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| 1 | m^6A mRNA methylation sustains Treg suppressive functions显示文摘 | Jiyu Tong Guangchao Cao Ting Zhang Esen Sefik Maria Carolina Amezcua Vesely James P Broughton Shu Zhu Huabin Li Bin Li Lei Chen Howard Y Chang Bing Su Richard A Flavell Hua-Bing Li | 2018 | Cell Research2018，28，2： | 30 |
| 2 | 埃森创伤问卷中文版的信度和效度研究显示文摘目的对埃森大学医院心身科编制的埃森创伤问卷(ETI)进行初步的修订和信度效度检验。方法收集1120名受试者,分为心理患者组、躯体患者组、地震受灾组以及健康对照组,分别使用ETI进行测试,分析ETI中文版的信度、结构效度及效标效度。结果ETI共23个项目的总体信度克隆巴赫系数为0.94,各维度的相关性系数为0.69~0.80,提示有较好的内部一致性。因子分析得到3个因子结构(包括闯入、回避、分离);效标关联效度理想。结论修订的ETI具有较高的信度和效度。 | 周娟 周肖榕 李航 董非 王琳丽 鄢利福 刘欢 江瑞芳 余萍 邬晓艳 陈静 刘莉 Sefik Tagay Wolfgang Senf 施琪嘉 | 2010 | 中华物理医学与康复杂志2010，32，2： | 22 |
| 3 | 5·12地震后PTSD症状严重性和社会支持之间的相关性研究显示文摘目的:探讨社会支持与创伤后应激障碍(PTSD)之间的相关性。方法:地震后1年半,应用德国埃森创伤问卷(ETI)及社会支持评定问卷(SSRS),以震区454名普通群众为被试,对ETI得分和SSRS得分进行相关性分析。结果:①被试社会支持水平与PTSD整体症状水平存在显著负相关。②被试社会支持各维度的水平与PTSD各症状群均为显著负相关,但相关程度不同。负相关程度排序依次为对支持的利用度、主观支持和客观支持。结论:社会支持水平是PTSD的保护性因子,社会支持中的主观支持和支持利用度与PTSD负相关程度更明显。 | 邬晓艳 周娟 周肖榕 李航 董非 王琳丽 鄢利福 刘欢 江瑞芳 余萍 陈静 刘莉 马学尧 杨丽娟 赵莹莹 杜海英 Sefik Tagay Wolfgang Senf 施琪嘉 | 2010 | 神经损伤与功能重建2010，5，4： | 6 |
| 4 | Clinical risk factors for the development of consecutive exotropia:a comparative clinical study显示文摘AIM: To compare a group of patients with consecutive exotropia with patients who had ≤10 prism diopters(PD)esotropia or no deviation postoperatively in terms of probable clinical risk factors for the development of consecutive exotropia.METHODS: The study recruited fourteen patients who developed consecutive exodeviation during follow-up period after the correction of esotropia who were categorized as group 1 and thirty-one patients who had still ≤10 PD esotropia or no deviation at the final visit that were considered as group 2. Clinical risk factors leading the development of consecutive deviation were analyzed as the main outcome measures.RESULTS: The mean age of patients was 4.57±3.11 y in group 1 and 5.10±3.52 y in group 2(P =0.634). There was no significant difference of preoperative near and distant deviations among two groups(P =0.835, 0.928respectively). The mean amount of medial rectus recession and lateral rectus resection was similar in both groups(P =0.412, 0.648 respectively). Convergence insufficiency and neurological diseases were more frequent in group 1(P =0.007, 0.045). Accompanying neurological disease was found to be as a significant factor increasing the risk of the development of consecutive exotropia significantly [odds ratios(OR):5.75(1.04-31.93)]. CONCLUSION: Accompanying neurological disease appears to be a significant clinical risk factor for the development of consecutive exodeviation during postoperative follow-up after the correction of esotropia.However, larger studies are needed in order to interpret the results to the clinical practice and to ascertain other concurrent risk factors. | Hande Tayla Sekeroglu Kadriye Erkan Turan Jale Karakaya Emin Cumhur Sener Ali Sefik Sanac | 2016 | International Journal of Ophthalmology(English edition)2016，9，6： | 2 |
| 5 | Isolation and diagnosis of Helicobacter pylori by a new method: Microcapillary culture显示文摘AIM:To investigate the performance of the microcapillary culture method(MCM) in Helicobacter pylori(H.pylori) isolation and diagnosis.METHODS:Microcapillary culture(MC),classical culture(CC),rapid urease(CLO) test,and histopathologic examination(HE) were performed with biopsy samples.Homogenized biopsy samples were loaded into capillary tubes and incubated for 48 h at 37 ℃ without providing a microaerophilic environment.Additionally,three or four loops of the homogenized sample were inoculated in a