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| 1 | NAC Transcription Factor ORE1 and Senescence- Induced BIFUNCTIONAL NUCLEASE1 (BFN1) Constitute a Regulatory Cascade in Arabidopsis显示文摘老朽是包含很多抄写因素的行动的一个高度调整的过程。NAC 抄写因素 ORE1 (ANAC092 ) 最近被显示了在断然在 Arabidopsis thaliana 控制老朽起一个关键作用;然而,它通过施加它的分子的功能的直接目标基因都没以前被识别。这里,我们报导那 BIFUNCTIONAL NUCLEASE1 (BFN1 ) ,著名提高老朽的基因,被 ORE1 直接调整。我们已经检测了 BFN1 的提高的表示在在 estradiol 可诱导的 ORE1 overexpression 线的 ORE1 的正式就职以后的 2 h 和在有 35S:ORE1 的 Arabidopsis 叶肉房间原物的 transfection 以后的 6 h 构造。当在衰老的叶子和成熟的花机关的截去地区的 BFN1 表示在 ore1 异种背景是几乎不在的时, ORE1 和 BFN1 表示模式大部分重叠,由 promoterreporter 显示出基因(GUS ) 熔化。在 vitro 绑定地点试金揭示了一个由两部组成的 ORE1 有约束力的地点,类似于 ORS1 的, ORE1 的 paralog。一个由两部组成的 ORE1 有约束力的地点在 BFN1 倡导者被识别;变异在全身的 BFN1 倡导者的上下文以内的 cis 元素急速地减少了调停 ORE1 的 transactivation 能力在短暂地 transfected Arabidopsis 叶肉房间原物。而且,染色质 immunoprecipitation (薄片) 在 ORE1 有约束力的 vivo 示威到 BFN1 倡导者。我们也在 vivo 表明 ORE1 的绑定到二另外的联系老朽的基因的倡导者,也就是 SAG29/SWEET15 和 SINA1,在老朽期间支持 ORE1 的中央角色。 | Lilian R Matallana-Ramirez Mamoona Rauf Sarit Farage-Barhom Hakan Dortay Gang-Ping Xue Wolfgang Droge-Laser Amnon Lers Salma Balazadeh Bernd Mueller-Roeber | 2013 | Molecular Plant2013，6，5： | 8 |
| 2 | Synthesis and evaluation of in vitro antibacterial activity of novel 2,5-disubstituted-l,3,4-thiadiazoles from fatty acids显示文摘一系列新 1-(alkenoyl/hydroxyalkenoyl )-4-benzoyl-thiosemicarbazides 2ad 和 2-benzamide-5-alkenyl/hydroxyalkenyl-1,3,4-thiadiazoles 3ad 从丰满的酸一种肺结核特效药被综合。所有这些混合物的结构被红外, 1H NMR, 13C NMR,集体系列和元素的分析证实。生物鉴定结果显示某混合物 2c, 2d, 3c 和 3d 举办好抗菌剂活动。 | Mudasir R.Banday Abdul Rauf | 2008 | Chinese Chemical Letters2008，19，12： | 7 |
| 3 | One-pot synthesis,antibacterial and antifungal activities of novel 2,5-disubstituted-1,3,4-oxadiazoles显示文摘一系列新奇 2,5-disubstituted-1,3,4-oxadiazoles 从长链的 alkanoic 和 alkenoic 酸被综合了。这些混合物的结构被阐明了由元素、光谱(红外, 1H NMR, 13C NMR, MS ) 分析。而且,混合物被屏蔽为在对代表性的面板的 vitro 抗菌活性二克积极并且二个克否定的细菌。所有综合混合物也对真菌的五紧张为他们的抑制效应被测试。对测试有机体的各种各样的混合物表演有势力抑制效应。 | Abdul Rauf Shweta Sharma Saloni Gangal | 2008 | Chinese Chemical Letters2008，19，1： | 6 |
| 4 | DCC/DMAP mediated esterification of hydroxy and non-hydroxy olefinic fatty acids with β-sitosterol:In vitro antimicrobial activity显示文摘A new series of fatty alkenoates were synthesized using an appropriate synthetic route involving DCC and DMAP as catalysts. Compounds were characterized by their spectral data. All the synthesized compounds were evaluated for their in vitro antimicrobial activity. The minimum inhibitory concentration (MIC), minimum bacterial concentration (MBC) and minimum fungicidal concentration (MFC) were determined for test compounds as well as for reference standards. Among the compounds tested, compounds having hydroxy group at the fatty acid chain showed the most potent antibacterial as well as antifungal activities. | Nida N.Farshori Mudasir R.Banday Zeeshan Zahoor Abdul Rauf | 2010 | Chinese Chemical Letters2010，21，6： | 5 |
