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| 1 | Development of Epstein-Barr virus-associated gastric cancer:Infection,inflammation,and oncogenesis显示文摘Epstein-Barr virus(EBV)-associated gastric cancer(EBVaGC)cells originate from a single-cell clone infected with EBV.However,more than 95%of patients with gastric cancer have a history of Helicobacter pylori(H.pylori)infection,and H.pylori is a major causative agent of gastric cancer.Therefore,it has long been argued that H.pylori infection may affect the development of EBVaGC,a subtype of gastric cancer.Atrophic gastrointestinal inflammation,a symptom of H.pylori infection,is observed in the gastric mucosa of EBVaGC.Therefore,it remains unclear whether H.pylori infection is a cofactor for gastric carcinogenesis caused by EBV infection or whether H.pylori and EBV infections act independently on gastric cancer formation.It has been reported that EBV infection assists in the oncogenesis of gastric cancer caused by H.pylori infection.In contrast,several studies have reported that H.pylori infection accelerates tumorigenesis initiated by EBV infection.By reviewing both clinical epidemiological and experimental data,we reorganized the role of H.pylori and EBV infections in gastric cancer formation. | Hisashi Iizasa Andy Visi Kartika Sintayehu Fekadu Shunpei Okada Daichi Onomura Afifah Fatimah Azzahra Ahmad Wadi Mosammat Mahmuda Khatun Thin Myat Moe Jun Nishikawa Hironori Yoshiyama | 2022 | World Journal of Gastroenterology2022，28，44： | 3 |
| 2 | Light and Scanning Electron Microscope Examination of the Digestive Tract in Peppered Moray Eel, G ymnothorax pictus ( E lopomorpha)显示文摘 | Shunpei Takiue Hideo Akiyoshi | 2013 | Anat Rec2013，，3： | 1 |
| 3 | Effects of cooling rate on microstructures and magnetic properties of Nd-Fe-B alloys 显示文摘 | Shunpei Ozawa Tetsuji Saito Tetsuichl Motegi | 2004 | Journal of Alloys and Compounds2004，363，12： | 1 |
| 4 | On the age and growth of Nibea albiflora显示文摘 | SHUNPEI K KAZUO N | 1980 | Bulletin of the Japanese society of Scientific Fisheries1980，46，2： | 1 |
| 5 | Effects of cooling rate on microstructures and magnetic properties of Nd-Fe-B alloys显示文摘 | Shunpei Ozawa Tetsuji Saito Tetsuichi Motegi | 2004 | Journal of alloys and compounds2004，363，： | 1 |
| 6 | Flame synthesis of carbon nanotubes in a wall stagnation flow显示文摘 | Nakazawa Shunpei Yokomori Takeshi Mizomoto Masahiko | 2005 | Chemical Physics Letters2005，403，： | 1 |
| 7 | Co-methanation of carbon monoxide and carbon dioxide on supported nickel and cobalt catalysts prepared from amorphous alloys显示文摘 | Hiroki Habazaki Michiaki Yamasaki Bo-Ping Zhang Asahi Kawashima Shunpei Kohno Takuro Takai Koji Hashimoto | 1998 | Applied Catalysis A General1998，，1： | 1 |
| 8 | Factors Predictive of Adverse Events Associated with Endoscopic Ultrasound-Guided Fine Needle Aspiration of Pancreatic Solid Lesions显示文摘 | Akio Katanuma Hiroyuki Maguchi Kei Yane Shunpei Hashigo Toshihumi Kin Maki Kaneko Shin Kato Ryusuke Kato Ryo Harada Manabu Osanai Kuniyuki Takahashi Masanori Nojima | 2013 | Digestive Diseases and Sciences2013，，7： | 1 |
| 9 | Com- parison of Bullet Formation from Twin Scales and Single Scales in Hippeastrum hybridum Cultured in Vitro显示文摘 | Chih Wei Huang Hiroshi Okubo Shunpei Uemoto | 1990 | Scientia Horticulturae1990，42，12： | 1 |
| 10 | Effect of cooling rate on microstructures and magnets properties of Nd-Fe-B alloys显示文摘 | Testuji Satito | 2004 | Alloys and compounds2004，，363： | 1 |
| 11 | Natural Killer T Cells Are Involved in Adipose Tissues Inflammation and Glucose Intolerance in Diet-Induced Obese Mice显示文摘 | Kazue Ohmura Naoki Ishimori Yoshinori Ohmura Satoshi Tokuhara Atsushi Nozawa Shunpei Horii Yasuhiro Andoh Satoshi Fujii Kazuya Iwabuchi Kazunori Onoé Hiroyuki Tsutsui | 2010 | Arteriosclerosis Thrombosis and Vascular Biology2010，，2： | 1 |
| 12 | On the maturity and spawning of Nibea albiflora 显示文摘 | SHUNPEI K KAZUO N | 1981 | Bulletin of the Japanese Society of Scientific Fisheries1981，47，1： | 1 |