ready-to-use selective medium(Becton Dickinson,Helicobacter Agar,Modified) specific for the isolation of H.pylori and incubated at 37 ℃ in a microaerophilic atmosphere provided by Campy Gen(Becton Dickinson,Gas Pack).Bacteria reproducing in microcapillary tubes were evaluated in an inverted microscope and also were evaluated after performing a CC with the content.Results obtained by CC,CLO test,and HE were compared with those of MC.The diagnostic performances of the methods used in this study were evaluated for specificity,sensitivity,positive predictive value(PPV),negative predictive value(NPV),and CI.RESULTS:H.pylori was found positive by CLO test +HE and/or CC culture in 26 patient antrum and corpus biopsy samples.In 25(25/26) patient biopsy samples,H.pylori was isolated by MCM,whereas in only 14(14/26) patient biopsy samples,H.pylori was isolatedby CC.CLO test and HE were found positive in 17(17/26) patient biopsy samples.Comparing the results of the isolation of H.pylori by MCM,CC,CLO test,and HE,the sensitivity of the MCM was found as 96%,the specificity as 80%,the PPV as 83%,the NPV as 95%,and the 95%CI as 0.76(χ2 =31.51,P < 0.01) whereas the sensitivity of the CC was found as 54%(χ2 =19.15,P < 0.01),and the sensitivity of the CLO test and HE were found as 65%(χ2 =25.26,P < 0.01).CONCLUSION:This new microcapillary cultivation method for H.pylori has high diagnostic sensitivity compared with CC,HE,and CLO tests. | Adil M Allahverdiyev Melahat Bagirova Reyhan Caliskan Hrisi Bahar Tokman Hayat Aliyeva Gokce Unal Olga Nehir Oztel Emrah Sefik Abamor Hilal Toptas Pelin Yuksel Fatma Kalayci Mustafa Aslan Yusuf Erzin Kadir Bal Bekir S Kocazeybek | 2015 | World Journal of Gastroenterology2015，21，9： | 2 |
| 6 | Screening Methods for High-Grade Dysplasia in Patients with Anal Condyloma 1显示文摘 | Harry T. Papaconstantinou Augustine J. Lee Clifford L. Simmang Raheela Ashfaq Sefik T. Gokaslan Saul Sokol Philip J. Huber Sharon G. Gregorcyk | 2005 | Journal of Surgical Research2005，，1： | 1 |
| 7 | Health-related quality of life,depression and anxiety in thyroid cancer patients显示文摘 | Sefik T Stephan H Matthias L | 2006 | Quality of Life Research2006，15，2： | 1 |
| 8 | Building a Robust Manufacturing Strategy 显示文摘 | Rajesh Jugulum Mustafa Sefik | 1998 | Computers Industry Engineering1998，，35： | 1 |
| 9 | Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3显示文摘 | Karen M. Lammers Ruliang Lu Julie Brownley Bao Lu Craig Gerard Karen Thomas Prasad Rallabhandi Terez Shea-Donohue Amir Tamiz Sefik Alkan Sarah Netzel–Arnett Toni Antalis Stefanie N. Vogel Alessio Fasano | 2008 | Gastroenterology2008，，1： | 1 |
| 10 | Hemicellulose extraction of mixed southern hardwood with water at 150℃ : Effect of Time显示文摘 | Tunc M Sefik Adriaan R P van Heiningen | 2008 | In- dustrial and Engineering Chemistry Research2008，47，18： | 1 |
| 11 | Two-stage fractionation and fiber production of lignocellulosic biomass for liquid fuels and chemicals显示文摘 | TUNC M Sefik CHHEDA Juben VAN DER HEIDE Evert | 2013 | I&EC Research2013，52，13： | 1 |
| 12 | Synthesis of the HSA-conjugate of the S -linked thiomimetic of the branched tetrasaccharide repeating unit of the immunostimulant polysaccharide, schizophyllan. Evaluation as potential immunomodulator显示文摘 | Yili Ding Sefik S. Alkan Gerhard Baschang Jacques Defaye | 2000 | Carbohydrate Research2000，，1： | 1 |
| 13 | The role of the bipolar plasmakinetic TURP over 100 g prostate in the elderly patients显示文摘 | Enis Rauf Coskuner Tayyar Alp Ozkan Sefik Koprulu Ozdal Dillioglugil Ibrahim Cevik | 2014 | International Urology and Nephrology2014，，11： | 1 |