| 5 | Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a novel model of obesity and puberty显示文摘童年肥胖和肥胖相关的新陈代谢的复杂并发症被一本高脂肪的出生后的食谱导致。然而,一个合适的动物模型的缺乏在肥胖研究仍然是可观的挑战。在当前的学习,我们在断奶以后在哺乳期间并且到小狗提供了高脂肪的饮食(HFD ) 给水坝。我们也与导致 HFD 的出生后的肥胖开发了 C57BL/6J 老鼠小狗的一个新奇模型。结果证明用 HFD 喂在小狗导致胖免职和肥胖。而且, HFD 更 potently 比女小狗增加了男性的身体重量(BW ) 。喂 HFD 的女小狗是肥胖的,经历了早熟的发身,并且显示出在视下丘的增加的 kisspeptin 表示。然而,父母肥胖和早熟的发身没在导致 HFD 的出生后的重量获得和小狗的发身发作上施加 synergistic 效果。有趣地,有正常 BW 的一些喂 HFD 的崽也展出了早熟的发身。这发现建议了那篇食谱作文然而并非 BW 扳机发身发作。我们的模型建议肥胖和早熟的发身的好构造有效性。而且,我们的模型能也被用来探索在 dietinduced 之间的相互的相互作用出生后的童年肥胖和发身。 | Rahim Ullah Yan Su Yi Shen Chunlu Li Xiaoqin Xu Jianwei Zhang Ke Huang Naveed Rauf Yang He Jingjing Cheng Huaping Qin Yu-Dong Zhou Junfen Fu | 2017 | Frontiers of Medicine2017，11，2： | 5 |
| 6 | Simultaneous operation of dibenzothiophene hydrodesulfurization and methanol reforming reactions over Pd promoted alumina based catalysts显示文摘In the current study simultaneous reactions of hydrodesulfurization(HDS) of dibenzothiophene(DBT) and reforming of methanol in a micro-autoclave reactor were studied over bi-metallic(Co-Mo/Al2O3 and Ni-Mo/Al2O3) and tri-metallic(Pd-Co-Mo/Al2O3 and Pd-Ni-Mo/Al2O3) catalyst systems which were prepared by incipient impregnation method.In situ hydrogen utilization and low Pd loadings were the major targets of this study.For comparison purpose,catalytic activity was separately determined for both the methanol reforming and HDS of DBT reactions as well.Ni based catalysts were confirmed with better activity than Co ones for both the reactions with Pd promoted ones ranking at the top i.e.Pd-Ni-Mo/Al2O3 > Ni-Mo/Al2O3 > Pd-Co-Mo/Al2O3 > Co-Mo/Al2O3 where Pd-Ni-Mo/Al2O3 showed 91% DBT conversion at 380 ℃ and 12 h reaction time.Some of the selected organic additives on catalytic activity were tested for their effect toward HDS reaction which was unique with close relation to their chemical nature.Reaction products were quantitatively and qualitatively analyzed via HPLC and GC-MS techniques respectively which helped in elucidating reaction mechanism. | Muhammad Yaseen Muhammad Shakimllah Imtiaz Ahmad Ata Ur Rahman Faiz Ur Rahman Muhammad Usman Rauf Razzaq | 2012 | 燃料化学学报2012，40，6： | 3 |
| 7 | 联合成对学习和图像聚类的无监督肺癌亚型识别显示文摘基因诊断是近年来提高肺癌治愈率的一种新型且有效的方法,但这种方法存在基因检测时间长、费用高、侵入式取样损伤大的问题。文中提出了基于成对学习和图像聚类的无监督学习的肺癌亚型识别方法。首先,采用无监督卷积特征融合网络用于学习肺癌CT图像的深度表示,有效地捕捉被忽略的重要特征信息,并使用包含不同层次抽象信息的最终融合特征来表征肺癌亚型。然后,使用联合成对学习和图像聚类的分类学习框架进行建模,充分利用学习到的特征表示,确保有效的聚类学习,以取得更高的分类精度。最后,利用生存分析和基因分析对肺癌亚型进行多角度验证。在合作医院和TCGA-LUAD数据集上的实验结果表明,该方法通过可靠无创的影像分析和放射成像技术,发现了3种具有不同分子特征的肺癌影像亚型,在降低基因检测问题的同时可有效辅助医师进行精准诊断和个性化治疗,进而提高肺癌患者的治愈生存率。 | 任雪婷 赵涓涓 强彦 Saad Abdul RAUF 刘继华 | 2020 | 计算机科学2020，47，10： | 3 |
| 8 | 层状双氢氧化物(LDHs)的合成及应用(英文)显示文摘Layered double hydroxides, a class of anionic clays possessing sandwich like structure in which negative anions are sandwiched into positively charged metal layers in a repeating manner, have been studied extensively. Layered double hydroxides could be fabricated with combination of different divalent(Cd^(2+), Mn^(2+), Fe^(2+), Pb^(2+)) and trivalent(Al^(3+), Cr^(3+), Fe^(3+)) metals and layered arrangement imparts unique properties such as adsorption properties and catalytic properties in these compounds. Exciting feature of these compounds is the memory effect. There are a number of methods to synthesize