| 13 | Rhizome induction and plantlet regeneration of Cymbidium goeringii from flower bud cultures in vitro显示文摘 | Kazuhiko Shimasaki Shunpei Uemoto | 1991 | Plant Cell, Tissue and Organ Culture1991，，1： | 1 |
| 14 | Fluidization behavior of glass beads under different vibration modules显示文摘 | Tao Zhou Hiroyuki Kage Shunpei Funaoka Hironao Ogura Yoshizo Matsuno | 2001 | Advanced Powder Technology2001，，4： | 1 |
| 15 | Prospective study of mother-to-infant transmission of hepatitis C virus显示文摘 | HITOSHI TAJIRI YOKO MIYOSHI SHUNPEI FUNADA YURI ETANI JIRO ABE TAKASHI ONODERA MEGUMI GOTO MASAHISA FUNATO SHINOBU IDA CHIEKO NODA MASAHIRO NAKAYAMA SHINTARO OKADA | 2001 | The Pediatric Infectious Disease Journal2001，，1： | 1 |
| 16 | Involvement of A5/A7 noradrenergic neurons and B2 serotonergic neurons in nociceptive processing:a fiber photometry study显示文摘In the central nervous system,the A6 noradrenaline(NA)and the B3 serotonin(5-HT)cell groups are well-recognized players in the descending antinociceptive system,while other NA/5-HT cell groups are not well characterized.A5/A7 NA and B25-HT cells project to the spinal horn and form descending pathways.We recorded G-Ca MP6 green fluorescence signal intensities in the A5/A7 NA and the B25-HT cell groups of awake mice in response to acute tail pinch stimuli,acute heat stimuli,and in the context of a non-noxious control test,using fiber photometry with a calcium imaging system.We first introduced G-Ca MP6 in the A5/A7 NA or B25-HT neuronal soma,using transgenic mice carrying the tetracycline-controlled transactivator transgene under the control of either a dopamineβ-hydroxylase or a tryptophan hydroxylase-2 promoters and by the site-specific injection of adeno-associated virus(AAV-Tet O(3 G)-G-Ca MP6).After confirming the specific expression patterns of G-Ca MP6,we recorded G-Ca MP6 green fluorescence signals in these sites in awake mice in response to acute nociceptive stimuli.G-Ca MP6 fluorescence intensity in the A5,A7,and B2 cell groups was rapidly increased in response to acute nociceptive stimuli and soon after,it returned to baseline fluorescence intensity.This was not observed in the non-noxious control test.The results indicate that acute nociceptive stimuli rapidly increase the activities of A5/A7 NA or B25-HT neurons but the non-noxious stimuli do not.The present study suggests that A5/A7 NA or B25-HT neurons play important roles in nociceptive processing in the central nervous system.We suggest that A5/A7/B2 neurons may be new therapeutic targets.All performed procedures were approved by the Institutional Animal Use Committee of Kagoshima University(MD17105)on February 22,2018. | Shunpei Moriya Akira Yamashita Daiki Masukawa Junichi Sakaguchi Yoko Ikoma Yoshimune Sameshima Yuki Kambe Akihiro Yamanaka Tomoyuki Kuwaki | 2022 | Neural Regeneration Research2022，17，4： | 0 |
| 17 | A13 dopamine cell group in the zona incerta is a key neuronal nucleus in nociceptive processing显示文摘In stressful modern society, pain caused by physical and mental disorders is an increasing social health problem all over the world.Physical and mental activity depends on the state of various neurotransmitters in the central nervous system(CNS).Monoaminergic systems play important roles in regulating physiological functions including nociception.It is well known that in the CNS, there are descending pathways related to nociceptive processing known as the descending antinociceptive system(DAS).Noradrenalin and serotonin are major components of the DAS that form the locus coeruleus(LC)-spinal dorsal horn noradrenergic circuit and periaqueductal gray(PAG)-rostro ventricular medulla(RVM)-spinal dorsal horn serotonergic circuit(Jordan et al., 2008).Dopaminergic pathways also play roles in regulating nociceptive processing in the CNS. | Shunpei Moriya Tomoyuki Kuwaki | 2021 | Neural Regeneration Research2021，16，7： | 0 |
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