| 14 | Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses显示文摘 | Nicole Joller Ester Lozano Patrick R. Burkett Bonny Patel Sheng Xiao Chen Zhu Junrong Xia Tze G. Tan Esen Sefik Vijay Yajnik Arlene H. Sharpe Francisco J. Quintana Diane Mathis Christophe Benoist David A. Hafler Vijay K. Kuchroo | 2014 | Immunity2014，，4： | 1 |
| 15 | Naturally transmitted segmented filamentous bacteria segregate w ith diabetes protection in nonobese diabetic mice显示文摘 | Kriegel MA Sefik E Hill JA | 2011 | Proc Natl Acad2011，108，11： | 1 |
| 16 | A new approach for development of vaccine against visceral leishmaniasis: Lipophosphoglycan and polyacrylic acid conjugates显示文摘Objective: To determine the antileishmanial vaccine effectiveness of lipophosphoglycan(LPG) and polyacrylic acids(PAA) conjugates on in vivo mice models.Methods: LPG molecule was isolated and purified from large-scale Leishmania donovani parasite culture. Protection efficacies of LPG alone, in combination with Freund's adjuvant, in a physical mixture and in conjugate(consisting of various LPG concentrations) with PAA, were comparatively determined by various techniques, such as cultivation with the micro-culture method, assessment of in vitro infection rates of peritoneal macrophages, determination of parasite load in liver with Leishman-Donovan Units, and detection of cytokine responses.Results: Obtained results demonstrated that the highest vaccine-mediated immune protection was provided by LPG-PAA conjugate due to all parameters investigated. According to the Leishman-Donovan Units results, the sharpest decline in parasite load was seen with a ratio of 81.17% when 35 mg LPG containing conjugate was applied. This value was 44.93% for the control group immunized only with LPG. Moreover, decreases in parasite load were 53.37%, 55.2% and 65.8% for the groups immunized with 10 mg LPG containing LPG-PAA conjugate, a physical mixture of the LPG–PAA, and a mixture of LPG + Freund's adjuvant, respectively. Furthermore, cytokine results supported that Th1 mediated protection occurred when mice were immunized with LPG-PAA conjugate.Conclusions: It has been demonstrated in this study that conjugate of LPG and PAA has an antileishmanial vaccine effect against visceral leishmaniasis. In this respect, the present study may lead to new vaccine approaches based on high immunogenic LPG molecule and adjuvant polymers in fighting against Leishmania infection. | Adil M.Allahverdiyev Rabia Cakir Koc Melahat Bagirova Serhat Elcicek Serap Yesilkir Baydar Olga Nehir Oztel Emrah Sefik Abamor Sezen Canim Ates Murat Topuzogullari Sevil Isoglu Dincer Zeynep Akdeste | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，9： | 1 |
| 17 | The effect of combined therapy with amsulosin hydrochloride and meloxicam in patients with benign prostatic hyperplasia symptoms and impact on nocturia and sleep quality 显示文摘 | Gorgel S N Sefik E Kose O | 2013 | Int Braz J Urol2013，39，5： | 1 |
| 18 | Postoperative pain in open vs laparoscopic cholecysteetomy with and without local application of anaesthetic显示文摘 | Enes H Semir I Sefik H | 2011 | Med Glas Ljek Komore Zenickodoboj Kantona2011，8，2： | 1 |
| 19 | The effect of combined therapy with tamsulosin hydrochloride and meloxicam in patients with benign prostatic byperplasia symptoms and impact on nocturia and sleep quality显示文摘 | Gorgel SN Sefik E Kose O | 2013 | Int Braz J Urol2013，39，5： | 1 |
| 20 | Antimicrobial effects of TiO2 and Ag2O nanoparticles against drug-resistant bacteria and leishmania parasites显示文摘 | Allahverdiyev Adil M Abamor Emrah Sefik Bagirova Malahat Rafailovich Miriam | 2011 | EN2011，，8： | 1 |
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