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651篇 您的检索式:作者名="Esen"
    题名 作者 年代 出处 被引量
1m^6A mRNA methylation sustains Treg suppressive functions显示文摘Jiyu Tong Guangchao Cao Ting Zhang Esen Sefik Maria Carolina Amezcua Vesely James P Broughton Shu Zhu Huabin Li Bin Li Lei Chen Howard Y Chang Bing Su Richard A Flavell Hua-Bing Li 2018Cell Research2018,28,2:30
2Bone marrow biopsy findings in brucellosis patients with hematologic abnormalities显示文摘Cengiz Demir Mustafa Kasim Karahocagil Ramazan Esen Murat Atmaca Hayriye Gonullu Hayrettin Akdeniz 2012Chinese Medical Journal2012,,11:12
3A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion显示文摘heterodimeric 的激活(α /β) 由 cytosolic 蛋白质 talin 的 integrin transmembrane 受体为调整多样的 cell-adhesion-dependent 过程是关键的包括血凝结,改变的组织,和癌症转移。这进程被 talin (talin-FERM ) 的 N 终端 FERM (four-point-one-protein/ezrin/radixin/moesin ) 领域的重合的绑定触发到内部膜表面和 integrin β细胞质的尾巴,但是这些有约束力的事件怎么空间与时间地被调整,仍然保持阴暗。这里,我们报导休眠 talin 的水晶结构,揭示怎么一个 C 终端 talin 杆片断(talin-RS ) 自我面具经由一个大接口的 talin-FERM 上的一个关键 integrin 有约束力的地点。出人意料地,结构也在静电地妨碍 talin-FERM 绑定到膜的 talin-RS 上揭示不同否定地控告的表面。为 talin 的如此的双禁止的拓扑学与生物化学、功能的数据一致,但是与一个以前的模型显著地不同。我们与 phosphotidylinositol-4,5-bisphosphate (PIP2 ) 在丰富之上显示出那 - 已知的 talin 使活跃之物,膜强烈在 talin-FERM 上吸引断然控告的表面并且同时在 talin-RS 上排斥否定地控告的表面。如此的静电的 “ pull-push”过程支持 talin-FERM 的双抑制的消除,它不同于经典 “位的 clash”为常规导致 PIP2 的 FERM 领域激活当模特儿。这些数据因此解开膜依赖者 FERM 领域规定的一种新类型并且说明它怎么调停 talin 开/关换到调整 integrin transmembrane 发信号和房间粘附。Xianqiang Song Jun Yang Jamila Hirbawi Sheng Ye H Dhanuja Perera Esen Goksoy Pallavi Dwivedi Edward F Plow Rongguang Zhang Jun Qin 2012Cell Research2012,22,11:5
4Is hemodialysis a reason for unresponsiveness to hepatitis B vaccine? Hepatitis B virus and dialysis therapy显示文摘Impaired renal function is associated with a high risk of chronicity of hepatitis B virus(HBV) infection.Patients on hemodialysis(HD) or peritoneal dialysis are at an increased risk of viral transmission due to frequent necessity of blood product transfer as well as use of contaminated dialysate or dialysis materials.Additionally,health professionals may cause viral spread via contaminated hands and carelessness against hygiene rules.The frequency of chronic HBV infection may be as high as 80% in patients on renal replacement therapies.This is because HBV vaccination is essential to eliminate chronic HBV infection.However,response rates of HD patients to HBV vaccination vary between 10%-50%.Dialysis adequacy and early vaccination before the onset of dialysis therapy seem to be major determinants of high seroconversion rates.Older age,male gender,duration of dialysis therapy and nutritional status are other well-known factors associated with seroconversion rate.There are controversial reports regarding the role of the presence of diabetes mellitus,HCV positivity,erythropoietin resistance,hyperparathyroidism,and vitamin D inadequacy.The role of genetic alteration in the functions or production of cytokines still needs to be elucidated.Dede Sit Bennur Esen Ahmet Engin Atay Hasan Kayabasi 2015World Journal of Hepatology2015,7,5:3
5Human adipose derived stem cells are superior to human osteoblasts (HOB) in bone tissue engineering on a collagen-fibroin-ELR blend显示文摘The ultrastructure of the bone provides a unique mechanical strength against compressive, torsional andtensional stresses. An elastin-like recombinamer (ELR) with a nucleation sequence for hydroxyapatitewas incorporated into films prepared from a collagen-silk fibroin blend carrying microchannel patternsto stimulate anisotropic osteogenesis. SEM and fluorescence microscopy showed the alignment ofadipose-derived stem cells (ADSCs) and the human osteoblasts (HOBs) on the ridges and in the groovesof microchannel patterned collagen-fibroin-ELR blend films. The Young's modulus and the ultimatetensile strength (UTS) of untreated films were 0.58 ± 0.13 MPa and 0.18 ± 0.05 MPa, respectively. After 28days of cell culture, ADSC seeded film had a Young's modulus of 1.21 ± 0.42 MPa and UTS of0.32 ± 0.15 MPa which were about 3 fold higher than HOB seeded films. The difference in Young'smodulus was statistically significant (p: 0.02). ADSCs attached, proliferated and mineralized better thanthe HOBs. In the light of these results, ADSCs served as a better cell source than HOBs for bone tissueengineering of collagen-fibroin-ELR based constructs used in this study. We have thus shown theenhancement in the tensile mechanical properties of the bone tissue engineered scaffolds by usingADSCs.Esen Sayin Rosti Hama Rashid JoséCarlos Rodríguez-Cabello Ahmed Elsheikh Erkan Türker Baran Vasif Hasirci 2017Bioactive Materials2017,2,2:2