these layered compounds, such as co-precipitation, hydrothermal, sol-gel, urea hydrolysis,?etc. The synthesized LDHs can be characterized morphologically and compositionally i.e. scanning electron microscopy, transmission electron microscopy, powder X-Ray diffraction, Mossbauer spectroscopy, thermogravimetric analysis, XPS, etc. The wonderful feature of layered double hydroxides is the pliancy of interlayer space enabling them to accommodate various anionic species, and high surface area making them efficient in numerous applications such as adsorbents, anion exchange, catalysts, and biological compatible. | Saba Jamil Afaaf Rahat Alvi Shanza Rauf Khan Muhammad Ramzan Saeed Ashraf Janjua | 2019 | 化学进展2019，31，2： | 3 |
| 9 | Quantitative prediction of the bitterness of atomoxetine hydrochloride and taste-masked using hydroxypropyl-β-cyclodextrin:A biosensor evaluation and interaction study显示文摘The bitterness of a drug is a major challenge for patient acceptability and compliance,especially for children.Due to the toxicity of medication,a human taste panel test has certain limitations.Atomoxetine hydrochloride(HCl),which is used for the treatment of attention deficit/hyperactivity disorder(ADHD),has an extremely bitter taste.The aim of this work is to quantitatively predict the bitterness of atomoxetine HCl by a biosensor system.Based on the mechanism of detection of the electronic tongue(Etongue),the bitterness of atomoxetine HCl was evaluated,and it was found that its bitterness was similar to that of quinine HCl.The bitterness threshold of atomoxetine HCl was 8.61μg/ml based on the Change of membrane Potential caused by Adsorption(CPA)value of the BT0 sensor.In this study,the taste-masking efficiency of 2-hydroxypropyl-β-cyclodextrin(HP-β-CyD)was assessed by Euclidean distances on a principle component analysis(PCA)map with the SA402B Taste Sensing System,and the host–guest interactions were investigated by differential scanning calorimetry(DSC),powder X-ray diffraction(XRD),nuclear magnetic resonance(NMR)spectroscopy and scanning electron microscopy(SEM).Biosensor evaluation and characterization of the inclusion complex indicated that atomoxetine HCl could actively react with 2-hydroxypropyl-β-cyclodextrin. | Shuying Li Ying Zhang Abdur Rauf Khan Shuwang He Yingxin Wang Jiangkang Xu Guangxi Zhai | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，4： | 2 |
| 10 | Breaking wheat yield barriers requires integrated efforts in developing countries显示文摘Most yield progress obtained through the so called 'Green Revolution', particularly in the irrigated areas of Asia, has reached a limit, and major resistance genes are quickly overcome by the appearance of new strains of disease causing organisms.New plant stresses due to a changing environment are difficult to breed for as quickly as the changes occur.There is consequently a continual need for new research programs and breeding strategies aimed at improving yield potential, abiotic stress tolerance and resistance to new, major pests and diseases.Recent advances in plant breeding encompass novel methods