and GLP-1R expression,along with lower levels of inflammatory factors in both ileum and serum.Microbiome analysis showed that RS treatment shifted microbial structure reflected by enriched the proportion of Firmicutes,Bifidobacterium,Ruminococcus,etc.Dietary RS addition also significantly increased the concentrations of propionate and butyrate during chronic LPS challenge.Furthermore,response to acute challenge,the ducks received 2 mg/kg BW LPS at 14 d had higher concentrations of serum endotoxins and inflammatory cytokines,as well as upregulated transcription of toll like receptor 4(TLR4)in ileum when compared to control birds.Analogous to GLP-1 agonist liraglutide,dietary RS addition decreased endotoxins and inflammation cytokines,whereas it upregulated the GLP-1 synthesis related genes expression.Meanwhile,dietary RS supplementation suppressed the acute LPS challenge-induced TLR4 transcription.Conclusions:These data suggest that dietary 12%RPS supplementation could attenuate the LPS-induced inflammation as well as intestinal injury of meat ducks,which might involve in the alteration in gut microbiota,SCFAs production and the signaling pathways of TLR4 and GLP-1/GLP-1R. | Simeng Qin Weiqiang Bai Todd JApplegate Keying Zhang Gang Tian Xuemei Ding Shiping Bai Jianping Wang Li Lv Huanwei Peng Yue Xuan Qiufeng Zeng | 2022 | Journal of Animal Science and Biotechnology2022，13，6： | 0 |
| 18 | Rapid inactivation of human respiratory RNA viruses by deep ultraviolet irradiation from light-emitting diodes on a high-temperatureannealed AlN/Sapphire template显示文摘Efficient and eco-friendly disinfection of air-borne human respiratory RNA viruses is pursued in both public environment and portable usage.The AlGaN-based deep ultraviolet(DUV)light-emission diode(LED)has high practical potentials because of its advantages of variable wavelength,rapid sterilization,environmental protection,and miniaturization.Therefore,whether the emission wavelength has effects on the disinfection as well as whether the device is feasible to sterilize various respiratory RNA viruses under portable conditions is crucial.Here,we fabricate AlGaN-based DUV LEDs with different wavelength on high-temperature-annealed(HTA)AlN/Sapphire templates and investigate the inactivation effects for several respiratory RNA viruses.The AlN/AlGaN superlattices are employed between the template and upper n-AlGaN to release the strong compressive stress(SCS),improving the crystal quality and interface roughness.DUV LEDs with the wavelength of 256,265,and 278 nm,corresponding to the light output power of 6.8,9.6,and 12.5 mW,are realized,among which the 256 nm-LED shows the most potent inactivation effect in human respiratory RNA viruses,including SARS-CoV-2,influenza A virus(IAV),and human parainfluenza virus(HPIV),at a similar light power density(LPD)of~0.8 mW/cm2 for 10 s.These results will contribute to the advanced DUV LED application of disinfecting viruses with high potency and broad spectrum in a portable and eco-friendly use. | Ke Jiang Simeng Liang Xiaojuan Sun Jianwei Ben Liang Qu Shanli Zhang Yang Chen Yucheng Zheng Ke Lan Dabing Li Ke Xu | 2023 | Opto-Electronic Advances2023，6，9： | 0 |
| 19 | The Clinical Application Value of Selective Unifocalization in the Treatment of Severe Pulmonary Artery Atresia with Ventricular Septal Defect显示文摘Background:This study aims to explore the efficacy of selective unifocalization(UF)for major aortopulmonary collateral arteries(MAPCAs)unifocalization in children with pulmonary atresia with ventricular septal defect(PA/VSD).Methods:A retrospective analysis of 13 patients with PA/VSD/MAPCAs who underwent surgery from June 2017 to December 2019.Sex,age,preoperative cardiovascular angiography test results and McGoon ratio were collected.The properties of the collateral arteries were evaluated by angiography,and selective UF for the“dendritic”MAPCAs and ligation of MAPCAs demonstrating distortion and resistance.Results:A total of 13 severe patients underwent one-stage repair,of which 1 case underwent ventricular septal fenestration and died after 2 weeks of ECMO support.The median age was 37 months,and a median weight was 14.0 kg.A right ventricular to aortic systolic pressure ratio(pRV/pAo)of no more than 0.5 was achieved in 12 living patients.Conclusion:Selective unifocalization based on MAPCAs morphology can achieved a good outcome at the early stage.This surgical concept might be provided a novel insight into treatment for some of the subgroups presenting with this complex form of PA/VSD/MAPCAs. | Jinyang Liu Bo Peng Xianchao Jiang Simeng Zhang Jiachen Li Lizhi Lv Qiang Wang Xiang Li | 2021 | Congenital Heart Disease2021，16，1： | 0 |
| 20 | Effects of hydrological and climatic variables on cyanobacterial blooms in four large shallow lakes fed by the Yangtze River显示文摘Shallow lakes,one of the most widespread water bodies in the world,are easily shifted to a new trophic state due to external interferences.Shifting hydrologic conditions and climate change can cause cyanobacterial harmful algal blooms(CyanoHABs)in shallow lakes,which pose serious threats to ecological integrity and human health.This study analyzed the effects of hydrologic and meteorological variables on cyanobacterial blooms in Yangtze-connected lakes(Lake Dongting and Poyang)and isolated lakes(Lake Chao and Tai).The results show that(i)chlorophyll-a(Chl-a)concentration tends to decrease exponentially with increasing relative lake level fluctuations(RLLF)and precipitation,but to increase linearly with increasing wind speed and air temperature;(ii)Chl-a concentrations in lakes were significantly higher when RLLF<100,precipitation<2.6 mm,wind speed>2.6 ms^(-1),or air temperature>17.8℃;(iii)the Chl-a concentration of Yangtze-isolated lakes was more significantly affected by water level amplitude,precipitation,wind speed and air temperature than the Yangtze-connected lakes;(iv)the RLLF and the ratio of wind speed to mean water depth could be innovative coupling factors to examine variation characteristics of Chl-a in shallow lakes with greater correlation than single factors. | Jian Huang Qiujin Xu Xixi Wang Hao Ji Edward J.Quigley Mohamadali Sharbatmaleki Simeng Li Beidou Xi Biao Sun Caole Li | 2021 | Environmental Science and Ecotechnology2021，，1： | 0 |
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