6Structural and Optical Properties of Zinc Nitride Films Prepared by Pulsed Filtered Cathodic Vacuum Arc Deposition显示文摘多晶的锌氮化物电影被搏动的过滤 cathodic 真空弧免职(PFCVAD ) 在 Corning 7059 玻璃底层上扔。结晶的结构借助于 X 光衍射被学习。这些大小证明所有这些电影在立方的结构被使结晶,在比较喜欢的取向沿着(332 ) 并且(631 ) 方向。弱 XRD 信号显示出在非结晶的纸巾散布的小雏晶。crystallinity 的小改进与退火被观察。光参数象吸收那样,精力乐队差距, Urbach 尾巴,扑灭系数被决定了。Urbach 尾巴精力与在 500 ° C 退火一个小时被减少。精力乐队差距价值被发现被退火增加。SENADIM TUZEMEN Ebru KAVAK Hamide ESEN Ramazan 2007Chinese Physics Letters2007,24,12:2
7Physical and mechanical properties of some hybrid corn varieties显示文摘The aim of this study was to determine the structural designing parameters of silo and bins used for storage of some hybrid corn varieties(Zea mays L.).In the research,three corn varieties-dentcorn(Zea mays indentata Sturt.),popcorn(Zea mays everta Sturt.),sweetcorn(Zea mays sacharata Sturt.)-widespread cultivated in Turkey were used.Physico-mechanical parameters(bulk density,true density,angle of internal friction,static coefficient of friction)were considered as the dependent variables,and moisture content(8%,10%,12%,and 14%)as the independent variable.The bulk density,true density and angle of internal friction varied from 608.46 to 856.46 kg/m^(3),950.88 to 1110.89 kg/m^(3),and 25.2°to 34.2°,respectively,with the increase in moisture content from 8% to 14%.According to results of the research,the highest average value for bulk density,true density,angle of internal friction were found in popcorn variety(839.17 kg/m^(3)),popcorn variety(1074.40 kg/m^(3)),sweetcorn variety(30.50°),respectively.The highest average value for static coefficient of friction at concrete surface(C30)was recorded in dentcorn variety(0.662).TurgutÖztürk Bilge Esen 2013International Journal of Agricultural and Biological Engineering2013,6,1:2
8Clinical Review: Topical Ophthalmic Use of Cyclosporin A显示文摘Canan Asli Utine Michael Stern Esen K. Akpek 2010Ocular Immunology and Inflammation2010,,5:2
9The effect of α-blocker therapy on erectile functions in patients with lower urinary tract symptoms due to benign prostate hyperplasia显示文摘Omer Demir Ismail Ozdemir Ozan Bozkurt Guven Asian Ahmet Adil Esen 2009Asian Journal of Andrology2009,11,6:2
10Identification, synthesis and characterization of process related impurities of benidipine hydrochloride, stress-testing/stability studies and HPLC/UPLC method validations显示文摘Benidipine hydrochloride, used as an antihypertensive agent and long-acting calcium antagonist, is synthesized for commercial use as a drug substance in highly pure form. During the synthetic process development studies of benidipine, process related impurities were detected. These impurities were identi fi ed, synthesized and characterized and mechanisms of their formation were discussed in detail.After all standardization procedures, they were used as reference standards for analytical studies. In addition, a separate HPLC method was developed and validated for detection of residual 1-benzylpiperidin-3-ol(Ben-2), which is used during benidipine synthesis and controlled as a potential process related impurity. As complementary of this work, stress-testing studies of benidipine were carried out under speci fi ed conditions and a stability-indicating UPLC assay method was developed, validated and used during stability studies of benidipine.Esen Bellur Atici Bekir Karl??a 2015Journal of Pharmaceutical Analysis2015,5,4:2
11Hemangioma of the glans penis treated with Nd:YAG laser显示文摘Ulker V Esen T 2005Int Urol Nephrol2005,37,1:1
12Factors affecting results of patients with humeral proximal end fractures undergoing primary hemiarthroplasty:a retrospective study in 42 patients显示文摘Esen E Dogramaci Y Gultekin S 2009Injury2009,40,12:1
13Economics and politics of cross-border oil pipelines the case of the Caspian basin显示文摘RABALLAND G ESEN F 2006Asia Europe Journal2006,5,1:1
14Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells显示文摘Esen M Schreiner B Jendrossek V 2001Apoptosis2001,6,:1
15Effects of low-in-tensity pulsed ultrasound on healing of mandibular frac-tures: An experimental study in rabbits显示文摘Erdogan 0 Esen E Usttin Y 2006J Oral Maxil-lofac Surg2006,64,2:1
16Forecasting of a ground-coupled heat pump performance using neural networks with statistical data weighting pre-processing 显示文摘Hikmet Esen Mustafa Inalli Abdulkadir Sengur 2008International Journal of Thermal Sciences2008,47,4:1
17Lysosomal pathways to cell death and their therapeutic applications显示文摘esen M H Pegan K Spes A 2012Exp Cell Res2012,318,11:1
18Comparison of the effects of an adhe- sion barrier and chitin on experimental epidural fibrosis 显示文摘Keskin F Esen H 2010Turk Neurosurg2010,20,4:1
19An inflammatory verrueous epider- mal nevus concomitant with psoriasis: treatment with adalimumab显示文摘Ozdemir M Balevi A Esen H 2012Dermatol Online J2012,18,10:1
20Artificial neural networks and adaptive neuro-fuzzy assessments for groundcoupled heat pump system 显示文摘Hikmet Esen Mustafa Inalli Abdulkadir Sengur 2008Energy and Buildings2008,40,6:1
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