of expanding genetic variability and selecting for recombinants, including the development of synthetic hexaploid, hybrid and transgenic wheats.In addition, the use of molecular approaches such as quantitative trait locus(QTL) and association mapping may increase the possibility of directly selecting positive chromosomal regions linked with natural variation for grain yield and stress resistance.The present article reviews the potential contribution of these new approaches and tools to the improvement of wheat yield in farmer's fields, with a special emphasis on the Asian countries, which are major wheat producers, and contain the highest concentration of resource-poor wheat farmers. | Saeed Rauf Maria Zaharieva Marilyn L Warburton ZHANG Ping-zhi Abdullah M AL-Sadi Farghama Khalil Marcin Kozak Sultan A Tariq | 2015 | Journal of Integrative Agriculture2015，14，8： | 2 |
| 11 | Bioassay-guided isolation of novel and selective urease inhibitors from Diospyros lotus显示文摘Two new dimeric naphthoquinones, 5′,8′-dihydroxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(1; Di-naphthodiospyrol D) and 5′,8′-dihydroxy-5,8-dimethoxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(2; Di-naphthodiospyrol E), along with known naphthoquinones diospyrin(3) and 8-hydroxy diospyrin(4) were isolated from the chloroform fraction of extract of Diospyros lotus roots. Their structures were elucidated by advanced spectroscopic analyses, including HSQC, HMBC, NOESY, and J-resolved NMR experiments. The fractions and compounds 1-4 were evaluated for urease activity and phosphodiesterase-Ⅰ, carbonic anhydrase-Ⅱ and α-chymotrypsin enzyme inhibitory activities. Compounds 1 and 2 and their corresponding fractions showed significant and selective inhibitory effects on urease activities. The IC_(50) values of 1 and 2 were 260.4 ± 6.37 and 381.4 ± 4.80 μmol·L-1, respectively, using thiourea(IC_(50) = 21 ± 0.11 μmol·L^(-1)) as the standard inhibitor. This was the first report demonstrating that the naphthoquinones class showed urease inhibition. | Abdur Rauf Ghias Uddin Bina S. Siddiqui Ajmal Khan Umar Farooq Farhan A. Khan Syed Majid Bukhari Sher Bahadar Khan | 2017 | Chinese Journal of Natural Medicines2017，15，11： | 2 |
| 12 | On the radar frequency dependence of polar mesosphere summer echoes显示文摘Polar mesosphere summer echoes(PMSEs)are very strong radar echoes in the polar mesopause in local summer.Here we present the frequency dependence of the volume reflectivity and the effect of energetic particle precipitation on modulated PMSEs by using PMSEs observations carried out by European Incoherent SCATter(EISCAT)heating equipment simultaneously with very high frequency(VHF)radar and ultra high frequency(UHF)radar on 12 July 2007.According to the experimental observations,the PMSEs occurrence rate at VHF was much higher than that at UHF,and the altitude of the PMSEs maximum observed at VHF was higher than that at UHF.Overlapping regions were observed by VHF radar between high energetic particle precipitation and the PMSEs.In addition,highfrequency heating had a very limited