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| 1 | sTREM-1 is a specific biomarker of TREM-1 pathway activation显示文摘TREM-1(triggering receptor expressed on myeloid cells-1)is a transmembrane receptor expressed by innate immune cells,including endothelial cells and platelets.TREM-1 is a crucial mediator of septic shock that acts by synergizing with Toll-like receptors(TLRs)to amplify the inflammatory responses to pathogens,thus promoting sepsis-induced immune dysregulation and organ dysfunction[1,2,3]. | Lucie Jolly Kévin Carrasco Margarita Salcedo-Magguilli Jean-Jacques Garaud Simon Lambden Tom van der Poll Alexandre Mebazaa Pierre-François Laterre Sebastien Gibot Amir Boufenzer Marc Derive | 2021 | Cellular & Molecular Immunology2021，18，8： | 8 |
| 2 | Reductive cleavage of Demeton-S-methyl by Corynebacterium glutamicum in cometabolism on more readily metabolizable substrates显示文摘 | LAURENCE G DIDIER H SEBASTIEN K | 2000 | Appl Environ Microbiol2000，66，： | 1 |
| 3 | A CGCM study on the interaction between IODand ENSO显示文摘 | BEHERA S K LUO Jingjia SEBASTIEN MASSON | 2006 | Journal of Climate2006，19，9： | 1 |
| 4 | Global prevalence of hepatitis B virus serological markers among healthcare workers:A systematic review and meta-analysis显示文摘BACKGROUND The hepatitis B virus(HBV)infection is a global public health concern that affects about 2 billion people and causes 1 million people deaths yearly.HBV is a bloodborne disease and healthcare workers(HCWs)are a high-risk group because of occupational hazard to patients’blood.Different regions of the world show a highly variable proportion of HCWs infected and/or immunized against HBV.Global data on serologic markers of HBV infection and immunization in HCWs are very important to improve strategies for HBV control.AIM To determine the worldwide prevalence of HBV serological markers among HCWs.METHODS In this systematic review and meta–analyses,we searched PubMed and Excerpta Medica Database(Embase)to identify studies published between 1970 and 2019 on the prevalence of HBV serological markers in HCWs worldwide.We also manually searched for references of relevant articles.Four independent investigators selected studies and included those on the prevalence of each of the HBV serological markers including hepatitis B surface antigen(HBsAg),hepatitis e antigen(HBeAg),immunoglobulin M anti-HBc,and anti-HBs.Methodological quality of eligible studies was assessed and random-effect model meta-analysis resulted in the pooled prevalence of HBV serological markers HBV infection in HCWs.Heterogeneity(I²)was assessed using theχ²test on Cochran’s Q statistic and H parameters.Heterogeneity’sources were explored through subgroup and metaregression analyses.This study is registered with PROSPERO,number CRD42019137144.RESULTS We reviewed 14059 references,out of which 227 studies corresponding to 448 prevalence data among HCWs(224936 HCWs recruited from 1964 to 2019 in 71 countries)were included in this meta-analysis.The pooled seroprevalences of current HBsAg,current HBeAg,and acute HBV infection among HCWs were 2.3%[95% confidence interval(CI):1.9-2.7],0.2%(95%CI:0.0-1.7),and 5.3%(95%CI:1.4-11.2),respectively.The pooled seroprevalences of total immunity against HBV and immunity acquired by natural HBV infection in HCWs were 56.6%(95%CI:48.7-63.4)and 9.2%(95%CI:6.8-11.8),respectively.HBV infection was more prevalent in HCWs in low-income countries,particularly in Africa.The highest immunization rates against HBV in HCWs were recorded in urban areas and in high-income countries including Europe,the Eastern Mediterranean and the Western Pacific.CONCLUSION New strategies are needed to improve awareness,training,screening,vaccination,post-exposure management and treatment of HBV infection in HCWs,and particularly in low-income regions. | Gadji Mahamat Sebastien Kenmoe Etheline W Akazong Jean Thierry Ebogo-Belobo Donatien Serge Mbaga Arnol Bowo-Ngandji Joseph Rodrigue Foe-Essomba Marie Amougou-Atsama Chavely Gwladys Monamele Chris Andre Mbongue Mikangue Ginette Irma Kame-Ngasse Jeannette Nina Magoudjou-Pekam Cromwel Zemnou-Tepap Dowbiss Meta-Djomsi Martin Maidadi-Foudi Sabine Aimee Touangnou-Chamda Audrey Gaelle Daha-Tchoffo Abdel Aziz Selly-Ngaloumo Rachel Audrey Nayang-Mundo Jacqueline Felicite Yengue Jean Bosco Taya-Fokou Lorraine K M Fokou Raoul Kenfack-Momo Dimitri Tchami Ngongang Efietngab Atembeh Noura Herve Raoul Tazokong Cynthia Paola Demeni Emoh Cyprien Kengne-Nde Jean Joel Bigna Onana Boyomo Richard Njouom | 2021 | World Journal of Hepatology2021，13，9： | 1 |