impact on PMSEs when the UHF electron density was enhanced because of energetic particle precipitation.In addition,an updated qualitative method was used to study the relationship between volume reflectivity and frequency.The volume reflectivity was found to be inversely proportional to the fourth power of radar frequency.The theoretical and experimental results provide a definitive data foundation for further analysis and investigation of the physical mechanism of PMSEs. | ShuCan Ge HaiLong Li Lin Meng MaoYan Wang Tong Xu Safi Ullah Abdur Rauf Abdel Hannachid | 2020 | Earth and Planetary Physics2020，4，6： | 2 |
| 13 | Sedative and antinociceptive activities of two new sesquiterpenes isolated from Ricinus communis显示文摘Two new sesquiterpenes, trivially named ricinusoids A(1) and ricinusoids B(2), were isolated from ethyl acetate fraction of Ricinus communis. The structures of new compounds were elucidated by detailed spectroscopic techniques, including 1 D-and 2 D-NMR, UV, IR spectroscopy, and mass spectrometry. The compounds(1-2) were also assessed for in-vivo sedative and analgesic like effects in open field and acetic acid induced writhing tests respectively at 5, 10, and 20 mg·kg^(–1) i.p. Pretreatment of both test compounds caused significant(P ≤ 0.05) reduction in locomotive activity like sedative agents and abdominal constrictions like analgesics. Both compounds(1-2) possessed marked sedative and antinociceptive effects in animal models. | Umar Farooq Ajmal Khan Sadia Naz Abdur Rauf Haroon Khan Afsar Khan Irfan Ullah Syed Majid Bukhari | 2018 | Chinese Journal of Natural Medicines2018，16，3： | 2 |
| 14 | Anti-nociceptive, anti-inflammatory and sedative activities of the extracts and chemical constituents of Diospyros lotus L.显示文摘 | Ghias Uddin Abdur Rauf Bina S. Siddiqui Naveed Muhammad Ajmal Khan Syed Uzair Ali Shah | 2014 | Phytomedicine2014，，： | 1 |
| 15 | Fundamental principles and application of heterogeneous photocatalytic degradation of dyes in solution显示文摘 | RAUF M A ASHRAF S S | 2009 | Chemical Engineering Journal2009，151，1： | 1 |
| 16 | Adsorption of dyes from aqueous solutions onto sand and their kinetic behavior显示文摘 | Rauf M A Bukallah S B Hamour F A | 2008 | Chemical Engineering Journals2008，137，2： | 1 |
| 17 | Response surface meth odology (RSM) analysis of photoinduced decoloration of toludine blue 显示文摘 | KORBAHTI B K RAUF M A | 2008 | Chemical Engineering Journal2008，136，1： | 1 |
| 18 | Thermodynamic studies of Ni (II) adsorption onto bentonite from aqueous solution 显示文摘 | Tahir S S Rauf N | 2003 | Journal of Chemical Thermodynamics2003，35，12： | 1 |
| 19 | An overview on thephotocatalytic degradation of azo dyes in the presence ofTiO2 doped with selective transition metals显示文摘 | Rauf M A Meetani M A Hisaindee S | 2011 | Desalina-tion2011，276，： | 1 |
| 20 | Effect of temperature and ero- sion on pitting corrosion of XlOO steel in aqueous silica slur- ries containing bicarbonate and chloride content显示文摘 | Mahdi E Rauf A Eltai E 0 | 2014 | Corro- sion Science2014，83，6： | 1 |
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