| 5 | The absence of intrarenal ACE protects against hypertension显示文摘 | Gonzalez-Villalobos Romer A Janjoulia Tea Fletcher Nicholas K Giani Jorge F Nguyen Mien TX Riquier-Brison Anne D Seth Dale M Fuchs Sebastien Eladari Dominique Picard Nicolas Bachmann Sebastian Delpire Eric Peti-Peterdi Janos Navar L Gabriel | 2013 | Journal of Clinical Investigation2013，，5： | 1 |
| 6 | Total-coloring of plane graphs with maximum degree nine 显示文摘 | Lukasz K Jean Sebastien S Riste S | 2008 | Discrete Mathe- matics2008，22，： | 1 |
| 7 | Apple Peels, from Seven Cultivars, Have Lipase-Inhibitory Activity and Contain Numerous Ursenoic Acids As Identified by LC-ESI-QTOF-HRMS显示文摘 | Tony K MeGhie Sebastien Hudauh | 2012 | J Agric Food Chem2012，60，1： | 1 |
| 8 | Extended ENSO Predictions Using a Fully Coupled Ocean-Atmosphere Model显示文摘 | Luo Jing-Jia Masson Sebastien Behera Swadhin K Yamagata Toshio | 2008 | Journal of Climate2008，，1： | 1 |
| 9 | Logic-based approaches to information fusion显示文摘 | Eric G Sebastien K | 2006 | Information Fusion2006，7，1： | 1 |
| 10 | Critical Role ofserum response factor in pulmonary myofibroblast differentiationinduced by TGF-β显示文摘 | NATHAN S STEVEN K SEBASTIEN T | 2009 | Am J Respir Cell Mol Biol2009，41，3： | 1 |
| 11 | In vitro and in situ study of postharvest apple blue mold biocontrol by Aureobasidiumpullulans: Evidence for the involvement of competition for nutrients显示文摘 | Sanae K B Mohammed B Sebastien M | 2007 | Postharvest Biology and Technology2007，46，2： | 1 |
| 12 | Possible cause of excess sludge reduction in an oxic-settling-anaerobic activated sludge process(OSA process)显示文摘 | K young-Jin An Sebastien Saby etl | 2003 | Water Research2003，37，16： | 1 |
| 13 | The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor显示文摘 | Elias A Bernard K Sebastien N | 2002 | Am Soc Biochem Molr Biol2002，227，37： | 1 |
| 14 | Dense matter with eXTP显示文摘In this White Paper we present the potential of the Enhanced X-ray Timing and Polarimetry(eXTP) mission for determining the nature of dense matter; neutron star cores host an extreme density regime which cannot be replicated in a terrestrial laboratory. The tightest statistical constraints on the dense matter equation of state will come from pulse profile modelling of accretion-powered pulsars, burst oscillation sources, and rotation-powered pulsars. Additional constraints will derive from spin measurements, burst spectra, and properties of the accretion flows in the vicinity of the neutron star. Under development by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Sciences, the eXTP mission is expected to be launched in the mid 2020 s. | Anna L.Watts WenFei Yu Juri Poutanen Shu Zhang Sudip Bhattacharyya Slavko Bogdanov Long Ji Alessandro Patruno Thomas E.Riley Pavel Bakala Altan Baykal Federico Bernardini Ignazio Bombaci Edward Brown Yuri Cavecchi Deepto Chakrabarty Jér?me Chenevez Nathalie Degenaar Melania Del Santo Tiziana Di Salvo Victor Doroshenko Maurizio Falanga Robert D.Ferdman Marco Feroci Angelo F.Gambino MingYu Ge Svenja K.Greif Sebastien Guillot Can Gungor Dieter H.Hartmann Kai Hebeler Alexander Heger Jeroen Homan Rosario Iaria Jean in 't Zand Oleg Kargaltsev Aleksi KurkelaTheoretical Physics Department CERN XiaoYu Lai Ang Li XiangDong Li ZhaoSheng Li Manuel Linares FangJun Lu Simin Mahmoodifar Mariano Méndez M.Coleman Miller Sharon Morsink Joonas N?ttil? Andrea Possenti Chanda Prescod-Weinstein JinLu Qu Alessandro Riggio Tuomo Salmi Andrea Sanna Andrea Santangelo Hendrik Schatz Achim Schwenk LiMing Song Eva?rámková Benjamin Stappers Holger Stiele Tod Strohmayer Ingo Tews Laura Tolos Gabriel T?r?k David Tsang Martin Urbanec Andrea Vacchi RenXin Xu YuPeng Xu Silvia Zane GuoBao Zhang ShuangNan Zhang WenDa Zhang ShiJie Zheng Xia Zhou | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 0 |
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